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CryoPort Inc (CYRX)
NASDAQ:CYRX
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CryoPort (CYRX) AI Stock Analysis

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CYRX

CryoPort

(NASDAQ:CYRX)

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Neutral 54 (OpenAI - 4o)
Rating:54Neutral
Price Target:
$9.50
▼(-1.25% Downside)
CryoPort's overall stock score reflects significant financial challenges, particularly in cash flow generation and profitability. While the earnings call provided a positive outlook with growth in key segments, the technical analysis presents mixed signals, and the valuation metrics suggest potential overvaluation. The company's ability to improve financial performance and manage external risks will be crucial for future stock performance.
Positive Factors
Revenue Growth in Key Segments
Strong growth in critical segments like Life Sciences Services and Products indicates robust demand and market expansion, supporting long-term revenue stability.
Strategic Partnerships
The partnership with DHL enhances CryoPort's logistics capabilities and market reach in APAC and EMEA, strengthening its competitive position.
New Product Launches
Introducing advanced cryogenic systems supports product diversification and technological leadership, driving future growth and market differentiation.
Negative Factors
Declining Revenue Growth
A negative revenue growth trend poses a risk to long-term financial health, indicating challenges in maintaining market share and operational efficiency.
Cash Flow Challenges
Negative cash flow highlights inefficiencies in operations and limits the company's ability to invest in growth opportunities, impacting financial stability.
High Operating Expenses
Elevated operating expenses reduce profitability, challenging the company's ability to improve margins and sustain long-term financial performance.

CryoPort (CYRX) vs. SPDR S&P 500 ETF (SPY)

CryoPort Business Overview & Revenue Model

Company DescriptionCryoport, Inc., a life sciences services company, provides temperature-controlled logistics solutions in the Americas, Europe, the Middle East, Africa, and the Asia Pacific. The company offers Cryoportal, a cloud-based logistics management platform that supports the management of shipments, which includes order entry, document preparation, customs documentation, courier management, real-time shipment tracking and monitoring, issue resolution, and regulatory compliance requirements; and CryoPort Express Shippers, which is used to ensure that the stability of shipped biologic commodities is maintained throughout the shipping cycle. It also provides information dashboards and validation documentation for shipments through data collected by the SmartPak Condition Monitoring System; and vacuum insulated aluminum dewars and cryogenic freezers systems. In addition, the company offers biological specimen cryopreservation storage and maintenance; archiving, monitoring, tracking, receipt, and delivery of samples; transportation of frozen biological specimens to and from customer locations; and management of incoming and outgoing biological specimens, as well as provides logistics support and management; and short-term logistics and engineering consulting services. It serves biopharma/pharma, animal health, and human reproductive medicine markets. The company was founded in 1999 and is headquartered in Brentwood, Tennessee.
How the Company Makes MoneyCryoPort generates revenue primarily through its logistics services, particularly the shipping and storage of temperature-sensitive biological materials. Key revenue streams include fees for CryoPort Express® shipping services, which are charged based on the volume and distance of shipments. Additionally, the company earns income from long-term contracts with pharmaceutical and biotechnology companies, which require ongoing logistics support for clinical trials and commercial product distribution. Significant partnerships with leading biopharmaceutical firms enhance its market position and contribute to consistent revenue growth. The company also benefits from increasing demand for advanced therapies, including cell and gene therapies, which require specialized logistics solutions.

