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Bio-Rad Laboratories (BIO)
NYSE:BIO

Bio-Rad Laboratories (BIO) AI Stock Analysis

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BIO

Bio-Rad Laboratories

(NYSE:BIO)

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Neutral 64 (OpenAI - 5.2)
Rating:64Neutral
Price Target:
$291.00
▲(7.26% Upside)
Action:ReiteratedDate:02/21/26
The score is anchored by solid fundamentals—conservative leverage and consistently positive free cash flow—tempered by volatile reported earnings. Technicals are a meaningful headwind with clear downside momentum. Valuation is a support (low P/E), while the latest call adds moderate confidence via steady 2026 margin/FCF outlook but highlights near-term execution and segment headwinds.
Positive Factors
Balance sheet strength
Conservative leverage and a sizable equity cushion provide long-term financial flexibility to fund R&D, absorb cyclical downturns, and support strategic moves (buybacks/M&A). A strong balance sheet reduces refinancing risk and underpins durable operational resilience over multiple cycles.
Consistent cash generation
Reliable operating and free cash flow enables sustained investment in product development, commercialization, and capital returns. Healthy FCF supports buybacks and M&A while insulating the company from temporary revenue volatility and funding constraints in research-driven end markets.
Product momentum & M&A
Momentum in ddPCR and an accelerating QX700 funnel, combined with earlier-than-expected accretion from the Stilla deal, signal structural product/portfolio strengthening. These durable product wins and targeted M&A expand addressable markets and support sustainable revenue mix improvement.
Negative Factors
Earnings volatility
Large swings in GAAP profitability reduce confidence in recurring earnings power and complicate forecasting. Volatile reported results, partly from valuation changes and impairments, suggest profit variability that can persist across reporting periods and hinder reliable margin planning.
Process chromatography concentration risk
A concentrated, lumpy process chromatography business creates durable revenue volatility and execution risk. Regulatory/customer production shifts can cause multi-quarter declines; given its material size, weak chromatography demand can offset growth in core Life Science despite other product gains.
Margin pressure & impairments
Significant impairment charges and recurring supply-chain/expedite costs signal structural execution gaps. Persistent cost pressures and write-offs can depress sustainable gross and operating margins, limit reinvestment capacity, and suggest management must address deeper operational inefficiencies.

Bio-Rad Laboratories (BIO) vs. SPDR S&P 500 ETF (SPY)

Bio-Rad Laboratories Business Overview & Revenue Model

Company DescriptionBio-Rad Laboratories, Inc. manufactures, and distributes life science research and clinical diagnostic products in the United States, Europe, Asia, Canada, and Latin America. The company operates through Life Science and Clinical Diagnostics segments. The Life Science segment develops, manufactures, and markets a range of reagents, apparatus, and laboratory instruments that are used in research techniques, biopharmaceutical production processes, and food testing regimes. It focuses on selected segments of the life sciences market in proteomics, genomics, biopharmaceutical production, cellular biology, and food safety. This segment serves universities and medical schools, industrial research organizations, government agencies, pharmaceutical manufacturers, biotechnology researchers, food producers, and food testing laboratories. The Clinical Diagnostics segment designs, manufactures, sells, and supports test systems, informatics systems, test kits, and specialized quality controls for clinical laboratories in the diagnostics market. This segment offers reagents, instruments, and software, which address specific niches within the in vitro diagnostics test market. It sells its products to reference laboratories, hospital laboratories, state newborn screening facilities, physicians' office laboratories, and transfusion laboratories. In addition, the company offers products and systems to separate complex chemical and biological materials, as well as to identify, analyze, and purify components. The company offers its products through its direct sales force, as well as through distributors, agents, brokers, and resellers. Bio-Rad Laboratories, Inc. was founded in 1952 and is headquartered in Hercules, California.
How the Company Makes MoneyBio-Rad makes money primarily through the sale of its products and services in the life science and clinical diagnostics markets. The company generates revenue through multiple streams, including the sale of laboratory instruments, reagents, consumables, and software solutions. Key revenue streams include instrument sales, which provide significant margins, and recurring revenues from consumables and reagent sales. Additionally, Bio-Rad has established significant partnerships and collaborations with academic institutions, biotech firms, and healthcare providers, enhancing its market presence and driving sales. The company also invests in research and development to innovate and expand its product offerings, which contributes to its long-term revenue growth.

