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CryoPort Inc (CYRX)
NASDAQ:CYRX
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CryoPort (CYRX) AI Stock Analysis

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CYRX

CryoPort

(NASDAQ:CYRX)

Rating:68Neutral
Price Target:
$9.50
▲(25.66% Upside)
CryoPort's overall stock score reflects a mix of significant financial challenges and promising strategic initiatives. The company's financial performance is a major concern due to persistent losses and negative cash flows. However, strong technical indicators, attractive valuation, and positive earnings call sentiment provide a counterbalance. The strategic partnership with DHL further enhances the company's growth prospects, contributing to a moderately positive outlook.
Positive Factors
Financial Performance
Strong broad-based beat in the quarter highlights improvement, with revenue ahead of expectations.
Market Position
CYRX holds a dominant market-leading position with 70% market share in the Cell & Gene Therapy services sector.
Negative Factors
Policy Changes
The full impact of policy changes, including broad-based tariffs and new FDA leadership, is not yet reflected in the current results.
Tariffs
Steel and aluminum tariffs of 25% went into effect, but the full impact is not yet reflected in the results.

CryoPort (CYRX) vs. SPDR S&P 500 ETF (SPY)

CryoPort Business Overview & Revenue Model

Company DescriptionCryoport, Inc., a life sciences services company, provides temperature-controlled logistics solutions in the Americas, Europe, the Middle East, Africa, and the Asia Pacific. The company offers Cryoportal, a cloud-based logistics management platform that supports the management of shipments, which includes order entry, document preparation, customs documentation, courier management, real-time shipment tracking and monitoring, issue resolution, and regulatory compliance requirements; and CryoPort Express Shippers, which is used to ensure that the stability of shipped biologic commodities is maintained throughout the shipping cycle. It also provides information dashboards and validation documentation for shipments through data collected by the SmartPak Condition Monitoring System; and vacuum insulated aluminum dewars and cryogenic freezers systems. In addition, the company offers biological specimen cryopreservation storage and maintenance; archiving, monitoring, tracking, receipt, and delivery of samples; transportation of frozen biological specimens to and from customer locations; and management of incoming and outgoing biological specimens, as well as provides logistics support and management; and short-term logistics and engineering consulting services. It serves biopharma/pharma, animal health, and human reproductive medicine markets. The company was founded in 1999 and is headquartered in Brentwood, Tennessee.
How the Company Makes MoneyCryoPort makes money primarily through its temperature-controlled logistics solutions, which include transportation and storage services for the life sciences sector. The company generates revenue by providing these specialized logistics services to pharmaceutical and biotechnology companies, research institutions, and healthcare providers. Key revenue streams include fees charged for logistics and shipping services, as well as storage and handling of biological materials. CryoPort also benefits from long-term contracts and partnerships with major companies in the life sciences industry, which provide a steady stream of income. Additionally, the company's consulting services contribute to its revenue by offering expertise in supply chain management and regulatory compliance for temperature-sensitive products.

