tiprankstipranks
Trending News
More News >
Corbus Pharmaceuticals (CRBP)
NASDAQ:CRBP

Corbus Pharmaceuticals (CRBP) AI Stock Analysis

Compare
2,515 Followers

Top Page

CRBP

Corbus Pharmaceuticals

(NASDAQ:CRBP)

Select Model
Select Model
Select Model
Neutral 49 (OpenAI - 5.2)
Rating:49Neutral
Price Target:
$8.50
▲(4.04% Upside)
The score is held back primarily by weak financial performance (no revenue, sizable losses and cash burn) and bearish technical signals (below major moving averages with negative MACD). Offsetting factors include a low-debt balance sheet and positive recent corporate events around pipeline progress and financing that may improve operating runway into upcoming clinical milestones.
Positive Factors
Strong cash runway
A multi-year cash runway materially reduces short-term financing pressure and allows management to advance registrational studies and mid-2026 readouts without immediate dilution, improving the firm's ability to hit clinical milestones and negotiate partnerships from a position of strength.
CRB-701 regulatory progress
Fast Track status and encouraging ESMO data de-risk development timing and regulatory engagement. This supports a clearer path to registrational trials, faster review prospects, and potential competitive differentiation for a next-generation ADC in high Nectin-4 tumors.
Diversified pipeline with near-term catalysts
Multiple advancing programs (CRB-701, CRB-913, CRB-601) reduce binary outcome risk. Staggered clinical milestones across oncology and metabolic indications provide repeated opportunity to validate technology, attract partners, and build long-term value beyond any single trial result.
Negative Factors
No revenue and persistent losses
Sustained negative earnings and high cash burn reflect inherent biotech development risk: absent product revenue, the company depends on financing or partnerships to fund R&D. This structurally increases dilution risk and makes long-term sustainability contingent on clinical success or deal-making.
Reliance on equity financing
Recurrent capital raises underline structural dependence on external funding. While proceeds extend runway, ongoing development-stage cash needs mean future financings or partner deals are likely, creating dilution and execution risk if clinical readouts underperform or markets tighten.
Small operating scale and no commercial infrastructure
A very small team and lack of commercial operations limit internal capacity to scale products or launch independently. Long-term success will likely depend on external partnerships or building significant organizational capability, which requires time and capital and raises execution risk.

Corbus Pharmaceuticals (CRBP) vs. SPDR S&P 500 ETF (SPY)

Corbus Pharmaceuticals Business Overview & Revenue Model

Company DescriptionCorbus Pharmaceuticals Holdings, Inc., a biopharmaceutical company, focuses on the development of immune modulators for immuno-oncology and fibrosis diseases. It develops lenabasum, an oral molecule that selectively activates cannabinoid receptor type 2 (CB2), which is in Phase II clinical trial to treat systemic lupus erythematosus; CRB-601, an anti-integrin monoclonal antibody (mAb) for the treatment of cancer and fibrosis that inhibits the activation of transforming growth factor ß (TGFß); and CRB-602, an anti-avß6/avß8 mAb that blocks the activation of TGFß for the treatment of fibrotic diseases. The company is also developing cannabinoid receptor type 1 inverse agonist program for the treatment of metabolic disorders, such as obesity, diabetic nephropathy, diabetic retinopathy, and nonalcoholic steatohepatitis; fibrotic diseases, including lung, cardiac, renal disease, and liver fibrosis; and other diseases comprising ascites, cognitive defects, Prader-Willi syndrome, and smoking cessation. It has a licensing agreement with Jenrin Discovery, LLC to develop and commercialize the licensed products, including the Jenrin library of approximately 600 compounds, and multiple issued and pending patent filings. The company was incorporated in 2009 and is based in Norwood, Massachusetts.
How the Company Makes MoneyCorbus Pharmaceuticals primarily makes money through the development and commercialization of its drug candidates. The company's revenue model involves advancing its drug pipeline through clinical trials, obtaining regulatory approvals, and subsequently partnering with larger pharmaceutical companies for distribution and commercialization. Key revenue streams include milestone payments from strategic partnerships, licensing agreements, and potential sales of its proprietary drugs once approved. Corbus relies on collaborations with other pharmaceutical companies and research institutions to enhance its research capabilities and expedite the development of its therapeutic candidates, which is crucial for generating future revenue.

