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Dynavax Technologies Corp. (DVAX)
NASDAQ:DVAX
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Dynavax (DVAX) AI Stock Analysis

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DVAX

Dynavax

(NASDAQ:DVAX)

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Outperform 70 (OpenAI - 4o)
Rating:70Outperform
Price Target:
$12.50
▲(9.36% Upside)
Dynavax's strong earnings call and positive technical indicators are significant strengths, reflecting strategic growth and market momentum. However, profitability challenges and valuation concerns moderate the overall score.
Positive Factors
Revenue Growth
The consistent revenue growth of HEPLISAV-B indicates strong product demand and market penetration, supporting Dynavax's long-term revenue prospects.
Strategic Partnerships
The partnership with Vaxart enhances Dynavax's product pipeline, potentially expanding its market presence and diversifying revenue sources.
Shareholder Value
The share repurchase program underscores management's confidence in Dynavax's financial health and commitment to returning value to shareholders.
Negative Factors
Profitability Challenges
Negative profitability metrics indicate potential issues in cost management or pricing strategy, which could affect long-term financial stability.
Cash Position Decrease
The reduction in cash reserves may limit Dynavax's ability to invest in growth opportunities or weather financial downturns, impacting its strategic flexibility.
Seasonality Impact
Seasonal demand fluctuations can lead to revenue volatility, complicating financial planning and potentially affecting investor confidence.

Dynavax (DVAX) vs. SPDR S&P 500 ETF (SPY)

Dynavax Business Overview & Revenue Model

Company DescriptionDynavax Technologies Corporation, a biopharmaceutical company, focuses on developing and commercializing novel vaccines in the United States. The company markets HEPLISAV-B, a hepatitis B vaccine for prevention of infection caused by all known subtypes of hepatitis B virus in age 18 years and older in the United States and Europe. It also manufactures and sells CpG 1018, the adjuvant used in HEPLISAV-B. Dynavax Technologies Corporation has a collaboration agreement with Valneva Scotland Limited; agreement with Serum Institute of India Pvt. Ltd.; and sublicense agreement with Merck, Sharp & Dohme Corp. The company was formerly known as Double Helix Corporation and changed its name to Dynavax Technologies Corporation in September 1996. Dynavax Technologies Corporation was incorporated in 1996 and is headquartered in Emeryville, California.
How the Company Makes MoneyDynavax generates revenue primarily through the sale of its commercialized products, particularly HEPLISAV-B. The company benefits from a revenue model that includes direct sales to healthcare providers and partnerships with larger pharmaceutical companies for distribution and marketing. Additionally, Dynavax may receive milestone payments and royalties from collaborations and licensing agreements with other firms, which further contribute to its earnings. The company also focuses on expanding its product pipeline, which could lead to additional revenue streams in the future as new therapies and vaccines are developed and brought to market.

