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Dynavax Technologies Corp. (DVAX)
NASDAQ:DVAX
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Dynavax (DVAX) AI Stock Analysis

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DVAX

Dynavax

(NASDAQ:DVAX)

Rating:52Neutral
Price Target:
$10.50
▼(-2.96% Downside)
The overall stock score of 52 reflects a mixed outlook. The positive sentiment from the earnings call, with record revenue and market share growth, is offset by financial performance challenges, including revenue contraction and net losses. Technical analysis and valuation also present concerns, with bearish momentum and a negative P/E ratio.
Positive Factors
Analyst Rating
Analyst's recommendation remains 'Outperform', indicating confidence in the company's growth potential.
Earnings Performance
Second-quarter Heplisav sales of $92 million surpassed estimates, indicating a 31% year-over-year growth.
Guidance and Forecast
Dynavax raised the lower end of FY25 Heplisav revenue guidance, demonstrating confidence in future performance.
Market Share Growth
Heplisav's market share increased to 45%, reflecting strong market presence and potential for further revenue growth.
Negative Factors
Market Segment Performance
Market share in the prioritized IDN/clinic market segment showed a slight reduction at 51%.
Sales Estimates
First-quarter Heplisav sales came in below estimates, reflecting a miss on expectations.

Dynavax (DVAX) vs. SPDR S&P 500 ETF (SPY)

Dynavax Business Overview & Revenue Model

Company DescriptionDynavax Technologies Corporation is a biopharmaceutical company focused on developing and commercializing innovative vaccines and immunotherapies. The company is primarily engaged in the research and development of its proprietary toll-like receptor (TLR) platform, which is aimed at enhancing the immune response to infections and diseases. Dynavax's core product is HEPLISAV-B, a hepatitis B vaccine that has received regulatory approvals in various markets, including the United States. The company operates in the biotechnology sector and is dedicated to addressing unmet medical needs through its advanced therapeutic solutions.
How the Company Makes MoneyDynavax generates revenue primarily through the sales of its products, particularly HEPLISAV-B, which has been established as a key revenue stream following its approval and commercialization. The company also engages in collaborations and partnerships with other pharmaceutical companies, which may involve upfront payments, milestone payments, and royalties on future sales of products developed through these collaborations. These strategic partnerships help to bolster Dynavax's financial performance and can provide additional funding for its research and development activities.

Dynavax Earnings Call Summary

Earnings Call Date:Aug 07, 2025
(Q2-2025)
|
% Change Since: -2.17%|
Next Earnings Date:Oct 30, 2025
Earnings Call Sentiment Positive
The earnings call reflects a strong positive sentiment, with significant revenue growth, increased market share, and successful financial performance. Although there were some increases in expenses and a decrease in cash position due to strategic decisions, the overall outlook remains optimistic with updated revenue guidance and progress in clinical pipeline programs.
Q2-2025 Updates
Positive Updates
Record Revenue for HEPLISAV-B
Dynavax reported $92 million in Q2 net product revenue for HEPLISAV-B, marking an increase of 31% year-over-year.
Increased Market Share
HEPLISAV-B's estimated market share grew to 45% in the U.S. adult hepatitis B vaccine market, up from 42% in the prior year quarter.
Updated Revenue Guidance
Full-year 2025 HEPLISAV-B net product revenue guidance increased to $315 million to $325 million, with the low end raised from $305 million.
Clinical Pipeline Progress
Key milestones achieved in vaccine development programs, including the shingles vaccine program and new programs in pandemic influenza and Lyme disease.
Strong Financial Performance
Achieved GAAP net income of $19 million, up from $11 million in the second quarter of 2024, and non-GAAP adjusted EBITDA improved to $37 million from $20 million last year.
Successful Share Repurchase
Completed a $200 million share repurchase program, retiring over 16 million shares, which reflects effective capital allocation.
Negative Updates
Increased SG&A Expenses
Q2 SG&A expenses rose to $50 million from $42 million in the prior year, primarily due to a $13 million increase related to a proxy contest campaign.
Cash Position Decrease
Cash and marketable securities decreased from $714 million at the end of 2024 to $614 million, largely due to the share repurchase program.
Company Guidance
During the Dynavax Technologies Q2 2025 financial results call, the company reported a record revenue quarter for HEPLISAV-B with $92 million in net product revenue, marking a 31% increase year-over-year. The firm's market share in the U.S. adult hepatitis B vaccine market rose to 45% in Q2, up from 42% the previous year, aligning with their goal of achieving 60% by 2030. Dynavax updated its full-year 2025 HEPLISAV-B revenue guidance to $315-$325 million, raising the lower end from $305 million. The company highlighted progress in its vaccine pipeline, including upcoming Phase I/II trial data for its novel shingles program and advancements in pandemic influenza and Lyme disease programs. HEPLISAV-B's growth was driven by increased awareness and higher vaccination rates, especially in the retail segment, which grew by 35% and is expected to comprise at least 50% of the hepatitis B market by 2030. Dynavax reported a 29% year-over-year increase in total revenues to $95 million and improved gross margins to 85%. The company concluded a $200 million share repurchase program, retiring over 16 million shares, and maintained a strong cash position of $614 million at the end of Q2 2025.

