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Dynavax Technologies Corp. (DVAX)
NASDAQ:DVAX
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Dynavax (DVAX) AI Stock Analysis

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DVAX

Dynavax

(NASDAQ:DVAX)

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Neutral 58 (OpenAI - 4o)
Rating:58Neutral
Price Target:
$10.50
▼(-3.05% Downside)
Dynavax's overall stock score reflects a mixed financial performance with profitability challenges, offset by positive technical indicators and a strong earnings call. The strategic initiatives and revenue growth are promising, but valuation concerns and profitability issues weigh on the score.
Positive Factors
Revenue Growth
The consistent revenue growth from HEPLISAV-B indicates strong market demand and solidifies Dynavax's position in the hepatitis B vaccine market.
Strategic Partnerships
The partnership with Vaxart for an oral COVID-19 vaccine could diversify Dynavax's product offerings and enhance its competitive position in the vaccine market.
Pipeline Progress
Advancements in the shingles vaccine program demonstrate Dynavax's commitment to expanding its product pipeline, potentially leading to new revenue streams.
Negative Factors
Profitability Challenges
Persistent profitability issues could hinder Dynavax's ability to reinvest in growth and limit its financial flexibility over the long term.
Cash Position Decrease
The decrease in cash reserves, partly due to share repurchases, may constrain Dynavax's ability to fund future growth initiatives and operations.
Seasonality Impact
Seasonal demand fluctuations could impact revenue consistency, affecting financial performance predictability and planning.

Dynavax (DVAX) vs. SPDR S&P 500 ETF (SPY)

Dynavax Business Overview & Revenue Model

Company DescriptionDynavax Technologies Corporation is a biopharmaceutical company focused on developing and commercializing innovative vaccines and immunotherapies. The company is primarily engaged in the research and development of its proprietary toll-like receptor (TLR) platform, which is aimed at enhancing the immune response to infections and diseases. Dynavax's core product is HEPLISAV-B, a hepatitis B vaccine that has received regulatory approvals in various markets, including the United States. The company operates in the biotechnology sector and is dedicated to addressing unmet medical needs through its advanced therapeutic solutions.
How the Company Makes MoneyDynavax generates revenue primarily through the sales of its products, particularly HEPLISAV-B, which has been established as a key revenue stream following its approval and commercialization. The company also engages in collaborations and partnerships with other pharmaceutical companies, which may involve upfront payments, milestone payments, and royalties on future sales of products developed through these collaborations. These strategic partnerships help to bolster Dynavax's financial performance and can provide additional funding for its research and development activities.

Dynavax Earnings Call Summary

Earnings Call Date:Oct 24, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Feb 19, 2026
Earnings Call Sentiment Positive
The earnings call highlighted strong revenue growth and strategic advancements in the company's pipeline and partnerships, notably with Vaxart. Despite a few concerns about potential seasonal impacts and a decrease in cash reserves, the company's overall financial health and strategic initiatives suggest a positive outlook.
Q3-2025 Updates
Positive Updates
HEPLISAV-B Revenue Growth
HEPLISAV-B generated approximately $90 million in net product revenue this quarter, representing a 13% increase year-over-year. The U.S. adult hepatitis B vaccine market share reached 46%, up from 44% in the prior year period.
Shingles Vaccine Program Progress
Progress was made in the shingles vaccine program with the initiation of Part 2 of the Phase I/II study in adults aged 70 years and older. Top line immunogenicity and safety results are expected in the second half of 2026.
Strategic Deal with Vaxart
Dynavax executed a strategic deal to access a Phase IIb COVID-19 oral vaccine candidate from Vaxart. The program has enrolled over 5,400 subjects in a Phase IIb safety and efficacy study.
Share Repurchase Program
Authorization of a new $100 million share repurchase plan, reflecting confidence in the company's long-term growth and commitment to enhancing shareholder value.
Financial Performance
GAAP net income of $27 million for the third quarter of 2025, compared to $18 million in the third quarter of 2024. Non-GAAP adjusted EBITDA improved to $36 million, up from $25 million last year.
Negative Updates
Seasonality Impact on HEPLISAV-B
Expectation of some seasonality impact in Q4 due to the holidays, which may slow down demand despite strong retail performance.
Cash Position Decrease
Cash and equivalents decreased to $648 million from $714 million at the end of 2024, primarily due to the $200 million share repurchase program.
Company Guidance
During the Dynavax Technologies Third Quarter 2025 Financial Results Conference Call, the company provided comprehensive guidance emphasizing their strategic growth initiatives and financial projections. Key metrics highlighted included a 13% year-over-year increase in HEPLISAV-B net product revenue, reaching $90 million, and an expansion in U.S. adult hepatitis B vaccine market share to 46%. The company reiterated its goal of achieving at least 60% market share by 2030. Dynavax also discussed the progress of their clinical pipeline, including the shingles vaccine program's advancement into Part 2 of the Phase I/II study and a strategic license agreement with Vaxart for an oral COVID-19 vaccine. Financially, they reported a GAAP net income of $27 million, up from $18 million in the same period last year, and adjusted EBITDA of $36 million. Additionally, Dynavax announced a new $100 million share repurchase program, following the completion of a $200 million program, underlining their commitment to enhancing shareholder value while maintaining robust financial health with $648 million in cash and equivalents.

