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Cidara Therapeutics (CDTX)
NASDAQ:CDTX
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Cidara Therapeutics (CDTX) AI Stock Analysis

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CDTX

Cidara Therapeutics

(NASDAQ:CDTX)

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Neutral 57 (OpenAI - 4o)
Rating:57Neutral
Price Target:
$225.00
▲(2.73% Upside)
Cidara Therapeutics' overall stock score is driven by strong technical momentum, despite significant financial challenges and valuation concerns. The earnings call provided positive guidance on CD388's development, but manufacturing and enrollment risks remain.
Positive Factors
Strategic Acquisition
The acquisition by Merck provides Cidara with significant resources and stability, enhancing its ability to develop and commercialize its therapies, potentially accelerating growth and innovation.
FDA Breakthrough Designation
This designation can expedite the development and review process, potentially bringing CD388 to market faster, addressing unmet medical needs and enhancing Cidara's competitive position.
Strong Financial Position
A robust cash position ensures that Cidara can fund its Phase III program and other strategic initiatives without immediate financial strain, supporting long-term operational stability.
Negative Factors
Persistent Financial Losses
Ongoing financial losses and dependency on external funding highlight operational inefficiencies and pose risks to long-term sustainability if not addressed.
Negative Revenue Growth
A significant decline in revenue indicates challenges in product commercialization and market penetration, potentially affecting future growth prospects.
Manufacturing Challenges
Manufacturing bottlenecks could delay regulatory filings and market entry, impacting the company's ability to capitalize on its R&D investments and competitive edge.

Cidara Therapeutics (CDTX) vs. SPDR S&P 500 ETF (SPY)

Cidara Therapeutics Business Overview & Revenue Model

Company DescriptionCidara Therapeutics (CDTX) is a biotechnology company focused on the development of novel therapeutics for the treatment of fungal infections and other serious diseases. The company operates primarily in the biotechnology sector, leveraging its innovative platform to design and develop new medicines that address unmet medical needs. Cidara's core products include its lead candidate, rezafungin, an antifungal agent aimed at treating invasive fungal infections, and its Cloudbreak platform, which is designed for the development of combination therapies.
How the Company Makes MoneyCidara Therapeutics generates revenue primarily through the development and commercialization of its drug candidates. The company likely makes money through milestone payments from partnerships with larger pharmaceutical companies, licensing agreements, and potential royalties from product sales once their therapies are approved and marketed. Significant partnerships with established pharmaceutical firms for co-development or distribution of its products can also contribute to revenue, along with government grants and funding aimed at supporting research and development efforts.

Cidara Therapeutics Earnings Call Summary

Earnings Call Date:Nov 06, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 11, 2026
Earnings Call Sentiment Positive
The earnings call highlighted significant progress in the development and funding of CD388, along with strong financial positioning. However, there are challenges related to manufacturing scale-up and uncertainties in flu vaccination rates and study enrollment timing.
Q3-2025 Updates
Positive Updates
Accelerated Phase III Development of CD388
CD388 has advanced into Phase III development six months earlier than planned, with expanded patient population and FDA breakthrough therapy designation.
BARDA Funding Secured
Cidara received up to $339 million from BARDA to support CD388 manufacturing and clinical development, with $58 million for initial activities.
Strong Financial Position
Cidara has approximately $476 million in cash, fully funding the Phase III program through completion.
Positive Phase IIb Results
CD388's Phase IIb study met its primary endpoint with 76.1% protective efficacy, supporting Phase III dose selection.
Negative Updates
Potential Manufacturing Challenges
CMC processes are rate-limiting for BLA filing, requiring transition to a single vial configuration and full process characterization.
Uncertainty in Vaccine Uptake and Flu Rates
Flu vaccination rates and timing of influenza season can impact study enrollment and efficacy results.
Company Guidance
During the Cidara Therapeutics Q3 2025 Conference Call, the company provided detailed guidance on its lead candidate, CD388, which has advanced into Phase III development. The trial commenced six months earlier than planned, evaluating the drug's safety and efficacy in high-risk populations for influenza, with plans to enroll 6,000 participants across 150 sites. The study is over 50% enrolled and aims to complete Northern Hemisphere enrollment by December. The FDA granted CD388 breakthrough therapy designation, enhancing its regulatory pathway with potential priority review. The company secured $339 million from BARDA for expanded manufacturing and clinical development. Cidara holds approximately $476 million in cash, ensuring the Phase III program is fully funded. An interim analysis in Q1 2026 may influence further enrollment in the Southern Hemisphere. The company plans a virtual R&D Day on December 15 to update on CD388’s progress and commercial opportunities.

