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Rapport Therapeutics, Inc. (RAPP)
NASDAQ:RAPP
US Market

Rapport Therapeutics, Inc. (RAPP) AI Stock Analysis

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RAPP

Rapport Therapeutics, Inc.

(NASDAQ:RAPP)

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Neutral 55 (OpenAI - 5.2)
Rating:55Neutral
Price Target:
$31.00
▲(10.28% Upside)
The score is primarily held back by pre-revenue fundamentals with widening losses and increasing cash burn, despite a strong, low-debt balance sheet. Technicals are supportive (uptrend with positive momentum), but valuation is constrained by negative earnings and no dividend yield data.
Positive Factors
Clinical Trial Success
Successful Phase 2a trial results for RAP-219 in drug-resistant focal onset seizures highlight the potential for a new therapeutic option, strengthening Rapport's pipeline and supporting future revenue from successful commercialization.
Strong Balance Sheet
A strong balance sheet with low leverage provides financial stability and flexibility, enabling continued investment in R&D and supporting operations without immediate pressure to secure additional funding.
Pipeline Advancement
Advancing RAP-219 into Phase 3 trials indicates progress towards potential market approval, which could significantly enhance the company's market position and revenue prospects upon successful commercialization.
Negative Factors
Widening Losses
Widening losses reflect high operational costs without offsetting revenue, increasing reliance on external funding and raising the risk of financial strain if new capital is not secured.
Rising Cash Burn
Increasing cash burn rate can shorten the company's funding runway, necessitating frequent capital raises, which may dilute existing shareholders and impact long-term financial health.
Pre-Revenue Status
As a pre-revenue biotech, Rapport's financial sustainability heavily depends on securing external funding, which can be challenging and may affect the company's ability to sustain operations and advance its pipeline.

Rapport Therapeutics, Inc. (RAPP) vs. SPDR S&P 500 ETF (SPY)

Rapport Therapeutics, Inc. Business Overview & Revenue Model

Company DescriptionRapport Therapeutics, Inc., operates as a clinical-stage biopharmaceutical company that focuses on the discovery and development of transformational small molecule medicines for patients suffering from central nervous system (CNS) disorders. Its lead product candidate is receptor associated protein (RAP)-219, an investigational small molecule that is designed to inhibit TARPy8-containing AMPARs with picomolar affinity for the treatment of focal epilepsy and other CNS disorders, including peripheral neuropathic pain and bipolar disorder. The company also develops RAP-199, a TARPy8 targeted molecule with differentiated chemical and pharmacokinetic properties; and nicotinic acetylcholine receptor (nAChR) programs, such as a6 nAChR to treat chronic pain and a9a10 nAChR for the treatment of hearing disorders. The company was formerly known as Precision Neuroscience NewCo, Inc. and changed its name to Rapport Therapeutics, Inc. in October 2022. Rapport Therapeutics, Inc. was incorporated in 2022 and is based in Boston, Massachusetts.
How the Company Makes MoneyRapport Therapeutics, Inc. generates revenue primarily through the development and commercialization of its proprietary drug candidates. The company engages in partnerships and collaborations with other pharmaceutical firms to co-develop and license its therapies, which can provide milestone payments and royalties. Additionally, Rapport may secure funding through grants and research agreements to support its drug discovery and development efforts. The company's financial growth is supported by strategic alliances and the successful advancement of its drug pipeline through clinical trials.

Rapport Therapeutics, Inc. Financial Statement Overview

Summary
Rapport Therapeutics, Inc. shows strong equity financing and low leverage, which supports its financial stability despite the absence of revenue and increasing operational losses. The biotech sector's nature, with its reliance on external financing for research, poses risks if funding sources change. Continued focus on innovation and achieving revenue milestones is critical for future financial health.
Income Statement
Rapport Therapeutics, Inc. has reported no revenue for the past three years, with increasing losses, as evidenced by the rising net loss from $10.65 million in 2022 to $78.31 million in 2024. This indicates a challenging revenue generation environment, common in early-stage biotech companies focused on research and development without commercial products.
Balance Sheet
The company maintains a strong equity position with stockholders' equity increasing from $19.51 million in 2022 to $305.43 million in 2024. The low debt levels, with a debt-to-equity ratio of approximately 0.005, suggest financial stability. However, the lack of revenue generation poses a risk to long-term sustainability if financing sources diminish.
Cash Flow
Operating cash flow has significantly deteriorated, with free cash flow going from -$3.53 million in 2022 to -$67.23 million in 2024. The heavy reliance on financing cash flows, notably a $221.63 million inflow in 2024, supports operations but highlights the potential cash flow challenges if external funding becomes scarce.
BreakdownTTMDec 2024Dec 2023Dec 2022
Income Statement
Total Revenue0.000.000.000.00
Gross Profit0.00-839.00K-112.00K-15.00K
EBITDA-106.04M-77.47M-34.66M-10.35M
Net Income-97.70M-78.31M-34.79M-10.65M
Balance Sheet
Total Assets535.32M314.93M155.42M31.60M
Cash, Cash Equivalents and Short-Term Investments513.03M305.28M147.56M31.16M
Total Debt11.87M1.48M2.15M10.44M
Total Liabilities23.71M9.51M14.48M12.10M
Stockholders Equity511.62M305.43M140.94M19.50M
Cash Flow
Free Cash Flow-77.89M-67.23M-28.82M-3.53M
Operating Cash Flow-77.22M-64.83M-27.18M-3.24M
Investing Cash Flow18.78M-170.14M-78.86M-5.28M
Financing Cash Flow270.48M221.63M145.14M39.69M

Rapport Therapeutics, Inc. Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price28.11
Price Trends
50DMA
27.98
Positive
100DMA
25.23
Positive
200DMA
18.44
Positive
Market Momentum
MACD
0.57
Positive
RSI
44.81
Neutral
STOCH
36.64
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RAPP, the sentiment is Neutral. The current price of 28.11 is below the 20-day moving average (MA) of 29.86, above the 50-day MA of 27.98, and above the 200-day MA of 18.44, indicating a neutral trend. The MACD of 0.57 indicates Positive momentum. The RSI at 44.81 is Neutral, neither overbought nor oversold. The STOCH value of 36.64 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for RAPP.

Rapport Therapeutics, Inc. Risk Analysis

Rapport Therapeutics, Inc. disclosed 86 risk factors in its most recent earnings report. Rapport Therapeutics, Inc. reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Rapport Therapeutics, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (55)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
70
Outperform
$1.05B6.5017.68%-86.40%30.72%
61
Neutral
$1.49B14.2515.17%9.76%88.06%
55
Neutral
$1.34B-10.44-23.41%-37.07%
55
Neutral
$6.65B3.83-15.92%6.20%10.91%7.18%
51
Neutral
$500.64M-7.59-28.78%70.19%
45
Neutral
$922.26M-8.42-25.43%3.18%
* General Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RAPP
Rapport Therapeutics, Inc.
28.11
10.12
56.25%
INVA
Innoviva
19.87
2.49
14.33%
ELVN
Enliven Therapeutics
15.54
-8.53
-35.44%
CVAC
CureVac
4.67
0.23
5.18%
LENZ
LENZ Therapeutics
16.00
-11.26
-41.31%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 30, 2025