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BioStem Technologies (BSEM)
OTHER OTC:BSEM
US Market

BioStem Technologies (BSEM) AI Stock Analysis

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BSEM

BioStem Technologies

(OTC:BSEM)

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Neutral 68 (OpenAI - 5.2)
Rating:68Neutral
Price Target:
$6.00
▲(24.22% Upside)
Action:DowngradedDate:02/04/26
The score is primarily supported by strong profitability/cash generation and an inexpensive P/E valuation. Offsetting this are weakening revenue and cash-flow growth trends plus longer-term technical weakness versus the 200-day average, while the latest earnings call was constructive on execution but flagged ongoing pricing-driven revenue pressure and a lower cash balance.
Positive Factors
High profitability and cash generation
Sustained high gross margins and positive operating and free cash flow (FCF/net income ~0.98) indicate the business converts sales to cash efficiently. This durable cash generation supports ongoing R&D, working capital, and strategic investments without relying heavily on external financing.
Conservative capital structure
Very low leverage provides financial flexibility to fund expansion, absorb reimbursement or pricing shocks, and pursue strategic projects (e.g., facility investments, market entry) while keeping interest burden limited. It reduces refinancing risk over the medium term.
Operational resilience and regulated readiness
Consistent positive adjusted EBITDA across seven quarters, combined with a clean FDA inspection and active expansion into Medicaid and VA channels, demonstrates durable operational control and regulated-market readiness, supporting sustainable commercialization and longer-term revenue opportunities.
Negative Factors
Sustained revenue decline
Material year-over-year and sequential revenue declines point to structural top-line pressure driven by pricing/reimbursement shifts and competitive dynamics. Persistent revenue erosion can undermine scale economics, limit reinvestment capacity, and pressure long-term growth prospects.
Margin compression and falling ROE
A decline in gross margin alongside a notable drop in ROE suggests emerging margin pressure and reduced capital efficiency. If pricing and reimbursement headwinds persist, profit margins and returns on equity could continue to compress, weakening long-term profitability sustainability.
Slowing free cash flow growth and cash depletion
Declining FCF growth and a falling cash balance—partly due to strategic land acquisition and collection timing—reduce near-term liquidity cushions. Continued FCF deceleration would limit ability to fund expansion or absorb shocks without tapping reserves or raising capital.

BioStem Technologies (BSEM) vs. SPDR S&P 500 ETF (SPY)

BioStem Technologies Business Overview & Revenue Model

Company DescriptionBioStem Technologies, Inc., a life sciences corporation, focuses on discovering, developing, and producing pharmaceutical and regenerative medicine products and services. It develops various biologic stem cell based alternative products, as a treatment for ailments, such as joint pain, tendon and ligament injuries, neurodegenerative, and autoimmune diseases. The company is also engages in the repackaging and distribution of active pharmaceutical ingredients and other pharmaceutical compounding supplies; and develops and markets nutraceutical products under the Dr. Dave's Best and Nesvik Organics brands, as well as other non-proprietary products in the United States and internationally. The company sells products through e-commerce platforms. BioStem Technologies, Inc. was incorporated in 2006 and is based in Pompano Beach, Florida.
How the Company Makes MoneyBioStem Technologies generates revenue through multiple key streams. Primarily, the company earns income from the processing and storage fees associated with stem cell collection services, where parents pay to store umbilical cord blood and tissue for potential future medical use. Additionally, BSEM monetizes its proprietary stem cell therapies and related products sold to healthcare providers and research institutions. Strategic partnerships with hospitals, clinics, and research organizations further enhance revenue opportunities through collaborative research and development projects. The company may also engage in licensing agreements for its technologies, providing another avenue for income generation.

BioStem Technologies Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Apr 06, 2026
Earnings Call Sentiment Neutral
BioStem Technologies demonstrated resilience and strategic growth through increased product volume, consistent positive adjusted EBITDA, and strong gross margins. The company successfully expanded into new markets despite facing revenue and cash balance declines due to competitive pricing pressures and strategic investments.
Q3-2025 Updates
Positive Updates
Increased Product Volume
Despite a challenging pricing environment, BioStem sold 40% more products on a volume basis compared to the previous quarter, indicating strong underlying demand and market share growth.
Seventh Consecutive Quarter of Positive Adjusted EBITDA
BioStem achieved its seventh consecutive quarter of positive adjusted EBITDA, highlighting the resilience and strength of its business model.
Strong Gross Margins
BioStem maintained industry-leading gross margins, with a gross profit of $9.3 million, representing a gross margin of 88.5% for Q3.
Successful FDA Inspection
BioStem's facility passed a follow-up and routine FDA inspection with no nonconformance observations, indicating a strong quality system and readiness to scale production.
Expansion into New Markets
BioStem expanded into the Medicaid market with initial success in Medi-Cal and Texas Medicaid, and partnered with a Service-Disabled Veteran-Owned Small Business to serve the VA.
Negative Updates
Decreased Revenue
Revenue for the quarter totaled $10.5 million, down from $11 million in the previous quarter and $18.4 million in Q3 of 2024, primarily due to competition from higher-priced products and a lower selling price to Venture.
Cash Balance Decline
BioStem's cash balance decreased from $30.8 million at the end of Q2 to $27.2 million at the end of Q3, largely due to the purchase of land for future headquarters and the timing of collections from Venture Medical.
Company Guidance
During the BioStem Technologies Third Quarter 2025 Earnings Call, CEO Jason Matuszewski and CFO Brandon Poe highlighted several key metrics and strategic initiatives. The company reported Q3 revenue of $10.5 million, down from $11 million in Q2 2025 and $18.4 million in Q3 2024, despite a 40% increase in product volume, attributed to price adjustments under the ASP Plus 6 reimbursement model. Gross profit was $9.3 million, with a gross margin of 88.5%, compared to 93.8% in the prior quarter. Operating expenses were reduced to $7.8 million from $10.2 million in Q2 2025. The company maintained a cash balance of $27.2 million at the end of Q3, supporting its strategic initiatives, including a future uplisting to NASDAQ and expansion into new markets such as Medicaid and the Department of Veteran Affairs. BioStem also reported seven consecutive quarters of positive adjusted EBITDA, underscoring its financial resilience and operational efficiency.

