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Jaguar Animal Health (JAGX)
NASDAQ:JAGX
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Jaguar Animal Health (JAGX) AI Stock Analysis

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JAGX

Jaguar Animal Health

(NASDAQ:JAGX)

Rating:42Neutral
Price Target:
$2.00
▲(2.04% Upside)
Jaguar Animal Health's overall stock score is primarily impacted by its weak financial performance, characterized by high leverage and consistent losses. Technical indicators suggest a bearish trend, and valuation metrics are poor. While the earnings call provided some positive insights, they are overshadowed by ongoing financial challenges.
Positive Factors
Revenue Growth
Consistent revenue growth indicates strong market demand and effective sales strategies, enhancing long-term financial stability.
Regulatory Advancements
Regulatory advancements for crofelemer can expand market access and drive future revenue growth, strengthening the company's competitive position.
Clinical Trial Success
Successful clinical trials enhance product credibility and open new therapeutic markets, supporting long-term growth and innovation.
Negative Factors
High Leverage
High leverage increases financial risk and limits strategic flexibility, potentially impacting future growth and investment capacity.
Negative Cash Flow
Negative cash flow trends indicate challenges in sustaining operations and funding growth, necessitating improved cash management strategies.
Operational Losses
Rising operational losses highlight inefficiencies and cost management issues, which can hinder profitability and long-term sustainability.

Jaguar Animal Health (JAGX) vs. SPDR S&P 500 ETF (SPY)

Jaguar Animal Health Business Overview & Revenue Model

Company DescriptionJaguar Health, Inc., a commercial stage pharmaceuticals company, focuses on developing prescription medicines for people and animals with gastrointestinal distress, specifically chronic, and debilitating diarrhea. The company operates through two segments, Human Health and Animal Health. It markets Mytesi for the symptomatic relief of noninfectious diarrhea in adults with HIV/AIDS on antiretroviral therapy. The company also develops Crofelemer for multiple possible follow-on indications, including cancer therapy-related diarrhea; orphan-drug indications for symptomatic relief of diarrhea in infants and children with congenital diarrheal disorders and for adult and pediatric patients for short bowel syndrome with intestinal failure with; supportive care for diarrhea relief in inflammatory bowel diseases; diarrhea-predominant irritable bowel syndrome; and for idiopathic/functional diarrhea. In addition, it develops lechlemer, a second-generation anti-secretory agent for cholera; and Canalevia, an oral plant-based drug candidate to treat chemotherapy-induced diarrhea in dogs and exercise-induced diarrhea in dogs. Jaguar Health, Inc. was founded in 2013 and is headquartered in San Francisco, California.
How the Company Makes MoneyJaguar Animal Health generates revenue primarily through the sale of its pharmaceutical products and veterinary therapeutics. The company has established a revenue model that includes direct sales to veterinarians and animal health distributors, as well as partnerships with larger pharmaceutical companies for product development and distribution. Key revenue streams include prescription medications and potential royalties from collaborations. Additionally, Jaguar may engage in licensing agreements for its proprietary technologies, further enhancing its financial performance. Significant partnerships with veterinary practices and discussions with animal food companies also contribute to its earnings, as they help broaden the reach and application of its products in the market.

