BioStem Technologies (BSEM)
:BSEM
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BioStem Technologies (BSEM) AI Stock Analysis

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BSEM

BioStem Technologies

(OTC:BSEM)

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Outperform 70 (OpenAI - 4o)
Rating:70Outperform
Price Target:
$3.50
▼(-33.96% Downside)
BioStem Technologies' overall stock score reflects strong financial performance and valuation, bolstered by strategic growth initiatives and consistent profitability. However, technical indicators suggest bearish momentum, which tempers the overall score. The company's low P/E ratio and strategic market expansions are significant positives, while recent revenue declines and technical weaknesses present challenges.

BioStem Technologies (BSEM) vs. SPDR S&P 500 ETF (SPY)

BioStem Technologies Business Overview & Revenue Model

Company DescriptionBioStem Technologies (BSEM) is a biotechnology company focused on advancing regenerative medicine and cellular therapy. The company specializes in developing innovative solutions for tissue repair and regeneration, leveraging its proprietary processes for the extraction and application of stem cells derived from various biological sources. BSEM operates primarily in the healthcare sector, offering a range of products and services that cater to both clinical and research applications, including stem cell storage, processing, and therapeutic treatments.
How the Company Makes MoneyBioStem Technologies generates revenue through multiple key streams. Primarily, the company earns income from the processing and storage fees associated with stem cell collection services, where parents pay to store umbilical cord blood and tissue for potential future medical use. Additionally, BSEM monetizes its proprietary stem cell therapies and related products sold to healthcare providers and research institutions. Strategic partnerships with hospitals, clinics, and research organizations further enhance revenue opportunities through collaborative research and development projects. The company may also engage in licensing agreements for its technologies, providing another avenue for income generation.

BioStem Technologies Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Apr 06, 2026
Earnings Call Sentiment Neutral
BioStem Technologies demonstrated resilience and strategic growth through increased product volume, consistent positive adjusted EBITDA, and strong gross margins. The company successfully expanded into new markets despite facing revenue and cash balance declines due to competitive pricing pressures and strategic investments.
Q3-2025 Updates
Positive Updates
Increased Product Volume
Despite a challenging pricing environment, BioStem sold 40% more products on a volume basis compared to the previous quarter, indicating strong underlying demand and market share growth.
Seventh Consecutive Quarter of Positive Adjusted EBITDA
BioStem achieved its seventh consecutive quarter of positive adjusted EBITDA, highlighting the resilience and strength of its business model.
Strong Gross Margins
BioStem maintained industry-leading gross margins, with a gross profit of $9.3 million, representing a gross margin of 88.5% for Q3.
Successful FDA Inspection
BioStem's facility passed a follow-up and routine FDA inspection with no nonconformance observations, indicating a strong quality system and readiness to scale production.
Expansion into New Markets
BioStem expanded into the Medicaid market with initial success in Medi-Cal and Texas Medicaid, and partnered with a Service-Disabled Veteran-Owned Small Business to serve the VA.
Negative Updates
Decreased Revenue
Revenue for the quarter totaled $10.5 million, down from $11 million in the previous quarter and $18.4 million in Q3 of 2024, primarily due to competition from higher-priced products and a lower selling price to Venture.
Cash Balance Decline
BioStem's cash balance decreased from $30.8 million at the end of Q2 to $27.2 million at the end of Q3, largely due to the purchase of land for future headquarters and the timing of collections from Venture Medical.
Company Guidance
During the BioStem Technologies Third Quarter 2025 Earnings Call, CEO Jason Matuszewski and CFO Brandon Poe highlighted several key metrics and strategic initiatives. The company reported Q3 revenue of $10.5 million, down from $11 million in Q2 2025 and $18.4 million in Q3 2024, despite a 40% increase in product volume, attributed to price adjustments under the ASP Plus 6 reimbursement model. Gross profit was $9.3 million, with a gross margin of 88.5%, compared to 93.8% in the prior quarter. Operating expenses were reduced to $7.8 million from $10.2 million in Q2 2025. The company maintained a cash balance of $27.2 million at the end of Q3, supporting its strategic initiatives, including a future uplisting to NASDAQ and expansion into new markets such as Medicaid and the Department of Veteran Affairs. BioStem also reported seven consecutive quarters of positive adjusted EBITDA, underscoring its financial resilience and operational efficiency.