CryoPort Earnings Call Summary

Earnings Call Date:Nov 04, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 11, 2026
Earnings Call Sentiment Positive
The earnings call presented a mostly positive outlook with strong growth in key segments, strategic expansions, and increased clinical trial support. However, there are some concerns about sequential revenue guidance and external factors like the government shutdown impacting operations.
Q3-2025 Updates
Positive Updates
Growth in Life Sciences Services and Products
Double-digit growth in both Life Sciences Services and Life Sciences Product segments. Revenue from commercial cell and gene therapy grew 36% year-over-year to $8.3 million.
Expansion and New Product Launches
Launch of MVE Biological Solutions next-generation SC4/2V and SC4/3V vapor shippers. Opening of logistics portion of Cryoport Systems' new global supply chain center at Charles de Gaulle Airport in Paris.
Strategic Partnership with DHL
Progress in implementing the strategic partnership with DHL Group, enhancing positioning in APAC and EMEA regions.
Increased Clinical Trial Support
Supporting a record total of 745 global clinical trials, with 83 in Phase III, representing 70% of cell and gene therapy clinical trials.
Revenue Guidance Update
Full-year 2025 outlook updated to a range of $170 million to $174 million, reflecting 8% to 11% revenue growth over the prior year.
Negative Updates
Sequential Revenue Guidance Decline
The high end of the guidance implies a sequential decline in revenues despite positive momentum across the business.
Impact of Government Shutdown
Potential delays in filing activities due to the government shutdown, affecting the timing of some revenues.
Challenges in China Market
No expected growth in the China market for 2026, with strategies still being implemented.
Company Guidance
During Cryoport's third-quarter 2025 earnings call, the company reported double-digit revenue growth in its Life Sciences Services and Life Sciences Product segments. Revenue from commercial cell and gene therapy support increased by 36% year-over-year to $8.3 million, while overall Life Sciences revenue grew 16% year-over-year, comprising 55% of total revenue from continuing operations. The Bioservices revenue within Life Sciences increased by 21%. The company also launched new cryogenic systems, contributing to a 15% year-over-year growth in the life sciences product market. Cryoport revised its full-year 2025 revenue guidance to $170 million to $174 million, despite potential impacts from the current U.S. government shutdown. The company continues to support a large portfolio of clinical and commercial gene therapies, with 745 global clinical trials, including 83 in Phase III.

CryoPort Financial Statement Overview

Summary
CryoPort faces significant financial challenges, with declining revenues and profitability pressures. While the balance sheet shows some improvement in leverage and return on equity, cash flow generation remains a critical issue. The company needs to focus on improving operational efficiency and cash flow management to enhance its financial health and stability.
Income Statement
45
Neutral
CryoPort's income statement reveals a challenging financial landscape. The company has experienced a decline in revenue growth, with a negative growth rate of -6.13% in the TTM period. Despite a relatively healthy gross profit margin of 46.58%, the net profit margin is significantly impacted by high operating expenses, resulting in a negative EBIT margin of -22.88%. The company has managed to achieve a positive net income in the TTM period, but the overall profitability remains weak due to historical losses.
Balance Sheet
55
Neutral
The balance sheet shows a moderate financial position with a debt-to-equity ratio of 0.45, indicating manageable leverage. The return on equity has improved to 14.78% in the TTM period, reflecting better utilization of equity. However, the equity ratio stands at 66.28%, suggesting a reliance on equity financing. The company has shown some improvement in its financial stability, but the high level of debt in previous years remains a concern.
Cash Flow
40
Negative
CryoPort's cash flow statement indicates ongoing challenges in cash generation. The operating cash flow is negative, and the free cash flow has declined by -7.46% in the TTM period. The operating cash flow to net income ratio is negative, highlighting inefficiencies in converting income into cash. Although the free cash flow to net income ratio is positive, it is primarily due to the positive net income rather than strong cash flow generation.
BreakdownTTMDec 2023Dec 2022Dec 2021Dec 2020Dec 2019
Income Statement
Total Revenue190.26M233.25M237.28M222.61M222.61M78.70M
Gross Profit88.62M99.33M103.87M96.58M96.58M36.33M
EBITDA-14.10M-66.36M-6.19M-248.91M-248.91M-20.31M
Net Income67.58M-99.59M-37.33M-275.53M-275.53M-32.69M
Balance Sheet
Total Assets773.93M703.49M957.74M1.04B1.11B552.40M
Cash, Cash Equivalents and Short-Term Investments425.98M261.75M456.75M523.32M628.80M93.32M
Total Debt228.52M250.70M416.00M435.91M427.06M130.92M
Total Liabilities258.54M301.59M468.72M482.91M471.14M169.71M
Stockholders Equity515.39M401.90M489.02M555.84M641.83M382.70M
Cash Flow
Free Cash Flow-32.50M-33.58M-45.66M-26.05M-16.88M-24.54M
Operating Cash Flow-14.98M-16.32M-757.00K-1.85M8.13M-14.87M
Investing Cash Flow253.75M176.81M36.05M-59.68M-469.25M-382.31M
Financing Cash Flow-16.91M-161.53M-23.80M-39.17M564.34M385.58M