Dynavax Financial Statement Overview

Summary
Dynavax is facing significant revenue contraction and net losses, negatively impacting its income statement. The balance sheet shows moderate strength with reasonable leverage, but decreased equity and rising debt are concerning. Cash flow management is adequate, though operational challenges persist.
Income Statement
40
Negative
The income statement shows declining revenue from the previous fiscal year, with a TTM revenue of $294.6M compared to the previous annual revenue of $722.7M. Gross profit margin for the TTM is approximately 82.3%, indicating strong product profitability. However, the net profit margin is negative, at -20.4%, due to a net loss of $60.1M. This reflects challenges in cost management and achieving profitability.
Balance Sheet
50
Neutral
The balance sheet is moderately strong, with a debt-to-equity ratio of 0.54, suggesting a balanced use of leverage. The equity ratio stands at 56.1%, highlighting a solid equity base. However, the decline in stockholders' equity and rising total debt indicate potential financial stress.
Cash Flow
55
Neutral
Cash flow analysis reveals a positive operating cash flow of $63.6M in the TTM, but free cash flow has decreased compared to the previous year. The operating cash flow to net income ratio is negative, reflecting operational inefficiencies. The free cash flow to net income ratio is positive, suggesting better cash flow management despite net losses.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue316.27M277.25M232.28M722.68M439.44M46.55M
Gross Profit261.97M227.80M182.12M460.53M265.87M32.64M
EBITDA-34.56M45.70M9.67M307.70M95.71M-46.84M
Net Income-52.73M27.31M-6.39M293.16M76.71M-75.24M
Balance Sheet
Total Assets918.45M986.26M997.10M985.85M1.04B353.27M
Cash, Cash Equivalents and Short-Term Investments613.73M713.83M742.30M624.39M545.95M165.04M
Total Debt285.50M254.42M256.91M258.01M257.38M217.85M
Total Liabilities424.29M389.46M375.02M404.84M816.87M294.58M
Stockholders Equity494.16M596.80M622.07M581.01M222.37M58.69M
Cash Flow
Free Cash Flow66.07M60.16M96.46M55.58M326.05M-103.32M
Operating Cash Flow76.27M66.51M100.56M62.72M335.53M-92.25M
Investing Cash Flow109.60M-18.04M-153.93M-316.00M14.22M-26.53M
Financing Cash Flow-200.20M-102.02M1.39M19.52M55.78M109.50M

Dynavax Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price10.82
Price Trends
50DMA
10.53
Positive
100DMA
10.84
Negative
200DMA
11.86
Negative
Market Momentum
MACD
0.03
Positive
RSI
50.59
Neutral
STOCH
35.00
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DVAX, the sentiment is Neutral. The current price of 10.82 is below the 20-day moving average (MA) of 10.98, above the 50-day MA of 10.53, and below the 200-day MA of 11.86, indicating a neutral trend. The MACD of 0.03 indicates Positive momentum. The RSI at 50.59 is Neutral, neither overbought nor oversold. The STOCH value of 35.00 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for DVAX.

Dynavax Risk Analysis

Dynavax disclosed 50 risk factors in its most recent earnings report. Dynavax reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Dynavax Peers Comparison

Overall Rating
UnderperformOutperform
Sector (65)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
75
Outperform
$1.92B-2.82%38.68%-160.14%
74
Outperform
$1.41B11.3618.32%1.37%-18.10%
65
Neutral
$2.31B36.046.38%5.55%1145.24%
65
Neutral
¥341.96B11.05-0.16%2.40%9.83%-10.32%
59
Neutral
$1.11B-15.57%2.25%-301.59%
52
Neutral
$1.24B64.45-9.28%26.66%-419.55%
47
Neutral
$1.36B-20.41%0.45%-125.61%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DVAX
Dynavax
10.82
-0.45
-3.99%
PCRX
Pacira Pharmaceuticals
25.04
12.57
100.80%
SUPN
Supernus Pharmaceuticals
42.64
9.37
28.16%
ANIP
ANI Pharmaceuticals
88.74
29.54
49.90%
AMPH
Amphastar Pharmaceuticals
30.48
-11.96
-28.18%
EVO
Evotec AG
3.81
0.50
15.11%

Dynavax Corporate Events

Executive/Board ChangesShareholder Meetings
Dynavax Elects Directors and Approves Key Amendments
Neutral
Jun 17, 2025

On April 14, 2025, Dynavax held its Annual Meeting where stockholders elected four Class I directors to serve until the 2028 meeting. The meeting also saw the approval of executive compensation, the ratification of Ernst & Young LLP as the independent auditor, and the amendment of the Certificate of Incorporation to declassify the Board. However, a stockholder proposal to amend the bylaws without stockholder approval was not passed.

The most recent analyst rating on (DVAX) stock is a Buy with a $31.00 price target. To see the full list of analyst forecasts on Dynavax stock, see the DVAX Stock Forecast page.

Executive/Board Changes
Dynavax Appoints New Chief Accounting Officer
Neutral
May 13, 2025

On May 8, 2025, Dynavax Technologies Corporation announced the appointment of Joseph Metzinger as Vice President and Chief Accounting Officer, effective May 12, 2025. Metzinger, a seasoned financial executive with 19 years of experience, has been consulting for Dynavax since 2024 and previously held senior roles at CFGI and ACC Consumer Finance. His appointment includes a base salary, performance bonus, and stock options, with no familial or transactional ties to current executives.

The most recent analyst rating on (DVAX) stock is a Buy with a $29.00 price target. To see the full list of analyst forecasts on Dynavax stock, see the DVAX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 11, 2025