Bio-Rad Laboratories Key Performance Indicators (KPIs)

Any
Any
Revenue by Geography
Revenue by Geography
Breaks down revenue across different regions, revealing where the company is strongest and where it may face risk or growth potential due to local economic conditions or market share shifts.
Chart InsightsBio-Rad's revenue in the United States shows a declining trend, while EMEA and APAC regions exhibit fluctuations with no clear growth pattern. The latest earnings call highlights strong performance in process chromatography and Droplet Digital PCR, which could drive future growth. However, challenges such as gross margin declines and market softness, particularly in China and academic sectors, may impact regional revenue stability. The company's strategic acquisitions and product advancements are expected to mitigate some of these risks, with a cautious outlook for revenue growth in 2025.
Data provided by:The Fly

Bio-Rad Laboratories Earnings Call Summary

Earnings Call Date:Feb 12, 2026
(Q4-2025)
|
% Change Since: |
Next Earnings Date:Apr 30, 2026
Earnings Call Sentiment Neutral
The call presented a mix of encouraging progress in strategic growth areas (diagnostics rebound, ddPCR/QX700 momentum, earlier-than-expected accretion from the Stilla acquisition, robust free cash flow and a strong balance sheet) alongside material execution and margin challenges (Q4 gross margin pressure, one-time write-offs, GAAP impairment charges, Life Science softness and near-term process chromatography headwinds). Management provided conservative but constructive 2026 guidance and detailed operational actions to address supply chain and cost issues. Overall, positives around cash generation, product momentum and disciplined M&A/capital allocation are balanced by near-term profitability and execution risks.
Q4-2025 Updates
Positive Updates
Revenue Growth in Q4 and Full Year Stability
Q4 2025 net sales were $693 million, up 3.9% reported and 1.7% currency-neutral versus Q4 2024. Full year 2025 net sales were $2.583 billion, up 0.7% reported and essentially flat on a currency-neutral basis versus 2024.
Clinical Diagnostics Returned to Growth
Q4 Clinical Diagnostics sales were ~$425 million, an 8.4% increase reported and 5.6% currency-neutral versus Q4 2024, driven by quality control and blood typing products; full year Diagnostics sales grew 1.6% reported (0.8% currency-neutral).
ddPCR Momentum and Successful QX700 Launch
ddPCR portfolio posted mid-single-digit year-over-year growth in Q4; QX700 instrument sales meaningfully accelerated in Q4 and helped expand the order funnel entering 2026. Management expects ddPCR to be a core long-term growth pillar and guides ddPCR growth at mid-single digits for 2026.
Stilla Acquisition Accreting Sooner Than Expected
Management indicated the Stilla acquisition will be accretive by mid-2026 — 6 to 12 months earlier than initially expected — and Stilla contributed mid-single-digit millions of revenue in Q4.
Strong Cash Generation and Free Cash Flow Improvement
Q4 2025 net cash from operations was $165 million (vs. $124M prior year); full year operating cash flow improved to $532 million (vs. $455M). Free cash flow for 2025 was ~$375 million (vs. $290M), with a free cash flow to non-GAAP net income conversion of 138%.
Balance Sheet and Capital Allocation
Total cash and short-term investments of $1.541 billion at year-end; repurchased 1.2 million shares in 2025 for ~$296 million and 1.9 million shares total since Q1 2024 (~$494M), reducing share count by ~6.6%. Company has ~$285 million remaining under current buyback authorization.
Process Chromatography Full-Year Strength (Management Commentary)
Management stated the process chromatography business delivered over 20% growth in 2025 (noting this business can be lumpy and concentrated on select commercial therapeutics and vaccines).
