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Jaguar Animal Health Inc. (JAGX)
:JAGX

Jaguar Animal Health (JAGX) AI Stock Analysis

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Jaguar Animal Health

(NASDAQ:JAGX)

39Underperform
Jaguar Animal Health's overall stock score is low primarily due to substantial financial challenges, including high leverage and negative profitability. Technical analysis suggests bearish trends, and valuation metrics are unappealing. While recent earnings calls and corporate events provide some optimism with revenue growth and potential regulatory advancements, ongoing net losses and clinical trial challenges continue to weigh heavily on the stock's potential.

Jaguar Animal Health (JAGX) vs. S&P 500 (SPY)

Jaguar Animal Health Business Overview & Revenue Model

Company DescriptionJaguar Health, Inc., a commercial stage pharmaceuticals company, focuses on developing prescription medicines for people and animals with gastrointestinal distress, specifically chronic, and debilitating diarrhea. The company operates through two segments, Human Health and Animal Health. It markets Mytesi for the symptomatic relief of noninfectious diarrhea in adults with HIV/AIDS on antiretroviral therapy. The company also develops Crofelemer for multiple possible follow-on indications, including cancer therapy-related diarrhea; orphan-drug indications for symptomatic relief of diarrhea in infants and children with congenital diarrheal disorders and for adult and pediatric patients for short bowel syndrome with intestinal failure with; supportive care for diarrhea relief in inflammatory bowel diseases; diarrhea-predominant irritable bowel syndrome; and for idiopathic/functional diarrhea. In addition, it develops lechlemer, a second-generation anti-secretory agent for cholera; and Canalevia, an oral plant-based drug candidate to treat chemotherapy-induced diarrhea in dogs and exercise-induced diarrhea in dogs. Jaguar Health, Inc. was founded in 2013 and is headquartered in San Francisco, California.
How the Company Makes MoneyJaguar Animal Health generates revenue through the sale of its proprietary pharmaceutical products and royalties from licensing agreements. The company's primary revenue stream comes from the commercialization of Canalevia-CA1, which is sold to veterinary clinics and specialists to treat gastrointestinal conditions in dogs. In addition to direct sales, Jaguar benefits from strategic partnerships and collaborations that expand its research and distribution capabilities, including licensing agreements with pharmaceutical companies that enable it to earn royalties on products developed using its technology. These partnerships also contribute to the company's earnings by providing additional avenues for product development and market penetration.

Jaguar Animal Health Financial Statement Overview

Summary
Jaguar Animal Health is experiencing revenue growth but faces significant profitability and liquidity challenges. The company struggles with substantial losses, a high debt-to-equity ratio, and negative cash flow.
Income Statement
35
Negative
Jaguar Animal Health shows persistent revenue growth, with a TTM revenue of $10.48M, up from $9.76M in 2023. However, the company is struggling with profitability, evidenced by a negative net profit margin and significant EBIT and EBITDA losses. The gross profit margin remains healthy at approximately 68.6%, but the net loss indicates ongoing financial challenges.
Balance Sheet
40
Negative
The balance sheet reveals a high debt-to-equity ratio and limited equity base, with stockholders' equity at $13.61M against $34.27M in total debt. The equity ratio stands at 23.3%, indicating financial leverage concerns. Despite these challenges, there is a noteworthy improvement in stockholders' equity from negative values in previous years.
Cash Flow
30
Negative
The cash flow statement highlights negative operating cash flow and free cash flow, reflecting liquidity issues. The free cash flow growth rate is improving, but the company is still heavily reliant on financing activities. The operating cash flow to net income ratio is negative, emphasizing ongoing cash management challenges.
Breakdown
Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019
Income StatementTotal Revenue
9.76M11.96M4.33M9.38M5.78M
Gross Profit
7.72M9.94M2.00M6.11M1.96M
EBIT
-34.29M-34.41M-39.07M-21.30M-24.95M
EBITDA
-33.13M-33.38M-42.35M-28.74M-30.87M
Net Income Common Stockholders
-41.30M-47.45M-60.25M-36.79M-38.54M
Balance SheetCash, Cash Equivalents and Short-Term Investments
6.47M5.47M17.05M8.09M3.50M
Total Assets
50.76M47.45M53.27M42.84M36.41M
Total Debt
37.09M34.84M29.36M16.21M7.57M
Net Debt
30.63M29.37M12.31M8.12M4.07M
Total Liabilities
45.87M48.81M41.41M25.64M25.74M
Stockholders Equity
4.96M-657.00K11.61M17.20M10.67M
Cash FlowFree Cash Flow
-33.24M-34.78M-34.98M-15.29M-20.46M
Operating Cash Flow
-33.24M-33.10M-34.97M-15.28M-20.46M
Investing Cash Flow
0.00-1.68M-6.00K-7.00K0.00
Financing Cash Flow
34.23M23.18M43.94M19.49M21.77M

