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AbCellera Biologics (ABCL)
NASDAQ:ABCL
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AbCellera Biologics (ABCL) AI Stock Analysis

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ABCL

AbCellera Biologics

(NASDAQ:ABCL)

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Neutral 41 (OpenAI - 4o)
Rating:41Neutral
Price Target:
$3.50
▼(-10.49% Downside)
AbCellera Biologics faces significant financial and technical challenges, with negative profitability and bearish technical indicators. The company's strategic shift towards clinical-stage biotech offers potential long-term growth, but current financial metrics and market sentiment are weak.
Positive Factors
Strong Liquidity Position
A strong liquidity position with $750 million available provides financial flexibility to invest in R&D and clinical trials, supporting long-term growth.
Pipeline Expansion
Expanding the pipeline with new programs like ABCL688 indicates a robust R&D strategy, potentially leading to future revenue streams and market expansion.
Leadership Strength
The new CMO brings over two decades of experience, enhancing leadership quality and potentially accelerating clinical development and regulatory approvals.
Negative Factors
Declining Profitability
Ongoing net losses highlight challenges in achieving profitability, which may affect financial sustainability and investor confidence if not addressed.
Negative Cash Flow
Negative cash flows indicate operational inefficiencies and could limit the company's ability to fund future growth and R&D initiatives without external financing.
Decreased R&D Expenses
Reduced R&D spending may slow innovation and pipeline development, potentially impacting long-term competitive positioning and growth prospects.

AbCellera Biologics (ABCL) vs. SPDR S&P 500 ETF (SPY)

AbCellera Biologics Business Overview & Revenue Model

Company DescriptionAbCellera Biologics (ABCL) is a biotechnology company based in Canada, specializing in the discovery and development of monoclonal antibodies. The company leverages its innovative technology platform, which combines high-throughput screening and machine learning, to identify and optimize antibodies for various therapeutic applications. AbCellera collaborates with pharmaceutical and biotechnology companies to accelerate the development of antibody-based therapies, contributing to advancements in the treatment of diseases such as cancer and autoimmune disorders.
How the Company Makes MoneyAbCellera generates revenue primarily through its partnerships and collaborations with pharmaceutical companies, where it provides its antibody discovery services. The company typically enters into agreements that include upfront payments, research funding, and milestone payments based on the progress of drug development. Additionally, AbCellera may receive royalties on sales of products that result from these collaborations. The company's revenue model is heavily reliant on the successful advancement of its partners' therapeutic candidates, along with ongoing research contracts and collaborations that can provide continuous income streams.

AbCellera Biologics Key Performance Indicators (KPIs)

Any
Any
Number of Discovery Partners
Number of Discovery Partners
Indicates the breadth of AbCellera's collaborative network, highlighting potential for diverse innovation and revenue streams through partnerships.
Chart InsightsAbCellera's number of discovery partners has grown steadily, reaching 46 by the end of 2023. However, the latest earnings call reveals a strategic shift with reduced new partnership activities, focusing instead on advancing clinical programs like ABCL635 and ABCL575. This pivot to a clinical stage biotech, despite declining revenue and increased R&D expenses, suggests a long-term strategy prioritizing high-value partnerships and clinical advancements over sheer volume of discovery collaborations.
Data provided by:Main Street Data

