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Dyne Therapeutics (DYN)
NASDAQ:DYN
US Market

Dyne Therapeutics (DYN) AI Stock Analysis

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DYN

Dyne Therapeutics

(NASDAQ:DYN)

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Neutral 56 (OpenAI - 5.2)
Rating:56Neutral
Price Target:
$17.50
▼(-3.63% Downside)
Action:ReiteratedDate:03/11/26
The score is primarily constrained by continued pre-revenue operations with widening losses and accelerating cash burn, despite a strong, low-leverage balance sheet. Technicals show an uptrend but with mixed momentum signals, while valuation support is limited due to a negative P/E and no dividend. Corporate updates are positive, citing encouraging clinical progress and significant cash runway.
Positive Factors
Targeted delivery platform (FORCE)
Dyne's FORCE platform is a structural competitive asset: durable targeted-delivery capability to muscle tissue can raise clinical success probabilities across multiple programs, enable platform-based pipeline expansion and partnerships, and create a technological moat that supports long-term commercial differentiation.
Negative Factors
Pre-revenue with widening losses
Persistent pre-revenue status with rapidly widening losses is a foundational risk: without product sales, the company must continuously fund R&D and operations externally. Ongoing negative profitability over multiple years pressures returns and heightens reliance on successful clinical outcomes and financing events.
Read all positive and negative factors
Positive Factors
Negative Factors
Targeted delivery platform (FORCE)
Dyne's FORCE platform is a structural competitive asset: durable targeted-delivery capability to muscle tissue can raise clinical success probabilities across multiple programs, enable platform-based pipeline expansion and partnerships, and create a technological moat that supports long-term commercial differentiation.
Read all positive factors

Dyne Therapeutics (DYN) vs. SPDR S&P 500 ETF (SPY)

Dyne Therapeutics Business Overview & Revenue Model

Company Description
Dyne Therapeutics, Inc., a muscle disease company, operates as a biotechnology company that focuses on advancing therapeutics for genetically driven muscle diseases in the United States. It develops various programs for myotonic dystrophy type 1, ...
How the Company Makes Money
As a clinical-stage biopharmaceutical company, Dyne’s revenue, when present, is primarily generated from collaborations and licensing arrangements (e.g., upfront payments, research funding, and potential development, regulatory, and sales-based mi...

Dyne Therapeutics Financial Statement Overview

Summary
Balance sheet strength and low leverage (debt-to-equity ~0.02; assets ~$1.19B) support near-term operations, but the company remains pre-revenue with sharply widening losses (net loss ~-$446M in 2025) and accelerating cash burn (operating cash flow ~-$403M; free cash flow ~-$405M in 2025), increasing longer-term funding risk.
Income Statement
12
Very Negative
Balance Sheet
66
Positive
Cash Flow
28
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit-2.05M-2.24M-2.46M0.000.00
EBITDA-437.97M-315.18M-233.48M-169.28M-148.94M
Net Income-446.21M-317.42M-235.94M-168.10M-149.29M
Balance Sheet
Total Assets1.19B691.23M165.08M306.32M425.66M
Cash, Cash Equivalents and Short-Term Investments1.11B642.27M123.10M256.01M376.57M
Total Debt20.28M23.99M27.41M30.48M32.64M
Total Liabilities214.83M61.40M73.79M53.96M57.47M
Stockholders Equity972.13M629.84M91.29M252.36M368.20M
Cash Flow
Free Cash Flow-405.13M-294.75M-188.89M-156.71M-123.18M
Operating Cash Flow-403.21M-292.37M-188.16M-153.65M-119.56M
Investing Cash Flow-28.75M-204.08M83.31M87.20M-137.89M
Financing Cash Flow890.31M809.89M54.32M37.39M157.82M

Dyne Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price18.16
Price Trends
50DMA
17.20
Positive
100DMA
18.27
Negative
200DMA
15.69
Positive
Market Momentum
MACD
0.32
Positive
RSI
52.80
Neutral
STOCH
65.29
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DYN, the sentiment is Positive. The current price of 18.16 is below the 20-day moving average (MA) of 18.26, above the 50-day MA of 17.20, and above the 200-day MA of 15.69, indicating a neutral trend. The MACD of 0.32 indicates Positive momentum. The RSI at 52.80 is Neutral, neither overbought nor oversold. The STOCH value of 65.29 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for DYN.

Dyne Therapeutics Risk Analysis

Dyne Therapeutics disclosed 83 risk factors in its most recent earnings report. Dyne Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Dyne Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
63
Neutral
$2.89B-228.91-10.26%129.21%80.35%
56
Neutral
$3.00B-5.63-61.45%-2.75%
54
Neutral
$2.49B-34.27-7.31%-84.07%-157.71%
53
Neutral
$2.42B-3.16-57.52%47.15%-311.26%
53
Neutral
$1.62B-19.61-6.93%27.51%38.72%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$5.78B-100.22%4.32%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DYN
Dyne Therapeutics
18.16
10.61
140.53%
SRPT
Sarepta Therapeutics
23.08
-32.57
-58.53%
COGT
Cogent Biosciences
35.62
31.16
698.65%
ARQT
Arcutis Biotherapeutics
23.27
8.70
59.71%
BEAM
Beam Therapeutics
24.49
8.12
49.60%
IMCR
Immunocore Holdings
31.96
5.84
22.36%

Dyne Therapeutics Corporate Events

Business Operations and StrategyFinancial Disclosures
Dyne Therapeutics Highlights Pipeline and Cash at JPM Conference
Positive
Jan 12, 2026
On January 12, 2026, Dyne Therapeutics released an investor presentation at the J.P. Morgan Healthcare Conference outlining its current operations, late-stage clinical pipeline and plans to advance its FORCE platform-based neuromuscular therapies ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 11, 2026