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Cidara Therapeutics (CDTX)
NASDAQ:CDTX
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Cidara Therapeutics (CDTX) AI Stock Analysis

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CDTX

Cidara Therapeutics

(NASDAQ:CDTX)

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Neutral 55 (OpenAI - 4o)
Rating:55Neutral
Price Target:
$102.00
▲(2.02% Upside)
Cidara Therapeutics' overall score is primarily impacted by its challenging financial performance, with persistent losses and reliance on external financing. However, the positive earnings call, highlighting successful clinical trials and strong financial backing, provides a significant boost. The technical analysis suggests a bullish trend, but the valuation remains a concern due to the negative P/E ratio and non-revenue generating status.
Positive Factors
Regulatory Advancements
The Breakthrough Therapy designation for CD388 by the FDA signifies potential for accelerated development and review, enhancing CDTX's competitive position in the influenza prevention market.
Strong Financial Backing
The substantial financial backing provides Cidara with the necessary resources to advance its clinical trials and development programs, supporting long-term growth and innovation.
Strategic Partnerships
The BARDA award supports CD388's development and manufacturing, indicating strong government partnership and potential for expanded market reach, enhancing CDTX's strategic position.
Negative Factors
Non-Revenue Generating Status
The lack of revenue generation poses financial risks, as the company remains reliant on external funding, impacting its ability to achieve sustainable profitability in the near term.
Negative Cash Flow
Persistent negative cash flow indicates operational inefficiencies and a heavy reliance on external financing, challenging the company's long-term financial sustainability.
Potential Delays in Phase III Study
Delays in the Phase III study could postpone product commercialization, affecting revenue timelines and investor confidence in the company's growth prospects.

Cidara Therapeutics (CDTX) vs. SPDR S&P 500 ETF (SPY)

Cidara Therapeutics Business Overview & Revenue Model

Company DescriptionCidara Therapeutics (CDTX) is a biotechnology company focused on the development of novel therapeutics for the treatment of fungal infections and other serious diseases. The company operates primarily in the biotechnology sector, leveraging its innovative platform to design and develop new medicines that address unmet medical needs. Cidara's core products include its lead candidate, rezafungin, an antifungal agent aimed at treating invasive fungal infections, and its Cloudbreak platform, which is designed for the development of combination therapies.
How the Company Makes MoneyCidara Therapeutics generates revenue primarily through the development and commercialization of its drug candidates. The company likely makes money through milestone payments from partnerships with larger pharmaceutical companies, licensing agreements, and potential royalties from product sales once their therapies are approved and marketed. Significant partnerships with established pharmaceutical firms for co-development or distribution of its products can also contribute to revenue, along with government grants and funding aimed at supporting research and development efforts.

Cidara Therapeutics Earnings Call Summary

Earnings Call Date:Aug 07, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Nov 06, 2025
Earnings Call Sentiment Positive
The earnings call reflects a strong positive outlook for Cidara Therapeutics due to successful clinical trial results, significant financial backing, and advancing regulatory discussions. However, challenges remain due to the company's non-revenue generating status and potential delays in Phase III study commencement.
Q2-2025 Updates
Positive Updates
Positive Phase IIb NAVIGATE Clinical Trial Results
Cidara Therapeutics announced positive top line results from its Phase IIb NAVIGATE clinical trial, demonstrating statistically significant efficacy of CD388 with 76%, 61%, and 58% protection rates at 450mg, 300mg, and 150mg doses respectively, all with p-values indicating strong statistical significance compared to placebo.
$400 Million Financing Secured
Cidara secured $400 million in financing, providing a strong financial position to fund the completion of the planned Phase III study and additional supportive clinical and nonclinical studies.
Potential FDA and BARDA Support
Cidara advanced discussions with the FDA for Phase III development and submitted a proposal to BARDA which, if funded, could provide significant support for manufacturing and clinical development of CD388.
Fast Track and Priority Review Designations
CD388 has received Fast Track and Priority Review designations from the FDA, and an application for Breakthrough Therapy Designation has been submitted.
Negative Updates
Non-Revenue Generating Status
Cidara is currently a non-revenue generating company, which could pose financial risks despite the recent financing.
Potential Delays in Phase III Study
The start of the Phase III study could be delayed depending on the outcome of the upcoming FDA meeting, with possible commencement only in the Southern Hemisphere spring of 2026.
Company Guidance
During the Cidara Therapeutics Second Quarter 2025 earnings call, significant progress was highlighted, particularly with the positive top-line results from the Phase IIb NAVIGATE clinical trial for CD388, which demonstrated 76%, 61%, and 58% protection in three different dose groups. The study enrolled over 5,000 subjects, and the observed placebo attack rate was 2.8%, allowing for statistically significant differences in efficacy with p-values of less than 0.0001, 0.0024, and 0.005 for the respective doses. Following these results, Cidara secured $400 million in financing and engaged in discussions with the FDA and BARDA, with plans to initiate a Phase III study in 2026. The company also emphasized CD388's potential as a universal preventative for influenza, supported by its current Fast Track and Priority Review designations. Cidara aims to target high-risk populations, including immune-compromised patients, in their upcoming Phase III study, backed by their strong financial position from a recent $402.5 million public offering.

