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Apogee Therapeutics (APGE)
NASDAQ:APGE
US Market
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Apogee Therapeutics (APGE) AI Stock Analysis

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APGE

Apogee Therapeutics

(NASDAQ:APGE)

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Neutral 61 (OpenAI - 5.2)
Rating:61Neutral
Price Target:
$96.00
▲(4.12% Upside)
Action:ReiteratedDate:03/26/26
The score is held back mainly by pre-revenue status and escalating losses/cash burn, partially offset by a strong, low-leverage balance sheet and a major liquidity boost from the recent equity raise. Technicals are supportive with the stock trading above key moving averages, and corporate events are favorable due to positive clinical readouts.
Positive Factors
Strong balance sheet and very low leverage
A large equity base and minimal debt materially increase strategic optionality for a pre-revenue biotech. This capital structure reduces near-term liquidity stress, supports multi-year clinical programs, and lowers bankruptcy risk versus peers reliant on high leverage while trials progress to value-inflection points.
Negative Factors
Accelerating operating cash burn
Rapidly widening operating and free cash outflows increase reliance on capital markets or partners. Persistently negative cash generation raises dilution or partnership need risk, pressures program pacing, and can force reprioritization of assets if additional non-dilutive funding isn't secured.
Read all positive and negative factors
Positive Factors
Negative Factors
Strong balance sheet and very low leverage
A large equity base and minimal debt materially increase strategic optionality for a pre-revenue biotech. This capital structure reduces near-term liquidity stress, supports multi-year clinical programs, and lowers bankruptcy risk versus peers reliant on high leverage while trials progress to value-inflection points.
Read all positive factors

Apogee Therapeutics (APGE) vs. SPDR S&P 500 ETF (SPY)

Apogee Therapeutics Business Overview & Revenue Model

Company Description
Apogee Therapeutics, Inc., through its subsidiary, operates as a biotechnology company that develops biologics for the treatment of atopic dermatitis (AD), chronic obstructive pulmonary disease (COPD), and related inflammatory and immunology indic...
How the Company Makes Money
Apogee Therapeutics is a clinical-stage company and, based on publicly available information, it does not have a commercialized product portfolio generating recurring product sales. As a result, its revenue, when present, would primarily come from...

Apogee Therapeutics Financial Statement Overview

Summary
Balance sheet is a major strength with very low leverage and a much larger equity base, but the company remains pre-revenue with rapidly widening operating losses and accelerating operating/free cash flow burn, increasing reliance on continued funding.
Income Statement
18
Very Negative
Balance Sheet
82
Very Positive
Cash Flow
26
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022
Income Statement
Total Revenue0.000.000.000.00
Gross Profit-1.42M0.000.000.00
EBITDA-284.18M-216.68M-74.97M-39.78M
Net Income-255.84M-182.15M-83.98M-39.78M
Balance Sheet
Total Assets937.13M753.95M401.40M152.06M
Cash, Cash Equivalents and Short-Term Investments730.19M520.65M395.46M151.89M
Total Debt8.85M11.83M2.03M0.00
Total Liabilities33.25M37.16M21.49M9.98M
Stockholders Equity903.88M716.79M379.91M142.07M
Cash Flow
Free Cash Flow-232.60M-172.33M-74.93M-16.43M
Operating Cash Flow-227.45M-171.17M-74.76M-16.43M
Investing Cash Flow-179.57M-300.46M-273.91M0.00
Financing Cash Flow396.49M495.11M315.39M168.32M

Apogee Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price92.20
Price Trends
50DMA
74.27
Positive
100DMA
74.54
Positive
200DMA
59.26
Positive
Market Momentum
MACD
4.33
Negative
RSI
71.66
Negative
STOCH
93.41
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For APGE, the sentiment is Positive. The current price of 92.2 is above the 20-day moving average (MA) of 81.57, above the 50-day MA of 74.27, and above the 200-day MA of 59.26, indicating a bullish trend. The MACD of 4.33 indicates Negative momentum. The RSI at 71.66 is Negative, neither overbought nor oversold. The STOCH value of 93.41 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for APGE.

Apogee Therapeutics Risk Analysis

Apogee Therapeutics disclosed 70 risk factors in its most recent earnings report. Apogee Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Apogee Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
68
Neutral
$1.91B0.5911.16%
61
Neutral
$6.21B-17.91-36.77%-58.35%
52
Neutral
$2.02B-3.82-31.07%36.26%-158.98%
52
Neutral
$2.83B-26.90-11.10%5376.27%20.97%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$3.54B-43.06-209.33%343.41%11.91%
48
Neutral
$1.94B-71.66%-9.21%-8.84%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
APGE
Apogee Therapeutics
92.20
59.35
180.67%
AGIO
Agios Pharma
35.14
7.80
28.53%
OCUL
Ocular Therapeutix
9.82
2.21
29.04%
GLPG
Galapagos
29.28
4.64
18.83%
LQDA
Liquidia Technologies
39.47
26.18
196.99%
IDYA
IDEAYA Biosciences
33.91
15.73
86.52%

Apogee Therapeutics Corporate Events

Private Placements and FinancingRegulatory Filings and Compliance
Apogee Therapeutics Prices Upsized Public Equity Offering
Positive
Mar 25, 2026
On March 24, 2026, Apogee Therapeutics, Inc. entered into an underwriting agreement with a syndicate led by Jefferies, TD Securities, Stifel and Guggenheim Securities to sell 5,000,000 shares of its common stock at a public offering price of $70.0...
Business Operations and StrategyProduct-Related Announcements
Apogee Therapeutics Announces Positive Phase 2 APEX Maintenance Data
Positive
Mar 23, 2026
On March 23, 2026, Apogee Therapeutics reported positive 52-week maintenance data from Part A of its Phase 2 APEX trial of zumilokibart (APG777) in moderate-to-severe atopic dermatitis, showing durable and deepening clinical responses with 3- and ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 26, 2026