Clinical Adoption RiskUncertainty about long‑term durability of responses could limit physician adoption and constrain commercial uptake even if initial efficacy and safety data look favorable.
Event-driven VolatilityThe added pivotal trial readout concentrates event-driven risk, so disappointing results could trigger sharp share declines and heightened market volatility.
Financing RiskEstimated cash burn relative to available cash points to potential financing pressure if clinical or commercial progress is slower than expected, increasing dilution risk for shareholders.