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Bioline RX Ltd Sponsored ADR (BLRX)
NASDAQ:BLRX
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Bioline RX Ltd Sponsored ADR (BLRX) AI Stock Analysis

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BLRX

Bioline RX Ltd Sponsored ADR

(NASDAQ:BLRX)

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Neutral 48 (OpenAI - 4o)
Rating:48Neutral
Price Target:
$3.50
▲(4.79% Upside)
BioLine RX Ltd's overall stock score reflects significant revenue growth and strategic initiatives, but is weighed down by ongoing profitability challenges and a bearish technical outlook. The company's strong cash position and potential in innovative treatments are promising, yet current revenue generation and market penetration remain hurdles.
Positive Factors
Joint Venture with Hemispherian
The JV with Hemispherian expands BioLineRx's pipeline into high-need cancer indications, enhancing its market position and potential revenue streams.
Strong Cash Position
A robust cash position supports operational stability and strategic investments, ensuring the company can sustain its R&D efforts into 2027.
USPTO Patent Allowance for GLIX1
The patent allowance for GLIX1 strengthens BioLineRx's IP portfolio, securing competitive advantage and supporting long-term growth in oncology.
Negative Factors
Minimal Revenue Generation
Low revenue generation indicates slow market penetration, which could hinder the company's ability to fund future growth and R&D initiatives.
High Leverage
High leverage increases financial risk, potentially limiting the company's flexibility to invest in new opportunities or weather economic downturns.
Negative Cash Flow from Operations
Negative cash flow from operations suggests weak cash generation, which could impact long-term sustainability and the ability to fund ongoing projects.

Bioline RX Ltd Sponsored ADR (BLRX) vs. SPDR S&P 500 ETF (SPY)

Bioline RX Ltd Sponsored ADR Business Overview & Revenue Model

Company DescriptionBioLineRx Ltd., a clinical-stage biopharmaceutical development company, focuses on oncology. The company develops Motixafortide, a peptide, which has completed Phase 3 clinical trials for the treatment of autologous stem cell mobilization and Phase 2a clinical trials for the treatment of pancreatic cancer; and that is in Phase 2 clinical trials for the treatment of metastatic pancreatic adenocarcinoma patients, and Phase 1b clinical trials in patients with acute respiratory distress syndrome secondary to COVID-19 and other respiratory viral infections, as well as for the treatment of solid tumors and acute myeloid leukemia. It is also developing AGI-134, an immuno-oncology agent, which is in Phase 1/2a clinical trials for the treatment of solid tumors; and BL-5010, a customized, proprietary, pen-like applicator for the non-surgical removal of skin lesions. The company has collaboration agreement with MSD for the cancer immunotherapy field; MD Anderson Cancer Center to investigate the combination of Motixafortide with KEYTRUDA (pembrolizumab) in pancreatic cancer; and licensing arrangement with Perrigo Company plc for over-the-counter sale of BL-5010. BioLineRx Ltd. was incorporated in 2003 and is headquartered in Hevel Modi'in, Israel.
How the Company Makes MoneyBioline RX generates revenue primarily through the development and commercialization of its therapeutic products. The company may receive revenue from milestone payments associated with partnerships and collaborations with larger pharmaceutical companies, as well as potential royalties from product sales once they are commercialized. Additionally, Bioline RX may engage in research agreements or licensing deals that provide upfront payments and future earnings based on the success of their drug candidates. Significant partnerships with established healthcare companies can also contribute to the company’s financial growth, especially if these collaborations lead to successful clinical trials and subsequent market approvals.

