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Bioline RX Ltd Sponsored ADR (BLRX)
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Bioline RX Ltd Sponsored ADR (BLRX) AI Stock Analysis

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BLRX

Bioline RX Ltd Sponsored ADR

(NASDAQ:BLRX)

Rating:48Neutral
Price Target:
$4.00
▲(6.10% Upside)
BioLine RX Ltd's stock score is primarily influenced by its financial performance and earnings call insights. Significant revenue growth and positive developments in clinical trials enhance the outlook, despite ongoing profitability and leverage challenges. Technical analysis indicates a bearish trend, and valuation metrics are less favorable due to negative earnings. The earnings call provided a more optimistic view with strategic achievements and financial efficiency improvements.
Positive Factors
Clinical Trial Results
Favorable results from the use of motixafortide in a therapeutic combination in pancreatic cancer increase the likelihood that BLRX will find a development partner.
Financial Stability
APHEXDA will provide a steady stream of royalties that support earlier stage development of assets expected to be in-licensed, most likely in oncology and/or rare disease spaces.
Negative Factors
Adverse Events
The most common Grade ≥ III adverse events in the trial were anemia and rash, which could impact patient outcomes.
Financial Performance
BioLineRx announced 2Q25 financial results, posting EPS of ($1.00) vs. the estimate of ($0.35), primarily due to warrant accounting adjustments.

Bioline RX Ltd Sponsored ADR (BLRX) vs. SPDR S&P 500 ETF (SPY)

Bioline RX Ltd Sponsored ADR Business Overview & Revenue Model

Company DescriptionBioline RX Ltd Sponsored ADR (BLRX) is a biotechnology company focused on the development of innovative therapies for the treatment of cancer and other serious diseases. The company operates primarily in the biopharmaceutical sector, leveraging its proprietary technologies to create novel drug candidates. Bioline RX is engaged in the research, development, and commercialization of its product pipeline, which includes therapeutics targeting various cancer indications and immune-related disorders.
How the Company Makes MoneyBioline RX generates revenue primarily through the development and commercialization of its therapeutic products. The company may receive revenue from milestone payments associated with partnerships and collaborations with larger pharmaceutical companies, as well as potential royalties from product sales once they are commercialized. Additionally, Bioline RX may engage in research agreements or licensing deals that provide upfront payments and future earnings based on the success of their drug candidates. Significant partnerships with established healthcare companies can also contribute to the company’s financial growth, especially if these collaborations lead to successful clinical trials and subsequent market approvals.

Bioline RX Ltd Sponsored ADR Earnings Call Summary

Earnings Call Date:Aug 14, 2025
(Q1-2025)
|
% Change Since: -4.31%|
Next Earnings Date:Dec 01, 2025
Earnings Call Sentiment Positive
The earnings call reflected a positive outlook with significant achievements in licensing agreements, financial efficiency, and promising clinical trial results in pancreatic cancer. However, there were challenges in revenue generation due to the transition of APHEXDA sales and ongoing efforts to acquire new assets without a definitive outcome yet.
Q1-2025 Updates
Positive Updates
Transformational Licensing Agreement with Ayrmid Pharma
Exclusive out-licensing agreement for APHEXDA with Ayrmid Pharma Limited, including upfront payment, significant commercial milestones, and royalties.
Significant Reduction in Operating Cash Burn
Reduced ongoing operating cash burn by over 70% from $40 million to less than $12 million annually.
Positive Financial Position
Net income of $5.1 million for Q1 2025, compared to a net loss of $0.7 million in Q1 2024, primarily due to non-operating income from the revaluation of warrants.
Strong Performance in Pancreatic Cancer Studies
Promising results from CheMo4METPANC trial, including a partial response rate of 64% and a disease control rate of 91%, with some patients showing significant long-term progression-free survival.
Encouraging APHEXDA Sales Under Ayrmid
APHEXDA sales generated $1.4 million in Q1 2025, resulting in $0.3 million of royalty revenues to BioLineRx.
Robust Cash Position
Ended Q1 2025 with $26.4 million in cash, cash equivalents, and short-term bank deposits, with a cash runway projected through the second half of 2026.
Negative Updates
Decrease in Total Revenues
Total revenues for Q1 2025 were $0.3 million, compared to $6.9 million in Q1 2024, primarily due to the transition of APHEXDA sales to Ayrmid.
Challenges in Sickle Cell Disease Treatment
Stem cell mobilization remains a challenge for sickle cell disease patients, with ongoing trials still in early phases.
Uncertainty in New Asset Acquisition
Ongoing search and evaluation of new assets in oncology and rare diseases, but no definitive announcements yet.
Company Guidance
During BioLineRx's Q1 2025 financial results call, the company highlighted several key metrics and strategic moves. The partnership with Ayrmid Pharma Limited, which started in 2024, resulted in $1.4 million in APHEXDA sales for Q1 2025, generating $0.3 million in royalty revenue for BioLineRx. The company's financials showed a significant reduction in operating expenses, with operating cash burn reduced by over 70% from $40 million to under $12 million annually, following a restructuring that included a headcount reduction and the shutdown of U.S. operations. BioLineRx ended the quarter with $26.4 million in cash, with a runway expected to last through the second half of 2026. The call detailed ongoing clinical developments, including a Phase 2b study of motixafortide in pancreatic cancer, with a planned interim analysis in 2026. The company continues to evaluate potential in-licensing opportunities to expand its pipeline, leveraging expertise in oncology and rare diseases.

