Soligenix (SNGX) AI Stock Analysis

• Market Cap: $13.92M
• Dividend Yield: N/A
• Average Volume (3M): 351.09K
• Price to Earnings (P/E): ―
• Beta (1Y): 0.28
• Revenue Growth: N/A
• EPS Growth: 53.13%
• Country: US
• Employees: 14
• Sector: Healthcare
• Sector Strength: 45
• Industry: Biotechnology
• EPS (TTM): -0.58
• Shares Outstanding: 10,086,130
• 10 Day Avg. Volume: 158,262
• 30 Day Avg. Volume: 351,092
• PEG Ratio: <0.01
• Price to Book (P/B): 1.09
• Price to Sales (P/S): 37.55
• P/FCF Ratio: -0.53
• Enterprise Value/Market Cap: -0.37
• Enterprise Value/Revenue: N/A
• Enterprise Value/Gross Profit: 7.28K
• Enterprise Value/Ebitda: 0.44
• 1Y Price Target: $10.00
• Price Target Upside: 594.44% Upside
• Rating Consensus: Moderate Buy
• Number of Analyst Covering: 1
• EPS Forecast (FY): -1.3
• Revenue Forecast (FY): $800.00K

• Rating: 43 Neutral
• Price Target: $1.50 ▲(4.17% Upside)

The score is primarily held down by weak financial performance (zero revenue, persistent losses, and continued cash burn), partially offset by balance-sheet improvement from deleveraging and positive equity. Technicals also weigh on the score due to a broadly weak trend, while valuation provides limited support given the negative P/E and lack of dividend data.

Positive Factors

FDA Orphan Drug Designation

The orphan drug designation provides Soligenix with market exclusivity, financial benefits, and regulatory support, enhancing its competitive position in rare disease treatment.

Government Funding

Government funding supports Soligenix's biodefense division, providing a stable financial base and reducing reliance on volatile commercial revenue streams.

Loan Repayment

Repaying the loan enhances Soligenix's financial flexibility, reducing debt burden and improving its ability to invest in core biopharmaceutical operations.

Negative Factors

Revenue Decline

Significant revenue decline indicates challenges in product commercialization and market penetration, threatening long-term financial sustainability.

Negative Cash Flow

Persistent negative cash flow from operations suggests difficulty in generating sufficient cash, potentially impacting future growth and operational stability.

High Financial Leverage

High financial leverage indicates reliance on debt, which can limit financial flexibility and increase risk, especially with ongoing net losses.

Soligenix Business Overview & Revenue Model

Company Description

Soligenix, Inc., a late-stage biopharmaceutical company, focuses on developing and commercializing products to treat rare diseases in the United States. It operates in two segments, Specialized BioTherapeutics and Public Health Solutions. The Specialized BioTherapeutics segment develops SGX301 (HyBryte), a novel photodynamic therapy, which has completed Phase III clinical trial for the treatment of treat cutaneous T-cell lymphoma; and SGX942, an innate defense regulator technology that is in Phase III clinical trial for the treatment of inflammatory diseases, including oral mucositis in head and neck cancer. This segment also offers proprietary formulations of oral beclomethasone 17,21-dipropionate for the prevention/treatment of gastrointestinal disorders characterized by severe inflammation, including SGX203 for pediatric Crohn's disease; and SGX302 that is in Phase I/II clinical trial for the treatment of mild-to-moderate psoriasis. The Public Health Solutions segment is involved in the development of RiVax, a ricin toxin vaccine candidate, which has completed Phase Ia and Ib clinical trials; SGX943, a therapeutic candidate that is in pre-clinical stage for the treatment of antibiotic resistant and emerging infectious diseases; ThermoVax, a technology in pre-clinical development for thermostabilizing vaccines; and CiVax, a vaccine candidate in pre-clinical development for the prevention of COVID-19. The company was formerly known as DOR BioPharma, Inc. and changed its name to Soligenix, Inc. in 2009. Soligenix, Inc. was incorporated in 1987 and is headquartered in Princeton, New Jersey.

How the Company Makes Money

Soligenix makes money primarily through the research, development, and commercialization of its biopharmaceutical products. The company's revenue streams include government grants and contracts, especially for its biodefense programs, as well as potential future revenues from product sales, partnerships, and collaborations with other pharmaceutical companies. Soligenix's financial success is heavily dependent on the successful development and approval of its lead product candidates, which can result in licensing agreements, milestone payments, and royalties. Additionally, its biodefense division benefits from government funding, which supports the development of vaccines and therapeutics for potential bioterrorism threats.

Soligenix Financial Statement Overview

Summary

Soligenix's financial health is concerning, with significant revenue decline, ongoing net losses, and high reliance on external financing. The company faces operational inefficiencies, evident in its negative margins and cash flow challenges. Despite efforts to secure financing, sustainability remains questionable without improvements in revenue and profitability.