AbCellera Biologics Earnings Call Summary

Earnings Call Date:Nov 06, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Feb 24, 2026
Earnings Call Sentiment Positive
The earnings call highlighted significant progress in clinical trials and a strong financial position, with increased revenue and continued pipeline expansion. However, the company also reported a net loss, though slightly improved from the previous year, and a decrease in R&D expenses.
Q2-2025 Updates
Positive Updates
Health Canada Authorization and Clinical Trials Initiation
AbCellera received Health Canada authorization to initiate their first two clinical trials for ABCL635 and ABCL575. Dosing has begun for ABCL635's Phase I trial evaluating its efficacy for vasomotor symptoms.
Strong Financial Position
AbCellera ended the quarter with approximately $750 million in available liquidity, including $580 million in cash and equivalents, and $170 million in committed government funding.
Pipeline Expansion
AbCellera advanced a third program, ABCL688, into IND-enabling studies and plans to advance at least one more development candidate by the end of 2025.
Revenue Growth
The company reported revenue of approximately $17 million for the quarter, up from $7 million in the same quarter of 2024.
Negative Updates
Net Loss for the Quarter
AbCellera reported a net loss of approximately $35 million for the quarter, compared to a loss of $37 million in the same quarter last year.
Decreased Research and Development Expenses
R&D expenses for the quarter were approximately $39 million, $2 million less than last year, reflecting the timing of larger program-specific expenses.
Company Guidance
During AbCellera's Second Quarter 2025 Business Update Conference Call, the company provided comprehensive guidance on its clinical and financial progress. Key highlights included the initiation of Phase I clinical trials for two lead antibody candidates, ABCL635 and ABCL575, with Health Canada authorization. ABCL635 targets moderate to severe vasomotor symptoms, with a primary endpoint of safety and a secondary endpoint of pharmacokinetics, while ABCL575 focuses on atopic dermatitis with potential in broader autoimmune indications. The company reported approximately $750 million in available liquidity, including $580 million in cash and equivalents. Revenue for the quarter was approximately $17 million, a significant increase from $7 million in the same quarter of 2024, largely due to a one-off $10 million licensing fee. AbCellera anticipates initial safety and efficacy data for ABCL635 by mid-2026 and aims to advance additional candidates into IND-enabling studies, with ongoing investments in clinical manufacturing capabilities set to come online by the end of 2025.

AbCellera Biologics Financial Statement Overview

Summary
AbCellera Biologics is experiencing revenue growth but faces challenges with profitability and cash flow. The company has a low debt-to-equity ratio, providing financial flexibility, but persistent losses and negative cash flows highlight the need for strategic improvements.
Income Statement
35
Negative
AbCellera Biologics has experienced significant volatility in its revenue and profitability. The company showed strong revenue growth in the TTM period with a 42.23% increase, but this was accompanied by negative gross and net profit margins, indicating challenges in cost management and profitability. Historical data shows a declining trend in revenue and profit margins, which raises concerns about the company's ability to sustain growth and profitability.
Balance Sheet
50
Neutral
The balance sheet of AbCellera Biologics shows a relatively low debt-to-equity ratio, indicating conservative leverage. However, the return on equity has been negative in recent periods, reflecting ongoing losses. The equity ratio remains stable, suggesting a solid capital structure, but the negative ROE highlights the need for improved operational performance to enhance shareholder value.
Cash Flow
40
Negative
AbCellera Biologics faces challenges in cash flow management, with negative operating and free cash flows in recent periods. The free cash flow to net income ratio is positive, indicating some efficiency in converting earnings to cash, but the overall cash flow position is weak. The company needs to address its cash burn to ensure long-term sustainability.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue35.32M28.83M38.02M485.42M375.20M233.16M
Gross Profit19.31M28.83M38.02M418.99M329.69M206.01M
EBITDA-209.57M-204.15M-192.16M260.17M239.15M169.62M
Net Income-171.68M-162.86M-146.40M158.52M153.46M118.92M
Balance Sheet
Total Assets1.36B1.36B1.49B1.54B1.32B1.01B
Cash, Cash Equivalents and Short-Term Investments520.67M625.61M760.59M886.49M722.98M594.12M
Total Debt137.05M65.36M77.38M82.26M40.06M6.78M
Total Liabilities391.95M304.47M335.78M307.63M292.84M175.03M
Stockholders Equity964.04M1.06B1.15B1.23B1.03B830.51M
Cash Flow
Free Cash Flow-153.11M-186.95M-121.38M204.70M186.13M8.02M
Operating Cash Flow-104.55M-108.56M-43.88M277.36M244.58M22.69M
Investing Cash Flow48.31M121.41M-221.11M-352.63M-332.25M-119.78M
Financing Cash Flow14.11M12.77M10.36M-1.63M-3.89M683.65M

AbCellera Biologics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3.91
Price Trends
50DMA
5.09
Negative
100DMA
4.66
Negative
200DMA
3.60
Positive
Market Momentum
MACD
-0.20
Positive
RSI
28.50
Positive
STOCH
11.13
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ABCL, the sentiment is Negative. The current price of 3.91 is below the 20-day moving average (MA) of 5.42, below the 50-day MA of 5.09, and above the 200-day MA of 3.60, indicating a neutral trend. The MACD of -0.20 indicates Positive momentum. The RSI at 28.50 is Positive, neither overbought nor oversold. The STOCH value of 11.13 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ABCL.

