Distribution ChallengesThe departure of Optime Care, the exclusive distributor for Korlym, has delayed Corcept's strategy to have at least two pharmacies operational, affecting near-term sales projections.
Generic CompetitionKorlym's generic pressure from Teva could kick in next year; we also see unfavorable regulatory outcomes for ongoing litigation cases, adding additional pressure.
Regulatory ChallengesThe FDA issued a Complete Response Letter requiring additional confirmatory evidence for relacorilant, which suggests a potential delay in its approval process.