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PRAX Stock Chart & Stats
$325.30
-$9.50(-2.92%)
At close: 4:00 PM EDT
$325.30
-$9.50(-2.92%)
Day’s Range― - ―
52-Week Range$37.19 - $392.70
Previous Close$315.8
Volume296.03K
Average Volume (3M)493.75K
Market Cap
$10.50B
Enterprise Value$9.00K
Total Cash (Recent Filing)$758.55M
Total Debt (Recent Filing)$1.09M
Price to Earnings (P/E)―
Beta2.19
Next Earnings
Nov 11, 2026EPS Estimate
-3.53Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-12.95
Shares Outstanding27,919,989
10 Day Avg. Volume281,120
30 Day Avg. Volume493,747
Financial Highlights & Ratios
PEG Ratio-0.68
Price to Book (P/B)7.55
Price to Sales (P/S)0.00
P/FCF Ratio-26.63
Enterprise Value/Market Cap<0.01
Enterprise Value/RevenueN/A
Enterprise Value/Gross Profit>-0.01
Enterprise Value/Ebitda>-0.01
Forecast
1Y Price Target
$639.33Price Target Upside96.54% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering18
EPS Forecast (FY)-13.6
Revenue Forecast (FY)$891.86K
Bulls Say, Bears Say
Bulls Say
Late-stage Regulatory ProgressFavorable FDA feedback on two late-stage applications materially reduces regulatory uncertainty and supports potential transition from clinical development to commercial operations, while the absence of advisory committees may simplify the approval process.
Strong Balance Sheet And RunwaySubstantial liquidity and minimal debt provide financial flexibility to fund regulatory work, launch preparation and pipeline development without immediate balance-sheet pressure, giving Praxis time to pursue commercialization before requiring additional capital.
Commercial Infrastructure And Pipeline DepthEstablished launch capabilities can support execution if approvals arrive, while the broader pipeline adds potential growth beyond the initial products. Breakthrough status for elsunersen may accelerate development in a high-unmet-need pediatric epilepsy segment.
Bears Say
No Durable Revenue BasePraxis remains dependent on successful regulatory approvals and future commercialization because it currently lacks recurring product revenue. Large operating losses limit internal funding capacity and leave results highly exposed to development and launch execution.
Persistent Cash BurnSustained negative cash generation reflects the cost of advancing multiple programs and preparing for launches. Although liquidity is strong today, continued burn could reduce flexibility and increase dependence on future financing or successful commercial revenue.
Clinical And Regulatory Execution RiskThe primary-endpoint miss requires protocol amendments and a restart, adding time, cost and uncertainty to the pipeline. Separately, the relutrigine review extension creates approval-timing risk that could delay revenue generation and launch planning.
PRAX FAQ
What was Praxis Precision Medicines’s price range in the past 12 months?
Praxis Precision Medicines lowest stock price was $37.19 and its highest was $392.70 in the past 12 months.
What is Praxis Precision Medicines’s market cap?
Praxis Precision Medicines’s market cap is $10.50B.
When is Praxis Precision Medicines’s upcoming earnings report date?
Praxis Precision Medicines’s upcoming earnings report date is Nov 11, 2026 which is in 79 days.
How were Praxis Precision Medicines’s earnings last quarter?
Praxis Precision Medicines released its earnings results on Aug 06, 2026. The company reported -$2.87 earnings per share for the quarter, beating the consensus estimate of -$3.668 by $0.798.
Is Praxis Precision Medicines overvalued?
According to Wall Street analysts Praxis Precision Medicines’s price is currently Undervalued.
Does Praxis Precision Medicines pay dividends?
Praxis Precision Medicines does not currently pay dividends.
What is Praxis Precision Medicines’s EPS estimate?
Praxis Precision Medicines’s EPS estimate is -3.53.
How many shares outstanding does Praxis Precision Medicines have?
Praxis Precision Medicines has 27,919,989 shares outstanding.
What happened to Praxis Precision Medicines’s price movement after its last earnings report?
Praxis Precision Medicines reported an EPS of -$2.87 in its last earnings report, beating expectations of -$3.668. Following the earnings report the stock price went up 15.954%.
Which hedge fund is a major shareholder of Praxis Precision Medicines?
Currently, no hedge funds are holding shares in PRAX
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Praxis Precision Medicines Stock Smart Score
Neutral
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Analyst Consensus
Strong Buy
Average Price Target:
$639.33 (96.54% Upside)
$639.33 (96.54% Upside)
Blogger Sentiment
Bullish
PRAX Sentiment 100%
Sector Average 60%
Sector Average 60%
Hedge Fund Trend
Decreased
By 355.4K Shares
Last Quarter.
Last Quarter.
Crowd Wisdom
Very Negative
Last 7 Days ▼ 1.3%
Last 30 Days ▼ 2.9%
Last 30 Days ▼ 2.9%
News Sentiment
Very Bullish
Bullish news 80%
Bearish news 20%
Bearish news 20%
Technicals
SMA
Positive
20 days / 200 days
Momentum
460.81%
12-Months-Change
Fundamentals
Return on Equity
―
Trailing 12-Months
Asset Growth
206.98%
Trailing 12-Months
Company Description
Praxis Precision Medicines
Praxis Precision Medicines, Inc. is a biopharmaceutical firm operating at the clinical stage, dedicated to creating innovative treatments for central nervous system (CNS) conditions that stem from an imbalance in neuronal activity. The company's primary investigational compounds currently undergoing evaluation include: PRAX-114, an extrasynaptic-preferring positive allosteric modulator of the GABAA receptor, which is currently in Phase IIa clinical trials for addressing both major depressive disorder and perimenopausal depression. Additionally, PRAX-944, a small molecule designed to selectively inhibit T-type calcium channels, is also progressing through Phase IIa clinical trials to manage essential tremor. Beyond these, Praxis is also advancing a pipeline of other promising drug candidates, such as: PRAX-562, a persistent sodium current blocker, undergoing Phase I clinical evaluation for treating severe pediatric epilepsy and adult cephalgia (headaches). PRAX-222, an antisense oligonucleotide (ASO) aimed at individuals suffering from gain-of-function (GOF) SCN2A epilepsy. And a program targeting KCNT1 for the treatment of KCNT1 GOF epilepsy. To further its research and development efforts, Praxis maintains several strategic alliances. These include a cooperation and licensing arrangement with RogCon Inc.; a licensing deal with Purdue Neuroscience Company; a comprehensive research collaboration, option, and license agreement with Ionis Pharmaceuticals, Inc.; and a collaborative project with The Florey Institute focused on the creation of three new antisense oligonucleotides (ASOs). Established in 2015, the company's headquarters are situated in Boston, Massachusetts.
PRAX Earnings Call
Q2 2026
0:00 / 0:00
Earnings Call Sentiment|Positive
The call showed strong positive momentum: two late-stage NDAs with favorable FDA mid-cycle feedback and no advisory committees, a clean FDA BIMO inspection, solid commercial build and a robust cash position providing runway into 2028. Clinical progress was highlighted by EMERALD over-enrollment and another BTD for elsunersen. Offsetting risks include a failed primary in vormatrigine (being addressed by redesign), higher near-term operating spend and a relutrigine review extension. On balance, the significant regulatory, commercial and financial positives outweigh the operational and clinical setbacks.View all PRAX earnings summariesPRAX Stock 12 Month Forecast
Average Price Target
$639.33
▲(96.54% Upside)
Technical Analysis
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Ownership Overview
8.06% Insiders
25.16% Mutual Funds
47.98% Other Institutional Investors
2.01% Public Companies and Individual Investors








