Upstream Bio, Inc. (UPB)
NASDAQ:UPB
Total Valuation
Upstream Bio, Inc. has a market cap or net worth of $516.99M. The enterprise value is $416.68M.
Market Cap$516.99M
Enterprise Value$416.68M
Share Statistics
Upstream Bio, Inc. has 54,419,987 shares outstanding. The number of shares has decreased by -2.65% in one year.
Shares Outstanding54,419,987
Owned by Insiders8.75%
Owned by Institutions44.29%
Financial Efficiency
Upstream Bio, Inc.’s return on equity (ROE) is -0.42 and return on invested capital (ROIC) is -47.02%.
Return on Equity (ROE)-0.42
Return on Assets (ROA)-0.41
Return on Invested Capital (ROIC)-47.02%
Return on Capital Employed (ROCE)-0.47
Revenue Per Employee54.88K
Profits Per Employee-2.76M
Employee Count52
Asset Turnover<0.01
Inventory Turnover0.00
Valuation Ratios
The current PE Ratio of Upstream Bio, Inc. is ―. Upstream Bio, Inc.’s PEG ratio is -0.13.
PE Ratio―
PS Ratio512.30
PB Ratio4.30
Price to Fair Value4.30
Price to FCF-10.97
Price to Operating Cash Flow-3.87
PEG Ratio-0.13
Income Statement
In the last 12 months, Upstream Bio, Inc. had revenue of 2.85M and earned -143.44M in profits. Earnings per share was -2.66.
Revenue2.85M
Gross Profit2.67M
Operating Income-160.36M
Pretax Income-143.44M
Net Income-143.44M
EBITDA-160.36M
Earnings Per Share (EPS)-2.66
Cash Flow
In the last 12 months, operating cash flow was -133.28M and capital expenditures -47.00K, giving a free cash flow of -133.32M billion.
Operating Cash Flow-133.28M
Free Cash Flow-133.32M
Free Cash Flow per Share-2.45
Dividends & Yields
Upstream Bio, Inc. pays an annual dividend of ―, resulting in a dividend yield of ―
Dividend Per Share―
Dividend Yield―
Payout RatioN/A
Free Cash Flow Yield―
Earnings Yield―
Stock Price Statistics
Beta1.14
52-Week Price Change49.37%
50-Day Moving Average14.62
200-Day Moving Average19.01
Relative Strength Index (RSI)44.01
Average Volume (3m)388.50K
Important Dates
Upstream Bio, Inc. upcoming earnings date is May 12, 2026, Before Open (Confirmed).
Last Earnings DateMar 18, 2026
Next Earnings DateMay 12, 2026
Ex-Dividend Date―
Financial Position
Upstream Bio, Inc. as a current ratio of 26.15, with Debt / Equity ratio of 0.37%
Current Ratio26.15
Quick Ratio26.15
Debt to Market Cap<0.01
Net Debt to EBITDA0.63
Interest Coverage Ratio0.00
Taxes
In the past 12 months, Upstream Bio, Inc. has paid 0.00 in taxes.
Income Tax0.00
Effective Tax Rate0.00
Enterprise Valuation
Upstream Bio, Inc. EV to EBITDA ratio is -8.49, with an EV/FCF ratio of -10.22.
EV to Sales477.15
EV to EBITDA-8.49
EV to Free Cash Flow-10.22
EV to Operating Cash Flow-10.22
Balance Sheet
Upstream Bio, Inc. has $341.51M in cash and marketable securities with $1.27M in debt, giving a net cash position of $340.24M billion.
Cash & Marketable Securities$341.51M
Total Debt$1.27M
Net Cash$340.24M
Net Cash Per Share$6.25
Tangible Book Value Per Share$6.31
Margins
Gross margin is 96.92%, with operating margin of -5618.82%, and net profit margin of -5026.03%.
Gross Margin96.92%
Operating Margin-5618.82%
Pretax Margin-5026.03%
Net Profit Margin-5026.03%
EBITDA Margin-5618.82%
EBIT Margin-5618.82%
Analyst Forecast
The average price target for Upstream Bio, Inc. is $44.00, which is 11.43% higher than the current price. The consensus rating is Strong Buy
Price Target$44.00
Price Target Upside45.21% Upside
Analyst ConsensusStrong Buy
Analyst Count7
Revenue Growth Forecast―
EPS Growth Forecast―