Cidara Therapeutics Financial Statement Overview

Summary
Cidara Therapeutics faces significant financial challenges with persistent losses and negative cash flows. The company has a deeply negative net profit margin and relies heavily on external financing to sustain operations. Despite a low debt-to-equity ratio, the financial trajectory suggests a need for strategic improvements.
Income Statement
35
Negative
Cidara Therapeutics has experienced a significant revenue decline in the latest year, with a revenue growth rate of -98% from the previous year. The net profit margin is deeply negative, at -13362.04% for 2024, indicating substantial losses relative to revenue. The gross profit margin is also negative, suggesting that the company is selling below cost. While biotechnology companies often face high R&D expenses, the magnitude of losses is concerning.
Balance Sheet
40
Negative
The company's debt-to-equity ratio is low due to a relatively high stockholders' equity, indicating low leverage. However, the equity ratio is 76.02%, reflecting a stable capital structure. Despite this, the company has historically negative equity, raising concerns about sustainable financial health. The increase in cash reserves provides some liquidity cushion.
Cash Flow
45
Neutral
Operating cash flow is significantly negative, although there has been substantial cash inflow from financing activities. Free cash flow remains negative, and the operating cash flow to net income ratio is negative, due to both operating cash flow and net income being negative. The company is heavily dependent on external financing to sustain operations.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.001.27M63.91M64.29M49.57M12.07M
Gross Profit-90.78M-83.61M62.38M64.14M49.38M-55.95M
EBITDA-124.06M-176.10M-24.36M-33.36M-42.26M-71.56M
Net Income-91.32M-169.83M-22.93M-33.58M-42.47M-72.37M
Balance Sheet
Total Assets534.33M214.80M67.03M47.59M75.33M60.42M
Cash, Cash Equivalents and Short-Term Investments510.57M189.82M35.78M32.73M62.27M35.91M
Total Debt2.33M3.58M4.88M1.21M5.06M7.96M
Total Liabilities33.15M51.49M75.24M50.50M53.75M49.71M
Stockholders Equity501.17M163.31M-8.21M-2.90M21.57M10.71M
Cash Flow
Free Cash Flow-129.13M-176.66M-22.94M-28.59M-25.27M-54.60M
Operating Cash Flow-129.02M-176.53M-22.43M-28.47M-25.23M-54.41M
Investing Cash Flow79.00K-129.00K-505.00K-118.00K-41.00K-186.00K
Financing Cash Flow481.49M337.06M25.98M-951.00K44.60M37.28M

Cidara Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price99.98
Price Trends
50DMA
83.07
Positive
100DMA
66.59
Positive
200DMA
44.01
Positive
Market Momentum
MACD
4.59
Positive
RSI
59.62
Neutral
STOCH
37.55
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CDTX, the sentiment is Positive. The current price of 99.98 is below the 20-day moving average (MA) of 102.56, above the 50-day MA of 83.07, and above the 200-day MA of 44.01, indicating a bullish trend. The MACD of 4.59 indicates Positive momentum. The RSI at 59.62 is Neutral, neither overbought nor oversold. The STOCH value of 37.55 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CDTX.

Cidara Therapeutics Risk Analysis

Cidara Therapeutics disclosed 57 risk factors in its most recent earnings report. Cidara Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Cidara Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
$2.61B12.9628.49%28.55%196.96%
$2.79B-31.46%254.45%48.06%
$2.56B-35.09%-41.48%-73.55%
$2.67B-9.44-37.05%-100.00%55.31%
$2.41B-57.33%99.50%65.91%
$7.86B-0.30-43.30%2.27%22.53%-2.21%
$2.83B-41.94%-82.90%-155.64%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CDTX
Cidara Therapeutics
105.14
92.31
719.49%
CPRX
Catalyst Pharma
21.36
-0.20
-0.93%
IDYA
IDEAYA Biosciences
33.19
3.73
12.66%
ARQT
Arcutis Biotherapeutics
24.95
16.43
192.84%
BEAM
Beam Therapeutics
26.43
3.93
17.47%
TARS
Tarsus Pharmaceuticals
67.56
22.83
51.04%

Cidara Therapeutics Corporate Events

Cidara Therapeutics’ CD388 Study: A Potential Game-Changer in Influenza Prevention
Oct 27, 2025

Study Overview: Cidara Therapeutics Inc. is conducting a Phase 3 study titled A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Safety and Efficacy of CD388, a Novel Long-Acting Antiviral Conjugate, for the Prevention of Influenza in Adults and Adolescents at Higher Risk of Developing Influenza Complications. The study aims to assess the effectiveness of CD388 in preventing laboratory-confirmed influenza infections and its safety compared to a placebo.

Business Operations and StrategyProduct-Related Announcements
Cidara Therapeutics Expands Phase 3 Trial for CD388
Positive
Sep 25, 2025

On September 24, 2025, Cidara Therapeutics announced an update to its Phase 3 trial plan for CD388 following discussions with the FDA. The trial will now include a broader population, potentially increasing eligible patients in the U.S. from 50 million to over 100 million, and will begin enrollment by the end of September 2025, six months earlier than initially planned.

The most recent analyst rating on (CDTX) stock is a Buy with a $123.00 price target. To see the full list of analyst forecasts on Cidara Therapeutics stock, see the CDTX Stock Forecast page.

Cidara Therapeutics: Promising Trials Amidst Financial Challenges
Aug 13, 2025

Cidara Therapeutics Inc. recently held an earnings call that conveyed a mixed sentiment. On the positive side, the company reported significant progress in its clinical trials and financial positioning, highlighted by robust Phase IIb results and substantial financing. However, challenges such as the absence of revenue generation and potential impacts on study timelines due to lower attack rates in Phase III were also discussed, presenting some concerns.

Cidara Therapeutics Reports Positive Trial Results and Financial Growth
Aug 8, 2025

Cidara Therapeutics, Inc. is a biotechnology company based in San Diego, California, specializing in the development of drug-Fc conjugate (DFC) therapeutics using its proprietary Cloudbreak platform. The company focuses on creating innovative treatments for infectious diseases and oncology.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 28, 2025