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AXSM Stock Chart & Stats
$241.00
-$0.53(-0.22%)
At close: 4:00 PM EDT
$241.00
-$0.53(-0.22%)
Day’s Range― - ―
52-Week Range$104.15 - $260.19
Previous CloseN/A
Volume461.99K
Average Volume (3M)1.02M
Market Cap
$11.30B
Enterprise Value$12.58K
Total Cash (Recent Filing)$319.85M
Total Debt (Recent Filing)$219.21M
Price to Earnings (P/E)―
Beta0.75
Next Earnings
Nov 09, 2026EPS Estimate
-0.47Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-3.75
Shares Outstanding52,380,817
10 Day Avg. Volume706,319
30 Day Avg. Volume1,019,090
Financial Highlights & Ratios
PEG Ratio1.29
Price to Book (P/B)102.90
Price to Sales (P/S)14.23
P/FCF Ratio-96.78
Enterprise Value/Market Cap<0.01
Enterprise Value/Revenue<0.01
Enterprise Value/Gross Profit<0.01
Enterprise Value/Ebitda>-0.01
Forecast
1Y Price Target
$291.00Price Target Upside20.75% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering13
EPS Forecast (FY)-2.61
Revenue Forecast (FY)$964.38M
Bulls Say, Bears Say
Bulls Say
Revenue Growth & Gross MarginAxsome has scaled U.S. product sales rapidly and generates very high product margins (~93% TTM). That structural margin profile gives durable operating leverage: as commercial scale continues, high gross profitability can fund R&D and commercialization and accelerate the path to sustained operating profitability.
AUVELITY Alzheimer's ApprovalThe new AUVELITY approval for agitation in Alzheimer's is a first‑in‑class, high‑unmet‑need indication that expands addressable market and extends product lifecycle. Durable regulatory labeling with payer uptake supports long‑term prescription volume and revenue diversification beyond MDD.
Deep Late‑stage CNS PipelineA broad, late‑stage CNS portfolio (six candidates, an AXS‑12 NDA and multiple upcoming Phase III programs) provides multi‑year optionality. Successful approvals would create new revenue streams, reduce single‑product concentration risk and sustain growth even if individual trials face delays.
Bears Say
Negative Operating & Free Cash FlowAxsome remains cash‑consumptive with negative operating and free cash flow (TTM ~ -$71M). Although cash burn has narrowed, persistent negative FCF forces reliance on financing until margins or revenue convert to sustained positive cash generation, limiting strategic flexibility and increasing dilution/refinancing risk.
High Leverage / Thin EquitySignificant leverage (debt ~$219M, debt/equity ~2.63) and relatively thin equity amplify financial risk. High leverage raises interest and refinancing exposure, constrains the company's ability to fund M&A or additional spend, and magnifies downside for shareholders until consistent profitability rebuilds equity cushions.
High Gross-to-net & Rising SG&AMaterial gross‑to‑net discounts (low‑mid 50% for AUVELITY/SUNOSI; high‑70% for SYMBRAVO) directly reduce realized revenue and margins. Combined with a substantial SG&A increase to $185M for sales force expansion and DTC, these structural cost and pricing pressures delay conversion of top‑line growth into sustainable operating profits.
Axsome Therapeutics News
AXSM FAQ
What was Axsome Therapeutics Inc’s price range in the past 12 months?
Axsome Therapeutics Inc lowest stock price was $104.15 and its highest was $260.19 in the past 12 months.
What is Axsome Therapeutics Inc’s market cap?
Axsome Therapeutics Inc’s market cap is $11.30B.
When is Axsome Therapeutics Inc’s upcoming earnings report date?
Axsome Therapeutics Inc’s upcoming earnings report date is Nov 09, 2026 which is in 88 days.
How were Axsome Therapeutics Inc’s earnings last quarter?
Axsome Therapeutics Inc released its earnings results on Aug 10, 2026. The company reported -$0.99 earnings per share for the quarter, missing the consensus estimate of -$0.892 by -$0.098.