Clear and Conservative 2026 Guidance
Company guided to 2026 currency-neutral revenue growth of 0.5%–1.5% (Q1 down low-single digits with sequential improvement), full-year non-GAAP gross margin 54.0%–54.5%, non-GAAP operating margin 12.0%–12.5%, and free cash flow $375M–$395M.
Negative Updates
Gross Margin Pressure and Execution-Related Supply Chain Costs
Q4 2025 GAAP gross margin was 49.8% versus 51.2% in Q4 2024; Q4 non-GAAP gross margin was 52.5% versus 53.9% a year ago. Full year 2025 non-GAAP gross margin declined to 53.3% from 55.0% in 2024. Q4 was pressured by higher-than-anticipated expedited freight, overtime and supply chain costs related to compressed delivery timelines (90 days of work in 30 days due to U.S. government shutdown) and slower procurement savings.
Q4 GAAP Operating Loss and Impairments
Q4 2025 GAAP operating loss was approximately $119 million versus operating income of ~$58 million in Q4 2024. GAAP results included ~$173 million of impairment charges for purchased intangibles and other items stemming from R&D reprioritization and portfolio rationalization.
Non-GAAP Profitability Declines
Q4 non-GAAP operating margin declined to 12.0% from 13.8% in Q4 2024. Q4 non-GAAP net income was $68 million ($2.51/diluted) versus $81 million ($2.90) a year ago. Full year non-GAAP operating margin fell to 12.1% from 12.9% and non-GAAP net income to $271 million ($9.92) from $291 million ($10.31).
Life Science Segment Softness and Process Chromatography Headwinds
Q4 Life Science sales were $268 million, down 2.6% reported and 4.0% currency-neutral versus Q4 2024. Management expects process chromatography to decline ~mid-teens in 2026 due to regulatory changes and customer production efficiencies; they described the product line as subject to quarter-to-quarter lumpiness and concentration risk. Core Life Science excluding process chromatography is expected to grow ~nearly 4% in 2026, implying heavy offset from process chromatography weakness.
Execution and Cost Pressures on SG&A
Q4 SG&A was $221 million (31.9% of sales) vs $204 million (30.6% of sales) in Q4 2024. Non-GAAP SG&A rose to $215M from $200M, primarily due to higher employee-related costs.
Q4 One-Time Charges and Write-Offs
Q4 non-GAAP gross margin excluded $13 million of one-time inventory and other write-offs associated with product portfolio rationalization, on top of restructuring and amortization of purchased intangible charges.
Market Demand Headwinds in Academia and Early-Stage Biotech
Cautious spending in academia and government weighed on instrument demand; biopharma funding improved but remains skewed toward later-stage companies, constraining recovery in core Life Science end markets.
Reported Net Income Affected by Equity Valuation Volatility
Q4 reported net income was $720 million ($26.65/diluted), driven by an $800 million change in fair market value of Sartorius AG shares. Management emphasized non-GAAP measures exclude this equity value change to reflect underlying operations, highlighting volatility in reported (GAAP) results.
Company Guidance
Bio‑Rad guided 2026 to full‑year currency‑neutral revenue growth of 0.5%–1.5% (Q1 down low‑single‑digit y/y with sequential improvement), Life Science +0%–0.5% (core Life Science ex‑process chromatography ≈ +4%, ddPCR mid‑single‑digit), process chromatography down ≈ mid‑teens in 2026 but expected to be mid‑single‑digit long term, and Diagnostics +1%–2% (quality controls mid‑single‑digit; Diagnostics ex‑QC low‑single‑digit). They forecast full‑year non‑GAAP gross margin 54%–54.5% (Q1 gross margin up ~100 bps vs Q4‑2025), non‑GAAP operating margin 12%–12.5% (including ~50 bp headwind from reduced process chromatography sales), a non‑GAAP tax rate ≈23%, free cash flow ~$375M–$395M, ~$285M available for buybacks, and that 2025 restructuring savings are reflected in the outlook.