Dynavax Financial Statement Overview

Summary
Dynavax's financial performance is mixed. Revenue growth and strong gross profit margins are positive, but negative net income and EBIT margins indicate profitability challenges. The balance sheet shows improved leverage but negative returns on equity. Cash flow generation is improving, but profitability issues remain a concern.
Income Statement
45
Neutral
Dynavax's income statement shows mixed results. The company has experienced revenue growth in the TTM period, but profitability metrics such as net profit margin and EBIT margin are negative, indicating operational challenges. The gross profit margin remains strong, suggesting good cost management. However, the negative net income and declining EBIT margins are concerning for long-term profitability.
Balance Sheet
60
Neutral
The balance sheet reflects a moderate financial position. The debt-to-equity ratio has improved over time, indicating better leverage management. However, the return on equity is negative in the TTM period, highlighting profitability issues. The equity ratio is stable, suggesting a solid asset base relative to equity.
Cash Flow
55
Neutral
Cash flow analysis shows a positive trend in free cash flow growth, indicating improved cash generation capabilities. The operating cash flow to net income ratio is healthy, suggesting efficient cash conversion. However, the free cash flow to net income ratio indicates that cash flow is not fully translating into profitability, which could be a risk factor.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue330.51M277.25M232.28M722.68M439.44M46.55M
Gross Profit194.42M227.80M182.12M460.53M265.87M32.64M
EBITDA-36.86M45.70M9.67M307.70M95.71M-46.84M
Net Income-43.40M27.31M-6.39M293.16M76.71M-75.24M
Balance Sheet
Total Assets946.51M986.26M997.10M985.85M1.04B353.27M
Cash, Cash Equivalents and Short-Term Investments647.82M713.83M742.30M624.39M545.95M165.04M
Total Debt285.02M254.42M256.91M258.01M257.38M217.85M
Total Liabilities412.37M389.46M375.02M404.84M816.87M294.58M
Stockholders Equity534.14M596.80M622.07M581.01M222.37M58.69M
Cash Flow
Free Cash Flow80.54M60.16M96.46M55.58M326.05M-103.32M
Operating Cash Flow90.63M66.51M100.56M62.72M335.53M-92.25M
Investing Cash Flow152.39M-18.04M-153.93M-316.00M14.22M-26.53M
Financing Cash Flow-202.74M-102.02M1.39M19.52M55.78M109.50M

Dynavax Technical Analysis

Technical Analysis Sentiment
Positive
Last Price10.83
Price Trends
50DMA
10.02
Positive
100DMA
10.32
Positive
200DMA
11.11
Negative
Market Momentum
MACD
0.15
Negative
RSI
62.90
Neutral
STOCH
68.91
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DVAX, the sentiment is Positive. The current price of 10.83 is above the 20-day moving average (MA) of 10.23, above the 50-day MA of 10.02, and below the 200-day MA of 11.11, indicating a neutral trend. The MACD of 0.15 indicates Negative momentum. The RSI at 62.90 is Neutral, neither overbought nor oversold. The STOCH value of 68.91 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for DVAX.

