Record Revenue Growth
Veracyte reported total revenue growth of 14% year-over-year to approximately $132 million in Q3 2025. Core testing business revenue grew by 18%, with significant contributions from Decipher (26% volume growth) and Afirma (13% volume growth).
Strong Profitability
Adjusted EBITDA margin reached a record 30%, representing a 650 basis point improvement from the prior year. This performance was well ahead of expectations, with the company achieving its goal of a 25% adjusted EBITDA margin more than a year ahead of internal plans.
Decipher's Clinical Utility and Growth
Decipher delivered approximately 26,700 tests in Q3, marking the 14th consecutive quarter of over 25% year-over-year volume growth. The test is increasingly recognized by physicians for its clinical utility across all risk categories, particularly in high-risk localized and metastatic patients.
Afirma's Continued Success
Afirma achieved 13% volume growth in Q3 2025, driven by new account wins and increased utilization per account. The operational efficiency program is progressing well, with a transition to a new transcriptome workflow expected to be completed by year-end.
Positive Financial Outlook
Veracyte raised its 2025 total revenue guidance to $506 million to $510 million, up from previous guidance. The adjusted EBITDA margin guidance was also raised to exceed 25% for the year.