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AbCellera Biologics (ABCL)
NASDAQ:ABCL
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AbCellera Biologics (ABCL) AI Stock Analysis

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ABCL

AbCellera Biologics

(NASDAQ:ABCL)

Rating:57Neutral
Price Target:
$4.50
▼(-1.96% Downside)
AbCellera Biologics' overall stock score reflects significant financial challenges, offset by positive technical indicators and strategic advancements in clinical trials. The strong liquidity position and recent revenue increases from licensing fees are positives, but ongoing net losses and cash flow issues pose risks.
Positive Factors
Financial Performance
AbCellera Biologics reported a significant increase in revenues for the second quarter, reaching $17.1 million compared to $7.3 million in the prior year period, supported by a Trianni-license backed milestone payment.
Market Opportunities
ABCL575 and ABCL635 are set to enter Phase 1 trials, targeting large commercial opportunities with promising data expected in the future.
Pipeline Development
AbCellera's initiation of dosing for its clinical asset, ABCL-575, for moderate-to-severe vasomotor symptoms marks an important milestone in its transition towards a biotech identity.
Negative Factors
Analyst Rating
Analyst is maintaining a Hold rating on ABCL shares as the Company decreases its revenue-generating development partnership activities and focuses more on its internal pipeline development.
Clinical Risk
There is a clinical risk for targeting NK3R with ABCL635 due to concerns about sufficient target engagement and potential safety issues related to liver toxicity.
Revenue Generation
The Company is decreasing its revenue-generating development partnership activities and focusing more on its internal pipeline development.

AbCellera Biologics (ABCL) vs. SPDR S&P 500 ETF (SPY)

AbCellera Biologics Business Overview & Revenue Model

Company DescriptionAbCellera Biologics Inc. is a biotechnology company specializing in the discovery and development of therapeutic antibodies. Operating within the biopharmaceutical sector, the company leverages its advanced proprietary technology platforms to rapidly identify and develop antibody therapies. AbCellera partners with pharmaceutical companies to enhance the drug discovery process, focusing on accelerating the path from target to lead candidate.
How the Company Makes MoneyAbCellera makes money primarily through collaborations and partnerships with pharmaceutical and biotechnology companies. The company generates revenue by providing its technology and expertise to discover antibodies for its partners, who may pay upfront fees, milestone payments, and royalties on any products that result from these collaborations. AbCellera's revenue model is heavily reliant on its ability to form strategic partnerships and successfully deliver therapeutic candidates that can advance into clinical development and commercialization, thus ensuring a share in the financial success of these therapies.

AbCellera Biologics Key Performance Indicators (KPIs)

Any
Any
Number of Discovery Partners
Number of Discovery Partners
Indicates the breadth of AbCellera's collaborative network, highlighting potential for diverse innovation and revenue streams through partnerships.
Chart InsightsAbCellera's number of discovery partners has grown steadily, reaching 46 by the end of 2023. However, the latest earnings call reveals a strategic shift with reduced new partnership activities, focusing instead on advancing clinical programs like ABCL635 and ABCL575. This pivot to a clinical stage biotech, despite declining revenue and increased R&D expenses, suggests a long-term strategy prioritizing high-value partnerships and clinical advancements over sheer volume of discovery collaborations.
Data provided by:Main Street Data

