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ACADIA Pharmaceuticals Inc. (ACAD)
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ACADIA Pharmaceuticals (ACAD) AI Stock Analysis

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ACAD

ACADIA Pharmaceuticals

(NASDAQ:ACAD)

Rating:73Outperform
Price Target:
$28.00
▲(11.42% Upside)
ACADIA Pharmaceuticals' overall stock score reflects strong financial performance and positive earnings call insights, with robust revenue growth and strategic initiatives. The valuation is reasonable, although technical analysis is limited due to missing data. The company is well-positioned for future growth, but should monitor SG&A expenses and pipeline risks.
Positive Factors
Product Adoption
Discontinuations remain below 10%, which is very good news for continued growth for this franchise.
Sales Growth
Daybue generated $96.1M in sales, marking 14% year-over-year growth with steady increases in patient uptake and persistency.
Negative Factors
Patient Adoption Challenges
The adoption might be highest among newly diagnosed patients as existing patients and caregiver networks are often educated on risk benefit profile of Daybue from the foundation network or Facebook patient groups which might have adverse effect on the adoption for a proportion of existing patients.
Risk Assessment
There is some risk associated with the upcoming Phase 3 data for ACP-101 in Prader-Willi syndrome, which could affect investor perception.

ACADIA Pharmaceuticals (ACAD) vs. SPDR S&P 500 ETF (SPY)

ACADIA Pharmaceuticals Business Overview & Revenue Model

Company DescriptionACADIA Pharmaceuticals Inc. is a biopharmaceutical company focused on the development and commercialization of innovative medicines to address unmet medical needs in central nervous system disorders. The company is primarily engaged in the research and development of drugs for the treatment of conditions such as Parkinson's disease psychosis and schizophrenia. Its core product, NUPLAZID (pimavanserin), is approved for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis and is marketed in the United States.
How the Company Makes MoneyACADIA Pharmaceuticals generates revenue primarily through the sale of its flagship product, NUPLAZID. The company earns income from product sales to healthcare providers and pharmacies. Additionally, ACADIA may receive milestone payments and royalties from partnerships with other pharmaceutical companies involved in the development and commercialization of complementary therapies. The company also engages in research collaborations and licensing agreements that can provide additional revenue streams. Factors contributing to its earnings include the growth in demand for treatments for CNS disorders, successful marketing strategies, and potential new product approvals or expansions in indications for existing drugs.

ACADIA Pharmaceuticals Key Performance Indicators (KPIs)

Any
Any
Revenue by Product
Revenue by Product
Shows earnings from individual products, highlighting which offerings drive growth and which may need strategic adjustments. This helps assess product portfolio strength and market positioning.
Chart InsightsACADIA Pharmaceuticals is experiencing robust growth in its key products, with NUPLAZID and DAYBUE showing significant revenue increases. NUPLAZID's revenue surged by 23% due to a one-time adjustment, while DAYBUE's sales rose by 11%, despite a sequential decline attributed to seasonality and prior quarter pull-forward. The company is strategically expanding its pipeline and preparing for DAYBUE's European launch, indicating strong future prospects. However, increased R&D expenses and the discontinuation of certain programs highlight ongoing challenges in balancing growth and operational costs.
Data provided by:Main Street Data