Corbus Pharmaceuticals Financial Statement Overview

Summary
Corbus Pharmaceuticals faces severe financial challenges with no revenue in recent periods, high net losses, and cash flow issues. The balance sheet shows some recovery in equity, but financial instability remains a risk. Strategic changes are essential for financial health improvement.
Income Statement
14
Very Negative
Corbus Pharmaceuticals has faced significant revenue challenges, with zero revenue in recent years and declining gross profit margins. The company's net losses have been substantial, indicating ongoing operational struggles. While total revenue was positive in 2019, it has since dropped to zero, highlighting critical revenue generation issues.
Balance Sheet
60
Neutral
The company's financial stability is concerning, with a significant debt load relative to equity, although the debt-to-equity ratio improved in 2024 due to positive equity. The equity ratio shows weak equity backing, but the positive stockholders' equity in 2024 is a recovery sign from previous negative equity.
Cash Flow
22
Negative
Corbus Pharmaceuticals has consistently experienced negative operating and free cash flows, indicating cash burn without adequate inflows from operations. The free cash flow to net income ratio is negative, reflecting inefficient cash usage. However, financing inflows in 2024 improved cash positions, providing temporary relief.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.00881.71K3.94M
Gross Profit-15.89M-600.00K0.00-1.49M-757.53K3.94M
EBITDA-68.87M-37.74M-40.10M-38.73M-54.35M-121.12M
Net Income-67.51M-40.21M-44.60M-55.83M-45.55M-111.27M
Balance Sheet
Total Assets109.51M155.88M28.27M66.31M107.73M102.29M
Cash, Cash Equivalents and Short-Term Investments26.98M149.06M20.91M59.20M97.65M85.43M
Total Debt2.05M3.24M20.89M25.09M26.59M26.84M
Total Liabilities17.37M13.45M35.18M33.32M38.62M57.02M
Stockholders Equity92.15M142.43M-6.91M32.99M69.11M45.27M
Cash Flow
Free Cash Flow-59.51M-41.79M-36.10M-37.56M-48.24M-100.17M
Operating Cash Flow-59.51M-41.79M-36.10M-37.54M-48.18M-99.69M
Investing Cash Flow64.23M-121.31M35.64M30.07M-73.42M-484.49K
Financing Cash Flow2.84M166.58M-2.82M-533.62K60.82M154.87M

Corbus Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Negative
Last Price8.17
Price Trends
50DMA
9.73
Negative
100DMA
11.46
Negative
200DMA
9.65
Negative
Market Momentum
MACD
-0.52
Negative
RSI
39.37
Neutral
STOCH
49.33
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CRBP, the sentiment is Negative. The current price of 8.17 is above the 20-day moving average (MA) of 8.16, below the 50-day MA of 9.73, and below the 200-day MA of 9.65, indicating a neutral trend. The MACD of -0.52 indicates Negative momentum. The RSI at 39.37 is Neutral, neither overbought nor oversold. The STOCH value of 49.33 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CRBP.

Corbus Pharmaceuticals Risk Analysis

Corbus Pharmaceuticals disclosed 51 risk factors in its most recent earnings report. Corbus Pharmaceuticals reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Corbus Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$114.54M-0.58-209.00%40.22%
49
Neutral
$144.99M-1.48-55.65%-17.43%
49
Neutral
$68.10M-1.02-76.44%-10.03%11.06%
45
Neutral
$77.76M-2.47-48.89%-9.42%
42
Neutral
$103.86M-0.97-85.44%-505.96%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CRBP
Corbus Pharmaceuticals
8.17
-4.95
-37.73%
SAVA
Cassava Sciences
2.13
-0.56
-20.82%
ATOS
Atossa Therapeutics
0.58
-0.27
-31.76%
BMEA
Biomea Fusion
1.40
-2.66
-65.64%
TCRX
TScan Therapeutics
1.14
-1.32
-53.66%

Corbus Pharmaceuticals Corporate Events

Business Operations and StrategyProduct-Related Announcements
Corbus Updates Corporate Outlook, Highlights Diversified 2026 Pipeline
Positive
Jan 12, 2026

On January 12, 2026, Corbus Pharmaceuticals updated its corporate presentation to highlight a diversified pipeline and key clinical milestones expected in 2026, underpinned by $173 million in cash, cash equivalents and investments as of November 3, 2025 and a relatively low share count of about 17.6 million common shares outstanding. The materials emphasize CRB-701 as a potentially best-in-class Nectin-4 antibody-drug conjugate with a proprietary design that delivers longer half-life, lower free MMAE exposure and a more convenient dosing regimen than current Nectin-4/MMAE competitors, alongside emerging safety data from a 167-patient dataset presented at ESMO 2025 showing lower rates of high-grade adverse events and peripheral neuropathy versus peer agents, positioning the drug to target high Nectin-4–expressing tumors such as head and neck, cervical and urothelial cancers. Corbus also outlines a 12-week, 240-patient mid-2026 obesity readout for CRB-913 and dose-escalation progress for CRB-601 in αvβ8-enriched solid tumors, signaling an active clinical year that could be pivotal for validating its oncology and metabolic franchises and strengthening its competitive standing in the ADC and obesity drug markets.

