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Veracyte Inc (VCYT)
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Veracyte (VCYT) AI Stock Analysis

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VCYT

Veracyte

(NASDAQ:VCYT)

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Outperform 76 (OpenAI - 4o)
Rating:76Outperform
Price Target:
$53.00
▲(46.73% Upside)
Veracyte's strong financial performance and positive earnings call are the most significant factors driving the score. The company shows robust revenue growth and profitability, supported by strategic initiatives. However, the high P/E ratio suggests potential overvaluation, and technical indicators show strong momentum but caution due to overbought signals.
Positive Factors
Revenue Growth
Consistent revenue growth indicates strong market demand and effective sales strategies, supporting long-term business expansion.
Profitability Improvement
Improved profitability through higher EBITDA margins enhances financial resilience and supports reinvestment in growth initiatives.
Low Leverage
Low leverage reduces financial risk and increases flexibility for strategic investments and operational stability.
Negative Factors
Cash Flow Management
Decreasing free cash flow may limit the company's ability to fund new projects and manage operational expenses effectively.
Biopharmaceutical Revenue Decline
Declining biopharmaceutical revenue could impact overall revenue diversification and growth potential in this segment.
Competitive Pressures
Emerging technologies pose competitive threats, requiring continuous innovation and evidence generation to maintain market leadership.

Veracyte (VCYT) vs. SPDR S&P 500 ETF (SPY)

Veracyte Business Overview & Revenue Model

Company DescriptionVeracyte, Inc. (VCYT) is a genomic diagnostics company focused on improving patient outcomes through accurate and timely disease diagnosis. The company specializes in providing innovative diagnostic solutions primarily in the fields of oncology and pulmonary medicine. Veracyte's core products include its flagship Afirma genomic sequencing classifier for thyroid cancer diagnosis, as well as other tests designed to enhance the detection and management of cancer and other diseases, leveraging advanced genomic technologies.
How the Company Makes MoneyVeracyte generates revenue primarily through the sale of its diagnostic tests to healthcare providers, which include hospitals, clinics, and laboratories. The company charges fees for each test performed, which are typically covered by insurance providers, thus facilitating access for patients. Additionally, Veracyte may engage in partnerships with pharmaceutical companies or research institutions that can contribute to revenue through collaborative research agreements or co-development of new tests. The company may also receive royalties or licensing fees from their intellectual property related to their diagnostic technologies.

Veracyte Key Performance Indicators (KPIs)

Any
Any
Revenue By Segment
Revenue By Segment
Chart Insights
Data provided by:The Fly

