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TuHURA Biosciences (HURA)
NASDAQ:HURA

TuHURA Biosciences (HURA) AI Stock Analysis

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HURA

TuHURA Biosciences

(NASDAQ:HURA)

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Neutral 41 (OpenAI - 5.2)
Rating:41Neutral
Price Target:
$0.54
▲(16.52% Upside)
The score is held down primarily by weak financial performance (pre-revenue with ongoing losses and increasing cash burn) and very bearish technicals (price below all key moving averages with negative MACD). Valuation is also limited by a negative P/E and no dividend, while corporate events are mixed—financing and pipeline progress are offset by heightened Nasdaq listing compliance risk.
Positive Factors
Pipeline expansion via acquisition
Acquiring Kineta and rights to TBS-2025 materially expands TuHURA’s clinical-stage portfolio, diversifying beyond a single lead asset. This strengthens long-term R&D optionality, enables new combination strategies, and increases partnership or licensing opportunities, improving strategic resilience.
Late-stage development of lead asset
Advancing IFx-2.0 into Phase 3 as an adjunct to a major PD-1 inhibitor represents a step toward regulatory clarity and potential accelerated approval. Later-stage progress reduces technical risk versus early trials and shortens time to potential commercial viability if endpoints are met.
Low leverage and asset-backed financing
Very low reported debt provides financial flexibility for a pre-revenue biotech. The ability to secure a bridge loan using patents as collateral demonstrates tangible IP value and supports non-dilutive or asset-backed financing options to fund clinical milestones.
Negative Factors
Rising cash burn
Sustained negative operating and free cash flows with material growth in burn over recent years heighten funding vulnerability. Persistent cash consumption requires repeated capital access and can compress runway, forcing prioritization or delay of programs if financing is constrained.
Pre-revenue and widening losses
The company remains pre-revenue with volatile, substantial net losses driven by R&D spend. Without commercialization or milestone receipts, margins and profitability remain theoretical; long-term value hinges on successful trials which are uncertain and time-consuming.
Dependence on dilutive financing
Frequent use of ATM, shelf registrations, bridge loans and registered offerings signals ongoing reliance on capital markets. This creates dilution risk and ties program funding to market access, potentially reducing shareholder value and constraining strategic choices over the medium term.

TuHURA Biosciences (HURA) vs. SPDR S&P 500 ETF (SPY)

TuHURA Biosciences Business Overview & Revenue Model

Company DescriptionTuHURA Biosciences, Inc. is a phase 3 registration-stage immuno-oncology company developing novel technologies to overcome resistance to cancer immunotherapy. The company is headquartered in Tampa, FL.
How the Company Makes MoneyTuHURA Biosciences generates revenue through multiple streams, primarily from the sale of its diagnostic tests and personalized therapeutic products. The company collaborates with healthcare providers, research institutions, and pharmaceutical companies to integrate its solutions into clinical settings, driving adoption and sales. Additionally, TuHURA may enter into licensing agreements and strategic partnerships to commercialize its technologies, expanding its market reach and generating royalties. Grants and funding from research initiatives may also contribute to the company's earnings, supporting its ongoing research and development efforts.

TuHURA Biosciences Financial Statement Overview

Summary
Very weak fundamentals typical of an early-stage biotech: no revenue, persistent losses, and rising cash burn (2024 operating cash flow -14.7M; free cash flow -14.8M). The balance sheet is a relative positive with low debt versus equity in 2024, but equity volatility and ongoing negative returns reflect continued dependence on external funding.
Income Statement
12
Very Negative
The company remains pre-revenue (revenue is 0 across the provided annual periods), so losses are driven by operating spend rather than weak demand. Net loss widened in 2024 (net income -21.7M vs. -29.3M in 2023 and -9.4M in 2022), showing meaningful volatility and an elevated burn profile. While 2024 losses improved versus 2023, the overall trajectory still reflects a business that has not yet converted R&D investment into commercial revenue, keeping profitability and margin quality weak.
Balance Sheet
55
Neutral
Leverage is currently low in 2024, with total debt at 0.20M against stockholders’ equity of 14.6M (very modest debt relative to equity), which is a positive for financial flexibility. However, equity has been volatile (negative in 2021 and 2023, then positive in 2022 and 2024), indicating meaningful financing or valuation swings and a less stable capital structure over time. Returns on equity are negative in years with positive equity (e.g., 2024), consistent with ongoing losses.
Cash Flow
18
Very Negative
Cash generation remains weak, with operating cash flow and free cash flow negative each year provided (2024 operating cash flow -14.7M; free cash flow -14.8M), reflecting continued cash burn. Cash burn increased from 2022 to 2024 (operating cash flow -7.5M in 2022 to -14.7M in 2024), which raises funding risk if capital markets tighten. A positive note is that free cash flow broadly tracks net income (free cash flow to net income ~1.0), suggesting losses are largely cash-based rather than driven by large non-cash accounting items.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-17.64K-116.71K0.000.000.00-32.00K
EBITDA-17.16M-17.43M-29.12M-9.56M-6.01M-38.15M
Net Income-15.52M-21.68M-29.32M-9.37M-7.02M-38.30M
Balance Sheet
Total Assets34.62M19.97M4.36M15.20M6.40M13.54M
Cash, Cash Equivalents and Short-Term Investments8.51M12.66M3.67M14.25M5.55M10.54M
Total Debt558.97K202.54K2.34M138.22K644.07K0.00
Total Liabilities15.17M5.37M5.92M2.89M7.15M2.96M
Stockholders Equity19.45M14.59M-1.56M12.30M-747.82K10.58M
Cash Flow
Free Cash Flow-15.54M-14.79M-12.03M-7.54M-6.57M-18.87M
Operating Cash Flow-15.48M-14.73M-11.95M-7.51M-6.56M-18.86M
Investing Cash Flow-2.13M-6.05M-1.30M-36.28K-3.28K964.00K
Financing Cash Flow4.63M29.77M2.66M16.25M7.04M26.04M