CryoPort Earnings Call Summary

Earnings Call Date:Aug 05, 2025
(Q2-2025)
|
% Change Since: 12.17%|
Next Earnings Date:Nov 06, 2025
Earnings Call Sentiment Positive
Cryoport's earnings call highlighted strong revenue growth, strategic partnerships, and expanding service offerings, suggesting a positive trajectory. However, challenges such as a temporary client distribution pause, regulatory setbacks, and stagnant growth in China present notable obstacles. Despite these challenges, the overall sentiment remains optimistic due to the company's strategic initiatives and market positioning.
Q2-2025 Updates
Positive Updates
Strong Double-Digit Revenue Growth
Cryoport reported a 14% overall increase in total revenue from operations, with service revenue growing by 21% year-over-year, accounting for 54% of total revenue from continuing operations.
Commercial Cell and Gene Therapies Revenue Surge
Revenue from commercial cell and gene therapies increased by 33%, highlighting the rising demand for Cryoport's integrated temperature control supply chain platform.
BioStorage/BioServices Growth
BioStorage/BioServices revenue grew by 28%, indicating strong demand for Cryoport's storage and service offerings.
Successful Strategic Partnership with DHL
A strategic partnership with DHL Group was launched, resulting in approximately $200 million in cash payments to Cryoport, enhancing global biologics capabilities and positioning Cryoport for expansion in Asia Pac and EMEA.
Continued Clinical Trial Support
Cryoport supported a record 728 clinical trials, approximately 70% of industry cell and gene therapy trials, with expectations for additional application filings and therapy approvals.
MVE Product Line Expansion
An 8% year-over-year revenue growth was reported in Life Sciences products, driven by demand from animal health customers and the launch of new vapor shippers and cryogenic storage systems.
Negative Updates
Impact from Client Distribution Pause
One gene therapy client temporarily paused distribution of their commercial therapy, leading to an estimated $2 million revenue impact for the remainder of the year.
FDA and MAA Negative Opinions
Five clients received negative opinions from the FDA or MAA, impacting the expected approvals for their therapies, though meetings with regulators are ongoing to find a path forward.
Flat Market in China
No expected market expansion or recovery in China for 2025, with guidance reflecting this stagnation.
Company Guidance
In the second quarter of 2025, Cryoport reported significant financial growth across its Life Sciences Services, with service revenue increasing by 21% year-over-year and accounting for 54% of total revenue from continuing operations. This was driven by a 33% increase in revenue from commercial cell and gene therapies and a 28% growth in BioStorage/BioServices. Additionally, Life Sciences products saw an 8% year-over-year revenue growth. The company achieved a 14% overall increase in total revenue from operations and improved gross margins, alongside a meaningful rise in adjusted EBITDA. Cryoport reaffirmed its full-year 2025 revenue guidance, bolstered by the completion of a strategic partnership with DHL Group, which included a $200 million cash infusion from the sale of CRYOPDP. This partnership is expected to enhance their global biologics capabilities, particularly in the Asia Pacific (APAC) and Europe, Middle East, and Africa (EMEA) regions.

CryoPort Financial Statement Overview

Summary
CryoPort faces significant financial challenges, with declining revenues, negative net income margins, and negative cash flows. Despite a solid gross profit margin and improved leverage metrics, the company struggles with profitability and cash management.
Income Statement
35
Negative
CryoPort's income statement reflects significant challenges. The company has experienced declining revenues from $237.3 million in 2022 to $214.8 million in the TTM period ending March 2025. Despite a healthy gross profit margin of approximately 42.9% in TTM, the company struggles with negative EBIT and net income margins, indicating consistent operating and net losses. The TTM net profit margin is -50.2%, a deterioration from -15.7% in 2022, highlighting worsening profitability.
Balance Sheet
55
Neutral
CryoPort's balance sheet shows mixed signals. The debt-to-equity ratio has improved slightly to 0.61 in TTM from 0.78 in 2022, indicating a reduction in leverage, but the company's equity ratio has decreased to 57.0%, reflecting reduced equity relative to assets. The return on equity remains negative due to ongoing losses, with a TTM ROE of approximately -27.0%. The balance sheet displays adequate liquidity with $244 million in cash and short-term investments, though overall financial stability is challenged by recurring losses.
Cash Flow
40
Negative
CryoPort's cash flow statement is concerning, with negative operating and free cash flows. The TTM operating cash flow is -$17.4 million, further stressing financial operations. Free cash flow is also negative at -$34.4 million, indicating insufficient cash generation to cover capital expenditures. The free cash flow to net income ratio remains below 1, demonstrating cash flow struggles in tandem with net losses.
BreakdownTTMDec 2023Dec 2022Dec 2021Dec 2020Dec 2019
Income Statement
Total Revenue214.83M228.38M233.25M237.28M222.61M78.70M
Gross Profit92.20M99.63M99.33M103.87M96.58M36.33M
EBITDA-69.31M-78.61M-66.36M-6.19M-248.91M-20.31M
Net Income-107.84M-114.76M-99.59M-37.33M-275.53M-32.69M
Balance Sheet
Total Assets699.84M703.49M957.74M1.04B1.11B552.40M
Cash, Cash Equivalents and Short-Term Investments244.03M261.75M456.75M523.32M628.80M93.32M
Total Debt242.67M250.70M416.00M435.91M427.06M130.92M
Total Liabilities301.03M301.59M468.72M482.91M471.14M169.71M
Stockholders Equity398.81M401.90M489.02M555.84M641.83M382.70M
Cash Flow
Free Cash Flow-34.39M-33.58M-45.66M-26.05M-16.88M-24.54M
Operating Cash Flow-17.40M-16.32M-757.00K-1.85M8.13M-14.87M
Investing Cash Flow176.29M176.81M36.05M-59.68M-469.25M-382.31M
Financing Cash Flow-162.23M-161.53M-23.80M-39.17M564.34M385.58M