BioStem Technologies Financial Statement Overview

Summary
Strong profitability and cash generation support the score (gross margins consistently above 90%, net margin 10.98%, positive operating and free cash flow with a high FCF-to-net income ratio of 0.98). Offsetting this, TTM revenue growth declined 7.58%, free cash flow growth declined 3.84%, and EBIT/EBITDA margin pressure plus lower ROE (down to 65.93%) signal weakening momentum in fundamentals.
Income Statement
75
Positive
BioStem Technologies shows strong gross profit margins consistently above 90%, indicating efficient cost management. However, recent revenue growth has declined by 7.58% in the TTM, which is a concern. The net profit margin remains healthy at 10.98%, reflecting profitability, but the decline in EBIT and EBITDA margins suggests potential operational challenges.
Balance Sheet
65
Positive
The company's debt-to-equity ratio is low at 0.11, indicating prudent leverage management. However, the return on equity has decreased from 78% to 65.93% in the TTM, suggesting reduced efficiency in generating returns from equity. The equity ratio is not provided, but the overall stability appears moderate.
Cash Flow
70
Positive
Operating cash flow and free cash flow are positive, with a high free cash flow to net income ratio of 0.98, indicating strong cash generation relative to profits. However, the free cash flow growth rate has declined by 3.84% in the TTM, which could impact future liquidity.
BreakdownTTMMar 2025Mar 2024Mar 2023Mar 2022Mar 2021
Income Statement
Total Revenue235.17M301.83M16.69M6.88M4.34M2.52M
Gross Profit228.78M287.86M15.42M5.99M2.87M1.25M
EBITDA15.57M31.49M-7.55M-6.52M-602.00K-2.25M
Net Income20.20M31.88M-8.48M-7.07M-1.45M-2.39M
Balance Sheet
Total Assets62.39M140.55M14.56M3.47M2.67M2.67M
Cash, Cash Equivalents and Short-Term Investments27.16M22.83M239.41K772.14K340.33K100.70K
Total Debt3.39M4.50M4.77M5.21M4.83M5.63M
Total Liabilities12.38M99.67M15.90M7.42M8.47M8.30M
Stockholders Equity50.02M40.88M-1.34M-4.08M-5.96M-5.80M
Cash Flow
Free Cash Flow12.23M24.05M-3.60M-2.11M-152.29K-585.25K
Operating Cash Flow15.27M24.48M-3.50M-1.64M-109.44K-581.57K
Investing Cash Flow-1.80M-1.68M-210.33K-469.48K-7.85K-3.69K
Financing Cash Flow-931.94K-206.78K3.18M597.71K357.42K541.52K

BioStem Technologies Technical Analysis

Technical Analysis Sentiment
Positive
Last Price4.83
Price Trends
50DMA
5.13
Positive
100DMA
4.80
Positive
200DMA
7.57
Negative
Market Momentum
MACD
0.21
Positive
RSI
51.93
Neutral
STOCH
52.36
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BSEM, the sentiment is Positive. The current price of 4.83 is below the 20-day moving average (MA) of 6.38, below the 50-day MA of 5.13, and below the 200-day MA of 7.57, indicating a neutral trend. The MACD of 0.21 indicates Positive momentum. The RSI at 51.93 is Neutral, neither overbought nor oversold. The STOCH value of 52.36 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for BSEM.

BioStem Technologies Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
68
Neutral
$102.61M7.3155.46%11.78%37.44%
59
Neutral
$128.76M6.3419.23%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$448.91M-11.85-64.12%-29.73%
49
Neutral
$160.01M-2.83-271.32%-75.77%-31.24%
46
Neutral
$267.85M-0.53-51.70%-100.00%-0.58%
46
Neutral
$185.70M-1.58-46.09%-80.88%-388.61%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BSEM
BioStem Technologies
6.05
-7.15
-54.15%
CBIO
Crescent Biopharma
11.65
-16.41
-58.48%
VYGR
Voyager Therapeutics
3.49
-0.61
-14.88%
DMAC
Diamedica Therapeutics
8.42
2.17
34.72%
BDTX
Black Diamond Therapeutics
2.33
0.16
7.37%
IPHA
Innate Pharma
1.62
-0.91
-35.97%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 04, 2026