Dynavax Earnings Call Summary

Earnings Call Date:Oct 24, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Feb 19, 2026
Earnings Call Sentiment Positive
The earnings call highlighted strong revenue growth and strategic advancements in the company's pipeline and partnerships, notably with Vaxart. Despite a few concerns about potential seasonal impacts and a decrease in cash reserves, the company's overall financial health and strategic initiatives suggest a positive outlook.
Q3-2025 Updates
Positive Updates
HEPLISAV-B Revenue Growth
HEPLISAV-B generated approximately $90 million in net product revenue this quarter, representing a 13% increase year-over-year. The U.S. adult hepatitis B vaccine market share reached 46%, up from 44% in the prior year period.
Shingles Vaccine Program Progress
Progress was made in the shingles vaccine program with the initiation of Part 2 of the Phase I/II study in adults aged 70 years and older. Top line immunogenicity and safety results are expected in the second half of 2026.
Strategic Deal with Vaxart
Dynavax executed a strategic deal to access a Phase IIb COVID-19 oral vaccine candidate from Vaxart. The program has enrolled over 5,400 subjects in a Phase IIb safety and efficacy study.
Share Repurchase Program
Authorization of a new $100 million share repurchase plan, reflecting confidence in the company's long-term growth and commitment to enhancing shareholder value.
Financial Performance
GAAP net income of $27 million for the third quarter of 2025, compared to $18 million in the third quarter of 2024. Non-GAAP adjusted EBITDA improved to $36 million, up from $25 million last year.
Negative Updates
Seasonality Impact on HEPLISAV-B
Expectation of some seasonality impact in Q4 due to the holidays, which may slow down demand despite strong retail performance.
Cash Position Decrease
Cash and equivalents decreased to $648 million from $714 million at the end of 2024, primarily due to the $200 million share repurchase program.
Company Guidance
During the Dynavax Technologies Third Quarter 2025 Financial Results Conference Call, the company provided comprehensive guidance emphasizing their strategic growth initiatives and financial projections. Key metrics highlighted included a 13% year-over-year increase in HEPLISAV-B net product revenue, reaching $90 million, and an expansion in U.S. adult hepatitis B vaccine market share to 46%. The company reiterated its goal of achieving at least 60% market share by 2030. Dynavax also discussed the progress of their clinical pipeline, including the shingles vaccine program's advancement into Part 2 of the Phase I/II study and a strategic license agreement with Vaxart for an oral COVID-19 vaccine. Financially, they reported a GAAP net income of $27 million, up from $18 million in the same period last year, and adjusted EBITDA of $36 million. Additionally, Dynavax announced a new $100 million share repurchase program, following the completion of a $200 million program, underlining their commitment to enhancing shareholder value while maintaining robust financial health with $648 million in cash and equivalents.

Dynavax Financial Statement Overview

Summary
Dynavax shows positive revenue and cash flow growth, with a strong gross profit margin. However, profitability is a concern due to negative net income and EBIT margins. The balance sheet is stable with manageable leverage, but improvement in return on equity is needed.
Income Statement
65
Positive
Dynavax has shown a positive revenue growth rate of 4.5% in the TTM, indicating a recovery from previous declines. However, the company is currently experiencing negative net profit and EBIT margins, which highlight profitability challenges. The gross profit margin remains strong at over 82%, suggesting efficient cost management.
Balance Sheet
70
Positive
The debt-to-equity ratio has improved to 0.58 in the TTM, reflecting a manageable level of leverage. However, the return on equity is negative, indicating that the company is not generating sufficient returns on shareholders' equity. The equity ratio is stable, suggesting a solid capital structure.
Cash Flow
75
Positive
Dynavax's cash flow performance is strong, with a significant free cash flow growth rate of 21.9% in the TTM. The operating cash flow to net income ratio is healthy, indicating good cash generation relative to earnings. However, the free cash flow to net income ratio suggests that cash flow is not fully translating into net income.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue330.51M277.25M232.28M722.68M439.44M46.55M
Gross Profit274.90M227.80M182.12M460.53M265.87M32.64M
EBITDA-25.65M45.70M9.67M307.70M95.75M-46.84M
Net Income-43.40M27.31M-6.39M293.16M76.71M-75.24M
Balance Sheet
Total Assets946.51M986.26M997.10M985.85M1.04B353.27M
Cash, Cash Equivalents and Short-Term Investments647.82M713.83M742.30M624.39M545.95M165.04M
Total Debt285.02M254.42M256.91M258.01M257.38M217.85M
Total Liabilities412.37M389.46M375.02M404.84M816.87M294.58M
Stockholders Equity534.14M596.80M622.07M581.01M222.37M58.69M
Cash Flow
Free Cash Flow80.54M60.16M96.46M55.58M326.05M-103.32M
Operating Cash Flow90.63M66.51M100.56M62.72M335.53M-92.25M
Investing Cash Flow152.39M-18.04M-153.93M-316.00M14.22M-26.53M
Financing Cash Flow-202.74M-102.02M1.39M19.52M55.78M109.50M

Dynavax Technical Analysis

Technical Analysis Sentiment
Positive
Last Price11.43
Price Trends
50DMA
10.38
Positive
100DMA
10.46
Positive
200DMA
11.00
Positive
Market Momentum
MACD
0.29
Negative
RSI
64.02
Neutral
STOCH
87.86
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DVAX, the sentiment is Positive. The current price of 11.43 is above the 20-day moving average (MA) of 10.93, above the 50-day MA of 10.38, and above the 200-day MA of 11.00, indicating a bullish trend. The MACD of 0.29 indicates Negative momentum. The RSI at 64.02 is Neutral, neither overbought nor oversold. The STOCH value of 87.86 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for DVAX.

