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AbCellera Biologics (ABCL)
NASDAQ:ABCL

AbCellera Biologics (ABCL) AI Stock Analysis

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ABCL

AbCellera Biologics

(NASDAQ:ABCL)

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Neutral 49 (OpenAI - 4o)
Rating:49Neutral
Price Target:
$3.50
▼(-22.57% Downside)
AbCellera Biologics' overall stock score reflects significant financial challenges, with declining revenues and profitability issues being the most impactful factors. While technical indicators suggest potential for a rebound, the valuation remains unattractive due to ongoing losses. The earnings call and corporate events provide some positive outlook, particularly with strong liquidity and strategic partnerships, but near-term financial pressures remain a concern.
Positive Factors
Strong Liquidity Position
A strong liquidity position with $680 million available provides financial flexibility to invest in R&D and strategic initiatives, supporting long-term growth.
Strategic Partnerships
The agreement with Bruker Corporation provides $36 million upfront and future royalties, enhancing cash flow and securing ongoing revenue streams.
Transition to Clinical-Stage Biotech
Transitioning to a clinical-stage biotech with active trials indicates progress in product development, potentially leading to future revenue from successful therapies.
Negative Factors
Increased Net Loss
The increased net loss reflects ongoing financial challenges, which could strain resources and impact the company's ability to invest in growth initiatives.
Rising R&D Expenses
Rising R&D expenses, while necessary for growth, can pressure margins and profitability, requiring careful management to ensure sustainable financial health.
Stagnation in Partner-Initiated Programs
Stagnation in partner-initiated programs could limit future revenue growth, as success depends on advancing these collaborations to marketable products.

AbCellera Biologics (ABCL) vs. SPDR S&P 500 ETF (SPY)

AbCellera Biologics Business Overview & Revenue Model

Company DescriptionAbCellera Biologics Inc. develops antibody discovery platform. Its full-stack, artificial intelligence-powered antibody discovery platform searches and analyzes the database of natural immune systems to find antibodies that could be developed as drugs. As of December 31, 2021, the company had 156 discovery programs that are either completed, in progress, or under contract with 36 partners. AbCellera Biologics Inc. has a research collaboration and license agreement with Eli Lilly and Company. The company was incorporated in 2012 and is headquartered in Vancouver, Canada.
How the Company Makes MoneyAbCellera generates revenue primarily through its partnerships and collaborations with pharmaceutical companies, where it provides its antibody discovery services. The company typically enters into agreements that include upfront payments, research funding, and milestone payments based on the progress of drug development. Additionally, AbCellera may receive royalties on sales of products that result from these collaborations. The company's revenue model is heavily reliant on the successful advancement of its partners' therapeutic candidates, along with ongoing research contracts and collaborations that can provide continuous income streams.

AbCellera Biologics Key Performance Indicators (KPIs)

Any
Any
Number of Discovery Partners
Number of Discovery Partners
Indicates the breadth of AbCellera's collaborative network, highlighting potential for diverse innovation and revenue streams through partnerships.
Chart InsightsAbCellera's number of discovery partners has grown steadily, reaching 46 by the end of 2023. However, the latest earnings call reveals a strategic shift with reduced new partnership activities, focusing instead on advancing clinical programs like ABCL635 and ABCL575. This pivot to a clinical stage biotech, despite declining revenue and increased R&D expenses, suggests a long-term strategy prioritizing high-value partnerships and clinical advancements over sheer volume of discovery collaborations.
Data provided by:The Fly