CryoPort Technical Analysis

Technical Analysis Sentiment
Positive
Last Price7.56
Price Trends
50DMA
7.15
Positive
100DMA
6.56
Positive
200DMA
6.92
Positive
Market Momentum
MACD
0.16
Negative
RSI
51.03
Neutral
STOCH
54.25
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CYRX, the sentiment is Positive. The current price of 7.56 is above the 20-day moving average (MA) of 7.52, above the 50-day MA of 7.15, and above the 200-day MA of 6.92, indicating a bullish trend. The MACD of 0.16 indicates Negative momentum. The RSI at 51.03 is Neutral, neither overbought nor oversold. The STOCH value of 54.25 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CYRX.

CryoPort Risk Analysis

CryoPort disclosed 33 risk factors in its most recent earnings report. CryoPort reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

CryoPort Peers Comparison

Overall Rating
UnderperformOutperform
Sector (71)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
71
Outperform
¥260.63B14.788.48%2.81%6.37%12.90%
68
Neutral
$379.04M5.67-8.54%-10.16%
64
Neutral
$279.09M16.818.09%7.18%186.98%
59
Neutral
$56.94M-790.22%1.75%5.85%
54
Neutral
$920.30M-147.96%0.86%50.11%-682.50%
54
Neutral
$155.13M-23.18%49.48%80.17%
47
Neutral
$212.94M124.65-53.71%-7.95%-83128.57%
* Industrials Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CYRX
CryoPort
7.56
-0.27
-3.45%
AIRT
Air T
21.07
-1.51
-6.69%
FWRD
Forward Air
30.25
5.49
22.17%
RLGT
Radiant Logistics
5.92
0.10
1.72%
CRGO
Freightos Limited
3.10
1.50
93.75%
FLX
BingEx Ltd. ADR
3.11
-13.38
-81.14%

CryoPort Corporate Events

M&A TransactionsBusiness Operations and Strategy
CryoPort Sells CRYOPDP Business to DHL Group
Positive
Jun 13, 2025

On June 11, 2025, Cryoport, Inc. completed the divestiture of its CRYOPDP Business to DHL Group for approximately $200 million, as part of a strategic move to enhance its core capabilities and focus on the rapidly growing regenerative medicine market. This transaction, along with a newly formed strategic partnership with DHL, is expected to strengthen Cryoport’s positioning in the Asia Pacific and EMEA regions, offering enhanced supply chain services and contributing to the company’s long-term profitability goals.

The most recent analyst rating on (CYRX) stock is a Buy with a $15.00 price target. To see the full list of analyst forecasts on CryoPort stock, see the CYRX Stock Forecast page.

Executive/Board ChangesShareholder Meetings
CryoPort Holds 2025 Annual Stockholders Meeting
Neutral
Jun 10, 2025

On June 6, 2025, Cryoport, Inc. held its 2025 Annual Meeting of Stockholders, where several key proposals were voted on. The election of directors resulted in the appointment of six individuals to serve until the 2026 Annual Meeting. Additionally, the appointment of Deloitte and Touche LLP as the independent registered public accounting firm was ratified. Stockholders also approved the compensation of the company’s named executive officers and decided to hold an advisory vote on this compensation annually.

The most recent analyst rating on (CYRX) stock is a Buy with a $15.00 price target. To see the full list of analyst forecasts on CryoPort stock, see the CYRX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 07, 2025