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Upstream Bio, Inc. (UPB)
NASDAQ:UPB
Verekitug
Severe Asthma
Phase II
Recruiting
A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR)
May 09, 2025
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Verekitug
Chronic Obstructive Pulmonary Disease
Phase II
Recruiting
A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD
May 09, 2025
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Verekitug (Upb-101)
Severe Asthma
Phase II
Active Not Recruiting
A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALIANT)
Dec 24, 2023
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Verekitug (Upb-101)
Chronic Rhinosinusitis With Nasal Polyps
Phase II
Completed
A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Participants With Chronic Rhinosinusitis With Nasal Polyps
Dec 01, 2023
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Upb-101
Asthma
Phase I
Completed
Safety and Biologic Impact (Pharmacodynamics) of Repeated Injections and Increasing Amounts of UPB-101 in Asthmatics
Jun 29, 2022
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Upstream Bio, Inc. (UPB) have in its pipeline
UPB is currently developing the following drugs: Verekitug, Verekitug, Verekitug (Upb-101). These drug candidates are in various stages of clinical development as the company works toward FDA approval.