Censoring On Kaplan Meier CurvesThe level of censoring on the Kaplan Meier curves appears higher than expected, making it difficult to fully understand the extent of the censoring.
Control Arm PerformanceThe control arm of fulvestrant monotherapy may have underperformed, as the mPFS was expected to be around 3.5 months, but was only 2 months.
Treatment DiscontinuationsSafety data was sparse in the topline, but management indicated that the profile was better than that seen in the Ph1b, with lower discontinuation rates, hyperglycemia, and stomatitis.