AbCellera Biologics Earnings Call Summary

Earnings Call Date:Nov 06, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Feb 24, 2026
Earnings Call Sentiment Neutral
The earnings call highlights AbCellera's successful transition to a clinical-stage biotech and strong liquidity position, but also notes increased net loss and R&D expenses. While revenue has increased, the stagnation in partner-initiated programs presents a challenge.
Q3-2025 Updates
Positive Updates
Transition to Clinical-Stage Biotech
AbCellera completed its transition from a platform company to a clinical-stage biotech with the initiation of Phase I clinical trials for ABCL635 and ABCL575, both of which are progressing as planned.
Strong Liquidity Position
AbCellera ended the quarter with approximately $680 million in available liquidity, including $520 million in cash and cash equivalents and $160 million in available committed government funding.
New Clinical Manufacturing Facility
Activities have started at AbCellera's new clinical manufacturing facility, and platform investments are substantially complete.
Appointment of New Chief Medical Officer
Dr. Sarah Noonberg, a physician-scientist with over 20 years of clinical drug development experience, was appointed as the new Chief Medical Officer.
Increase in Revenue
Revenue for the quarter was $9 million, up from $7 million in the same quarter of last year, predominantly from research fees relating to work on partnered programs.
Negative Updates
Increased Net Loss
AbCellera reported a net loss of approximately $57 million for the quarter, compared to a loss of about $51 million in the same quarter of last year.
Rise in Research and Development Expenses
Research and development expenses for the quarter were $55 million, approximately $14 million more than last year, reflecting a focus on investment in internal and co-development programs.
Stagnation in Partner-Initiated Programs
The number of partner-initiated programs in the clinic has remained somewhat stagnant since 2024, with a cumulative total of 103 programs initiated.
Company Guidance
During AbCellera's Third Quarter 2025 Business Update Conference Call, several key metrics and guidance were provided. The company reported $680 million in available liquidity, including $520 million in cash and cash equivalents and $160 million in committed government funding. Revenue for the quarter was $9 million, primarily from research fees, compared to $7 million in the same quarter last year. Research and development expenses increased to $55 million, with specific investments of $15 million in two internal programs. General and administrative expenses were $22 million, and the net loss for the quarter was $57 million, translating to a loss of $0.19 per share. The company has 103 partner-initiated programs with downstream participation, and 18 molecules have reached the clinic. AbCellera aims to advance at least one more development candidate into IND-enabling studies by year-end. The appointment of Dr. Sarah Noonberg as Chief Medical Officer was highlighted as a significant development, and the company remains focused on advancing its lead programs, ABCL635 and ABCL575, through Phase I trials.

AbCellera Biologics Financial Statement Overview

Summary
AbCellera Biologics faces significant financial challenges, with declining revenues and profitability issues impacting its income statement. The balance sheet remains strong with low leverage, but cash flow struggles highlight operational inefficiencies. The company needs to focus on improving revenue stability and profitability to enhance its financial health.
Income Statement
AbCellera Biologics has experienced significant revenue volatility, with a notable decline in revenue from 2022 to 2025. The company is currently operating at a loss, with negative net profit and EBIT margins, indicating profitability challenges. However, there was a slight revenue growth in the TTM period, suggesting potential recovery.
Balance Sheet
The balance sheet shows a relatively low debt-to-equity ratio, indicating conservative leverage. However, the negative return on equity in recent periods highlights profitability issues. The equity ratio remains stable, suggesting a strong capital structure despite operational losses.
Cash Flow
Cash flow analysis reveals negative operating and free cash flows, reflecting cash management challenges. Despite this, the free cash flow to net income ratio is positive, indicating some efficiency in converting earnings to cash. The recent growth in free cash flow is a positive sign, but overall cash flow health remains weak.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue35.32M28.83M38.02M485.42M375.20M233.16M
Gross Profit28.27M28.83M38.02M418.99M329.69M206.01M
EBITDA-186.27M-204.15M-192.16M260.17M239.15M169.62M
Net Income-171.68M-162.86M-146.40M158.52M153.46M118.92M
Balance Sheet
Total Assets1.36B1.36B1.49B1.54B1.32B1.01B
Cash, Cash Equivalents and Short-Term Investments520.67M625.61M760.59M886.49M722.98M594.12M
Total Debt137.05M65.36M77.38M82.26M40.06M6.78M
Total Liabilities391.95M304.47M335.78M307.63M292.84M175.03M
Stockholders Equity964.04M1.06B1.15B1.23B1.03B830.51M
Cash Flow
Free Cash Flow-153.11M-186.95M-121.38M204.70M186.13M8.02M
Operating Cash Flow-104.55M-108.56M-43.88M277.36M244.58M22.69M
Investing Cash Flow48.31M121.41M-221.11M-352.63M-332.25M-119.78M
Financing Cash Flow14.11M12.77M10.36M-1.63M-3.89M683.65M

