Axsome Therapeutics Inc (AXSM)
NASDAQ:AXSM
Want to see AXSM full AI Analyst Report?
AXSM Stock Chart & Stats
$188.99
-$0.23(-0.27%)
At close: 4:00 PM EST
$188.99
-$0.23(-0.27%)
Day’s Range― - ―
52-Week Range$96.09 - $234.29
Previous CloseN/A
Volume140.83K
Average Volume (3M)576.44K
Market Cap
$11.19B
Enterprise Value$11.10B
Total Cash (Recent Filing)$305.11M
Total Debt (Recent Filing)$216.71M
Price to Earnings (P/E)―
Beta0.80
Next Earnings
Aug 10, 2026EPS Estimate
-0.84Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-3.73
Shares Outstanding51,459,766
10 Day Avg. Volume589,851
30 Day Avg. Volume576,436
Financial Highlights & Ratios
PEG Ratio1.29
Price to Book (P/B)102.90
Price to Sales (P/S)14.23
P/FCF Ratio-96.78
Enterprise Value/Market Cap0.99
Enterprise Value/Revenue15.67
Enterprise Value/Gross Profit16.92
Enterprise Value/Ebitda-64.25
Forecast
1Y Price Target
$261.88Price Target Upside38.57% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering19
EPS Forecast (FY)-1.91
Revenue Forecast (FY)$983.80M
Bulls Say, Bears Say
Bulls Say
Clinical Safety And EfficacyAXS-05 showed consistent benefit across pivotal studies with a favorable safety profile—no deaths reported and fewer serious adverse events than the current approved therapy—supporting broader clinician adoption.
Pipeline DiversificationCompany acquisition of worldwide rights to a neuropsychiatry asset plus a portfolio of five product candidates across multiple indications reduces single-product risk and creates additional potential revenue drivers.
Regulatory CatalystAnalyst notes that a label expansion filing for treatment of agitation in Alzheimer’s disease is under regulatory review and that positive pivotal data and precedent support a favorable approval outcome, which could materially expand the drug’s market opportunity.
Bears Say
Development And Efficacy RiskThe previously developed asset was not advanced by its prior owner after failing to demonstrate efficacy comparable to existing antipsychotics, signaling potential regulatory and clinical setbacks for the program.
Financial And Early Commercial PressureHigher-than-expected operating expenses combined with heavy deductions from copay assistance on a newly launched product are constraining near-term profitability and limiting initial revenue contribution.
Limited TransparencyAn investor event closed to the media restricts public visibility and could hinder investor ability to assess company developments and management plans.
Axsome Therapeutics News
AXSM FAQ
What was Axsome Therapeutics Inc’s price range in the past 12 months?
Axsome Therapeutics Inc lowest stock price was $96.09 and its highest was $234.29 in the past 12 months.
What is Axsome Therapeutics Inc’s market cap?
Axsome Therapeutics Inc’s market cap is $11.19B.
When is Axsome Therapeutics Inc’s upcoming earnings report date?
Axsome Therapeutics Inc’s upcoming earnings report date is Aug 10, 2026 which is in 90 days.
How were Axsome Therapeutics Inc’s earnings last quarter?
Axsome Therapeutics Inc released its earnings results on May 04, 2026. The company reported -$1.26 earnings per share for the quarter, missing the consensus estimate of -$0.844 by -$0.416.
Is Axsome Therapeutics Inc overvalued?
According to Wall Street analysts Axsome Therapeutics Inc’s price is currently Undervalued.
Does Axsome Therapeutics Inc pay dividends?
Axsome Therapeutics Inc does not currently pay dividends.
What is Axsome Therapeutics Inc’s EPS estimate?
Axsome Therapeutics Inc’s EPS estimate is -0.84.
How many shares outstanding does Axsome Therapeutics Inc have?
Axsome Therapeutics Inc has 51,459,766 shares outstanding.
What happened to Axsome Therapeutics Inc’s price movement after its last earnings report?
Axsome Therapeutics Inc reported an EPS of -$1.26 in its last earnings report, missing expectations of -$0.844. Following the earnings report the stock price went up 8.314%.
Which hedge fund is a major shareholder of Axsome Therapeutics Inc?
Currently, no hedge funds are holding shares in AXSM
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Axsome Therapeutics Stock Smart Score
Outperform
1
2
3
4
5
6
7
8
9
10
Analyst Consensus
Strong Buy
Average Price Target:
$261.88 (38.57% Upside)
$261.88 (38.57% Upside)
Blogger Sentiment
Bullish
AXSM Sentiment 80%
Sector Average 72%
Sector Average 72%
Hedge Fund Trend
Decreased
By 1.0M Shares
Last Quarter.
Last Quarter.
Crowd Wisdom
Neutral
Last 7 Days ▲ 0.3%
Last 30 Days ▲ 0.1%
Last 30 Days ▲ 0.1%
Technicals
SMA
Positive
20 days / 200 days
Momentum
80.92%
12-Months-Change
Fundamentals
Return on Equity
-260.01%
Trailing 12-Months
Asset Growth
19.60%
Trailing 12-Months
Company Description
Axsome Therapeutics Inc
Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's product pipeline includes AXS-05, a therapeutic for the treatment of major depressive disorder and resistant depression disorders; and that is in the Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation. It is also developing AXS-07, a novel, oral, rapidly absorbed, multi-mechanistic, and investigational medicine that has completed two Phase III trials for the acute treatment of migraine; AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is in Phase III trial to treat narcolepsy; and AXS-14, a novel, oral, and investigational medicine that is in Phase III trial for the treatment of fibromyalgia. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.
AXSM Company Deck
AXSM Earnings Call
Q1 2026
0:00 / 0:00
Earnings Call Sentiment|Positive
The call conveys strong commercial momentum and multiple material positive milestones: 57% YoY revenue growth, AUVELITY's new FDA approval and upgraded $8B peak-sales outlook, sales-force expansions, meaningful payer wins, and an advancing late-stage pipeline with recent BD adding AXS-20. Offsetting risks include materially higher SG&A, elevated gross-to-net discounts (notably for SYMBRAVO), a modest widening of net loss, a slight decline in cash, and remaining clinical/regulatory uncertainties for several pipeline assets. On balance, the positives (robust revenue growth, regulatory wins, and clear commercial execution) significantly outweigh the near-term financial and access headwinds.View all AXSM earnings summariesAXSM Stock 12 Month Forecast
Average Price Target
$261.88
▲(38.57% Upside)
Technical Analysis
Cytokinetics
―
Rhythm Pharmaceuticals
―
Legend Biotech
―
Atrium Therapeutics, Inc.
―
Nuvalent
―
Ownership Overview
15.38% Insiders
24.42% Mutual Funds
4.15% Other Institutional Investors
42.05% Public Companies and
Individual Investors