Bioline RX Ltd Sponsored ADR Earnings Call Summary

Earnings Call Date:Nov 24, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 12, 2026
Earnings Call Sentiment Neutral
The earnings call presented a mix of positive developments in R&D ventures and strong financial management, offset by minimal revenue growth and reduced operational expenses. The company's strategic focus on innovative treatments and a solid cash position are promising, but current revenue generation and market penetration remain challenges.
Q3-2025 Updates
Positive Updates
Joint Venture with Hemispherian
BioLineRx established a JV with Hemispherian to develop GLIX1 for glioblastoma and other cancers, combining expertise in cancer drug discovery and regulatory success.
FDA Clearance for GLIX1
The FDA cleared Hemispherian's IND for GLIX1, with plans to initiate a Phase I/IIa trial for glioblastoma in Q1 2026.
Strong Cash Position
BioLineRx ended Q3 2025 with $25.2 million in cash and equivalents, sufficient to fund operations into the first half of 2027.
Positive Interim Results for Sickle Cell Disease
An investigator-initiated trial showed positive results for motixafortide in sickle cell disease, with a presentation planned at the ASH Annual Meeting.
Reduction in Net Loss
Q3 2025 net loss was $1 million, compared to $5.8 million in Q3 2024, primarily due to reduced expenses following the Ayrmid out-licensing transaction.
Negative Updates
Minimal Revenue Generation
Q3 2025 revenues were only $0.4 million, reflecting royalties from APHEXDA sales, indicating slow market penetration.
Decreased R&D and Marketing Expenses
R&D expenses decreased to $1.7 million from $2.6 million in Q3 2024, and there were no sales and marketing expenses, reflecting reduced operational activity.
Company Guidance
During the BioLineRx Third Quarter 2025 Financial Results Conference Call, significant guidance was provided regarding the future direction and strategic initiatives of the company. A key highlight was the establishment of a joint venture (JV) with Hemispherian to develop GLIX1, a first-in-class oral molecule targeting glioblastoma with an FDA-cleared IND, aiming to initiate a Phase I/IIa trial in early 2026. The JV agreement grants Hemispherian a 60% stake, while BioLineRx holds 40%, with plans to increase its stake to 70% as it invests further. The company reported Q3 revenues of $0.4 million from APHEXDA royalties and a net loss of $1 million, with cash reserves of $25.2 million expected to support operations into the first half of 2027. BioLineRx is optimistic about GLIX1's potential across various cancer indications, supported by a robust patent portfolio extending through at least 2040.

Bioline RX Ltd Sponsored ADR Financial Statement Overview

Summary
BioLine RX Ltd shows significant revenue growth, but faces challenges with negative net income and high leverage. The company's ability to raise funds is positive, yet cash flow from operations remains weak, impacting long-term sustainability.
Income Statement
25
Negative
The company has shown significant revenue growth from 2023 to 2024, with a surge from $4.8 million to $28.94 million. However, the net profit margin remains negative, indicating ongoing profitability challenges. The negative EBIT margin highlights persistent operating losses, though the transition from a negative to a positive EBITDA margin suggests some improvement in operational efficiency.
Balance Sheet
40
Negative
The debt-to-equity ratio is relatively high at 1.12, indicating a heavy reliance on debt financing which could pose risks in terms of financial stability. The equity ratio has decreased, reflecting a reduced capacity to cover assets with equity. Despite these challenges, the company maintains a positive stockholders’ equity, indicating some level of financial health.
Cash Flow
30
Negative
The free cash flow remains negative, although there is a notable increase in financing inflows, reflecting the company's ability to raise funds. However, the operating cash flow to net income ratio is negative, suggesting that cash generation from operations is weak, which could impact long-term sustainability.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue17.25M28.94M4.80M0.000.000.00
Gross Profit10.23M19.68M1.11M0.000.000.00
EBITDA1.97M3.92M-57.09M-28.50M-24.07M-27.59M
Net Income-7.82M-9.22M-60.61M-24.95M-27.05M-30.02M
Balance Sheet
Total Assets43.27M38.91M63.92M76.38M81.39M47.29M
Cash, Cash Equivalents and Short-Term Investments28.16M19.56M42.99M51.08M57.13M22.59M
Total Debt12.60M15.04M11.59M12.32M4.65M7.68M
Total Liabilities23.20M25.45M50.70M25.54M13.30M25.26M
Stockholders Equity20.07M13.46M13.22M50.84M68.09M22.03M
Cash Flow
Free Cash Flow-21.20M-43.93M-22.91M-26.56M-23.67M-23.21M
Operating Cash Flow-21.20M-43.87M-22.61M-26.24M-23.57M-23.21M
Investing Cash Flow9.45M29.37M1.44M4.01M-38.22M16.67M
Financing Cash Flow8.72M20.66M15.06M20.44M57.75M17.87M