BioStem Technologies Financial Statement Overview

Summary
BioStem Technologies demonstrates strong profitability and cash generation capabilities, with robust gross and net profit margins. However, recent declines in revenue growth and free cash flow growth pose potential risks. The company's low leverage is a positive factor, but the decrease in return on equity suggests a need for improved efficiency in utilizing equity capital.
Income Statement
75
Positive
BioStem Technologies shows strong gross profit margins consistently above 90%, indicating efficient cost management. However, recent revenue growth has declined by 7.58% in the TTM, which is a concern. The net profit margin remains healthy at 10.98%, reflecting profitability, but the decline in EBIT and EBITDA margins suggests potential operational challenges.
Balance Sheet
65
Positive
The company's debt-to-equity ratio is low at 0.11, indicating prudent leverage management. However, the return on equity has decreased from 78% to 65.93% in the TTM, suggesting reduced efficiency in generating returns from equity. The equity ratio is not provided, but the overall stability appears moderate.
Cash Flow
70
Positive
Operating cash flow and free cash flow are positive, with a high free cash flow to net income ratio of 0.98, indicating strong cash generation relative to profits. However, the free cash flow growth rate has declined by 3.84% in the TTM, which could impact future liquidity.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue307.26M301.83M16.69M6.88M4.34M2.52M
Gross Profit297.89M287.86M15.42M5.99M2.87M1.25M
EBITDA23.39M31.49M-7.55M-6.52M-602.00K-2.25M
Net Income26.26M31.88M-8.48M-7.07M-1.45M-2.39M
Balance Sheet
Total Assets112.61M140.55M14.56M3.47M2.67M2.67M
Cash, Cash Equivalents and Short-Term Investments30.84M22.83M239.41K772.14K340.33K100.70K
Total Debt3.59M4.50M4.77M5.21M4.83M5.63M
Total Liabilities64.52M99.67M15.90M7.42M8.47M8.30M
Stockholders Equity48.09M40.88M-1.34M-4.08M-5.96M-5.80M
Cash Flow
Free Cash Flow26.36M24.05M-3.60M-2.11M-152.29K-585.25K
Operating Cash Flow27.11M24.48M-3.50M-1.64M-109.44K-581.57K
Investing Cash Flow-2.00M-1.68M-210.33K-469.48K-7.85K-3.69K
Financing Cash Flow-840.43K-206.78K3.18M597.71K357.42K541.52K

BioStem Technologies Technical Analysis

Technical Analysis Sentiment
Negative
Last Price5.30
Price Trends
50DMA
4.71
Negative
100DMA
7.19
Negative
200DMA
9.89
Negative
Market Momentum
MACD
-0.34
Positive
RSI
33.14
Neutral
STOCH
22.41
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BSEM, the sentiment is Negative. The current price of 5.3 is above the 20-day moving average (MA) of 4.33, above the 50-day MA of 4.71, and below the 200-day MA of 9.89, indicating a bearish trend. The MACD of -0.34 indicates Positive momentum. The RSI at 33.14 is Neutral, neither overbought nor oversold. The STOCH value of 22.41 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for BSEM.

BioStem Technologies Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
70
Outperform
$64.95M3.9555.46%11.78%37.44%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$167.09M-271.32%-75.77%-31.24%
46
Neutral
$218.51M-46.09%-80.88%-388.61%
42
Neutral
$308.82M-64.12%-29.73%
33
Underperform
$228.47M11.0519.23%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BSEM
BioStem Technologies
3.33
-9.37
-73.78%
CBIO
Crescent Biopharma
13.00
-24.91
-65.71%
VYGR
Voyager Therapeutics
4.28
-0.99
-18.79%
DMAC
Diamedica Therapeutics
6.90
2.86
70.79%
BDTX
Black Diamond Therapeutics
3.97
1.42
55.69%
IPHA
Innate Pharma
1.80
0.31
20.81%

BioStem Technologies Corporate Events

BioStem Technologies Q3 Earnings Call Highlights Resilience
Nov 15, 2025

BioStem Technologies recently held its third-quarter earnings call, showcasing a strategic growth trajectory despite facing some financial challenges. The overall sentiment was one of resilience and optimism, as the company highlighted its ability to increase product volume and maintain strong gross margins, even as it navigated competitive pricing pressures and strategic investments that impacted revenue and cash balances.

BioStem Technologies Reports Q3 2025 Financial Results
Nov 14, 2025

BioStem Technologies, Inc. is a MedTech company specializing in the development, manufacturing, and commercialization of placental-derived products for advanced wound care, leveraging its proprietary BioREtain® processing method. The company operates within the regenerative medicine sector and is recognized for its innovative approach to harnessing the natural properties of perinatal tissue.

BioStem Technologies’ Promising Clinical Trial for Venous Leg Ulcers: A Potential Game-Changer
Oct 27, 2025

BioStem Technologies is conducting a clinical study titled A Prospective, Multicenter, Randomized, Controlled Trial of Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC. The study aims to determine if the application of BioREtain® Amnion Chorion (BR-AC) can enhance healing in patients with non-healing venous leg ulcers compared to standard care alone. This research is significant as it could offer a new treatment avenue for a condition that affects many patients worldwide.

BioStem Technologies’ Promising Study on Diabetic Foot Ulcers: A Potential Game-Changer
Oct 27, 2025

BioStem Technologies is conducting a clinical study titled A Prospective, Multicenter, Randomized, Controlled Trial of Non-healing Diabetic Foot Ulcers Treated With Standard Care With or Without BR-AM. The study aims to evaluate the safety and efficacy of the BioREtain® Amniotic Membrane (BR-AM) in conjunction with standard care compared to standard care alone for treating diabetic foot ulcers. This research is significant as it could offer a new treatment option for a challenging condition.

BioStem Technologies’ Earnings Call: Mixed Sentiment Amid Growth Plans
Sep 1, 2025

BioStem Technologies’ recent earnings call presented a mixed sentiment, reflecting both optimism and challenges. While the company continues to demonstrate operational and clinical advancements with a positive EBITDA and strategic growth initiatives, it faces significant hurdles due to a notable revenue decline and uncertainties in reimbursement. The sentiment remains balanced, with strong financial metrics and future potential weighed against current market and competitive pressures.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 18, 2025