Veracyte Earnings Call Summary

Earnings Call Date:Nov 04, 2025
(Q3-2025)
|
Next Earnings Date:Mar 02, 2026
Earnings Call Sentiment Positive
Veracyte delivered a strong quarter with record revenue growth and profitability, driven by robust performance from its core testing business, particularly Decipher and Afirma. The company achieved a significant milestone by reaching its adjusted EBITDA margin target ahead of schedule. However, challenges remain in the form of declining biopharmaceutical revenue, competitive pressures from new technologies, and a slight decrease in testing ASP.
Q3-2025 Updates
Positive Updates
Record Revenue Growth
Veracyte reported total revenue growth of 14% year-over-year to approximately $132 million in Q3 2025. Core testing business revenue grew by 18%, with significant contributions from Decipher (26% volume growth) and Afirma (13% volume growth).
Strong Profitability
Adjusted EBITDA margin reached a record 30%, representing a 650 basis point improvement from the prior year. This performance was well ahead of expectations, with the company achieving its goal of a 25% adjusted EBITDA margin more than a year ahead of internal plans.
Decipher's Clinical Utility and Growth
Decipher delivered approximately 26,700 tests in Q3, marking the 14th consecutive quarter of over 25% year-over-year volume growth. The test is increasingly recognized by physicians for its clinical utility across all risk categories, particularly in high-risk localized and metastatic patients.
Afirma's Continued Success
Afirma achieved 13% volume growth in Q3 2025, driven by new account wins and increased utilization per account. The operational efficiency program is progressing well, with a transition to a new transcriptome workflow expected to be completed by year-end.
Positive Financial Outlook
Veracyte raised its 2025 total revenue guidance to $506 million to $510 million, up from previous guidance. The adjusted EBITDA margin guidance was also raised to exceed 25% for the year.
Negative Updates
Biopharmaceutical Revenue Decline
Biopharmaceutical and other revenue decreased to $800,000 from $3.1 million in the prior year period, attributed to the restructuring and liquidation of Veracyte SAS.
Challenging Competitive Landscape
Concerns were raised about discordant results between Decipher and digital pathology AI (DPAI) scores, potentially confusing clinicians. Despite Decipher being considered the gold standard, the emergence of new technologies requires careful evidence generation to maintain leadership.
Testing ASP Decline
Testing ASP decreased by 2% compared to the prior year, primarily due to the impact of higher prior period collections and the Afirma Laboratory Benefit Manager impact.
Company Guidance
During the Veracyte Q3 2025 financial results call, the company highlighted a robust quarter with significant metrics underscoring its performance and future guidance. Veracyte reported a 14% year-over-year increase in total revenue, amounting to approximately $132 million, driven by an 18% increase in its core testing business revenue, excluding Envisia. This was further supported by a 26% volume growth in Decipher and a 13% increase in Afirma. The company's adjusted EBITDA margin reached a record 30%, marking a 650-basis point improvement from the prior year. Veracyte raised its full-year revenue guidance to $506-510 million and increased its adjusted EBITDA margin guidance to exceed 25% for 2025. The company also emphasized its strategic growth initiatives, including the sustained expansion of Decipher, the transition to the Afirma v2 transcriptome, and the upcoming launch of its MRD platform, TrueMRD, in muscle invasive bladder cancer.

Veracyte Financial Statement Overview

Summary
Veracyte demonstrates solid financial health with consistent revenue growth and strong cash flow generation. The company maintains a conservative balance sheet with low leverage, although profitability metrics suggest there is room for improvement. Overall, Veracyte is well-positioned in the biotechnology industry with a stable financial foundation.
Income Statement
75
Positive
Veracyte has shown consistent revenue growth, with a TTM revenue growth rate of 3.34%. The gross profit margin is strong at 67.61%, indicating efficient cost management. However, the net profit margin is relatively low at 6.12%, suggesting room for improvement in profitability. The EBIT and EBITDA margins have improved over the years, reflecting better operational efficiency.
Balance Sheet
70
Positive
The company maintains a low debt-to-equity ratio of 0.03, indicating conservative leverage. Return on equity is modest at 2.21%, showing limited profitability relative to shareholder equity. The equity ratio is healthy, suggesting a strong capital structure with a significant portion of assets financed by equity.
Cash Flow
80
Positive
Veracyte's cash flow position is robust, with a significant free cash flow growth rate of 26.78% in the TTM period. The operating cash flow to net income ratio is strong at 1.50, indicating good cash generation relative to net income. The free cash flow to net income ratio is also healthy at 0.65, reflecting efficient cash management.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue495.14M445.76M361.05M296.54M219.51M117.48M
Gross Profit337.39M298.14M248.15M194.95M145.11M76.03M
EBITDA47.12M49.20M-49.41M-6.98M-60.18M-26.74M
Net Income30.32M24.14M-74.40M-36.56M-75.56M-34.91M
Balance Sheet
Total Assets1.37B1.30B1.11B1.16B1.19B457.16M
Cash, Cash Equivalents and Short-Term Investments366.43M289.44M216.45M178.85M177.16M349.36M
Total Debt40.45M50.74M12.63M14.72M18.85M12.32M
Total Liabilities110.12M124.07M70.80M81.22M91.31M35.93M
Stockholders Equity1.26B1.18B1.04B1.08B1.10B421.23M
Cash Flow
Free Cash Flow98.21M63.81M34.26M-1.01M-37.00M-12.55M
Operating Cash Flow108.25M75.10M44.22M7.54M-31.62M-9.71M
Investing Cash Flow-57.92M-56.27M15.11M-29.39M-739.21M-3.84M
Financing Cash Flow-8.58M4.90M2.84M3.49M596.32M203.59M

