Transformational Licensing Agreement with Ayrmid Pharma
BioLineRx executed an exclusive license agreement with Ayrmid Pharma Ltd. for motixafortide, generating $10 million in upfront payments and eligibility for $87 million in potential milestones, along with 18% to 23% sales royalties.
Significant Revenue Growth
Total revenues for 2024 were $28.9 million, a 502.1% increase from $4.8 million in 2023, driven by upfront payments and milestones from licensing agreements.
Operational Streamlining and Cost Reduction
BioLineRx reduced operating cash burn by approximately 70%, from over $40 million annually to about $12 million, following the shutdown of U.S. operations and headcount reduction in Israel.
Strong Financial Position
BioLineRx ended 2024 with $29 million in pro forma cash and a cash runway projected to fund operations through the second half of 2026.
Promising Clinical Developments in Sickle Cell Disease
Positive initial results from motixafortide trials in sickle cell disease, showing the potential to mobilize enough stem cells for gene therapies in fewer cycles.