Jaguar Animal Health Earnings Call Summary

Earnings Call Date:Aug 14, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Nov 12, 2025
Earnings Call Sentiment Neutral
The earnings call presented a positive outlook with significant revenue growth and successful clinical trial results for crofelemer, along with strategic regulatory advancements and expansion plans in the animal health market. However, these positive developments were offset by increased operational losses and net loss attributable to shareholders.
Q2-2025 Updates
Positive Updates
Significant Revenue Growth
The second quarter of 2025 saw a combined net revenue of approximately $3 million, representing a 35% increase compared to Q1 2025 and a 10% increase compared to Q2 2024.
Positive Clinical Trial Results for Crofelemer
Initial proof-of-concept results from a study in Abu Dhabi demonstrated that crofelemer reduced the required TPN and supplementary intravenous fluids in MVID and SBS patients by up to 27% and 12.5% respectively.
Regulatory Advancements for Crofelemer
Jaguar participated in an FDA Type C meeting, discussing two pathways for crofelemer's availability for metastatic breast cancer patients, highlighting an expanded access program and a pivotal treatment trial.
Expansion into Animal Health Market
Ongoing discussions with potential partners to expand Canalevia's approval from chemotherapy-induced diarrhea in dogs to general diarrhea in dogs globally.
Negative Updates
Increased Net Loss
Net loss attributable to common shareholders increased by approximately $900,000 from $9.5 million in Q2 2024 to $10.4 million in Q2 2025.
Loss from Operations
Loss from operations increased by $800,000 from $7.2 million in Q2 2024 to $8 million in Q2 2025.
Company Guidance
During the earnings call for the second quarter of 2025, Jaguar Health reported a combined net revenue of approximately $3 million, marking a 35% increase compared to the first quarter of 2025 and a 10% increase compared to the second quarter of 2024. Mytesi prescription volume rose by 6.5% over the previous quarter. However, the company experienced a loss from operations of $8 million, an increase of $800,000 from the same period in 2024, and a net loss attributable to common shareholders of $10.4 million, up by $900,000. The non-GAAP recurring EBITDA showed a net loss reduction from $8.8 million in 2024 to $7.9 million in 2025. The financial guidance emphasized the importance of recent clinical and regulatory catalysts aiming to secure nondilutive funding and forge business development partnerships.

Jaguar Animal Health Financial Statement Overview

Summary
Jaguar Animal Health faces substantial financial challenges characterized by high leverage, consistent net losses, and negative cash flows. Despite some revenue growth and strong gross margins, the company struggles with operational efficiencies and debt management.
Income Statement
35
Negative
Jaguar Animal Health has shown a mixed performance with inconsistent revenue growth. The revenue grew by approximately 18.38% from 2023 to 2024 but showed a decline previously. Gross profit margins are reasonably high, but the company struggles with negative EBIT and net income margins, indicating ongoing operational and profitability challenges.
Balance Sheet
30
Negative
The company's balance sheet indicates high leverage with a Debt-to-Equity ratio of approximately 5.63 in 2024, reflecting significant reliance on debt financing. The return on equity is negative due to consistent net losses, and the equity ratio is low, suggesting financial instability and potential risks related to excessive debt.
Cash Flow
40
Negative
Cash flow analysis reveals a negative trend in free and operating cash flows, although there was a slight improvement from 2023 to 2024. The company managed to secure significant financing cash flows, which have been covering operational deficits. However, the negative free cash flow to net income ratio highlights ongoing cash management issues.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue11.77M11.69M9.76M11.96M4.33M9.38M
Gross Profit9.67M9.73M7.72M9.94M2.00M6.11M
EBITDA-39.29M-36.66M-33.13M-33.38M-42.35M-28.74M
Net Income-40.65M-38.49M-41.30M-47.45M-60.25M-36.79M
Balance Sheet
Total Assets48.27M53.42M50.76M47.45M53.27M42.84M
Cash, Cash Equivalents and Short-Term Investments2.21M8.00M6.47M5.47M17.05M8.09M
Total Debt30.53M36.53M37.09M34.84M29.36M16.21M
Total Liabilities41.39M46.93M45.87M48.81M41.41M25.64M
Stockholders Equity7.99M9.77M4.96M-657.00K11.61M17.20M
Cash Flow
Free Cash Flow-27.88M-29.61M-33.24M-34.78M-34.98M-15.29M
Operating Cash Flow-27.68M-29.38M-33.24M-33.10M-34.97M-15.28M
Investing Cash Flow-215.00K-231.00K1.23M-1.68M-6.00K-7.00K
Financing Cash Flow13.98M31.20M34.23M23.18M43.94M19.49M