Dynavax Risk Analysis

Dynavax disclosed 40 risk factors in its most recent earnings report. Dynavax reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Dynavax Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
74
Outperform
$1.13B9.0018.32%1.37%-18.10%
70
Outperform
$1.13B39.2522.96%26.34%-32.79%
62
Neutral
$1.96B-2.82%38.68%-160.14%
58
Neutral
$1.21B-7.14%26.73%-310.39%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$981.78M-15.57%2.25%-301.59%
44
Neutral
$1.19B-17.46%-1.19%5.06%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DVAX
Dynavax
10.83
-2.83
-20.72%
PCRX
Pacira Pharmaceuticals
22.05
4.55
26.00%
ANIP
ANI Pharmaceuticals
90.43
28.69
46.47%
AMPH
Amphastar Pharmaceuticals
24.03
-24.54
-50.53%
EVO
Evotec AG
3.08
-1.79
-36.76%
COLL
Collegium Pharmaceutical
42.30
10.12
31.45%

Dynavax Corporate Events

Dynavax Technologies Advances in Pneumonic Plague Vaccine Study
Oct 27, 2025

Dynavax Technologies is conducting a Phase 2 study titled ‘Immunogenicity, Safety, and Tolerability of rF1V-1018 Vaccine in Adults 18 to 55 Years of Age.’ The study aims to evaluate the effectiveness, safety, and tolerability of the rF1V-1018 vaccine, which is significant for preventing pneumonic plague caused by aerosol exposure to Yersinia pestis.

Executive/Board Changes
Dynavax Announces Management Restructuring Changes
Neutral
Oct 16, 2025

On October 15, 2025, Dynavax Technologies Corporation’s Board of Directors approved changes in its management structure. David F. Novack will transition from his roles as President and Chief Operating Officer to Senior Vice President and Chief Operating Officer, effective January 1, 2026. Additionally, Robert Janssen, M.D. will be removed from his roles as Chief Medical Officer and Senior Vice President, Clinical Development, Medical and Regulatory Affairs, with his employment concluding by March 2, 2026, as the company searches for a successor.

The most recent analyst rating on (DVAX) stock is a Hold with a $10.00 price target. To see the full list of analyst forecasts on Dynavax stock, see the DVAX Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Dynavax Announces Positive Results for Shingles Vaccine
Positive
Aug 21, 2025

On August 21, 2025, Dynavax announced positive topline results from Part 1 of its Phase 1/2 clinical trial for Z-1018, a novel shingles vaccine candidate. The trial showed that Z-1018 has comparable immune responses to Shingrix, with a favorable tolerability profile, marking a significant step in Dynavax’s efforts to disrupt the shingles vaccine market. Plans are underway to advance Z-1018 into Part 2 of the trial for adults aged 70 and older, aiming to further de-risk the program before Phase 3 development.

The most recent analyst rating on (DVAX) stock is a Hold with a $11.00 price target. To see the full list of analyst forecasts on Dynavax stock, see the DVAX Stock Forecast page.

Dynavax Technologies Reports Strong Q2 Earnings
Aug 12, 2025

Dynavax Technologies recently held its earnings call, which conveyed a strong positive sentiment. The company reported significant revenue growth, an increased market share, and successful financial performance. While there were some increases in expenses and a decrease in cash position due to strategic decisions, the overall outlook remains optimistic with updated revenue guidance and progress in clinical pipeline programs.

Dynavax Technologies Reports Strong Q2 2025 Results
Aug 8, 2025

Dynavax Technologies Corporation is a commercial-stage biopharmaceutical company focused on developing and commercializing innovative vaccines, primarily within the infectious disease sector, with a unique emphasis on utilizing its CpG 1018® adjuvant to enhance immune responses.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 06, 2025