AbCellera Biologics Earnings Call Summary

Earnings Call Date:Aug 07, 2025
(Q2-2025)
|
% Change Since: 8.25%|
Next Earnings Date:Nov 11, 2025
Earnings Call Sentiment Positive
The earnings call highlighted significant advancements in clinical trials and a strong financial position, with increased revenue and pipeline development. However, it also included a reported net loss and anticipated decline in research fee revenue.
Q2-2025 Updates
Positive Updates
Health Canada Authorization for Clinical Trials
AbCellera achieved a major milestone by receiving Health Canada authorization to initiate the first two clinical trials for ABCL635 and ABCL575.
Dosing Initiated in Phase I Clinical Trial
Dosing has begun in the Phase I clinical trial evaluating ABCL635 for moderate to severe vasomotor symptoms.
Strong Financial Position
AbCellera ended the quarter with approximately $750 million in available liquidity, well-positioned to execute on strategy.
Revenue Increase
Revenue for the quarter was approximately $17 million, up from $7 million in the same quarter of 2024.
Advancement of ABCL688
ABCL688 was advanced into IND-enabling studies, marking the addition of a third program to the pipeline.
Negative Updates
Net Loss Reported
AbCellera reported a net loss of roughly $35 million for the quarter, compared to a loss of $37 million in the same quarter last year.
Decreased Research Fee Revenue
Research fee revenue is expected to trend lower as focus shifts to internal and co-development programs.
Continued Expenses in Defense of Intellectual Property
General and administration expenses include ongoing expenses related to the defense of intellectual property.
Company Guidance
During AbCellera's Second Quarter 2025 Business Update Conference Call, the company provided comprehensive guidance on its recent achievements and future plans. The call highlighted the initiation of two Phase I clinical trials for ABCL635 and ABCL575, marking a significant transition to a clinical-stage biotech. AbCellera ended the quarter with $750 million in available liquidity, aiming to advance at least one more development candidate into IND-enabling studies by the end of 2025. The company reported a net loss of $35 million for the quarter, with revenue reaching $17 million, a significant increase from $7 million in the same quarter of 2024. The revenue included $10 million from the licensing fees of their Trianni humanized rodent platform. AbCellera's leadership expressed confidence in their financial position, emphasizing their capacity to fund operations beyond the next three years. The company also plans to complete investments in platform and infrastructure to support clinical manufacturing capabilities by year's end.

AbCellera Biologics Financial Statement Overview

Summary
AbCellera Biologics faces significant financial challenges, with a drastic revenue decline leading to negative margins and operational inefficiencies. The balance sheet remains relatively strong, providing some stability, but cash flow issues are a concern.
Income Statement
25
Negative
AbCellera Biologics shows significant financial deterioration in its income statement. The company experienced a drastic decline in total revenue over the recent periods, from $485.42 million in 2022 to $23.12 million in the TTM. This resulted in negative gross profit margins and substantial net losses, reflected in a negative net profit margin. The negative EBIT and EBITDA margins further emphasize operational challenges, indicating a steep drop in operating efficiency and profitability.
Balance Sheet
60
Neutral
Despite the operational challenges, the balance sheet of AbCellera Biologics remains relatively strong, with a solid equity base. The debt-to-equity ratio is low, indicating prudent leverage management. The equity ratio remains robust, suggesting financial stability in terms of asset financing. However, there is a decline in total assets and stockholders' equity, which requires monitoring.
Cash Flow
30
Negative
Cash flow analysis reveals significant strain, with negative operating and free cash flow in the TTM. The free cash flow to net income ratio is negative, highlighting cash flow challenges relative to net losses. The operating cash flow to net income ratio is also negative, indicating issues in converting income to cash. Despite these challenges, the company maintains a healthy cash reserve.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue28.83M38.02M485.42M375.20M233.16M
Gross Profit-68.17M7.13M418.99M329.69M206.01M
EBITDA-204.15M-192.16M272.20M241.62M169.62M
Net Income-162.86M-146.40M158.52M153.46M118.92M
Balance Sheet
Total Assets1.36B1.49B1.54B1.32B1.01B
Cash, Cash Equivalents and Short-Term Investments625.61M760.59M886.49M722.98M594.12M
Total Debt65.36M77.38M82.26M40.06M6.78M
Total Liabilities304.47M335.78M307.63M292.84M175.03M
Stockholders Equity1.06B1.15B1.23B1.03B830.51M
Cash Flow
Free Cash Flow-186.95M-121.38M204.70M186.13M8.02M
Operating Cash Flow-108.56M-43.88M277.36M244.58M22.69M
Investing Cash Flow121.41M-221.11M-352.63M-332.25M-119.78M
Financing Cash Flow12.77M10.36M-1.63M-3.89M683.65M

AbCellera Biologics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price4.59
Price Trends
50DMA
3.97
Positive
100DMA
3.10
Positive
200DMA
2.99
Positive
Market Momentum
MACD
0.12
Positive
RSI
56.32
Neutral
STOCH
58.02
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ABCL, the sentiment is Positive. The current price of 4.59 is below the 20-day moving average (MA) of 4.59, above the 50-day MA of 3.97, and above the 200-day MA of 2.99, indicating a neutral trend. The MACD of 0.12 indicates Positive momentum. The RSI at 56.32 is Neutral, neither overbought nor oversold. The STOCH value of 58.02 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for ABCL.

