tiprankstipranks
Trending News
More News >
Vor Biopharma, Inc. (VOR)
NASDAQ:VOR
US Market

Vor Biopharma (VOR) AI Stock Analysis

Compare
962 Followers

Top Page

VOR

Vor Biopharma

(NASDAQ:VOR)

Select Model
Select Model
Select Model
Neutral 47 (OpenAI - 5.2)
Rating:47Neutral
Price Target:
$15.50
▼(-1.59% Downside)
Score is primarily weighed down by weak financial performance (no revenue, heavy losses, and sharply negative equity). Technicals are neutral-to-mixed with longer-term downtrends still evident, while valuation remains unattractive due to ongoing losses. Offsetting factors include positive corporate events—meaningful recent capital raises and constructive telitacicept program updates that improve runway and strategic positioning.
Positive Factors
NEJM-published Phase 3 efficacy
Publication of Phase 3 SLE data in NEJM and replicated Phase 3 signals materially de-risk telitacicept’s clinical profile. High-quality peer-reviewed data strengthens regulatory credibility, informs label strategy and payer discussions, and supports durable commercial potential across indications.
Established China commercial footprint via partner
Partner RemeGen’s existing commercialization and sizable clinical exposure provide validated safety and real‑world use data. This lowers go‑to‑market risk, enables faster regional uptake, and offers a durable pathway to revenue and licensing/royalty upside as global development progresses.
Materially extended runway from recent financings
Fresh private and public financings significantly bolster near‑term liquidity, providing funding for global Phase 3 trials, manufacturing and pre‑commercial activities. Extended runway into mid‑2028 reduces immediate financing pressure and supports execution of key clinical and regulatory milestones.
Negative Factors
No commercial revenue and large losses
Vor remains a development‑stage company with no product cash flows and a TTM net loss surge, limiting operating leverage and internal funding capacity. Persistent heavy losses increase execution risk and make long‑term sustainability contingent on successful clinical outcomes and continued external capital.
Negative stockholders' equity
A shift to materially negative equity signals balance sheet deterioration despite low nominal debt. Negative equity can constrain financial flexibility, complicate future capital raises or partnerships, and represents a structural solvency concern that persists absent meaningful earnings or asset infusions.
Sustained cash burn and financing reliance
Consistently large negative operating and free cash flows mean ongoing program funding depends on capital markets. Repeated dilutive financings can erode shareholder value and, if market access tightens, could delay trials or commercialization—an enduring execution risk for a pre‑revenue biotech.

Vor Biopharma (VOR) vs. SPDR S&P 500 ETF (SPY)

Vor Biopharma Business Overview & Revenue Model

Company DescriptionVor Biopharma, Inc., a clinical-stage company, develops engineered hematopoietic stem cell (eHSC) therapies for cancer patients. It is developing VOR33, an eHSC product candidate that is in phase 1/2 to treat acute myeloid leukemia (AML) and other hematological malignancies. The company's VOR33 eHSCs lacks CD33, a protein that is expressed by AML blood cancer cells. The company's eHSCs targeted therapies, such as CAR-Ts, bispecific antibodies, and antibody-drug conjugates provide treatment for blood cancers. Vor Biopharma, Inc. has a collaboration agreement with Akron BioProducts to develop and manufacture cGMP nucleases. The company was incorporated in 2015 and is headquartered in Cambridge, Massachusetts.
How the Company Makes MoneyVor Biopharma generates revenue primarily through research and development collaborations, partnerships, and potential future product sales. The company's business model is centered around developing its pipeline of eHSC-based therapies, which are designed to improve the efficacy and safety of existing cancer treatments. Revenue streams may include milestone payments and royalties from strategic partnerships with larger pharmaceutical companies, as well as potential licensing agreements for its proprietary technologies. Additionally, Vor Biopharma may secure funding through government grants or research institutions to support its innovative research initiatives.