ACADIA Pharmaceuticals Earnings Call Summary

Earnings Call Date:Aug 06, 2025
(Q2-2025)
|
% Change Since: 5.59%|
Next Earnings Date:Nov 11, 2025
Earnings Call Sentiment Positive
The earnings call highlighted ACADIA's strong revenue growth driven by DAYBUE and NUPLAZID sales, successful direct-to-consumer campaigns, and a robust pipeline expansion. However, there were concerns about increased SG&A expenses and inherent risks in pipeline development. Overall, the positive aspects of revenue growth and strategic initiatives outweigh the lowlights.
Q2-2025 Updates
Positive Updates
Strong Revenue Growth
ACADIA delivered total revenue of $264.6 million in Q2 2025, up 9% year-over-year, driven by DAYBUE and NUPLAZID sales.
DAYBUE Sales Increase
DAYBUE achieved $96.1 million in sales for Q2 2025, a 14% increase from the previous year, with unique patient shipments increasing.
NUPLAZID Revenue Growth
NUPLAZID's Q2 2025 revenue was $168.5 million, a 7% increase year-over-year, driven by improved prescription volumes.
Pipeline Expansion
ACADIA is advancing its pipeline with 9 disclosed programs, including anticipated Phase II and III studies and readouts from 2025 to 2027.
Successful Direct-to-Consumer Campaigns
The direct-to-consumer campaigns for both DAYBUE and NUPLAZID are driving increased consumer engagement and new prescriptions.
Negative Updates
Increased SG&A Expenses
SG&A expenses rose to $133.5 million in Q2 2025 from $117.1 million the year prior, primarily due to increased expenditures for DAYBUE and NUPLAZID.
Pipeline Development Risks
Ongoing risks and uncertainties associated with pipeline development, including clinical trial outcomes and regulatory approvals.
Company Guidance
During the ACADIA Pharmaceuticals conference call, the company provided financial guidance for 2025, highlighting several key metrics. ACADIA reported total revenue of $264.6 million for Q2, with $96.1 million from DAYBUE and $168.5 million from NUPLAZID. The company raised the lower end of its full-year NUPLAZID revenue guidance to $665-$690 million, reflecting strong commercial execution and positive momentum from a direct-to-consumer campaign. DAYBUE's sales grew by 14% year-over-year, with a 12-month persistency rate exceeding 50%. The call also noted a strategic expansion beyond Centers of Excellence, with 900 healthcare providers now prescribing DAYBUE. ACADIA's R&D pipeline includes nine disclosed programs, with expectations to initiate seven Phase II or III studies in 2025 and 2026, and five data readouts anticipated between 2025 and 2027. The company ended the quarter with a cash balance of $762 million and maintained confidence in achieving its financial targets, driven by disciplined execution and ongoing growth initiatives.

ACADIA Pharmaceuticals Financial Statement Overview

Summary
ACADIA Pharmaceuticals shows strong financial health with consistent revenue growth, improved profitability, and positive cash flows. The balance sheet reflects stability with minimal leverage, and the overall financial performance indicates a positive outlook. Continued focus on maintaining profitability and managing debt levels will be crucial for sustaining this momentum.
Income Statement
85
Very Positive
The company has shown impressive revenue growth with a TTM (Trailing-Twelve-Months) revenue of $996.3 million, up from $957.8 million in the previous year, indicating a strong upward trajectory. The gross profit margin remains robust at approximately 92.0%, reflecting efficient cost management. Net profit margin has improved significantly, turning positive, which highlights enhanced profitability. EBIT and EBITDA margins are also positive, further emphasizing operational improvements.
Balance Sheet
78
Positive
ACADIA Pharmaceuticals demonstrates a healthy balance sheet with a low debt-to-equity ratio, suggesting prudent financial management. The equity ratio is high, indicating a strong reliance on equity financing. Return on Equity (ROE) is positive and improving, showcasing the company's ability to generate returns on shareholders' investments. However, the company's debt levels, while manageable, should be monitored as they have increased slightly.
Cash Flow
80
Positive
The company has achieved positive free cash flow, marking a significant improvement from previous years. Operating cash flow to net income ratio is healthy, suggesting effective cash management. While the free cash flow growth rate has declined slightly in the latest TTM period compared to the previous year, the overall cash flow position is solid, supporting future growth initiatives.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue1.02B957.80M726.44M517.24M484.14M441.75M
Gross Profit937.10M875.96M680.71M507.07M465.00M421.20M
EBITDA106.30M100.16M-67.83M-221.57M-167.09M-286.59M
Net Income222.16M226.45M-61.29M-215.97M-167.87M-281.58M
Balance Sheet
Total Assets1.23B1.19B748.96M587.81M700.12M782.62M
Cash, Cash Equivalents and Short-Term Investments762.00M755.99M438.87M416.82M520.71M631.96M
Total Debt44.60M51.99M57.20M62.00M56.13M44.46M
Total Liabilities403.17M454.96M317.20M187.40M159.23M155.61M
Stockholders Equity822.38M732.79M431.75M400.41M540.89M627.01M
Cash Flow
Free Cash Flow187.09M157.20M-23.35M-114.03M-126.78M-143.75M
Operating Cash Flow187.91M157.72M16.70M-114.03M-125.66M-136.17M
Investing Cash Flow-127.65M-30.54M32.00M73.24M-71.10M192.51M
Financing Cash Flow20.03M6.84M25.13M8.20M18.16M81.00M

