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CryoPort Inc (CYRX)
NASDAQ:CYRX
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CryoPort (CYRX) AI Stock Analysis

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CYRX

CryoPort

(NASDAQ:CYRX)

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Neutral 63 (OpenAI - 5.2)
Rating:63Neutral
Price Target:
$16.50
▲(79.15% Upside)
Action:Reiterated
Date:06/10/26
Overall score reflects weak underlying cash generation and still-negative operating profitability as the main constraint, partially offset by strong technical uptrend and a constructive earnings update (raised revenue guidance and improving adjusted EBITDA trajectory). Valuation is supportive (P/E ~10) but is tempered by the cash-flow and profitability profile.
Positive Factors
Market position in cell & gene therapy
A deep and growing clinical pipeline (766 trials, 91 Phase III, 21 commercial therapies) creates durable, multi-year demand and a high-probability conversion funnel from clinical support to recurring commercial logistics, underpinning steady revenue and long-term customer relationships.
Negative Factors
Weak cash generation
Material negative free cash flow and continued negative operating cash flow mean the business is not yet self-funding. Persistent cash burn constrains reinvestment capacity and increases reliance on external financing, which can limit strategic optionality during stress.
Read all positive and negative factors
Positive Factors
Negative Factors
Market position in cell & gene therapy
A deep and growing clinical pipeline (766 trials, 91 Phase III, 21 commercial therapies) creates durable, multi-year demand and a high-probability conversion funnel from clinical support to recurring commercial logistics, underpinning steady revenue and long-term customer relationships.
Read all positive factors

CryoPort Key Performance Indicators (KPIs)

Any
Any
Revenue by Geography
Revenue by Geography
Chart Insights
Data provided by:The Fly

CryoPort (CYRX) vs. SPDR S&P 500 ETF (SPY)

CryoPort Business Overview & Revenue Model

Company Description
Cryoport, Inc. operates as a specialized service provider within the life sciences sector, delivering global temperature-controlled supply chain solutions across the Americas, Europe, the Middle East, Africa, and the Asia Pacific region. Central t...
How the Company Makes Money
CryoPort primarily makes money by providing end-to-end, temperature-controlled logistics services for biopharmaceutical customers, with revenue largely generated on a per-shipment and/or contracted-services basis. Key revenue streams include: (1) ...

CryoPort Earnings Call Summary

Earnings Call Date:May 04, 2026
(Q1-2026)
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% Change Since: |
Next Earnings Date:Aug 11, 2026
Earnings Call Sentiment Positive
The call presented a predominantly positive operational and financial picture: strong 16% revenue growth, double-digit expansion across services and products, record clinical trial support, product innovation (Fusion 800), and a $2.2M improvement in adjusted EBITDA. Management raised full-year revenue guidance and expects positive adjusted EBITDA in H2 2026. Key near-term cautions include a conservative guide raise despite a beat, the company not yet at positive adjusted EBITDA, product-margin mix variability, and multi-quarter ramps for IntegraCell and new facilities that limit 2026 contribution. Overall the positives (top-line growth, pipeline depth, milestones, margin improvement initiatives, and operational expansions) materially outweigh the identified lowlights.
Positive Updates
Top-Line Growth
Revenue of $47.8 million in Q1 2026, up 16% year over year, representing a strong start to the year and prompting an upward revision to full-year revenue guidance of $192 million to $196 million.
Negative Updates
Cautious Guiding Despite Beat
Although Q1 beat consensus by $3 million, management raised full-year guidance only modestly ($1 million), citing macroeconomic uncertainty and taking a conservative stance early in the year.
Read all updates
Q1-2026 Updates
Negative
Top-Line Growth
Revenue of $47.8 million in Q1 2026, up 16% year over year, representing a strong start to the year and prompting an upward revision to full-year revenue guidance of $192 million to $196 million.
Read all positive updates
Company Guidance
Management raised full‑year 2026 revenue guidance to $192–$196 million (continuing operations) after a strong Q1 start with revenue of $47.8 million, up 16% year‑over‑year; Q1 commercial cell & gene therapy revenue was $9.1M (up 26% YoY), clinical trial revenue was $12.9M (up 18% YoY), Life Sciences Services revenue rose 18% with biostorage/bioservices up 21%, and Life Sciences Products grew 15%; the company now supports 766 global clinical trials (net +55 YoY) including 91 Phase III programs, supports 21 commercial therapies with up to eight potential new approvals this year (five with PDUFA dates), and reported a $2.2M year‑over‑year improvement in adjusted EBITDA from continuing operations (Q1 adjusted EBITDA ~‑$0.6M), reiterating an expectation to reach positive adjusted EBITDA in the second half of 2026 and noting they will reassess guidance quarterly.