The most recent analyst rating on (CRBP) stock is a Hold with a $8.00 price target. To see the full list of analyst forecasts on Corbus Pharmaceuticals stock, see the CRBP Stock Forecast page.

Executive/Board Changes
Corbus Pharmaceuticals Announces Retirement of Board Member Holmer
Neutral
Dec 18, 2025

On December 12, 2025, Corbus Pharmaceuticals Holdings, Inc. announced that board member Alan Holmer notified the company of his decision to retire and will resign from its Board of Directors effective December 31, 2025. The company stated that Holmer’s departure was not due to any disagreement over its operations, policies, or practices, suggesting an orderly governance transition with no underlying operational or strategic dispute signaled to stakeholders.

The most recent analyst rating on (CRBP) stock is a Buy with a $53.00 price target. To see the full list of analyst forecasts on Corbus Pharmaceuticals stock, see the CRBP Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Corbus Pharmaceuticals Advances Obesity Treatment with CRB-913
Positive
Dec 11, 2025

On December 11, 2025, Corbus Pharmaceuticals announced the completion of its Phase 1a study of CRB-913, an oral CB1 inverse agonist for obesity management, and the initiation of a Phase 1b study expected to conclude in summer 2026. The Phase 1a study demonstrated that CRB-913 was safe, well-tolerated, and effective in promoting weight loss, with no serious adverse events reported, marking a significant step forward in Corbus’ obesity treatment research.

The most recent analyst rating on (CRBP) stock is a Buy with a $39.00 price target. To see the full list of analyst forecasts on Corbus Pharmaceuticals stock, see the CRBP Stock Forecast page.

Business Operations and StrategyFinancial DisclosuresPrivate Placements and Financing
Corbus Pharmaceuticals Completes $75 Million Public Offering
Positive
Nov 12, 2025

Corbus Pharmaceuticals reported its third quarter 2025 financial results, highlighting significant progress in its clinical programs. The company presented promising data for CRB-701 at ESMO 2025, with plans to start a registrational study in mid-2026. Additionally, Corbus completed a $75 million public offering, extending its cash runway into 2028, and is on track to advance its CRB-913 program for obesity treatment by the end of 2025. The financial results showed an increased net loss due to higher clinical development expenses, but the company’s strong cash position supports its operations and future plans.

The most recent analyst rating on (CRBP) stock is a Buy with a $39.00 price target. To see the full list of analyst forecasts on Corbus Pharmaceuticals stock, see the CRBP Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
Corbus Pharmaceuticals Announces $70.5M Public Offering
Neutral
Nov 3, 2025

On October 30, 2025, Corbus Pharmaceuticals announced an underwritten public offering of common stock and pre-funded warrants, aiming to raise approximately $70.5 million. The proceeds are intended to fund clinical development and general corporate purposes. The offering, managed by Jefferies and Piper Sandler, is expected to close around November 3, 2025, subject to customary conditions. This move is part of Corbus’ strategy to strengthen its financial position and advance its pipeline in the competitive oncology and obesity sectors.

The most recent analyst rating on (CRBP) stock is a Buy with a $39.00 price target. To see the full list of analyst forecasts on Corbus Pharmaceuticals stock, see the CRBP Stock Forecast page.

Financial Disclosures
Corbus Pharmaceuticals Announces Preliminary Q3 Financials
Neutral
Oct 30, 2025

Corbus Pharmaceuticals Holdings, Inc. announced preliminary financial information for the quarter ended September 30, 2025, estimating cash, cash equivalents, and investments at approximately $104.0 million. This figure includes $27.0 million in cash and cash equivalents. The company emphasized that these figures are preliminary and subject to change following financial closing procedures, and stakeholders should not place undue reliance on these estimates.

The most recent analyst rating on (CRBP) stock is a Buy with a $39.00 price target. To see the full list of analyst forecasts on Corbus Pharmaceuticals stock, see the CRBP Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Corbus Pharmaceuticals Presents Promising CRB-701 Study Results
Positive
Oct 20, 2025

On October 18, 2025, Corbus Pharmaceuticals announced data from its Phase 1/2 clinical study of CRB-701, presented at the 2025 European Society for Medical Oncology Congress. The study, involving 167 patients with various tumor types, demonstrated promising efficacy and a favorable safety profile, with no dose-limiting toxicities and low discontinuation rates. The results suggest potential differentiation from other experimental agents in head and neck squamous cell carcinoma (HNSCC) and cervical cancers, highlighting a significant unmet need in these areas. Corbus plans to initiate registrational studies by mid-2026, aiming to further develop CRB-701 as a treatment option for patients with advanced solid tumors.

The most recent analyst rating on (CRBP) stock is a Buy with a $51.00 price target. To see the full list of analyst forecasts on Corbus Pharmaceuticals stock, see the CRBP Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 12, 2026