CryoPort Technical Analysis

Technical Analysis Sentiment
Positive
Last Price9.62
Price Trends
50DMA
9.43
Positive
100DMA
8.88
Positive
200DMA
7.58
Positive
Market Momentum
MACD
<0.01
Negative
RSI
57.82
Neutral
STOCH
95.51
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CYRX, the sentiment is Positive. The current price of 9.62 is above the 20-day moving average (MA) of 8.87, above the 50-day MA of 9.43, and above the 200-day MA of 7.58, indicating a bullish trend. The MACD of <0.01 indicates Negative momentum. The RSI at 57.82 is Neutral, neither overbought nor oversold. The STOCH value of 95.51 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CYRX.

CryoPort Risk Analysis

CryoPort disclosed 33 risk factors in its most recent earnings report. CryoPort reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

CryoPort Peers Comparison

Overall Rating
UnderperformOutperform
Sector (63)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
75
Outperform
$65.05B16.1114.98%2.10%1.14%4.99%
73
Outperform
$16.64B50.9419.26%-0.30%-11.02%
73
Outperform
$16.13B13.8413.83%3.10%12.89%3.12%
65
Neutral
$16.51B30.0115.13%1.01%-1.60%4.87%
63
Neutral
$10.79B15.437.44%2.01%2.89%-14.66%
63
Neutral
$5.81B66.422.94%16.94%-14.01%
54
Neutral
$461.62M-9.32-9.96%-15.86%66.42%
* Industrials Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CYRX
CryoPort
9.62
1.84
23.65%
XPO
XPO
142.06
-12.47
-8.07%
FDX
FedEx
275.68
-14.20
-4.90%
JBHT
JB Hunt
173.96
-13.10
-7.00%
ZTO
ZTO Express
20.65
2.31
12.60%
GXO
GXO Logistics
50.74
-9.66
-15.99%

CryoPort Corporate Events

CryoPort Inc’s Earnings Call: Growth and Challenges
Nov 6, 2025

CryoPort Inc’s Recent Earnings Call: A Positive Outlook Amid Challenges

Cryoport Reports Strong Q3 2025 Revenue Growth
Nov 5, 2025

Cryoport, Inc. is a global leader in temperature-controlled supply chain solutions for the life sciences sector, focusing on regenerative medicine and providing comprehensive services to biopharmaceutical companies and research organizations.

CryoPort Delays 10-Q Filing Due to Compilation Challenges
Aug 12, 2025

CryoPort, Inc. has announced a delay in filing its Form 10-Q (Quarter Report) for the financial period ending June 30, 2025. The company cites the inability to compile the report without unreasonable effort or expense as the primary reason for the delay. CryoPort expects to file the report within the additional time allowed, specifically within five calendar days following the prescribed due date. The company has indicated that there will be significant changes in the results of operations compared to the same period last year. These changes were highlighted in a press release issued on August 5, 2025. CryoPort is committed to maintaining compliance and the notification was signed by CEO Robert S Stefanovich.

The most recent analyst rating on (CYRX) stock is a Buy with a $15.00 price target. To see the full list of analyst forecasts on CryoPort stock, see the CYRX Stock Forecast page.

Cryoport Inc’s Earnings Call Highlights Growth and Optimism
Aug 7, 2025

Cryoport Inc’s recent earnings call painted a picture of optimism, underscored by robust revenue growth and strategic partnerships. The company showcased its resilience and strategic foresight, despite facing some regulatory and market challenges. The overall sentiment was positive, driven by the company’s expanding service offerings and market positioning.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 25, 2025