AbCellera Biologics Risk Analysis

AbCellera Biologics disclosed 102 risk factors in its most recent earnings report. AbCellera Biologics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

AbCellera Biologics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (47)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
76
Outperform
$1.24B6.0734.46%799.36%
67
Neutral
$1.18B222.83%35.62%49.58%
59
Neutral
$791.69M504.295.47%
57
Neutral
$1.34B-15.64%-0.54%-6.28%
49
Neutral
$1.00B-60.98%338.45%-19.64%
47
Neutral
C$213.29M-1.44-30.58%3.10%19.48%-0.04%
42
Neutral
$1.47B-63.96%-36.92%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ABCL
AbCellera Biologics
4.59
1.88
69.37%
GYRE
Gyre Therapeutics
8.14
-3.62
-30.78%
XERS
Xeris Pharmaceuticals
7.68
4.96
182.35%
CVAC
CureVac
5.48
2.17
65.56%
PRAX
Praxis Precision Medicines
47.08
-4.76
-9.18%
PHVS
Pharvaris
22.30
3.60
19.25%

AbCellera Biologics Corporate Events

Business Operations and StrategyFinancial Disclosures
AbCellera Biologics Reports Q2 2025 Financial Results
Neutral
Aug 7, 2025

AbCellera Biologics reported its financial results for Q2 2025, highlighting a net loss of $34.7 million, which is an improvement from the previous year’s loss. The company also initiated dosing in a Phase 1 clinical trial for ABCL635, a potential treatment for vasomotor symptoms associated with menopause, marking its transition to a clinical-stage company. Additionally, AbCellera received authorization to begin Phase 1 trials for ABCL575 and advanced ABCL688 into IND-enabling studies, demonstrating significant progress in its pipeline. With over $750 million in available liquidity, AbCellera is well-positioned to continue executing its strategic initiatives.

The most recent analyst rating on (ABCL) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

Executive/Board ChangesShareholder Meetings
AbCellera Biologics Holds Annual Shareholder Meeting
Neutral
Jun 13, 2025

On June 12, 2025, AbCellera Biologics Inc. held its Annual Meeting of Shareholders, where key decisions were made regarding the election of directors, appointment of an accounting firm, and executive compensation. Shareholders approved the election of Carl L. G. Hansen and Michael Hayden as Class II directors, ratified KPMG LLP as the independent accounting firm, and endorsed executive compensation, reflecting continued support for the company’s strategic direction.

The most recent analyst rating on (ABCL) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

Product-Related AnnouncementsBusiness Operations and Strategy
AbCellera Biologics Receives Health Canada Approval for Trial
Positive
May 30, 2025

On May 30, 2025, AbCellera Biologics announced it received a No Objection Letter from Health Canada, authorizing its Clinical Trial Application for ABCL575, an investigational antibody antagonist targeting the OX40 ligand for treating moderate-to-severe atopic dermatitis. The Phase 1 clinical trial is expected to commence in Q3 2025, focusing on evaluating the safety and pharmacokinetics of ABCL575 in healthy participants. This development signifies a step forward in AbCellera’s efforts to address inflammatory and autoimmune conditions, potentially enhancing its market position and offering new treatment options for stakeholders.

The most recent analyst rating on (ABCL) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

Product-Related AnnouncementsBusiness Operations and StrategyRegulatory Filings and Compliance
AbCellera Biologics Receives Health Canada Approval for Trial
Positive
May 14, 2025

On May 14, 2025, AbCellera Biologics announced it received a No Objection Letter from Health Canada for its Clinical Trial Application for ABCL635, a novel antibody antagonist targeting the neurokinin 3 receptor for treating vasomotor symptoms associated with menopause. The Phase 1 clinical trial, expected to start in Q3 2025, will assess the safety and pharmacokinetics of ABCL635, marking a significant step in AbCellera’s efforts to offer a non-hormonal treatment for menopause-related hot flashes, potentially impacting the well-being of millions of women.

The most recent analyst rating on (ABCL) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

Legal Proceedings
AbCellera Wins Patent Appeal Against Bruker
Positive
May 13, 2025

On May 12, 2025, AbCellera Biologics announced that the United States Court of Appeals for the Federal Circuit affirmed the validity of its U.S. Patent No. 10,087,408, which pertains to microfluidic devices used for culturing and selectively recovering cells. This decision follows a challenge by Bruker Cellular Analysis, Inc., which was rejected by the U.S. Patent Trial and Appeal Board and now confirmed by the Federal Circuit. This ruling strengthens AbCellera’s intellectual property portfolio and supports its ongoing patent infringement litigation against Bruker in the U.S. District Court for the Northern District of California.

The most recent analyst rating on (ABCL) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 12, 2025