ACADIA Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Positive
Last Price25.13
Price Trends
50DMA
22.59
Positive
100DMA
19.80
Positive
200DMA
18.65
Positive
Market Momentum
MACD
0.80
Negative
RSI
67.96
Neutral
STOCH
81.95
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ACAD, the sentiment is Positive. The current price of 25.13 is above the 20-day moving average (MA) of 23.58, above the 50-day MA of 22.59, and above the 200-day MA of 18.65, indicating a bullish trend. The MACD of 0.80 indicates Negative momentum. The RSI at 67.96 is Neutral, neither overbought nor oversold. The STOCH value of 81.95 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for ACAD.

ACADIA Pharmaceuticals Risk Analysis

ACADIA Pharmaceuticals disclosed 55 risk factors in its most recent earnings report. ACADIA Pharmaceuticals reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

ACADIA Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
73
Outperform
$4.29B18.8833.18%14.41%627.78%
62
Neutral
$4.82B-48.54%59.77%-92.92%
58
Neutral
$3.02B-108.49%20.02%33.45%
51
Neutral
$7.43B-0.36-45.45%2.27%22.98%-2.34%
49
Neutral
$2.33B78.99%4227.22%50.80%
45
Neutral
$2.65B-77.58%-48.38%
41
Neutral
$3.52B-40.29%-208.46%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ACAD
ACADIA Pharmaceuticals
25.13
9.99
65.98%
IBRX
ImmunityBio
2.82
-1.06
-27.32%
MRUS
Merus
67.09
16.53
32.69%
APLS
Apellis Pharmaceuticals
26.58
-9.44
-26.21%
IMVT
Immunovant
15.89
-14.27
-47.31%
MLTX
MoonLake Immunotherapeutics
55.65
8.65
18.40%

ACADIA Pharmaceuticals Corporate Events

Legal Proceedings
Acadia Pharmaceuticals Wins Patent Case for NUPLAZID
Positive
Jun 10, 2025

On June 9, 2025, Acadia Pharmaceuticals announced that the U.S. Court of Appeals for the Federal Circuit upheld a previous decision by the U.S. District Court for the District of Delaware, confirming the validity of the company’s composition of matter patent for NUPLAZID® (pimavanserin). This legal victory against MSN Laboratories and its affiliate MSN Pharmaceuticals reinforces Acadia’s patent position, potentially strengthening its market position and providing assurance to stakeholders regarding the protection of its intellectual property.

The most recent analyst rating on (ACAD) stock is a Hold with a $20.00 price target. To see the full list of analyst forecasts on ACADIA Pharmaceuticals stock, see the ACAD Stock Forecast page.

Executive/Board ChangesShareholder Meetings
Acadia Pharmaceuticals Holds 2025 Annual Stockholder Meeting
Neutral
May 29, 2025

On May 29, 2025, Acadia Pharmaceuticals Inc. held its 2025 Annual Meeting of Stockholders, where three Class III directors were elected to the Board of Directors to serve until the 2028 Annual Meeting. Additionally, stockholders approved the compensation of the company’s named executive officers and ratified the appointment of Ernst & Young LLP as the independent registered public accounting firm for the fiscal year ending December 31, 2025.

The most recent analyst rating on (ACAD) stock is a Hold with a $20.00 price target. To see the full list of analyst forecasts on ACADIA Pharmaceuticals stock, see the ACAD Stock Forecast page.

Legal ProceedingsBusiness Operations and Strategy
ACADIA Pharmaceuticals Wins Favorable Patent Court Ruling
Positive
May 20, 2025

On May 15, 2025, ACADIA Pharmaceuticals entered into a 12-year lease agreement for new executive office space at 210 Carnegie Center in Princeton, New Jersey, with plans for commercial, research, and development activities. The company will pay an initial annual rent of $1,899,756, with incremental increases, and is responsible for operating expenses and property taxes. Additionally, ACADIA announced a favorable court ruling on May 16, 2025, regarding its formulation patent for NUPLAZID®, securing its position against competitors Aurobindo Pharma and MSN Laboratories.

The most recent analyst rating on (ACAD) stock is a Hold with a $20.00 price target. To see the full list of analyst forecasts on ACADIA Pharmaceuticals stock, see the ACAD Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 14, 2025