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AbCellera Biologics (ABCL)
NASDAQ:ABCL

AbCellera Biologics (ABCL) AI Stock Analysis

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AbCellera Biologics

(NASDAQ:ABCL)

Rating:56Neutral
Price Target:
$3.00
▼(-6.25%Downside)
AbCellera Biologics' stock score is primarily influenced by its financial challenges, including declining revenue and profitability. However, strong technical indicators and strategic advancements in drug development provide some optimism. The company's robust liquidity position supports ongoing and future initiatives, but valuation concerns persist due to negative earnings and no dividend yield.
Positive Factors
Financial Position
The stock continues to trade near its total liquidity, implying upside from ABCL's royalty portfolio and internal pipeline.
Research and Development
AbCellera is focusing on its two leading internal R&D programs, ABCL635 in the metabolic and endocrinology medical area and ABCL575, targeting immunology and inflammation.
Strategic Partnerships
AbCellera succeeded in signing two new partnerships in 2024, with Biogen and venture firms Viking and ArrowMark, and expanding two legacy programs.
Negative Factors
Competitive Market
Leading NK3R competitors, including Astellas' Veozah and Bayer's elinzanetant, have a head start on ABCL-635.
Financial Performance
Revenues came in below estimates.
Revenue Decline
AbCellera's 4Q24 revenue of $5.0M fell below expectations as ABCL continues to wind down partner program activity.

AbCellera Biologics (ABCL) vs. SPDR S&P 500 ETF (SPY)

AbCellera Biologics Business Overview & Revenue Model

Company DescriptionAbCellera Biologics Inc. is a biotechnology company specializing in the discovery and development of therapeutic antibodies. Operating within the biopharmaceutical sector, the company leverages its advanced proprietary technology platforms to rapidly identify and develop antibody therapies. AbCellera partners with pharmaceutical companies to enhance the drug discovery process, focusing on accelerating the path from target to lead candidate.
How the Company Makes MoneyAbCellera makes money primarily through collaborations and partnerships with pharmaceutical and biotechnology companies. The company generates revenue by providing its technology and expertise to discover antibodies for its partners, who may pay upfront fees, milestone payments, and royalties on any products that result from these collaborations. AbCellera's revenue model is heavily reliant on its ability to form strategic partnerships and successfully deliver therapeutic candidates that can advance into clinical development and commercialization, thus ensuring a share in the financial success of these therapies.

AbCellera Biologics Key Performance Indicators (KPIs)

Any
Any
Number of Discovery Partners
Number of Discovery Partners
Indicates the breadth of AbCellera's collaborative network, highlighting potential for diverse innovation and revenue streams through partnerships.
Chart InsightsAbCellera's number of discovery partners has grown steadily, reaching 46 by the end of 2023. However, the latest earnings call reveals a strategic shift with reduced new partnership activities, focusing instead on advancing clinical programs like ABCL635 and ABCL575. This pivot to a clinical stage biotech, despite declining revenue and increased R&D expenses, suggests a long-term strategy prioritizing high-value partnerships and clinical advancements over sheer volume of discovery collaborations.
Data provided by:Main Street Data

AbCellera Biologics Earnings Call Summary

Earnings Call Date:May 08, 2025
(Q1-2025)
|
% Change Since: 59.20%|
Next Earnings Date:Aug 12, 2025
Earnings Call Sentiment Neutral
The earnings call highlighted significant progress in advancing key drug candidates, particularly ABCL635 and ABCL575, alongside a strong liquidity position to support ongoing and future programs. However, the call also noted a decline in revenue and increased net loss, with some development programs paused. The sentiment reflects a balance between ongoing challenges and strategic advancements.
Q1-2025 Updates
Positive Updates
Introduction of ABCL635
ABCL635 is a potential first-in-class therapeutic antibody for non-hormonal treatment of moderate-to-severe vasomotor symptoms associated with menopause. This represents a significant market opportunity with a potential for over $2 billion in annual sales.
Strong Liquidity Position
AbCellera continues to be in a strong liquidity position with approximately $630 million in cash and equivalents and roughly $180 million in available committed government funding.
Advancement of ABCL575
ABCL575 is on track with CTA filing in Q2 and anticipated start of Phase 1 clinical trials in Q3. Preclinical data will be presented at the Society for Investigative Dermatology's Annual Meeting.
Platform and Pipeline Development
AbCellera is transitioning from a platform company to a clinical-stage biotech with a portfolio of more than 20 internal and co-development programs. Investments in clinical manufacturing capabilities are nearing completion.
Negative Updates
Revenue Decline
Revenue for Q1 2025 was about $4 million, compared to $10 million in the same quarter of 2024. This decline is attributed to a focus on internal and co-development programs and a decrease in research fee revenue.
Net Loss Increase
AbCellera reported a net loss of approximately $46 million for the quarter, compared to a loss of around $41 million in the same quarter last year.
Paused Development Programs
The development of the four Trianni-license molecules that NovaRock advanced into Phase 1 are currently paused, potentially affecting near- and mid-term revenue from milestones and royalties.
Company Guidance
During the first quarter of 2025, AbCellera focused on advancing their key priorities, including initiating Phase 1 clinical trials for ABCL635 and ABCL575, which are set to start in Q3 of 2025, with key readouts expected by mid-2026. ABCL635, a first-in-class therapeutic antibody targeting the neurokinin 3 receptor (NK3R) for non-hormonal treatment of vasomotor symptoms associated with menopause, represents a significant market opportunity, valued at over $2 billion annually. Approximately 30% of women experience these symptoms, with more than half seeking treatment. AbCellera aims to differentiate ABCL635 with a monthly injectable format preferred by over 50% of surveyed women, compared to daily oral treatments. Financially, the company maintained a strong liquidity position with $630 million in cash and equivalents and $180 million in committed government funding, despite a net loss of $46 million for the quarter, driven by R&D expenses of $43 million. The company's ongoing investments focus on internal programs and completing clinical manufacturing capabilities, which are set to come online by the end of 2025.

