Key RisksKey risks include failed or equivocal studies, unforeseen safety or tolerability issues, meaningful delays, and the inability to sufficiently fund operations.
Restructuring CostsArbutus anticipates a one-time restructuring charge of ~$11M-$13M in 1Q25.
Trial DiscontinuationArbutus has discontinued the planned IM-PROVE III Phase 2a trial of imdusiran plus anti-PD-L1 antibody durvalumab prior to initiation.