AbCellera Biologics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price4.52
Price Trends
50DMA
3.85
Positive
100DMA
4.43
Positive
200DMA
3.78
Positive
Market Momentum
MACD
0.11
Negative
RSI
71.59
Negative
STOCH
89.11
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ABCL, the sentiment is Positive. The current price of 4.52 is above the 20-day moving average (MA) of 3.70, above the 50-day MA of 3.85, and above the 200-day MA of 3.78, indicating a bullish trend. The MACD of 0.11 indicates Negative momentum. The RSI at 71.59 is Negative, neither overbought nor oversold. The STOCH value of 89.11 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for ABCL.

AbCellera Biologics Risk Analysis

AbCellera Biologics disclosed 102 risk factors in its most recent earnings report. AbCellera Biologics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

AbCellera Biologics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
65
Neutral
$4.16B-18.99-25.31%-64.91%
61
Neutral
$1.64B-11.20-28.57%-42.64%-39.78%
55
Neutral
$1.83B-5.73-129.32%597.19%0.45%
55
Neutral
$2.60B-6.21-68.13%-8.75%-8.79%
55
Neutral
$2.64B-15.30-30.02%-5.73%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$1.31B-7.84-16.81%7.16%3.95%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ABCL
AbCellera Biologics
4.52
1.75
63.18%
SNDX
Syndax Pharmaceuticals
20.72
8.12
64.44%
RCUS
Arcus Biosciences
21.30
7.48
54.12%
DNTH
Dianthus Therapeutics
39.12
19.24
96.78%
EWTX
Edgewise Therapeutics
24.13
-3.39
-12.32%
GPCR
Structure Therapeutics, Inc. Sponsored ADR
69.36
43.98
173.29%

AbCellera Biologics Corporate Events

Business Operations and StrategyLegal Proceedings
AbCellera Secures Global Settlement and Patent License Deal
Positive
Dec 18, 2025

On December 18, 2025, AbCellera Biologics announced a global settlement and patent license agreement with Bruker Corporation that resolves all patent litigation between the two companies. Under the agreement, Bruker will pay AbCellera $36 million upfront and provide ongoing royalty payments on worldwide sales of Bruker’s Beacon Optofluidic platform products for the life of the licensed patents, strengthening AbCellera’s cash position and securing a continuing revenue stream tied to Bruker’s commercial success.

The most recent analyst rating on (ABCL) stock is a Hold with a $3.50 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

Executive/Board Changes
AbCellera Appoints Dr. Stephen Quake to Board
Neutral
Nov 12, 2025

On November 10, 2025, AbCellera Biologics announced the appointment of Dr. Stephen Quake to its Board of Directors, enhancing the company’s commitment to scientific excellence. Dr. Quake, a renowned scientist and entrepreneur, brings extensive expertise in fields such as genomics and molecular diagnostics, aligning with AbCellera’s strategic goals. Concurrently, Andrew Lo resigned from the board, having contributed significantly to the company’s business and strategy since 2021.

The most recent analyst rating on (ABCL) stock is a Hold with a $4.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

Business Operations and StrategyExecutive/Board ChangesFinancial Disclosures
AbCellera Biologics Reports Q3 2025 Financial Results
Neutral
Nov 6, 2025

AbCellera Biologics reported its financial results for the third quarter of 2025, highlighting the start of activities at its new clinical manufacturing facility and substantial completion of platform investments. The company ended the quarter with $680 million in available liquidity, despite a net loss of $57.1 million. Key developments included the appointment of a new Chief Medical Officer and progress in Phase 1 clinical trials for its lead programs. The company also reported an increase in partner-initiated program starts and molecules advanced into the clinic, reflecting its strategic focus on expanding its pipeline.

The most recent analyst rating on (ABCL) stock is a Hold with a $5.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 19, 2025