Bioline RX Ltd Sponsored ADR Financial Statement Overview

Summary
BioLine RX Ltd shows significant revenue growth and improved EBITDA margin, indicating operational efficiency. However, the company still faces challenges with negative net income, high leverage, and weak cash flow from operations, which impact financial stability.
Income Statement
25
Negative
The company has shown significant revenue growth from 2023 to 2024, with a surge from $4.8 million to $28.94 million. However, the net profit margin remains negative, indicating ongoing profitability challenges. The negative EBIT margin highlights persistent operating losses, though the transition from a negative to a positive EBITDA margin suggests some improvement in operational efficiency.
Balance Sheet
40
Negative
The debt-to-equity ratio is relatively high at 1.12, indicating a heavy reliance on debt financing which could pose risks in terms of financial stability. The equity ratio has decreased, reflecting a reduced capacity to cover assets with equity. Despite these challenges, the company maintains a positive stockholders’ equity, indicating some level of financial health.
Cash Flow
30
Negative
The free cash flow remains negative, although there is a notable increase in financing inflows, reflecting the company's ability to raise funds. However, the operating cash flow to net income ratio is negative, suggesting that cash generation from operations is weak, which could impact long-term sustainability.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue28.94M4.80M0.000.000.00
Gross Profit19.68M1.11M0.000.000.00
EBITDA3.92M-57.09M-28.50M-24.07M-27.59M
Net Income-9.22M-60.61M-24.95M-27.05M-30.02M
Balance Sheet
Total Assets38.91M63.92M76.38M81.39M47.29M
Cash, Cash Equivalents and Short-Term Investments19.56M42.99M51.08M57.13M22.59M
Total Debt15.04M11.59M12.32M4.65M7.68M
Total Liabilities25.45M50.70M25.54M13.30M25.26M
Stockholders Equity13.46M13.22M50.84M68.09M22.03M
Cash Flow
Free Cash Flow-43.93M-22.91M-26.56M-23.67M-23.21M
Operating Cash Flow-43.87M-22.61M-26.24M-23.57M-23.21M
Investing Cash Flow29.37M1.44M4.01M-38.22M16.67M
Financing Cash Flow20.66M15.06M20.44M57.75M17.87M

Bioline RX Ltd Sponsored ADR Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3.77
Price Trends
50DMA
4.44
Negative
100DMA
3.85
Negative
200DMA
6.01
Negative
Market Momentum
MACD
-0.19
Positive
RSI
39.17
Neutral
STOCH
55.80
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BLRX, the sentiment is Negative. The current price of 3.77 is below the 20-day moving average (MA) of 4.00, below the 50-day MA of 4.44, and below the 200-day MA of 6.01, indicating a bearish trend. The MACD of -0.19 indicates Positive momentum. The RSI at 39.17 is Neutral, neither overbought nor oversold. The STOCH value of 55.80 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for BLRX.

Bioline RX Ltd Sponsored ADR Risk Analysis

Bioline RX Ltd Sponsored ADR disclosed 43 risk factors in its most recent earnings report. Bioline RX Ltd Sponsored ADR reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Bioline RX Ltd Sponsored ADR Peers Comparison

Overall Rating
UnderperformOutperform
Sector (60)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
60
Neutral
HK$18.32B5.55-4.00%3.32%9.92%-18.97%
48
Neutral
$15.89M-20.03%91.68%90.86%
45
Neutral
$16.96M11.60-7.30%-100.00%98.69%
44
Neutral
$19.62M-503.80%60.64%
44
Neutral
$17.50M-88.27%32.57%
38
Underperform
$22.29M-53.42%18.73%
33
Underperform
$16.93M-112.99%52.66%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BLRX
Bioline RX Ltd Sponsored ADR
3.71
-25.83
-87.44%
SYBX
Synlogic
1.45
0.01
0.69%
MBRX
Moleculin Biotech
0.68
-1.76
-72.13%
CTXR
Citius Pharmaceuticals
1.33
-13.75
-91.18%
CMMB
Chemomab Therapeutics
0.93
-0.18
-16.22%
PASG
Passage Bio
6.95
-8.31
-54.46%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 26, 2025