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Dyne Therapeutics, Inc. (DYN)
NASDAQ:DYN
US Market
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Dyne Therapeutics (DYN) AI Stock Analysis

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DYN

Dyne Therapeutics

(NASDAQ:DYN)

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Neutral 51 (OpenAI - 5.2)
Rating:51Neutral
Price Target:
$20.00
▼(-2.01% Downside)
Action:Reiterated
Date:06/23/26
The score is primarily constrained by weak financial performance driven by no revenue, widening losses, and substantial cash burn, despite a low-debt balance sheet. Technicals are constructive with the stock trading above major moving averages and positive MACD. Corporate events add a modest positive tilt from trial execution progress and added financing flexibility, while valuation remains limited by negative earnings and no dividend support.
Positive Factors
Platform & focused neuromuscular pipeline
Dyne’s FORCE™ delivery platform is a durable competitive asset for therapies targeting muscle tissue. A platform that can enable multiple antisense or payload programs increases program optionality and long-term value capture across rare neuromuscular indications, reducing single-program binary risk.
Negative Factors
Severe cash burn
Persistent, growing negative operating and free cash flow indicate the company is consuming substantial cash to fund development. This structural burn forces repeated financing or drawdowns on facilities, increasing dilution or leverage risk and pressuring long-term financial sustainability absent product revenue.
Read all positive and negative factors
Positive Factors
Negative Factors
Platform & focused neuromuscular pipeline
Dyne’s FORCE™ delivery platform is a durable competitive asset for therapies targeting muscle tissue. A platform that can enable multiple antisense or payload programs increases program optionality and long-term value capture across rare neuromuscular indications, reducing single-program binary risk.
Read all positive factors

Dyne Therapeutics (DYN) vs. SPDR S&P 500 ETF (SPY)

Dyne Therapeutics Business Overview & Revenue Model

Company Description
Dyne Therapeutics, Inc. is a U.S.-based biotechnology firm focused on developing advanced treatments for genetically driven muscle disorders. Utilizing its proprietary FORCE platform, which is engineered to deliver disease-modifying therapeutics, ...
How the Company Makes Money
Dyne Therapeutics does not market approved products and therefore does not generate recurring product sales revenue; as a clinical-stage biotech, its ability to make money primarily depends on raising capital and monetizing its R&D assets. Revenue...

Dyne Therapeutics Financial Statement Overview

Summary
Financial profile is pressured by a pre-revenue model with widening losses (net loss ~-$446M in 2025 and ~-$452M TTM) and heavy, worsening cash burn (operating cash flow ~-$442M TTM; FCF ~-$462M TTM). The balance sheet is a relative positive with very low leverage (debt-to-equity ~0.02), but equity has declined and ROE is deeply negative, limiting the overall financial quality score.
Income Statement
12
Very Negative
Balance Sheet
64
Positive
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-1.07M-2.05M-2.24M-2.46M0.000.00
EBITDA-432.20M-437.97M-315.18M-233.48M-163.50M-148.20M
Net Income-451.71M-446.21M-317.42M-235.94M-168.10M-149.29M
Balance Sheet
Total Assets1.08B1.19B691.23M165.08M306.32M425.66M
Cash, Cash Equivalents and Short-Term Investments972.16M1.11B642.27M123.10M256.01M376.57M
Total Debt19.30M20.28M23.99M27.41M30.48M32.64M
Total Liabilities214.90M214.83M61.40M73.79M53.96M57.47M
Stockholders Equity865.05M972.13M629.84M91.29M252.36M368.20M
Cash Flow
Free Cash Flow-462.19M-405.13M-294.75M-188.89M-156.71M-123.18M
Operating Cash Flow-442.24M-403.21M-292.37M-188.16M-153.65M-119.56M
Investing Cash Flow-32.60M-28.75M-204.08M83.31M87.20M-137.89M
Financing Cash Flow756.13M890.31M809.89M54.32M37.39M157.82M

Dyne Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price20.41
Price Trends
50DMA
18.41
Positive
100DMA
17.87
Positive
200DMA
17.85
Positive
Market Momentum
MACD
0.71
Negative
RSI
63.69
Neutral
STOCH
76.60
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DYN, the sentiment is Positive. The current price of 20.41 is above the 20-day moving average (MA) of 18.80, above the 50-day MA of 18.41, and above the 200-day MA of 17.85, indicating a bullish trend. The MACD of 0.71 indicates Negative momentum. The RSI at 63.69 is Neutral, neither overbought nor oversold. The STOCH value of 76.60 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for DYN.

Dyne Therapeutics Risk Analysis

Dyne Therapeutics disclosed 83 risk factors in its most recent earnings report. Dyne Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Dyne Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
68
Neutral
$3.28B-1.41%95.29%98.21%
61
Neutral
$1.57B-81.25-4.83%23.64%-29.23%
54
Neutral
$1.78B27.454.89%-2.20%77.51%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$3.46B-6.60-58.28%10.17%
48
Neutral
$3.58B-54.61-5.89%157.97%86.11%
45
Neutral
$6.51B-12.58-83.29%0.01%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DYN
Dyne Therapeutics
21.26
11.74
123.32%
SRPT
Sarepta Therapeutics
17.02
-0.08
-0.47%
COGT
Cogent Biosciences
38.74
31.56
439.55%
ARQT
Arcutis Biotherapeutics
26.76
12.74
90.87%
BEAM
Beam Therapeutics
34.95
17.94
105.47%
IMCR
Immunocore Holdings
30.42
-0.96
-3.06%

Dyne Therapeutics Corporate Events

Executive/Board Changes
Dyne Therapeutics Names Barry Greene Independent Board Director
Positive
Jun 22, 2026
On June 22, 2026, Dyne Therapeutics, Inc. appointed Barry E. Greene as a Class I independent director to its board, with a term extending until the 2027 Annual Meeting of Stockholders and continuation subject to standard conditions such as death, ...
Business Operations and StrategyPrivate Placements and Financing
Dyne Therapeutics Expands Hercules Debt Facility for Flexibility
Positive
Jun 17, 2026
On June 16, 2026, Dyne Therapeutics entered into a second amendment to its loan and security agreement with Hercules Capital and other lenders, expanding its debt facility to up to $400 million and relaxing certain financial covenants. The amendme...
Business Operations and StrategyExecutive/Board ChangesRegulatory Filings and ComplianceShareholder Meetings
Dyne Therapeutics Expands Share Authorization After Stockholder Approvals
Positive
Jun 8, 2026
On June 5, 2026, Dyne Therapeutics, Inc. held its 2026 annual meeting of stockholders, where shareholders elected David Lubner, Brian Posner and Jason Rhodes as Class III directors for terms expiring at the 2029 annual meeting. Investors also appr...
Business Operations and StrategyProduct-Related Announcements
Dyne Fully Enrolls ACHIEVE Trial for DM1 Therapy
Positive
Jun 3, 2026
On June 3, 2026, Dyne Therapeutics announced it has fully enrolled 71 participants in the registrational expansion cohort of its global Phase 1/2 ACHIEVE trial of zeleciment basivarsen in myotonic dystrophy type 1. The trial, which selected a regi...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 23, 2026