Jaguar Animal Health Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price1.96
Price Trends
50DMA
2.14
Negative
100DMA
3.97
Negative
200DMA
10.91
Negative
Market Momentum
MACD
-0.07
Negative
RSI
48.99
Neutral
STOCH
75.67
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JAGX, the sentiment is Neutral. The current price of 1.96 is above the 20-day moving average (MA) of 1.84, below the 50-day MA of 2.14, and below the 200-day MA of 10.91, indicating a neutral trend. The MACD of -0.07 indicates Negative momentum. The RSI at 48.99 is Neutral, neither overbought nor oversold. The STOCH value of 75.67 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for JAGX.

Jaguar Animal Health Risk Analysis

Jaguar Animal Health disclosed 65 risk factors in its most recent earnings report. Jaguar Animal Health reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Jaguar Animal Health Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$8.02B-0.31-43.38%2.24%22.31%-2.14%
42
Neutral
$4.41M-296.91%15.95%92.33%
41
Neutral
$5.83M-285.78%120.67%-456.33%
39
Underperform
$11.91M-402.19%59.81%
28
Underperform
$8.49M-53.99%56.31%
28
Underperform
$3.40M-340.81%94.99%
15
Underperform
$3.68M-231.27%85.78%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JAGX
Jaguar Animal Health
1.96
-25.54
-92.87%
GLMD
Galmed Pharmaceuticals
1.51
-2.36
-60.98%
SNGX
Soligenix
2.92
-0.59
-16.81%
REVB
Revelation Biosciences
1.92
-41.24
-95.55%
DRMA
Dermata Therapeutics
5.40
-17.80
-76.72%
SXTP
60 Degrees Pharmaceuticals, Inc.
1.40
-5.55
-79.86%

Jaguar Animal Health Corporate Events

Product-Related AnnouncementsShareholder MeetingsBusiness Operations and Strategy
Jaguar Health Announces Promising Trial Results
Positive
Aug 19, 2025

On August 19, 2025, Jaguar Health held its Annual Meeting of Stockholders, where seven proposals were approved, including the election of directors and amendments to stock plans. The company also announced promising results from trials of crofelemer for gastrointestinal conditions and outlined plans for regulatory pathways and business development partnerships, potentially impacting its market strategy and stakeholder interests.

Business Operations and StrategyRegulatory Filings and Compliance
Jaguar Health Extends Market Offering Agreement
Neutral
Aug 14, 2025

On August 14, 2025, Jaguar Health, Inc. announced an amendment to its At the Market Offering Agreement, extending Lucid Capital Markets, LLC’s role as a Manager until December 31, 2025. This amendment, filed with the SEC, ensures that Lucid will continue its managerial role alongside Ladenburg Thalmann & Co. Inc. until the end of 2025, after which Ladenburg will become the sole Manager unless further extended.

Private Placements and FinancingBusiness Operations and Strategy
Jaguar Animal Health Issues Series M Preferred Stock
Neutral
Jun 30, 2025

On June 27, 2025, Jaguar Health, Inc. entered into exchange agreements with Iliad Research and Trading, L.P. and Streeterville Capital, LLC, issuing Series M Preferred Stock in exchange for reductions in outstanding royalty interests. This strategic move allows Jaguar Health to manage its financial obligations while offering stakeholders a structured investment opportunity through the Series M Preferred Stock, which includes specific rights and limitations, impacting the company’s capital structure and market positioning.

Private Placements and FinancingBusiness Operations and Strategy
Jaguar Animal Health Extends Maturity Date for Notes
Neutral
Jun 24, 2025

On June 24, 2025, Jaguar Health, Inc. announced an extension of the maturity date for $2.57 million of convertible promissory notes from its March 2025 bridge financing, now maturing on January 30, 2026. This extension, involving participation from the company’s CEO, board members, and other investors, aims to support Jaguar’s strategic goals, including partnerships for non-dilutive funding and advancing development programs for crofelemer in treating various conditions.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 09, 2025