TuHURA Biosciences Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.46
Price Trends
50DMA
1.01
Negative
100DMA
1.70
Negative
200DMA
2.33
Negative
Market Momentum
MACD
-0.14
Negative
RSI
16.90
Positive
STOCH
13.45
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HURA, the sentiment is Negative. The current price of 0.46 is below the 20-day moving average (MA) of 0.66, below the 50-day MA of 1.01, and below the 200-day MA of 2.33, indicating a bearish trend. The MACD of -0.14 indicates Negative momentum. The RSI at 16.90 is Positive, neither overbought nor oversold. The STOCH value of 13.45 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HURA.

TuHURA Biosciences Risk Analysis

TuHURA Biosciences disclosed 72 risk factors in its most recent earnings report. TuHURA Biosciences reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

TuHURA Biosciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$77.07M-0.46-209.00%40.22%
49
Neutral
$27.89M-0.67-94.31%-53.18%
47
Neutral
$114.73M-0.65-328.45%-10.36%42.36%
47
Neutral
$90.92M-2.17-109.73%50.39%
45
Neutral
$98.28M-1.36-33.41%81.19%
41
Neutral
$28.16M-0.71-418.06%99.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HURA
TuHURA Biosciences
0.46
-4.02
-89.67%
AGEN
Agenus
2.89
-1.01
-25.90%
INO
Inovio Pharmaceuticals
1.67
-0.37
-18.14%
SKYE
Skye Bioscience
0.87
-2.04
-70.10%
BMEA
Biomea Fusion
1.09
-3.07
-73.80%
CGTX
Cognition Therapeutics
1.03
0.38
58.46%

TuHURA Biosciences Corporate Events

Delistings and Listing ChangesRegulatory Filings and Compliance
TuHURA Biosciences Receives Nasdaq Minimum Bid Price Notice
Negative
Jan 30, 2026

On January 29, 2026, TuHURA Biosciences disclosed that it had received a notice from Nasdaq stating that its common stock had closed below $1.00 per share for 35 consecutive business days as of January 28, 2026, placing the company out of compliance with the exchange’s minimum bid price rule for continued listing. The company has been granted an initial 180-calendar day grace period, until July 28, 2026, to restore compliance by maintaining a closing bid price of at least $1.00 for a minimum of ten consecutive business days, with the possibility of an additional 180-day extension if certain other listing criteria are met and, if needed, a reverse stock split is pursued. While the notice does not immediately affect trading or SEC reporting requirements, continued non-compliance could ultimately lead to delisting proceedings, adding pressure on management to stabilize the share price and preserve the company’s Nasdaq listing status.

The most recent analyst rating on (HURA) stock is a Hold with a $0.54 price target. To see the full list of analyst forecasts on TuHURA Biosciences stock, see the HURA Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
TuHURA Biosciences Announces Securities Purchase Agreement
Positive
Dec 10, 2025

On December 9, 2025, TuHURA Biosciences announced a securities purchase agreement with investors for a registered direct offering of 9,462,423 shares of common stock and accompanying warrants, expected to raise approximately $15.6 million in three tranches. The proceeds will be used for working capital, satisfying a $3.4 million bridge note obligation, and general corporate purposes, impacting the company’s financial operations and potentially strengthening its market position.

