tiprankstipranks
Trending News
More News >
Xeris Pharmaceuticals (XERS)
:XERS
Advertisement

Xeris Pharmaceuticals (XERS) AI Stock Analysis

Compare
1,059 Followers

Top Page

XERS

Xeris Pharmaceuticals

(NASDAQ:XERS)

Select Model
Select Model
Select Model
Neutral 51 (OpenAI - 4o)
Rating:51Neutral
Price Target:
$7.50
▼(-17.40% Downside)
Xeris Pharmaceuticals shows promising revenue growth and positive earnings call highlights, which are significant strengths. However, the company's financial performance is hindered by profitability and cash flow challenges, high leverage, and a negative equity position. The technical analysis suggests potential for a rebound, but valuation remains unattractive due to ongoing losses. Overall, the stock presents a mixed outlook with notable risks and opportunities.
Positive Factors
Revenue Growth
The strong revenue growth indicates robust demand for Xeris's products, suggesting effective market penetration and product acceptance, which is crucial for long-term sustainability.
Product Performance
RECORLEV's significant revenue growth underscores its market potential and strengthens Xeris's competitive position, supporting future expansion and profitability.
Cash Flow and Profitability
Achieving positive cash flow and net income marks a critical milestone, enhancing financial stability and enabling reinvestment in growth initiatives.
Negative Factors
High Leverage
High leverage and negative equity pose financial risks, limiting flexibility and increasing vulnerability to economic downturns, which could hinder long-term growth.
Profitability Challenges
Ongoing profitability challenges indicate cost structure inefficiencies, which could impact the company's ability to sustain growth and invest in new opportunities.
Cash Flow Management
Declining free cash flow growth highlights cash management issues, potentially affecting the company's ability to fund operations and strategic initiatives.

Xeris Pharmaceuticals (XERS) vs. SPDR S&P 500 ETF (SPY)

Xeris Pharmaceuticals Business Overview & Revenue Model

Company DescriptionXeris Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing and commercializing innovative therapies for patients with chronic diseases. The company specializes in the delivery of biologics and has developed a proprietary formulation technology that enables the stable, room-temperature storage of biologics, which helps improve patient compliance and convenience. Xeris's core products include Gvoke, an injectable glucagon for the treatment of severe hypoglycemia, and other potential therapies aimed at addressing unmet medical needs in diabetes and other chronic conditions.
How the Company Makes MoneyXeris Pharmaceuticals generates revenue primarily through the sales of its products, particularly Gvoke, which is marketed for the emergency treatment of severe hypoglycemia in patients with diabetes. The company also earns revenue through partnerships and collaborations with other pharmaceutical companies, which may include licensing agreements, milestone payments, and royalties from product sales. Additionally, Xeris may explore opportunities in research and development agreements that can provide further financial support through funding or shared revenues from new therapies developed using its proprietary technology.

Xeris Pharmaceuticals Earnings Call Summary

Earnings Call Date:Nov 06, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 11, 2026
Earnings Call Sentiment Positive
The earnings call highlighted Xeris Biopharma's strong financial performance with record revenue growth and successful product performance, particularly for RECORLEV. However, there are increased expenses and potential competitive challenges on the horizon. Despite these concerns, the company's positive financial milestones and strategic growth plans suggest an optimistic outlook.
Q3-2025 Updates
Positive Updates
Record-Breaking Revenue Growth
Total product revenue exceeded $74 million, representing a 40% increase year-over-year. The full year total revenue guidance was raised to be in the range of $285 million to $290 million, a 42% increase at the midpoint.
RECORLEV Performance
RECORLEV remained the primary growth engine with revenue of $37 million in the quarter, a year-over-year increase of 109%. The average number of patients on therapy grew by 108% versus the same period last year.
Gvoke and KEVEYIS Performance
Gvoke delivered a solid quarter with revenue of more than $25 million, up nearly 10% from the same period last year. KEVEYIS revenue was approximately $12 million, driven by growth in the average number of patients on therapy.
Financial Milestones
The company generated significant positive cash flow and net income for the first time in its history. Adjusted EBITDA for the quarter was $17.4 million, improving more than $20 million compared to Q3 2024.
Negative Updates
Increased Expenses
R&D expenses increased by $1.6 million compared to the previous year, primarily due to continued investment in the pipeline and technology platforms. SG&A expenses also rose by approximately 3% due to incremental personnel-related expenses.
Potential Impact of Competition
There is anticipation of new competition from Corcept's relacorilant, which could impact RECORLEV, though the company remains optimistic about overall market growth.
Company Guidance
During the Xeris Biopharma Q3 2025 earnings call, the company provided robust guidance, highlighting a record-setting quarter with total product revenue exceeding $74 million, marking a 40% year-over-year increase. The company raised the lower end of its full-year total revenue guidance to between $285 million and $290 million, reflecting a 42% increase at the midpoint compared to 2024. Key metrics driving this growth included a 109% increase in RECORLEV revenue, reaching $37 million, and a 108% rise in the average number of patients on RECORLEV therapy. Gvoke's revenue was over $25 million, up nearly 10% year-over-year, while KEVEYIS generated approximately $12 million, driven by new patient additions. Additionally, the company reported improving gross margins at 85%, significant positive cash flow, and net income for the first time. Looking forward, Xeris plans strategic investments in its RECORLEV commercial organization and the development of XP-8121, aiming to maintain positive adjusted EBITDA amidst a continued focus on scalable growth.