Bio-Rad Laboratories Financial Statement Overview

Summary
Strong balance sheet (low leverage, sizable equity cushion) and consistently positive operating/free cash flow support business durability. The key drag is earnings quality: reported profitability swung sharply from large losses (2022–2024) to strong profits (2025) while revenue was mostly stable, reducing confidence in repeatable margins.
Income Statement
58
Neutral
Revenue has been broadly stable over the last several years, with low-to-negative growth in 2022–2024 followed by a return to slight growth in 2025. Gross margins remain solid (low-to-mid 50s), indicating resilient product economics. However, profitability has been volatile: 2022–2024 show large reported losses and negative profit margins despite positive operating profit in those years, then 2025 rebounds to a strong positive net margin. This swingy earnings profile reduces confidence in the durability of reported profits even with healthy gross profit.
Balance Sheet
79
Positive
Leverage looks conservative, with debt-to-equity staying low across periods and improving again in 2025 versus 2024. Equity remains sizable relative to total assets, providing a meaningful cushion and flexibility. The main weakness is variability in shareholder returns, with return on equity negative in 2022–2024 and then positive again in 2025—suggesting reported earnings volatility rather than balance-sheet strain.
Cash Flow
72
Positive
Operating cash flow and free cash flow are consistently positive across all years, which supports underlying business quality despite reported net-income volatility. Cash generation improved in 2024–2025 versus 2022–2023, and free cash flow grew strongly in 2025. A watch item is that cash flow relative to accounting earnings has not been consistently strong (e.g., operating cash flow was below net income in 2025), but overall cash conversion remains healthy and free cash flow is meaningfully positive.
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue2.58B2.57B2.67B2.80B2.92B
Gross Profit1.34B1.38B1.43B1.57B1.64B
EBITDA475.90M-2.14B-654.80M-4.49B5.59B
Net Income759.90M-1.84B-637.32M-3.63B4.25B
Balance Sheet
Total Assets10.58B9.36B12.30B13.50B17.80B
Cash, Cash Equivalents and Short-Term Investments1.54B1.66B1.61B1.79B869.92M
Total Debt1.53B1.37B1.41B1.39B223.38M
Total Liabilities3.12B2.79B3.56B3.89B4.11B
Stockholders Equity7.45B6.57B8.74B9.62B13.69B
Cash Flow
Free Cash Flow374.60M266.20M218.26M80.29M535.72M
Operating Cash Flow532.20M455.20M374.94M194.45M669.46M
Investing Cash Flow-189.70M-160.20M20.21M-1.21B-797.38M
Financing Cash Flow-283.20M-218.80M-425.65M973.58M-55.43M

Bio-Rad Laboratories Technical Analysis

Technical Analysis Sentiment
Negative
Last Price271.30
Price Trends
50DMA
302.62
Negative
100DMA
307.71
Negative
200DMA
282.63
Negative
Market Momentum
MACD
-10.08
Positive
RSI
35.84
Neutral
STOCH
37.38
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BIO, the sentiment is Negative. The current price of 271.3 is below the 20-day moving average (MA) of 290.08, below the 50-day MA of 302.62, and below the 200-day MA of 282.63, indicating a bearish trend. The MACD of -10.08 indicates Positive momentum. The RSI at 35.84 is Neutral, neither overbought nor oversold. The STOCH value of 37.38 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for BIO.

Bio-Rad Laboratories Risk Analysis

Bio-Rad Laboratories disclosed 28 risk factors in its most recent earnings report. Bio-Rad Laboratories reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Bio-Rad Laboratories Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
79
Outperform
$45.83B42.600.19%65.58%
71
Outperform
$113.19B39.0512.60%21.62%54.80%
71
Outperform
$28.02B34.5334.50%14.21%5.66%
71
Outperform
$126.27B27.472.76%5.34%13.15%
64
Neutral
$7.26B9.7410.84%-0.88%10.93%
64
Neutral
$29.74B29.523.30%-0.76%-55.03%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BIO
Bio-Rad Laboratories
271.30
-8.85
-3.16%
BSX
Boston Scientific
74.58
-29.81
-28.56%
DXCM
Dexcom
73.08
-17.67
-19.47%
EW
Edwards Lifesciences
79.78
7.02
9.65%
PHG
Koninklijke Philips
31.26
6.06
24.06%
MDT
Medtronic
96.86
9.45
10.81%