Cidara Therapeutics Financial Statement Overview

Summary
Cidara Therapeutics faces significant financial challenges with persistent losses and negative cash flows. The income statement reveals a drastic revenue decline and deeply negative profit margins. The balance sheet shows low leverage but historically negative equity, while cash flow is heavily reliant on external financing.
Income Statement
35
Negative
Cidara Therapeutics has experienced a significant revenue decline in the latest year, with a revenue growth rate of -98% from the previous year. The net profit margin is deeply negative, at -13362.04% for 2024, indicating substantial losses relative to revenue. The gross profit margin is also negative, suggesting that the company is selling below cost. While biotechnology companies often face high R&D expenses, the magnitude of losses is concerning.
Balance Sheet
40
Negative
The company's debt-to-equity ratio is low due to a relatively high stockholders' equity, indicating low leverage. However, the equity ratio is 76.02%, reflecting a stable capital structure. Despite this, the company has historically negative equity, raising concerns about sustainable financial health. The increase in cash reserves provides some liquidity cushion.
Cash Flow
45
Neutral
Operating cash flow is significantly negative, although there has been substantial cash inflow from financing activities. Free cash flow remains negative, and the operating cash flow to net income ratio is negative, due to both operating cash flow and net income being negative. The company is heavily dependent on external financing to sustain operations.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.001.27M23.28M64.45M49.57M12.07M
Gross Profit-45.00M1.27M-13.48M64.45M-23.52M12.07M
EBITDA-189.91M-175.87M-26.95M-33.36M-42.07M-70.80M
Net Income-184.74M-169.83M-22.93M-33.58M-42.47M-72.11M
Balance Sheet
Total Assets518.65M214.80M67.03M47.49M75.33M60.42M
Cash, Cash Equivalents and Short-Term Investments293.65M189.82M35.78M32.73M62.27M35.91M
Total Debt1.98M3.58M4.88M1.21M5.06M7.96M
Total Liabilities96.26M51.49M75.24M61.92M53.75M49.71M
Stockholders Equity422.39M163.31M-8.21M-14.44M21.57M10.71M
Cash Flow
Free Cash Flow-132.94M-176.66M-22.94M-28.59M-25.27M-54.60M
Operating Cash Flow-132.94M-176.53M-22.43M-28.47M-25.23M-54.41M
Investing Cash Flow-176.28M-129.00K-505.00K-118.00K-41.00K-186.00K
Financing Cash Flow481.83M337.06M25.98M-951.00K44.60M37.28M

Cidara Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price219.02
Price Trends
50DMA
108.03
Positive
100DMA
84.31
Positive
200DMA
54.02
Positive
Market Momentum
MACD
30.36
Negative
RSI
88.88
Negative
STOCH
99.47
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CDTX, the sentiment is Positive. The current price of 219.02 is above the 20-day moving average (MA) of 132.13, above the 50-day MA of 108.03, and above the 200-day MA of 54.02, indicating a bullish trend. The MACD of 30.36 indicates Negative momentum. The RSI at 88.88 is Negative, neither overbought nor oversold. The STOCH value of 99.47 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CDTX.