Jaguar Animal Health Technical Analysis

Technical Analysis Sentiment
Positive
Last Price10.91
Price Trends
50DMA
10.48
Positive
100DMA
17.15
Negative
200DMA
26.24
Negative
Market Momentum
MACD
-0.44
Negative
RSI
70.55
Negative
STOCH
70.58
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JAGX, the sentiment is Positive. The current price of 10.91 is above the 20-day moving average (MA) of 5.61, above the 50-day MA of 10.48, and below the 200-day MA of 26.24, indicating a neutral trend. The MACD of -0.44 indicates Negative momentum. The RSI at 70.55 is Negative, neither overbought nor oversold. The STOCH value of 70.58 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for JAGX.

Jaguar Animal Health Risk Analysis

Jaguar Animal Health disclosed 65 risk factors in its most recent earnings report. Jaguar Animal Health reported the most risks in the “Finance & Corporate” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Jaguar Animal Health Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$5.31B3.39-40.42%2.90%18.11%2.25%
41
Neutral
$3.46M-163.47%-100.00%78.91%
39
Underperform
$7.35M-522.60%19.75%95.65%
35
Underperform
$3.38M-103.63%-100.00%28.48%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JAGX
Jaguar Animal Health
10.67
-301.33
-96.58%
TTNP
Titan Pharmaceuticals
3.84
-3.01
-43.94%
ATNF
180 Life Sciences
0.88
-1.08
-55.10%
NLSP
NLS Pharmaceutics
1.47
-4.20
-74.07%
SPRC
SciSparc Ltd.
0.28
-1.14
-80.28%
HSCS
Heart Test Laboratories, Inc.
3.35
-6.29
-65.25%