Dynavax Risk Analysis

Dynavax disclosed 40 risk factors in its most recent earnings report. Dynavax reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Dynavax Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
76
Outperform
$1.26B12.1314.84%-0.03%-27.66%
70
Outperform
$1.34B-7.14%26.73%-310.39%
70
Neutral
$1.46B28.7722.96%26.34%-32.79%
69
Neutral
$981.78M2.90%3.14%
64
Neutral
$1.90B51.747.83%48.87%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
44
Neutral
$1.20B-17.46%-1.19%5.06%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DVAX
Dynavax
11.43
-1.43
-11.12%
PCRX
Pacira Pharmaceuticals
23.81
6.90
40.80%
ANIP
ANI Pharmaceuticals
84.36
27.13
47.41%
AMPH
Amphastar Pharmaceuticals
27.36
-17.83
-39.46%
EVO
Evotec AG
3.26
-1.43
-30.49%
COLL
Collegium Pharmaceutical
46.23
15.73
51.57%

Dynavax Corporate Events

Dynavax Technologies Reports Strong Q3 Earnings and Strategic Growth
Nov 7, 2025

The recent earnings call from Dynavax Technologies conveyed a generally positive sentiment, underscored by robust revenue growth and strategic advancements in the company’s pipeline and partnerships, particularly with Vaxart. While there were some concerns regarding potential seasonal impacts and a decrease in cash reserves, the overall financial health and strategic initiatives of the company suggest a promising outlook.

Dynavax Technologies Advances in Pneumonic Plague Vaccine Study
Oct 27, 2025

Dynavax Technologies is conducting a Phase 2 study titled ‘Immunogenicity, Safety, and Tolerability of rF1V-1018 Vaccine in Adults 18 to 55 Years of Age.’ The study aims to evaluate the effectiveness, safety, and tolerability of the rF1V-1018 vaccine, which is significant for preventing pneumonic plague caused by aerosol exposure to Yersinia pestis.

Executive/Board Changes
Dynavax Announces Management Restructuring Changes
Neutral
Oct 16, 2025

On October 15, 2025, Dynavax Technologies Corporation’s Board of Directors approved changes in its management structure. David F. Novack will transition from his roles as President and Chief Operating Officer to Senior Vice President and Chief Operating Officer, effective January 1, 2026. Additionally, Robert Janssen, M.D. will be removed from his roles as Chief Medical Officer and Senior Vice President, Clinical Development, Medical and Regulatory Affairs, with his employment concluding by March 2, 2026, as the company searches for a successor.

The most recent analyst rating on (DVAX) stock is a Hold with a $10.00 price target. To see the full list of analyst forecasts on Dynavax stock, see the DVAX Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Dynavax Announces Positive Results for Shingles Vaccine
Positive
Aug 21, 2025

On August 21, 2025, Dynavax announced positive topline results from Part 1 of its Phase 1/2 clinical trial for Z-1018, a novel shingles vaccine candidate. The trial showed that Z-1018 has comparable immune responses to Shingrix, with a favorable tolerability profile, marking a significant step in Dynavax’s efforts to disrupt the shingles vaccine market. Plans are underway to advance Z-1018 into Part 2 of the trial for adults aged 70 and older, aiming to further de-risk the program before Phase 3 development.

The most recent analyst rating on (DVAX) stock is a Hold with a $11.00 price target. To see the full list of analyst forecasts on Dynavax stock, see the DVAX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 13, 2025