Is Axsome Therapeutics Inc overvalued?
According to Wall Street analysts Axsome Therapeutics Inc’s price is currently Undervalued.
Does Axsome Therapeutics Inc pay dividends?
Axsome Therapeutics Inc does not currently pay dividends.
What is Axsome Therapeutics Inc’s EPS estimate?
Axsome Therapeutics Inc’s EPS estimate is -0.47.
How many shares outstanding does Axsome Therapeutics Inc have?
Axsome Therapeutics Inc has 52,380,817 shares outstanding.
What happened to Axsome Therapeutics Inc’s price movement after its last earnings report?
Axsome Therapeutics Inc reported an EPS of -$0.99 in its last earnings report, missing expectations of -$0.892. Following the earnings report the stock price went up 3.831%.
Which hedge fund is a major shareholder of Axsome Therapeutics Inc?
Currently, no hedge funds are holding shares in AXSM
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Axsome Therapeutics Stock Smart Score
Outperform
1
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5
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7
8
9
10
Analyst Consensus
Strong Buy
Average Price Target:
$291.00 (20.75% Upside)
$291.00 (20.75% Upside)
Blogger Sentiment
Bullish
AXSM Sentiment 75%
Sector Average 61%
Sector Average 61%
Hedge Fund Trend
Increased
By 92.1K Shares
Last Quarter.
Last Quarter.
Crowd Wisdom
Positive
Last 7 Days ▼ 0.1%
Last 30 Days ▲ 1.7%
Last 30 Days ▲ 1.7%
News Sentiment
Very Bullish
Bullish news 100%
Bearish news 0%
Bearish news 0%
Technicals
SMA
Positive
20 days / 200 days
Momentum
129.58%
12-Months-Change
Fundamentals
Return on Equity
―
Trailing 12-Months
Asset Growth
19.02%
Trailing 12-Months
Company Description
Axsome Therapeutics Inc
Axsome Therapeutics, Inc. is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for a range of central nervous system (CNS) disorders within the United States. Its robust product pipeline features several promising candidates, including: AXS-05, an investigational therapy currently being developed for major depressive disorder and treatment-resistant depression. This compound is also in Phase III clinical evaluation for Alzheimer's disease agitation and has successfully finished Phase II trials investigating its use for smoking cessation. AXS-07, a novel, orally administered, rapidly-acting investigational medicine that employs multiple mechanisms of action. It has concluded two Phase III studies for the acute treatment of migraine attacks. AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is presently undergoing a Phase III trial for narcolepsy. AXS-14, an oral investigational drug, advancing through Phase III trials for the management of fibromyalgia. Axsome Therapeutics also engages in a research collaboration with Duke University to further assess AXS-05's potential in smoking cessation. The company, established in 2012, has its main offices in New York, New York.
AXSM Company Deck
AXSM Earnings Call
Q2 2026
0:00 / 0:00
Earnings Call Sentiment|Positive
The call conveys strong commercial momentum and multiple material positive milestones: 57% YoY revenue growth, AUVELITY's new FDA approval and upgraded $8B peak-sales outlook, sales-force expansions, meaningful payer wins, and an advancing late-stage pipeline with recent BD adding AXS-20. Offsetting risks include materially higher SG&A, elevated gross-to-net discounts (notably for SYMBRAVO), a modest widening of net loss, a slight decline in cash, and remaining clinical/regulatory uncertainties for several pipeline assets. On balance, the positives (robust revenue growth, regulatory wins, and clear commercial execution) significantly outweigh the near-term financial and access headwinds.View all AXSM earnings summariesAXSM Stock 12 Month Forecast
All Analysts
Top Analysts
Average Price Target
$291.00
▲(20.75% Upside)
Technical Analysis
1 Day
3 Days
1 Week
1 Month
Ownership Overview
15.08% Insiders
24.67% Mutual Funds
3.93% Other Institutional Investors
43.44% Public Companies and Individual Investors













