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Ginkgo Bioworks Holdings, Inc. (DNA)
NYSE:DNA
US Market
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Ginkgo Bioworks Holdings (DNA) AI Stock Analysis

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DNA

Ginkgo Bioworks Holdings

(NYSE:DNA)

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Neutral 51 (OpenAI - 5.2)
Rating:51Neutral
Price Target:
$7.50
▼(-15.35% Downside)
Action:Reiterated
Date:05/09/26
The score is held down primarily by weak financial performance—sharp revenue declines, deep losses, and ongoing cash burn—despite strong gross margins. Offsetting factors include improved cost discipline and reaffirmed cash-burn guidance with substantial cash and no bank debt, plus moderately improving technical momentum; valuation remains constrained by negative earnings and no dividend yield data.
Positive Factors
Very high gross margins (~81%)
Sustained ~81% gross margins indicate strong unit economics and technical differentiation in cell engineering. High gross profit per dollar of revenue provides structural capacity to absorb R&D and scaling costs, enabling investment in platform and commercialization over the next several quarters.
Negative Factors
Sharp, multi-period revenue decline
Steep revenue contraction—both quarter and TTM—reflects weakened commercial traction and reduces leverage from high gross margins. Persistent top-line declines constrain reinvestment capacity and make achievement of scaled, recurring revenues from new channels materially less certain over the medium term.
Read all positive and negative factors
Positive Factors
Negative Factors
Very high gross margins (~81%)
Sustained ~81% gross margins indicate strong unit economics and technical differentiation in cell engineering. High gross profit per dollar of revenue provides structural capacity to absorb R&D and scaling costs, enabling investment in platform and commercialization over the next several quarters.
Read all positive factors

Ginkgo Bioworks Holdings Key Performance Indicators (KPIs)

Any
Any
Total Active Programs
Total Active Programs
Counts the number of ongoing projects or initiatives, indicating the company's innovation capacity and potential for future revenue streams.
Chart InsightsGinkgo Bioworks' active programs surged until late 2024, but a sharp decline followed, likely due to macroeconomic pressures and reduced demand for outsourcing R&D services. Despite this, the company is strategically expanding into new tools businesses and securing government contracts, which may offset some challenges. The earnings call highlighted significant cost reductions and improved profitability metrics, indicating a focus on financial resilience. However, ongoing net losses and a tough biotech capital market remain concerns, suggesting a cautious outlook for future program growth.
Data provided by:The Fly

Ginkgo Bioworks Holdings (DNA) vs. SPDR S&P 500 ETF (SPY)

Ginkgo Bioworks Holdings Business Overview & Revenue Model

Company Description
Ginkgo Bioworks Holdings, Inc., together with its subsidiaries, develops platform for cell programming. Its platform is used to program cells to enable biological production of products, such as novel therapeutics, food ingredients, and chemicals ...
How the Company Makes Money
Ginkgo primarily makes money through (1) platform services provided to partners and (2) downstream participation in the success of products that use Ginkgo-developed cell programs, supplemented by revenue from its biosecurity activities. 1) Platf...

Ginkgo Bioworks Holdings Earnings Call Summary

Earnings Call Date:May 07, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Aug 06, 2026
Earnings Call Sentiment Neutral
The call presents a balanced picture: meaningful operational and strategic progress in autonomous labs (Nebula), AI-driven experiments, partnerships and a strong cash position, alongside significant near-term financial challenges including a sharp revenue decline, ongoing losses, negative adjusted EBITDA and cash costs from excess leases and one-time payments. Execution and commercialization of Nebula, cloud lab and channel partnerships will determine whether the recent technical and commercial wins translate into durable revenue growth.
Positive Updates
Strong Cash Position and No Debt
Cash balance of $373 million with no bank debt as of Q1 2026, providing runway to invest in autonomous labs and related initiatives.
Negative Updates
Significant Revenue Decline
Revenue in Q1 2026 was $19M, down 49% year-over-year; excluding $7.5M of noncash revenue in Q1 2025 (BiomEdit termination), revenue declined 37% year-over-year.
Read all updates
Q1-2026 Updates
Negative
Strong Cash Position and No Debt
Cash balance of $373 million with no bank debt as of Q1 2026, providing runway to invest in autonomous labs and related initiatives.
Read all positive updates
Company Guidance
Ginkgo reaffirmed full‑year 2026 cash‑burn guidance of $125–$150 million and said cash burn best reflects continuing operations; the company entered Q1 with $373 million in cash and no bank debt. Q1 results (continuing ops) included revenue of $19 million (down 49% YoY, or down 37% ex‑$7.5M noncash BiomEdit revenue), R&D expense of $30 million (‑38% YoY from $49M), G&A of $13 million (‑35% YoY from $20M), net loss from continuing operations of $76 million (vs $83M), adjusted EBITDA of ‑$42 million (vs ‑$44M) which includes $16 million of excess‑lease carrying costs, and cash burn of $48 million (down 17% from $58M), a figure that included a $14 million Google Cloud payment tied to resetting a commitment that reduced future minimums by >$100 million and extended the term from 3 to 6 years; the biosecurity business closed as a divestiture on April 3 (reported as discontinued operations) and prior periods were recast with pro forma continuing‑operations info filed April 7.