Bio-Rad Laboratories Corporate Events

Business Operations and StrategyFinancial Disclosures
Bio-Rad Updates Investors on Sartorius Strategic Investment Metrics
Positive
Feb 19, 2026

Bio-Rad Laboratories provided an update on February 16, 2026, regarding its investment in Sartorius AG by disclosing selected 2025 financial metrics reported by Sartorius. For the year ended December 31, 2025, Sartorius posted €3.54 billion in sales revenue, €542.6 million in EBIT, and €230.4 million in net profit, alongside strong operating cash flow and a solid equity base, offering Bio-Rad stakeholders greater transparency into the financial health of a key strategic holding.

The disclosed Sartorius figures, prepared under IFRS and related standards, highlight a business with substantial non-current assets and a sizeable but balanced liability structure as of year-end 2025. By relaying these data while explicitly disclaiming responsibility for their accuracy, Bio-Rad reinforces its commitment to detailed reporting on significant equity investments without altering its own operational guidance, giving investors additional context for assessing the value and risk profile of its Sartorius stake.

The most recent analyst rating on (BIO) stock is a Hold with a $320.00 price target. To see the full list of analyst forecasts on Bio-Rad Laboratories stock, see the BIO Stock Forecast page.

Business Operations and StrategyExecutive/Board ChangesFinancial DisclosuresM&A Transactions
Bio-Rad Laboratories Posts Mixed Q4 2025 Financial Results
Negative
Feb 12, 2026

Bio-Rad Laboratories reported financial results on February 12, 2026 for the fourth quarter and full year ended December 31, 2025, posting modest revenue growth amid a difficult macro backdrop of geopolitical uncertainty and constrained academic and biotech funding. The Life Science segment saw sales decline for both the quarter and full year on a currency-neutral basis, while the Clinical Diagnostics segment delivered solid growth driven by quality controls, blood typing, and diabetes products, with gains across all regions.

For the fourth quarter, total net sales rose 3.9 percent year over year to $693.2 million, but GAAP gross margin slipped to 49.8 percent and the company recorded a loss from operations, reflecting margin pressure and a $172.8 million impairment of purchased intangibles. Non‑GAAP operating income and margins also declined versus the prior year, underscoring operational headwinds despite revenue gains in diagnostics.

Full-year 2025 revenue inched up 0.7 percent to $2,583.2 million, essentially flat on a currency-neutral basis, as Life Science weakness offset modest Clinical Diagnostics growth. Bio-Rad generated non‑GAAP net income of $270.5 million, down from 2024, but reported a GAAP net income of $759.9 million—versus a large loss in 2024—primarily due to a favorable change in the fair market value of its investment in Sartorius AG, partially offset by the intangibles impairment and a higher effective tax rate.

Strategically, Bio-Rad expanded its Droplet Digital PCR leadership through the acquisition and integration of Stilla Technologies and advanced its oncology diagnostics strategy via partnerships with Gencurix and Biodesix to distribute and develop in vitro diagnostic oncology assays. The company also broadened global access to over 1,200 clinical diagnostics products through new registrations in more than 60 countries, strengthened commercial leadership with the appointment of Rajat Mehta as Executive Vice President of Global Commercial Operations, and delivered $532 million in cash from operations and $375 million in free cash flow.

Looking ahead to full-year 2026, Bio-Rad guided to non‑GAAP, currency-neutral revenue growth of approximately 0.5 to 1.5 percent and an expected non‑GAAP operating margin of about 12.0 to 12.5 percent. This outlook signals a cautious growth trajectory as the company focuses on improving profitability and capitalizing on its expanded ddPCR and oncology diagnostics platforms while navigating funding and reimbursement pressures in its end markets.

The most recent analyst rating on (BIO) stock is a Hold with a $340.00 price target. To see the full list of analyst forecasts on Bio-Rad Laboratories stock, see the BIO Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 21, 2026