The most recent analyst rating on (HURA) stock is a Buy with a $8.00 price target. To see the full list of analyst forecasts on TuHURA Biosciences stock, see the HURA Stock Forecast page.

Private Placements and Financing
TuHURA Biosciences Amends Loan Agreement, Secures Full $3M
Neutral
Dec 5, 2025

TuHURA Biosciences, Inc. entered into a Secured Promissory Note and Loan Agreement with the Matthew Nachtrab Revocable Trust, initially securing a loan of $1.5 million with a total potential of $3.0 million. On December 2, 2025, the agreement was amended to extend the loan availability period and adjust the warrants issuable to the lender. Following this amendment, TuHURA borrowed an additional $1.5 million, reaching the full $3.0 million loan capacity, and issued warrants for 234,783 shares of common stock.

The most recent analyst rating on (HURA) stock is a Buy with a $8.00 price target. To see the full list of analyst forecasts on TuHURA Biosciences stock, see the HURA Stock Forecast page.

Regulatory Filings and Compliance
TuHURA Biosciences’ Shelf Registration Statement Effective
Neutral
Nov 25, 2025

On November 22, 2025, TuHURA Biosciences, Inc.’s Shelf Registration Statement became effective, allowing the company to continue offering shares previously registered under a Resale Registration Statement. This development enables the selling securityholders to offer shares from time to time under the new registration, potentially impacting the company’s market operations and investor relations.

The most recent analyst rating on (HURA) stock is a Buy with a $8.00 price target. To see the full list of analyst forecasts on TuHURA Biosciences stock, see the HURA Stock Forecast page.

Business Operations and StrategyM&A Transactions
TuHURA Biosciences Completes Acquisition of Kineta, Inc.
Positive
Nov 18, 2025

On June 30, 2025, TuHURA Biosciences completed its acquisition of Kineta, Inc., following a series of mergers that began with an agreement on December 11, 2024. This acquisition included the rights to Kineta’s novel antibody, TBS-2025, and was executed through a combination of cash and stock. The mergers were accounted for as a business combination under U.S. GAAP, and TuHURA has provided pro forma financial statements to reflect these transactions as if they had occurred on January 1, 2024. This strategic move is expected to enhance TuHURA’s market position and operational capabilities.

The most recent analyst rating on (HURA) stock is a Buy with a $8.00 price target. To see the full list of analyst forecasts on TuHURA Biosciences stock, see the HURA Stock Forecast page.

Private Placements and Financing
TuHURA Biosciences Announces $50M Stock Offering Agreement
Neutral
Nov 4, 2025

On November 3, 2025, TuHURA Biosciences entered into an At The Market Offering Agreement with H.C. Wainwright & Co., LLC to potentially sell up to $50 million in common stock. The proceeds from this offering are intended for working capital and general corporate purposes, although there is no obligation to sell shares, and the agreement can be suspended or terminated by either party.

The most recent analyst rating on (HURA) stock is a Buy with a $12.00 price target. To see the full list of analyst forecasts on TuHURA Biosciences stock, see the HURA Stock Forecast page.

M&A TransactionsProduct-Related Announcements
TuHURA Biosciences Plans Phase 2 Trial for TBS-2025
Positive
Nov 3, 2025

In June 2025, TuHURA Biosciences initiated a Phase 3 trial for its lead product, IFx-2.0, as an adjunctive therapy to Keytruda in treating advanced Merkel cell carcinoma, aiming for accelerated FDA approval. Following its acquisition of Kineta, TuHURA plans a Phase 2 trial for TBS-2025, a VISTA-inhibiting antibody, in combination with a menin inhibitor for treating acute myeloid leukemia, potentially enhancing response rates and reducing relapse.

The most recent analyst rating on (HURA) stock is a Buy with a $12.00 price target. To see the full list of analyst forecasts on TuHURA Biosciences stock, see the HURA Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
TuHURA Biosciences Secures $3M Bridge Loan Agreement
Positive
Oct 31, 2025

On October 27, 2025, TuHURA Biosciences entered into a Secured Promissory Note and Loan Agreement with the Matthew Nachtrab Revocable Trust for a bridge loan of up to $3,000,000 to be used for working capital. The loan is secured by U.S. patents related to TuHURA’s ImmuneFxTM technology and includes the issuance of warrants to purchase common stock, reflecting a strategic move to bolster financial resources and potentially enhance its market position.

The most recent analyst rating on (HURA) stock is a Buy with a $12.00 price target. To see the full list of analyst forecasts on TuHURA Biosciences stock, see the HURA Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 31, 2026