Financial StabilityDenali has cash of approximately $1.2 billion, which should take the company into 2028.
Regulatory ApprovalDenali announced it had initiated the BLA submission for accelerated approval of its lead asset tividenofusp alfa (tivi) in Hunter syndrome.
Therapeutic PotentialThere is significant potential for tivi to address both neurologic and systemic symptoms of Hunter syndrome, unlike the current standard-of-care option Elaprase, which does not cross the blood–brain barrier.