Bioline RX Ltd Sponsored ADR Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3.34
Price Trends
50DMA
3.64
Negative
100DMA
3.79
Negative
200DMA
3.73
Negative
Market Momentum
MACD
-0.07
Negative
RSI
41.47
Neutral
STOCH
28.99
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BLRX, the sentiment is Negative. The current price of 3.34 is below the 20-day moving average (MA) of 3.37, below the 50-day MA of 3.64, and below the 200-day MA of 3.73, indicating a bearish trend. The MACD of -0.07 indicates Negative momentum. The RSI at 41.47 is Neutral, neither overbought nor oversold. The STOCH value of 28.99 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for BLRX.

Bioline RX Ltd Sponsored ADR Risk Analysis

Bioline RX Ltd Sponsored ADR disclosed 43 risk factors in its most recent earnings report. Bioline RX Ltd Sponsored ADR reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Bioline RX Ltd Sponsored ADR Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$15.14M-22.03%-41.76%87.36%
45
Neutral
$16.61M-5.35-27.54%-100.00%93.62%
44
Neutral
$24.59M-0.1179.31%
44
Neutral
$24.14M-87.18%38.42%
38
Underperform
$23.27M-53.42%18.73%
33
Underperform
$13.81M-1.09-73.63%53.19%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BLRX
Bioline RX Ltd Sponsored ADR
3.20
-7.60
-70.37%
SYBX
Synlogic
1.42
0.01
0.71%
MBRX
Moleculin Biotech
6.63
-56.12
-89.43%
CTXR
Citius Pharmaceuticals
1.26
-2.38
-65.38%
CMMB
Chemomab Therapeutics
2.53
-4.15
-62.13%
PASG
Passage Bio
8.03
-6.94
-46.36%

Bioline RX Ltd Sponsored ADR Corporate Events

BioLineRx and Hemispherian Launch Joint Venture to Develop GLIX1 for Glioblastoma
Sep 29, 2025

On September 29, 2025, BioLineRx Ltd. announced a joint venture with Hemispherian AS to develop GLIX1, an innovative oral small molecule targeting DNA damage response in glioblastoma and other tumors. The joint venture will see Hemispherian holding 60% of the shares, with BioLineRx holding 40%, potentially increasing to 70% with further investment. The venture aims to address the significant unmet need in glioblastoma treatment, a market expected to exceed $3.8 billion annually by 2030. The FDA has cleared an IND application for a Phase 1/2a study of GLIX1, anticipated to begin in Q1 2026, highlighting the potential impact on BioLineRx’s operations and market positioning.

BioLineRx Reports Q2 2025 Financials and Strategic Updates
Aug 14, 2025

On August 14, 2025, BioLineRx Ltd. announced its financial results for the second quarter of 2025, highlighting a strong cash position with a runway extended into the first half of 2027. The company is actively evaluating opportunities to expand its pipeline in oncology and rare diseases, with ongoing discussions with potential partners. Clinical trials, including the CheMo4METPANC Phase 2b trial for metastatic pancreatic cancer and studies on sickle cell disease, are progressing. Financially, the company reported $0.3 million in revenues for the quarter, primarily from royalties, and a net loss of $3.9 million. The company has significantly reduced its expenses following a transaction with Ayrmid in late 2024.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 25, 2025