AbCellera Biologics Financial Statement Overview

Summary
AbCellera Biologics faces significant financial challenges with drastic declines in revenue, negative profit margins, and cash flow issues. However, the company's balance sheet remains relatively strong, with low leverage and adequate liquidity.
Income Statement
25
Negative
AbCellera Biologics shows significant financial deterioration in its income statement. The company experienced a drastic decline in total revenue over the recent periods, from $485.42 million in 2022 to $23.12 million in the TTM. This resulted in negative gross profit margins and substantial net losses, reflected in a negative net profit margin. The negative EBIT and EBITDA margins further emphasize operational challenges, indicating a steep drop in operating efficiency and profitability.
Balance Sheet
60
Neutral
Despite the operational challenges, the balance sheet of AbCellera Biologics remains relatively strong, with a solid equity base. The debt-to-equity ratio is low, indicating prudent leverage management. The equity ratio remains robust, suggesting financial stability in terms of asset financing. However, there is a decline in total assets and stockholders' equity, which requires monitoring.
Cash Flow
30
Negative
Cash flow analysis reveals significant strain, with negative operating and free cash flow in the TTM. The free cash flow to net income ratio is negative, highlighting cash flow challenges relative to net losses. The operating cash flow to net income ratio is also negative, indicating issues in converting income to cash. Despite these challenges, the company maintains a healthy cash reserve.
Breakdown
TTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
23.11M28.83M38.02M485.42M375.20M233.16M
Gross Profit
-109.61M-68.17M7.13M418.99M329.69M206.01M
EBIT
-365.03M-314.77M-237.21M216.51M204.41M156.03M
EBITDA
-203.72M-204.15M-192.16M272.20M241.62M169.62M
Net Income Common Stockholders
-167.87M-162.86M-146.40M158.52M153.46M118.92M
Balance SheetCash, Cash Equivalents and Short-Term Investments
605.27M625.61M760.59M886.49M722.98M594.12M
Total Assets
579.23M1.36B1.49B1.54B1.32B1.01B
Total Debt
63.21M65.36M77.38M82.26M36.41M6.10M
Net Debt
-96.06M-90.96M-55.94M-304.28M-439.73M-588.01M
Total Liabilities
245.83M304.47M335.78M307.63M292.84M175.03M
Stockholders Equity
1.02B1.06B1.15B1.23B1.03B830.51M
Cash FlowFree Cash Flow
-142.47M-186.95M-121.38M204.70M186.13M8.02M
Operating Cash Flow
-77.89M-108.56M-43.88M277.36M244.58M22.69M
Investing Cash Flow
99.43M121.41M-221.11M-352.63M-332.25M-119.78M
Financing Cash Flow
15.87M12.77M10.36M-1.63M-3.89M683.65M

AbCellera Biologics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price3.20
Price Trends
50DMA
2.31
Positive
100DMA
2.55
Positive
200DMA
2.66
Positive
Market Momentum
MACD
0.23
Negative
RSI
78.86
Negative
STOCH
75.51
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ABCL, the sentiment is Positive. The current price of 3.2 is above the 20-day moving average (MA) of 2.35, above the 50-day MA of 2.31, and above the 200-day MA of 2.66, indicating a bullish trend. The MACD of 0.23 indicates Negative momentum. The RSI at 78.86 is Negative, neither overbought nor oversold. The STOCH value of 75.51 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for ABCL.