Income Statement

Soligenix has experienced significant revenue decline over recent years, with a sharp drop from $4.6M in 2019 to just $119k in 2024. The net profit margin remains deeply negative, with a net loss of $8.7M in 2024. Both EBIT and EBITDA margins are negative, indicating ongoing operational challenges and inefficiencies in cost management. Revenue growth has also been inconsistent, reflecting volatility in business operations.

Balance Sheet

The company's balance sheet shows high financial leverage, with a debt-to-equity ratio fluctuating due to negative equity in some years. In 2024, the equity ratio improved slightly but still indicates reliance on debt financing. Return on equity remains negative due to continued net losses. Total assets have decreased significantly since 2019, reflecting a reduction in company scale and potentially diminishing asset utility.

Cash Flow

Soligenix's cash flow statements highlight consistent negative operating cash flow, indicating challenges in generating cash from core operations. Despite this, financing activities have periodically provided cash infusions, such as in 2024 with $7.7M from financing. Free cash flow remains negative, suggesting persistent cash outflows exceeding cash inflows from operations and investments.

Breakdown	TTM	Dec 2024	Dec 2023	Dec 2022	Dec 2021	Dec 2020
Income Statement
Total Revenue	0.00	0.00	0.00	250.00K	33.35K	1.93M
Gross Profit	-703.00	-119.37K	-742.05K	-300.82K	-695.29K	109.58K
EBITDA	-11.65M	-9.46M	-7.67M	-14.11M	-12.48M	-18.45M
Net Income	-10.65M	-8.27M	-6.14M	-13.80M	-12.55M	-17.69M
Balance Sheet
Total Assets	5.76M	8.97M	9.80M	14.28M	26.87M	19.89M
Cash, Cash Equivalents and Short-Term Investments	5.10M	7.82M	8.45M	13.36M	26.04M	18.68M
Total Debt	411.40K	1.48M	3.49M	10.24M	9.96M	10.51M
Total Liabilities	3.93M	4.85M	7.27M	16.75M	16.15M	16.15M
Stockholders Equity	1.83M	4.12M	2.52M	-2.47M	10.72M	3.74M
Cash Flow
Free Cash Flow	-9.74M	-8.40M	-8.60M	-12.66M	-11.75M	-11.46M
Operating Cash Flow	-9.73M	-8.40M	-8.60M	-12.65M	-11.74M	-11.45M
Investing Cash Flow	-3.31K	0.00	0.00	-13.07K	-11.79K	-7.15K
Financing Cash Flow	5.41M	7.76M	3.66M	76.82K	19.06M	24.68M

Soligenix Technical Analysis

• Technical Analysis Sentiment: Negative
• Last Price: 1.44
• 50DMA: Negative
• 100DMA: Negative
• 200DMA: Negative
• MACD: Negative
• RSI: Neutral
• STOCH: Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SNGX, the sentiment is Negative. The current price of 1.44 is above the 20-day moving average (MA) of 1.38, above the 50-day MA of 1.43, and below the 200-day MA of 1.87, indicating a neutral trend. The MACD of -0.02 indicates Negative momentum. The RSI at 46.65 is Neutral, neither overbought nor oversold. The STOCH value of 32.64 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for SNGX.

Soligenix Peers Comparison

Name	Overall Rating	Market Cap	P/E Ratio	ROE	Dividend Yield	Revenue Growth	EPS Growth
ATHA	55 Neutral	$25.95M	-0.68	-89.42%	―	―	66.10%
Sector *	51 Neutral	$7.86B	-0.30	-43.30%	2.27%	22.53%	-2.21%
BLRX	48 Neutral	$12.41M	-2.10	-22.03%	―	-41.76%	87.36%
AIMD	45 Neutral	$13.38M	-0.46	-106.58%	―	178.19%	68.57%
GOVX	44 Neutral	$4.95M	-0.06	-377.44%	―	8.52%	79.51%
SNGX	43 Neutral	$13.92M	―	-169.32%	―	―	53.13%
CANF	41 Neutral	$5.61M	―	―	―	―	―

Soligenix Corporate Events

Soligenix Regains Nasdaq Compliance as of November 2025

Soligenix, Inc. reported that on November 18, 2025, it received confirmation from Nasdaq that it had regained compliance with the minimum stockholders’ equity requirement necessary for continued listing on The Nasdaq Capital Market. This follows a previous notice from Nasdaq on August 15, 2025, indicating non-compliance. The company had reported stockholders’ equity of $7,597,976 in its quarterly report, surpassing the required $2,500,000, thus resolving the issue and closing the matter.

The most recent analyst rating on (SNGX) stock is a Buy with a $6.00 price target. To see the full list of analyst forecasts on Soligenix stock, see the SNGX Stock Forecast page.