Cidara Therapeutics Risk Analysis

Cidara Therapeutics disclosed 57 risk factors in its most recent earnings report. Cidara Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Cidara Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
83
Outperform
$2.77B13.1427.52%25.56%44.42%
60
Neutral
$3.21B-28.17%129.21%80.35%
60
Neutral
$3.27B-28.35%182.44%47.21%
57
Neutral
$6.89B-68.70%-100.00%53.89%
56
Neutral
$2.90B-14.15%5376.27%20.97%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
40
Neutral
$2.13B-4.64-47.19%-84.07%-157.71%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CDTX
Cidara Therapeutics
219.55
202.10
1158.17%
CPRX
Catalyst Pharma
22.77
1.65
7.81%
IDYA
IDEAYA Biosciences
33.16
6.56
24.66%
ARQT
Arcutis Biotherapeutics
27.33
17.09
166.89%
BEAM
Beam Therapeutics
20.60
-2.98
-12.64%
TARS
Tarsus Pharmaceuticals
76.98
30.58
65.91%

Cidara Therapeutics Corporate Events

Business Operations and StrategyM&A Transactions
Cidara Therapeutics Enters Merger Agreement with Merck
Positive
Nov 14, 2025

On November 13, 2025, Cidara Therapeutics entered into a merger agreement with Merck, where Merck will acquire Cidara for $221.50 per share, totaling approximately $9.2 billion. This acquisition aims to diversify Merck’s portfolio by including Cidara’s investigational antiviral agent, CD388, which is currently in Phase 3 trials for preventing influenza in high-risk individuals. The merger is expected to close in the first quarter of 2026, pending regulatory approvals and other customary conditions. This strategic move aligns with Merck’s science-led business development strategy and is anticipated to enhance its pipeline, potentially driving growth and providing significant value to shareholders.

The most recent analyst rating on (CDTX) stock is a Hold with a $102.00 price target. To see the full list of analyst forecasts on Cidara Therapeutics stock, see the CDTX Stock Forecast page.

Cidara Therapeutics’ Earnings Call Highlights CD388 Progress
Nov 9, 2025

Cidara Therapeutics Inc. recently held its earnings call, revealing a generally optimistic sentiment with significant advancements in the development and funding of its lead candidate, CD388. The company demonstrated strong financial positioning, although it acknowledged challenges related to manufacturing scale-up and uncertainties in flu vaccination rates and study enrollment timing.

Cidara Therapeutics Advances CD388 with Phase 3 Expansion
Nov 7, 2025

Cidara Therapeutics, Inc., a biotechnology company based in San Diego, is focused on developing drug-Fc conjugate therapeutics using its proprietary Cloudbreak platform, with a lead candidate aimed at preventing influenza.

Cidara Therapeutics’ CD388 Study: A Potential Game-Changer in Influenza Prevention
Oct 27, 2025

Study Overview: Cidara Therapeutics Inc. is conducting a Phase 3 study titled A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Safety and Efficacy of CD388, a Novel Long-Acting Antiviral Conjugate, for the Prevention of Influenza in Adults and Adolescents at Higher Risk of Developing Influenza Complications. The study aims to assess the effectiveness of CD388 in preventing laboratory-confirmed influenza infections and its safety compared to a placebo.

Business Operations and StrategyProduct-Related Announcements
Cidara Therapeutics Expands Phase 3 Trial for CD388
Positive
Sep 25, 2025

On September 24, 2025, Cidara Therapeutics announced an update to its Phase 3 trial plan for CD388 following discussions with the FDA. The trial will now include a broader population, potentially increasing eligible patients in the U.S. from 50 million to over 100 million, and will begin enrollment by the end of September 2025, six months earlier than initially planned.

The most recent analyst rating on (CDTX) stock is a Buy with a $123.00 price target. To see the full list of analyst forecasts on Cidara Therapeutics stock, see the CDTX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 15, 2025