Vor Biopharma Financial Statement Overview

Summary
Vor Biopharma demonstrates significant financial strain, with no revenue generation and consistent net losses. The company's balance sheet shows declining equity, and cash flow statements reflect ongoing cash burn problems. These factors collectively point to high financial risk and uncertainty about future viability.
Income Statement
8
Very Negative
Vor Biopharma has consistently reported zero revenue, indicating a lack of operational income generation. The company has been operating at a loss for several years, with negative EBIT and net income, highlighting significant profitability challenges.
Balance Sheet
12
Very Negative
The company maintains a moderate debt-to-equity ratio, which suggests limited leverage. However, the continuous decline in stockholders' equity and total assets since 2020 raises concerns about financial stability and sustainability.
Cash Flow
18
Very Negative
Vor Biopharma's free cash flow has been consistently negative, indicating cash burn issues. The operating cash flow is also negative, suggesting operational inefficiencies and an inability to cover costs without external funding.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-1.69M0.00-3.49M-8.96M0.000.00
EBITDA-1.12B-117.66M-114.37M-83.13M-67.58M-42.76M
Net Income-2.45B-116.91M-117.86M-92.09M-68.90M-43.34M
Balance Sheet
Total Assets176.24M142.89M209.83M299.37M242.59M75.91M
Cash, Cash Equivalents and Short-Term Investments170.46M91.93M137.18M230.25M207.47M48.54M
Total Debt3.06M31.83M35.66M38.91M18.01M18.29M
Total Liabilities2.40B46.23M59.10M48.76M26.33M27.64M
Stockholders Equity-2.23B96.66M150.72M250.61M216.26M48.27M
Cash Flow
Free Cash Flow-144.67M-99.89M-101.36M-93.61M-73.04M-40.45M
Operating Cash Flow-143.97M-99.66M-100.29M-85.14M-69.14M-36.29M
Investing Cash Flow100.00K96.86M71.01M-94.09M-91.65M-4.16M
Financing Cash Flow249.29M53.39M2.94M117.14M232.91M82.53M

Vor Biopharma Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price15.75
Price Trends
50DMA
11.92
Positive
100DMA
22.46
Negative
200DMA
22.23
Negative
Market Momentum
MACD
0.42
Negative
RSI
59.01
Neutral
STOCH
89.40
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For VOR, the sentiment is Neutral. The current price of 15.75 is above the 20-day moving average (MA) of 13.35, above the 50-day MA of 11.92, and below the 200-day MA of 22.23, indicating a neutral trend. The MACD of 0.42 indicates Negative momentum. The RSI at 59.01 is Neutral, neither overbought nor oversold. The STOCH value of 89.40 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for VOR.

Vor Biopharma Risk Analysis

Vor Biopharma disclosed 81 risk factors in its most recent earnings report. Vor Biopharma reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Vor Biopharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
59
Neutral
$152.12M7.0619.23%
58
Neutral
$268.76M-1.92-37.98%14.33%
56
Neutral
$498.17M-2.25-70.82%-21.22%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
$308.06M-1072.48%
47
Neutral
$145.81M-0.86-74.28%-19.00%-2.72%
42
Neutral
$160.78M-2.22-114.26%-17.87%14.42%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
VOR
Vor Biopharma
15.75
-10.85
-40.79%
CDXS
Codexis
1.67
-3.33
-66.60%
BDTX
Black Diamond Therapeutics
2.56
0.36
16.36%
AVIR
Atea Pharmaceuticals
3.40
0.03
0.89%
CRBU
Caribou Biosciences
1.46
-0.07
-4.58%
KYTX
Kyverna Therapeutics, Inc.
8.36
5.03
151.05%

Vor Biopharma Corporate Events

Business Operations and StrategyProduct-Related Announcements
Vor Biopharma to Highlight Telitacicept at JPM Conference
Positive
Jan 12, 2026

Vor Biopharma announced that it will present and host one-on-one investor meetings at the 44th Annual J.P. Morgan Healthcare Conference in San Francisco on January 13, 2026, where it is highlighting telitacicept as a leading dual BAFF/APRIL inhibitor for B cell–mediated autoimmune diseases. The company emphasized that telitacicept already has an established commercial footprint and broad clinical data package in China through partner RemeGen across several autoimmune conditions, a favorable and predictable safety profile observed in about 1,800 clinical trial participants and tens of thousands of treated patients, and robust efficacy signals in generalized myasthenia gravis, while outlining a global development plan that includes a Phase 3 trial in generalized myasthenia gravis with topline data expected in the first half of 2027 and a Phase 3 trial in Sjögren’s disease planned to start in the first half of 2026, supported by approximately $450 million in cash and investments as of December 2025, which the company says provides runway into mid-2028 to fund these key milestones.

The most recent analyst rating on (VOR) stock is a Buy with a $50.00 price target. To see the full list of analyst forecasts on Vor Biopharma stock, see the VOR Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Vor Biopharma CDO Departs, Transition Support Planned
Neutral
Jan 2, 2026

On December 31, 2025, Vor Biopharma Inc. entered into a separation agreement with its Chief Development Officer, Dr. Qing Zuraw, following her decision to pursue other opportunities, with her employment ending the same day and severance benefits provided in line with the terms of her 2025 employment agreement and subsequent amendment. The agreement includes a general release of claims, a 12‑month non‑compete, and standard non‑disparagement and confidentiality provisions, and the company expects to engage Dr. Zuraw as a consultant to support the transition during the first quarter of 2026, signaling an effort to maintain continuity in its development operations despite the leadership change.