CryoPort Financial Statement Overview

Summary
Revenue growth is modest (TTM ~+3.8%) with a healthy gross margin (~47%) and manageable leverage (debt-to-equity ~0.46). However, operating profitability remains negative and cash flow quality is weak (negative operating cash flow and materially negative free cash flow), creating a gap between positive net income and underlying cash generation.
Income Statement
56
Neutral
Balance Sheet
68
Positive
Cash Flow
28
Negative
BreakdownTTMDec 2025Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue182.94M176.18M233.25M237.28M222.61M222.61M
Gross Profit86.33M83.05M99.33M103.87M96.58M96.58M
EBITDA-6.31M-2.10M-66.36M-6.19M-248.91M-248.91M
Net Income77.16M78.30M-99.59M-37.33M-275.53M-275.53M
Balance Sheet
Total Assets763.61M764.99M703.49M957.74M1.04B1.11B
Cash, Cash Equivalents and Short-Term Investments403.63M411.21M261.75M456.75M523.32M628.80M
Total Debt230.49M230.72M250.70M416.00M435.91M427.06M
Total Liabilities268.62M262.35M301.59M468.72M482.91M471.14M
Stockholders Equity494.99M502.64M401.90M489.02M555.84M641.83M
Cash Flow
Free Cash Flow-24.06M-28.09M-33.58M-45.66M-26.05M-16.88M
Operating Cash Flow-503.00K-8.58M-16.32M-757.00K-1.85M8.13M
Investing Cash Flow263.12M250.32M176.81M36.05M-59.68M-469.25M
Financing Cash Flow-20.80M-21.07M-161.53M-23.80M-39.17M564.34M

CryoPort Technical Analysis

Technical Analysis Sentiment
Positive
Last Price9.21
Price Trends
50DMA
12.38
Positive
100DMA
10.52
Positive
200DMA
10.04
Positive
Market Momentum
MACD
0.77
Positive
RSI
55.30
Neutral
STOCH
8.38
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CYRX, the sentiment is Positive. The current price of 9.21 is below the 20-day moving average (MA) of 14.76, below the 50-day MA of 12.38, and below the 200-day MA of 10.04, indicating a neutral trend. The MACD of 0.77 indicates Positive momentum. The RSI at 55.30 is Neutral, neither overbought nor oversold. The STOCH value of 8.38 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CYRX.

CryoPort Risk Analysis

CryoPort disclosed 33 risk factors in its most recent earnings report. CryoPort reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

CryoPort Peers Comparison

Overall Rating
UnderperformOutperform
Sector (63)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
78
Outperform
$16.84B13.1214.20%2.98%15.87%1.18%
73
Outperform
$80.65B18.3315.76%1.94%4.69%17.55%
73
Outperform
$27.27B44.2817.30%0.89%0.58%17.20%
64
Neutral
$26.73B76.7719.04%3.63%-11.81%
63
Neutral
$10.79B15.437.44%2.01%2.89%-14.66%
63
Neutral
$724.79M9.4516.16%-14.85%62.35%
56
Neutral
$5.73B43.194.46%10.38%84.52%
* Industrials Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CYRX
CryoPort
14.62
7.69
110.97%
XPO
XPO
228.33
105.77
86.30%
FDX
FedEx
338.31
159.67
89.38%
JBHT
JB Hunt
289.36
148.23
105.04%
ZTO
ZTO Express
22.83
5.66
32.96%
GXO
GXO Logistics
49.70
6.44
14.89%

CryoPort Corporate Events

Business Operations and StrategyExecutive/Board ChangesShareholder Meetings
Cryoport Shareholders Back Board, Auditor and Equity Plan
Positive
Jun 9, 2026
At its annual meeting on June 5, 2026, Cryoport, Inc. shareholders elected six directors, including Linda Baddour and CEO Jerrell W. Shelton, to serve until the 2027 meeting, reaffirming the company’s current board leadership. Investors also...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 10, 2026