Xeris Pharmaceuticals Financial Statement Overview

Summary
Xeris Pharmaceuticals is experiencing revenue growth but faces significant profitability and cash flow challenges. The high leverage and negative equity position present financial risks. While revenue is increasing, the company needs to address its cost structure and improve cash flow management to enhance financial health.
Income Statement
45
Neutral
Xeris Pharmaceuticals has shown a positive revenue growth rate of 10.55% in the TTM, indicating a growing top line. However, the company is struggling with profitability, as evidenced by negative net profit and EBIT margins. The gross profit margin has decreased significantly from 81.86% in 2024 to 37.11% in the TTM, reflecting increased cost pressures or pricing challenges.
Balance Sheet
30
Negative
The balance sheet reveals high leverage with a negative equity position, resulting in a concerning debt-to-equity ratio of -13.32 in the TTM. The negative return on equity indicates that the company is not generating profits from its equity base, posing a risk to financial stability.
Cash Flow
40
Negative
Cash flow analysis shows a significant decline in free cash flow growth by -75.8% in the TTM, indicating cash management challenges. The operating cash flow to net income ratio is negative, suggesting inefficiencies in converting income into cash. However, the free cash flow to net income ratio is slightly above 1, indicating that free cash flow is covering net losses.
BreakdownTTMDec 2024Dec 2023Dec 2023Dec 2023Dec 2023
Income Statement
Total Revenue266.14M203.07M163.91M163.91M163.91M163.91M
Gross Profit158.94M166.24M135.27M135.27M135.27M135.27M
EBITDA22.28M-11.30M-23.73M-23.73M-23.73M-23.73M
Net Income-15.64M-54.84M-62.26M-62.26M-62.26M-62.26M
Balance Sheet
Total Assets370.19M323.06M322.60M322.60M322.60M322.60M
Cash, Cash Equivalents and Short-Term Investments91.60M71.62M72.45M72.45M72.45M72.45M
Total Debt38.19M271.45M229.19M229.19M229.19M229.19M
Total Liabilities371.05M352.68M329.38M329.38M329.38M329.38M
Stockholders Equity-861.00K-29.61M-6.78M-6.78M-6.78M-6.78M
Cash Flow
Free Cash Flow19.82M-37.85M-49.29M-49.29M-49.29M-49.29M
Operating Cash Flow10.56M-36.98M-47.02M-47.02M-47.02M-47.02M
Investing Cash Flow9.65M4.88M-6.00M-6.00M-6.00M-6.00M
Financing Cash Flow12.05M36.17M-1.61M-1.61M-1.61M-1.61M

Xeris Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Negative
Last Price9.08
Price Trends
50DMA
8.39
Negative
100DMA
7.10
Positive
200DMA
5.76
Positive
Market Momentum
MACD
0.12
Positive
RSI
31.22
Neutral
STOCH
38.45
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For XERS, the sentiment is Negative. The current price of 9.08 is below the 20-day moving average (MA) of 9.10, above the 50-day MA of 8.39, and above the 200-day MA of 5.76, indicating a neutral trend. The MACD of 0.12 indicates Positive momentum. The RSI at 31.22 is Neutral, neither overbought nor oversold. The STOCH value of 38.45 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for XERS.

Xeris Pharmaceuticals Risk Analysis

Xeris Pharmaceuticals disclosed 83 risk factors in its most recent earnings report. Xeris Pharmaceuticals reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Xeris Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
59
Neutral
$1.30B34.0515.02%1128.17%
56
Neutral
$2.44B-68.13%-8.75%-8.79%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$1.59B42.05%76.50%
48
Neutral
$1.37B-19.89%95.94%35.69%
48
Neutral
$1.31B-129.32%597.19%0.45%
44
Neutral
$1.21B-23.41%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
XERS
Xeris Pharmaceuticals
7.43
3.96
114.12%
SNDX
Syndax Pharmaceuticals
15.04
-6.77
-31.04%
ZYME
Zymeworks
16.46
-0.17
-1.02%
RCUS
Arcus Biosciences
19.31
1.46
8.18%
STOK
Stoke Therapeutics
22.86
8.98
64.70%
RAPP
Rapport Therapeutics, Inc.
25.66
-1.03
-3.86%

Xeris Pharmaceuticals Corporate Events

Xeris Biopharma Reports Strong Q3 2025 Financial Results
Nov 7, 2025

Xeris Biopharma Holdings, Inc. is a rapidly expanding biopharmaceutical company dedicated to enhancing patient lives through the development and commercialization of innovative therapeutic products. The company operates in the healthcare sector, with a focus on treatments for conditions such as endogenous Cushing’s syndrome, severe hypoglycemia, and primary periodic paralysis.

Xeris Biopharma Reports Record Revenue Growth in Earnings Call
Nov 7, 2025

Xeris Biopharma’s recent earnings call painted a picture of robust financial health and strategic optimism. The company reported record revenue growth, driven by strong product performance, particularly from RECORLEV. Despite facing increased expenses and potential competitive pressures, Xeris remains confident in its strategic growth plans and financial milestones, suggesting a positive outlook.

Xeris Pharmaceuticals Reports Record Revenue and Growth
Aug 13, 2025

Xeris Pharmaceuticals’ recent earnings call painted a picture of robust financial health and promising growth prospects. The company reported a record-breaking quarter with significant revenue growth and increased demand for its key products, particularly Recorlev. Despite some challenges, such as increased expenses and a slight decline in gross margin, the overall sentiment was positive, with raised revenue guidance and a favorable adjusted EBITDA.

Xeris Biopharma Reports Strong Q2 2025 Results
Aug 8, 2025

Xeris Biopharma Holdings, Inc., a biopharmaceutical company based in Chicago, focuses on developing and commercializing innovative therapies, including products like Recorlev, Gvoke, and Keveyis, with a robust pipeline of development programs.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 07, 2025