Veracyte Technical Analysis

Technical Analysis Sentiment
Positive
Last Price36.12
Price Trends
50DMA
39.04
Positive
100DMA
33.93
Positive
200DMA
31.82
Positive
Market Momentum
MACD
2.41
Positive
RSI
55.23
Neutral
STOCH
52.14
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For VCYT, the sentiment is Positive. The current price of 36.12 is below the 20-day moving average (MA) of 43.73, below the 50-day MA of 39.04, and above the 200-day MA of 31.82, indicating a bullish trend. The MACD of 2.41 indicates Positive momentum. The RSI at 55.23 is Neutral, neither overbought nor oversold. The STOCH value of 52.14 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for VCYT.

Veracyte Risk Analysis

Veracyte disclosed 57 risk factors in its most recent earnings report. Veracyte reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Veracyte Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
76
Outperform
$2.84B121.322.49%16.41%
60
Neutral
$3.82B-28.17%129.21%80.35%
55
Neutral
$3.13B-410.78%114.22%77.02%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
$4.00B-95.93%-27.70%
44
Neutral
$4.89B-122.04%-40.75%
43
Neutral
$3.52B-34.78%-34.96%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
VCYT
Veracyte
44.61
1.85
4.33%
TVTX
Travere Therapeutics
35.00
16.23
86.47%
CELC
Celcuity
105.63
92.81
723.95%
IMVT
Immunovant
22.84
-5.86
-20.42%
ARQT
Arcutis Biotherapeutics
31.20
18.62
148.01%
IRON
Disc Medicine
93.26
28.60
44.23%

Veracyte Corporate Events

Veracyte Inc. Reports Robust Q3 Earnings Performance
Nov 6, 2025

Veracyte Inc. recently held its earnings call, revealing a strong quarter marked by record revenue growth and profitability. The company showcased robust performance from its core testing business, particularly Decipher and Afirma, achieving a significant milestone by reaching its adjusted EBITDA margin target ahead of schedule. Despite these achievements, challenges remain, including declining biopharmaceutical revenue, competitive pressures from new technologies, and a slight decrease in testing ASP.

Veracyte Reports Strong Q3 2025 Financial Performance
Nov 5, 2025

Veracyte, Inc., a prominent player in the cancer diagnostics industry, specializes in providing high-value genomic tests that aid clinicians in diagnosing and treating cancer effectively. In its latest earnings report for the third quarter of 2025, Veracyte announced a significant increase in both total and testing revenues, with the latter reaching $127.8 million, marking a 17% rise year-over-year. The company also reported a net income of $19.1 million, reflecting a 26% improvement from the previous year, and an adjusted EBITDA of $39.7 million, showcasing a 45% growth.

Veracyte Inc’s Earnings Call Highlights Robust Growth and Strategic Milestones
Aug 8, 2025

Veracyte’s latest earnings call exuded a positive sentiment, marked by robust revenue and volume growth, alongside significant strategic milestones. The company showcased promising future product launches, despite facing some financial challenges such as a decline in product revenue and increased operating expenses. However, these challenges were overshadowed by the positive highlights, setting a hopeful tone for the company’s future.

Veracyte Reports Strong Q2 2025 Revenue Growth
Aug 7, 2025

Veracyte, Inc., a prominent player in the cancer diagnostics sector, is dedicated to enhancing cancer care through its innovative genomic tests and bioinformatic capabilities. In its latest earnings report for the second quarter of 2025, Veracyte reported a 14% increase in total revenue, reaching $130.2 million, driven by strong performance in its Decipher and Afirma tests. The company also recorded a significant increase in testing volume, with Decipher achieving a 28% growth. Despite a GAAP net loss of $1.0 million due to a $20.5 million impairment charge, Veracyte’s adjusted EBITDA improved by 49% year-over-year to $35.8 million. The company’s strategic focus on expanding its Decipher test for metastatic cancer patients and the successful restructuring of its French subsidiary are key highlights. Looking ahead, Veracyte has raised its full-year revenue guidance, reflecting confidence in sustained growth, supported by its robust platform and expanding clinical evidence base.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 25, 2025