The most recent analyst rating on (VOR) stock is a Hold with a $13.50 price target. To see the full list of analyst forecasts on Vor Biopharma stock, see the VOR Stock Forecast page.

Business Operations and StrategyExecutive/Board ChangesPrivate Placements and Financing
Vor Biopharma strengthens board following $150M private placement
Positive
Dec 18, 2025

On December 15, 2025, Vor Bio entered into a securities purchase agreement for a $150 million private placement of 13,876,032 common shares at $10.81 each to a group of institutional and accredited healthcare specialist investors, including RA Capital Management and Forbion, without using a placement agent. The company plans to use the proceeds to fund the clinical development of its lead asset telitacicept, including an ongoing global Phase 3 trial in myasthenia gravis and a planned global Phase 3 trial in primary Sjögren’s disease, and for general corporate purposes, while concurrently granting investors registration rights for resale of the shares and allowing Forbion to appoint one director to Vor Bio’s board. On December 17, 2025, board member Sarah Reed resigned without a dispute, and on December 18, 2025, Vor Bio appointed RA Capital’s Andrew Levin as an independent Class II director and Forbion’s Wouter Joustra as an independent Class III director, moves that deepen the company’s ties with major life sciences investors and bring additional venture and capital markets expertise to its board as it advances late-stage autoimmune programs.

The most recent analyst rating on (VOR) stock is a Buy with a $43.00 price target. To see the full list of analyst forecasts on Vor Biopharma stock, see the VOR Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Vor Biopharma Approves Stock Option Repricing Plan
Neutral
Dec 9, 2025

On December 5, 2025, Vor Biopharma‘s board approved a stock option repricing, reducing the exercise price of certain options to $8.18 per share to align with the market value on that date. This decision aims to retain and motivate employees by making their options more attractive without incurring additional equity or cash costs, impacting approximately 5.2 million shares. The repricing includes options held by key executives, such as CEO Jean-Paul Kress, and involves a retention period until December 5, 2027, or other specified conditions. Additionally, CFO Sandy Mahatme’s restricted stock units were replaced with an option to purchase 1,388,274 shares, with similar repricing terms.

The most recent analyst rating on (VOR) stock is a Hold with a $9.00 price target. To see the full list of analyst forecasts on Vor Biopharma stock, see the VOR Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
Vor Biopharma Announces $93.7 Million Public Offering
Positive
Nov 12, 2025

On November 10, 2025, Vor Biopharma Inc. announced an underwriting agreement for a public offering of 10 million shares of common stock at $10 per share, expected to raise approximately $93.7 million. The proceeds will be used to advance clinical development of telitacicept, including a Phase 3 trial for primary Sjögren’s Disease, and support manufacturing and pre-commercialization activities. This financial move aims to sustain the company’s operations and capital expenditures into the second quarter of 2027, potentially strengthening its position in the biotechnology sector.

The most recent analyst rating on (VOR) stock is a Buy with a $55.00 price target. To see the full list of analyst forecasts on Vor Biopharma stock, see the VOR Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Vor Biopharma Appoints New Chief Medical Officer
Neutral
Nov 3, 2025

On November 2, 2025, Vor Biopharma Inc. amended the employment agreement with its Chief Development Officer, Dr. Qing Zuraw, to include additional severance benefits in case of termination without cause or resignation after December 31, 2025. On November 3, 2025, Vor Bio announced the appointment of Dr. Jeremy Sokolove as Chief Medical Officer, bringing extensive experience in rheumatology and autoimmune disease research to the company, which aims to advance its clinical strategy and enhance patient outcomes.

The most recent analyst rating on (VOR) stock is a Buy with a $55.00 price target. To see the full list of analyst forecasts on Vor Biopharma stock, see the VOR Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Vor Biopharma Unveils Promising Phase 3 Trial Results
Positive
Oct 28, 2025

On October 28, 2025, Vor Biopharma Inc. hosted a webcast to present 48-week Phase 3 clinical trial data from China for telitacicept in treating primary Sjögren’s disease. The results indicated significant improvements in disease symptoms and control, with nearly 90% of patients reporting positive outcomes. This development positions telitacicept as a potentially transformative therapy in the autoimmune disease space, enhancing Vor Biopharma’s competitive edge and offering promising implications for stakeholders in terms of market opportunities and patient treatment options.

The most recent analyst rating on (VOR) stock is a Buy with a $64.00 price target. To see the full list of analyst forecasts on Vor Biopharma stock, see the VOR Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 13, 2026