AbCellera Biologics Risk Analysis

AbCellera Biologics disclosed 102 risk factors in its most recent earnings report. AbCellera Biologics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

AbCellera Biologics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$2.39B-68.13%-8.75%-8.79%
55
Neutral
$1.32B-10.20-28.57%-42.64%-39.78%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$1.31B-129.32%597.19%0.45%
41
Neutral
$1.17B-16.81%7.16%3.95%
40
Underperform
$1.82B-30.02%-5.73%
31
Underperform
$1.99B-25.31%-64.91%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ABCL
AbCellera Biologics
3.91
0.76
24.13%
SNDX
Syndax Pharmaceuticals
15.04
-6.74
-30.95%
RCUS
Arcus Biosciences
19.31
1.56
8.79%
DNTH
Dianthus Therapeutics
36.28
8.53
30.74%
EWTX
Edgewise Therapeutics
17.16
-18.17
-51.43%
GPCR
Structure Therapeutics, Inc. Sponsored ADR
32.84
-5.86
-15.14%

AbCellera Biologics Corporate Events

AbCellera Biologics Reports Q3 2025 Financial Results
Nov 7, 2025

AbCellera Biologics Inc. is a clinical-stage biotechnology company specializing in the discovery and development of antibody-based medicines across various therapeutic areas, including endocrinology, women’s health, immunology, and oncology.

Business Operations and StrategyExecutive/Board ChangesFinancial Disclosures
AbCellera Biologics Reports Q3 2025 Financial Results
Neutral
Nov 6, 2025

AbCellera Biologics reported its financial results for the third quarter of 2025, highlighting the start of activities at its new clinical manufacturing facility and substantial completion of platform investments. The company ended the quarter with $680 million in available liquidity, despite a net loss of $57.1 million. Key developments included the appointment of a new Chief Medical Officer and progress in Phase 1 clinical trials for its lead programs. The company also reported an increase in partner-initiated program starts and molecules advanced into the clinic, reflecting its strategic focus on expanding its pipeline.

The most recent analyst rating on (ABCL) stock is a Hold with a $5.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

AbCellera’s ABCL635 Study: A Promising Step for Menopause Treatment
Oct 27, 2025

AbCellera Biologics Inc. is conducting a Phase 1 clinical study titled ‘A First-in-Human Phase 1 Study of ABCL635 in Healthy Participants and in Postmenopausal Women With Moderate-to-Severe Vasomotor Symptoms’. The study aims to evaluate the effects of ABCL635, a biological intervention, on vasomotor symptoms (VMS) associated with menopause, focusing on safety, tolerability, and pharmacokinetic and pharmacodynamic parameters.

AbCellera’s Phase 1 Study of ABCL575: A Potential Game-Changer?
Oct 27, 2025

AbCellera Biologics Inc. is conducting a first-in-human Phase 1 study titled ‘A First-in-Human Phase 1 Single-Ascending Dose Study of ABCL575 in Healthy Participants.’ The study aims to evaluate the safety and tolerability of ABCL575, a new biological treatment, in healthy individuals through a single ascending dose approach compared to a placebo. This research is significant as it marks the initial step in assessing ABCL575’s potential therapeutic benefits.

Executive/Board Changes
AbCellera Biologics Appoints New Chief Medical Officer
Positive
Sep 10, 2025

On September 10, 2025, AbCellera Biologics announced the appointment of Dr. Sarah Noonberg as its Chief Medical Officer. Dr. Noonberg brings over two decades of experience in clinical development and will play a crucial role in advancing AbCellera’s pipeline of antibody-based therapeutics as the company transitions to a clinical-stage entity. Her previous roles include Chief Medical Officer at Metagenomi and contributions to the development of enzalutamide for prostate cancer at Medivation.

The most recent analyst rating on (ABCL) stock is a Hold with a $4.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

AbCellera Biologics Earnings Call: Clinical Progress and Financial Insights
Aug 13, 2025

AbCellera Biologics, Inc. recently held its earnings call, revealing a mix of optimism and caution. The company showcased significant advancements in clinical trials and a robust financial standing, marked by increased revenue and pipeline development. However, the call also acknowledged a net loss and an expected decline in research fee revenue, painting a complex picture of the company’s current state.

AbCellera Biologics Advances Clinical Trials and Revenue Growth
Aug 8, 2025

AbCellera Biologics Inc. is a clinical-stage biotechnology company specializing in the discovery and development of antibody-based medicines across various sectors, including endocrinology, women’s health, immunology, and oncology.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 08, 2025