Ginkgo Bioworks Holdings Financial Statement Overview

Summary
Financial statements show strong gross margins (~81%) but are outweighed by steep revenue contraction (TTM revenue -28.4%; Q1 revenue -49% YoY), very large losses (TTM net margin ~-250%), and continued cash burn (TTM FCF about -$183M). Balance sheet still has equity support, but leverage has risen (debt-to-equity ~0.93) and returns on equity are deeply negative.
Income Statement
24
Negative
Balance Sheet
46
Neutral
Cash Flow
28
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue141.31M170.16M227.04M251.46M477.71M313.84M
Gross Profit105.94M138.63M188.49M197.45M273.49M184.15M
EBITDA-206.10M-254.61M-484.39M-821.29M-2.06B-1.81B
Net Income-304.39M-312.76M-547.03M-892.87M-2.10B-1.83B
Balance Sheet
Total Assets1.03B1.12B1.38B1.67B2.54B2.07B
Cash, Cash Equivalents and Short-Term Investments373.46M422.62M561.57M944.07M1.32B1.55B
Total Debt410.70M417.08M467.73M239.31M442.59M23.03M
Total Liabilities589.92M611.11M661.39M568.19M803.04M503.61M
Stockholders Equity443.15M508.59M716.06M1.10B1.74B1.51B
Cash Flow
Free Cash Flow-183.27M-178.72M-382.13M-336.30M-304.47M-310.34M
Operating Cash Flow-165.97M-171.06M-319.58M-295.50M-252.20M-253.82M
Investing Cash Flow-18.47M-240.29M-62.24M-80.69M-67.39M-73.26M
Financing Cash Flow17.96M17.77M-1.74M-3.22M95.34M1.53B

Ginkgo Bioworks Holdings Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price8.86
Price Trends
50DMA
7.54
Positive
100DMA
8.30
Negative
200DMA
10.18
Negative
Market Momentum
MACD
0.11
Negative
RSI
60.82
Neutral
STOCH
86.63
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DNA, the sentiment is Neutral. The current price of 8.86 is above the 20-day moving average (MA) of 6.87, above the 50-day MA of 7.54, and below the 200-day MA of 10.18, indicating a neutral trend. The MACD of 0.11 indicates Negative momentum. The RSI at 60.82 is Neutral, neither overbought nor oversold. The STOCH value of 86.63 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for DNA.

Ginkgo Bioworks Holdings Risk Analysis

Ginkgo Bioworks Holdings disclosed 69 risk factors in its most recent earnings report. Ginkgo Bioworks Holdings reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Ginkgo Bioworks Holdings Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
66
Neutral
$290.70M13.9525.38%20.84%28.10%
56
Neutral
$799.79M-3.88-63.58%-61.87%10.39%
55
Neutral
$397.05M-0.03-5.71%40.38%
55
Neutral
$1.15B-5.03-51.34%14.68%94.97%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$473.00M-1.11-57.31%-40.48%39.96%
42
Neutral
$418.15M-4.54-85.71%-52.31%49.06%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DNA
Ginkgo Bioworks Holdings
7.71
-0.38
-4.70%
NAGE
Niagen Bioscience
3.65
-7.28
-66.61%
MNPR
Monopar Therapeutics Inc
59.27
22.37
60.62%
LYEL
Lyell Immunopharma
17.92
9.66
116.95%
JBIO
Jade Biosciences
23.36
15.94
214.76%
ABSI
AbSci
5.13
2.36
85.20%

Ginkgo Bioworks Holdings Corporate Events

Business Operations and StrategyFinancial DisclosuresM&A TransactionsRegulatory Filings and Compliance
Ginkgo Bioworks Divests Biosecurity Unit, Refocuses Core Operations
Neutral
Apr 7, 2026
On April 3, 2026, Ginkgo Bioworks, Inc., a subsidiary of Ginkgo Bioworks Holdings, completed the sale of all equity interests in Ginkgo Biosecurity, LLC to Tower Biosecurity, Inc., also known as Perimeter Systems, in exchange for a roughly 20% equ...
Business Operations and StrategyM&A Transactions
Ginkgo Bioworks Divests Biosecurity Unit, Retains Minority Stake
Neutral
Feb 27, 2026
On February 26, 2026, Ginkgo Bioworks, Inc., a wholly owned subsidiary of Ginkgo Bioworks Holdings, Inc., agreed to transfer all equity interests of Ginkgo Biosecurity, LLC to Tower Biosecurity, Inc., effectively divesting substantially all of the...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 09, 2026