AbCellera Biologics Risk Analysis

AbCellera Biologics disclosed 102 risk factors in its most recent earnings report. AbCellera Biologics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

AbCellera Biologics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (54)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
78
Outperform
$916.38M6.1734.46%799.36%
60
Neutral
$701.48M222.83%29.88%35.11%
56
Neutral
$964.11M-15.59%-35.41%-12.26%
54
Neutral
$728.91M166.8111.62%
54
Neutral
$917.22M-63.56%270.02%32.69%
54
Neutral
$5.41B3.27-45.10%3.29%16.81%0.02%
42
Neutral
$929.11M-51.85%0.71%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ABCL
AbCellera Biologics
3.20
0.14
4.58%
GYRE
Gyre Therapeutics
7.99
-3.54
-30.70%
XERS
Xeris Pharmaceuticals
4.35
2.17
99.54%
CVAC
CureVac
5.57
2.09
60.06%
PRAX
Praxis Precision Medicines
44.30
7.75
21.20%
PHVS
Pharvaris
16.70
-1.96
-10.50%

AbCellera Biologics Corporate Events

Executive/Board ChangesShareholder Meetings
AbCellera Biologics Holds Annual Shareholder Meeting
Neutral
Jun 13, 2025

On June 12, 2025, AbCellera Biologics Inc. held its Annual Meeting of Shareholders, where key decisions were made regarding the election of directors, appointment of an accounting firm, and executive compensation. Shareholders approved the election of Carl L. G. Hansen and Michael Hayden as Class II directors, ratified KPMG LLP as the independent accounting firm, and endorsed executive compensation, reflecting continued support for the company’s strategic direction.

The most recent analyst rating on (ABCL) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

Product-Related AnnouncementsBusiness Operations and Strategy
AbCellera Biologics Receives Health Canada Approval for Trial
Positive
May 30, 2025

On May 30, 2025, AbCellera Biologics announced it received a No Objection Letter from Health Canada, authorizing its Clinical Trial Application for ABCL575, an investigational antibody antagonist targeting the OX40 ligand for treating moderate-to-severe atopic dermatitis. The Phase 1 clinical trial is expected to commence in Q3 2025, focusing on evaluating the safety and pharmacokinetics of ABCL575 in healthy participants. This development signifies a step forward in AbCellera’s efforts to address inflammatory and autoimmune conditions, potentially enhancing its market position and offering new treatment options for stakeholders.

The most recent analyst rating on (ABCL) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

Product-Related AnnouncementsBusiness Operations and StrategyRegulatory Filings and Compliance
AbCellera Biologics Receives Health Canada Approval for Trial
Positive
May 14, 2025

On May 14, 2025, AbCellera Biologics announced it received a No Objection Letter from Health Canada for its Clinical Trial Application for ABCL635, a novel antibody antagonist targeting the neurokinin 3 receptor for treating vasomotor symptoms associated with menopause. The Phase 1 clinical trial, expected to start in Q3 2025, will assess the safety and pharmacokinetics of ABCL635, marking a significant step in AbCellera’s efforts to offer a non-hormonal treatment for menopause-related hot flashes, potentially impacting the well-being of millions of women.

The most recent analyst rating on (ABCL) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

Legal Proceedings
AbCellera Wins Patent Appeal Against Bruker
Positive
May 13, 2025

On May 12, 2025, AbCellera Biologics announced that the United States Court of Appeals for the Federal Circuit affirmed the validity of its U.S. Patent No. 10,087,408, which pertains to microfluidic devices used for culturing and selectively recovering cells. This decision follows a challenge by Bruker Cellular Analysis, Inc., which was rejected by the U.S. Patent Trial and Appeal Board and now confirmed by the Federal Circuit. This ruling strengthens AbCellera’s intellectual property portfolio and supports its ongoing patent infringement litigation against Bruker in the U.S. District Court for the Northern District of California.

The most recent analyst rating on (ABCL) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

Product-Related AnnouncementsBusiness Operations and StrategyFinancial Disclosures
AbCellera Reports Q1 2025 Financial Results and New Antibody
Neutral
May 8, 2025

On May 8, 2025, AbCellera Biologics announced its financial results for the first quarter of 2025, reporting a total revenue of $4.2 million and a net loss of $45.6 million. The company highlighted the introduction of ABCL635, a potential first-in-class antibody for treating menopause-related vasomotor symptoms, with plans to start Phase 1 clinical trials in the latter half of 2025. Despite the financial loss, AbCellera maintained significant liquidity of over $800 million to support its strategic initiatives, including 97 partner-initiated programs and 16 molecules reaching the clinic.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.