Jaguar Animal Health Earnings Call Summary

Earnings Call Date:Mar 31, 2025
(Q4-2024)
|
% Change Since: 118.20%|
Next Earnings Date:May 19, 2025
Earnings Call Sentiment Neutral
The earnings call highlighted significant revenue growth and promising developments in rare disease programs and oncology segments. However, the company continues to face substantial net losses and challenges in clinical trial outcomes. Overall, the company is optimistic about near-term catalysts and regulatory meetings that could enhance value.
Q4-2024 Updates
Positive Updates
Significant Revenue Growth
Net 2024 revenue increased approximately 20%, reaching $11.7 million compared to $9.8 million in 2023. Q4 2024 revenue grew approximately 53% year-over-year and 13% quarter-over-quarter.
Progress in Intestinal Failure Program
Jaguar Health is supporting proof-of-concept trials for crofelemer in rare diseases such as MVID and SBS-IF. First results expected in Q2 2025 could lead to PRIME and FDA breakthrough designations.
Oncology Segment Developments
Despite not meeting primary endpoints in all tumor types, significant results in breast cancer patients were achieved, leading to a scheduled FDA meeting in Q2 2025 to discuss Mytesi's expanded approval.
Improved Loss from Operations
Loss from operations decreased by $3.5 million from $34.3 million in 2023 to $30.8 million in 2024.
Negative Updates
Continued Net Loss
The net loss attributable to common shareholders decreased slightly but remained substantial at $38.5 million in 2024, compared to $41.3 million in 2023.
Challenges in Achieving Primary Endpoints
The Phase 3 trial for Mytesi in cancer therapy-related diarrhea did not meet its primary endpoint across all tumor types.
Company Guidance
During the Jaguar Health Investor Webcast, CEO Lisa Conte reported a 20% increase in net revenue for 2024, reaching approximately $11.7 million compared to $9.8 million in 2023. The company's Q4 2024 net revenue saw a 53% increase over Q4 2023, totaling $3.5 million. Mytesi's prescription volume grew by 3.9% in 2024 and 9.4% in Q4 2024 over Q4 2023. Jaguar is anticipating significant catalysts in Q2 2025, including potential regulatory advancements for crofelemer in treating rare diseases like microvillus inclusion disease and short bowel syndrome. The company is also pursuing expansion of Mytesi's indications to include cancer therapy-related diarrhea in breast cancer patients. Financially, the loss from operations decreased to $30.8 million in 2024, with net loss attributable to common shareholders reducing to $38.5 million.

Jaguar Animal Health Corporate Events

Product-Related AnnouncementsBusiness Operations and Strategy
Jaguar Health Presents at Elite Ped-GI Congress 2025
Positive
Apr 25, 2025

Jaguar Health announced its participation in the 11th Annual Elite Ped-GI Congress 2025 in Abu Dhabi, where they will present proof-of-concept data for their products, including crofelemer. The company is actively pursuing business development opportunities and regulatory designations in the U.S. and Europe, aiming to expand the market reach of crofelemer for various indications, which could significantly impact their market positioning and stakeholder interests.

Spark’s Take on JAGX Stock

According to Spark, TipRanks’ AI Analyst, JAGX is a Neutral.

Jaguar Animal Health is currently facing substantial financial difficulties with high leverage and negative profitability, as reflected in the financial performance and valuation scores. Technical analysis suggests bearish trends, while recent earnings calls and corporate events provide some optimism with revenue growth and potential regulatory advancements. However, the company’s ongoing net losses and challenges in clinical trials continue to weigh on its overall stock score.

To see Spark’s full report on JAGX stock, click here.

Private Placements and Financing
Jaguar Animal Health Secures $3.448M in Private Placement
Positive
Apr 4, 2025

On March 31, 2025, Jaguar Health closed a private placement, raising approximately $3.448 million through convertible promissory notes and warrants. The funds will be used for working capital and general corporate purposes, with expectations of key catalysts in the second quarter of 2025 related to crofelemer development for rare diseases and cancer therapy-related diarrhea, potentially enhancing the company’s value.

Delistings and Listing ChangesStock Split
Jaguar Animal Health Announces Reverse Stock Split
Neutral
Mar 18, 2025

Jaguar Health, Inc. announced a reverse stock split of its common stock at a 1-for-25 ratio, effective March 24, 2025, to comply with Nasdaq listing standards and attract institutional investors. The reverse stock split will reduce the number of shares and increase the share price, with no fractional shares issued; stockholders will receive cash for any fractional shares. The company’s stock will continue trading on Nasdaq under the symbol ‘JAGX’ with a new CUSIP number.

Shareholder MeetingsStock SplitBusiness Operations and Strategy
Jaguar Animal Health Advances Crofelemer for Rare Diseases
Positive
Mar 13, 2025

On March 13, 2025, Jaguar Health held a special meeting where stockholders approved two proposals, including a reverse stock split of the company’s common stock. The company is advancing its plant-based drug, crofelemer, for rare diseases and cancer therapy-related diarrhea, with expected trial results and regulatory discussions in 2025. These developments could enhance Jaguar’s market positioning and offer new treatment pathways, potentially benefiting stakeholders.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.