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Upstream Bio, Inc. (UPB)
NASDAQ:UPB
Total Valuation
Upstream Bio, Inc. has a market cap or net worth of $932.63M. The enterprise value is $198.38M.
Market Cap$932.63M
Enterprise Value$198.38M
Share Statistics
Upstream Bio, Inc. has 53,909,428 shares outstanding. The number of shares has decreased by -2.65% in one year.
Shares Outstanding53,909,428
Owned by Insiders28.89%
Owned by Institutions46.32%
Financial Efficiency
Upstream Bio, Inc.’s return on equity (ROE) is -0.13 and return on invested capital (ROIC) is -16.46%.
Return on Equity (ROE)-0.13
Return on Assets (ROA)-0.13
Return on Invested Capital (ROIC)-16.46%
Return on Capital Employed (ROCE)-0.17
Revenue Per Employee45.58K
Profits Per Employee-1.21M
Employee Count52
Asset Turnover<0.01
Inventory Turnover0.00
Valuation Ratios
The current PE Ratio of Upstream Bio, Inc. is ―. Upstream Bio, Inc.’s PEG ratio is ―.
PE Ratio―
PS Ratio―
PB Ratio―
Price to Fair Value1.80
Price to FCF―
Price to Operating Cash Flow-8.76
PEG Ratio―
Income Statement
In the last 12 months, Upstream Bio, Inc. had revenue of 2.37M and earned -62.81M in profits. Earnings per share was -1.49.
Revenue2.37M
Gross Profit2.37M
Operating Income-77.76M
Pretax Income-62.81M
Net Income-62.81M
EBITDA-77.67M
Earnings Per Share (EPS)-1.49
Cash Flow
In the last 12 months, operating cash flow was -113.98M and capital expenditures -558.00K, giving a free cash flow of -114.54M billion.
Operating Cash Flow-113.98M
Free Cash Flow-114.54M
Free Cash Flow per Share-2.12
Dividends & Yields
Upstream Bio, Inc. pays an annual dividend of ―, resulting in a dividend yield of ―
Dividend Per Share―
Dividend Yield―
Payout RatioN/A
Free Cash Flow Yield―
Earnings Yield―
Stock Price Statistics
Beta0.78
52-Week Price Change-28.31%
50-Day Moving Average13.82
200-Day Moving Average12.51
Relative Strength Index (RSI)55.28
Average Volume (3m)485.14K
Important Dates
Upstream Bio, Inc. upcoming earnings date is Nov 6, 2025, Before Open (Confirmed).
Last Earnings DateAug 6, 2025
Next Earnings DateNov 6, 2025
Ex-Dividend Date―
Financial Position
Upstream Bio, Inc. as a current ratio of 44.63, with Debt / Equity ratio of 0.38%
Current Ratio44.63
Quick Ratio44.63
Debt to Market Cap<0.01
Net Debt to EBITDA4.17
Interest Coverage Ratio0.00
Taxes
In the past 12 months, Upstream Bio, Inc. has paid 0.00 in taxes.
Income Tax0.00
Effective Tax Rate0.00
Enterprise Valuation
Upstream Bio, Inc. EV to EBITDA ratio is -6.69, with an EV/FCF ratio of -8.71.
EV to Sales219.41
EV to EBITDA-6.69
EV to Free Cash Flow-8.71
EV to Operating Cash Flow-8.79
Balance Sheet
Upstream Bio, Inc. has $393.58M in cash and marketable securities with $1.56M in debt, giving a net cash position of -$392.02M billion.
Cash & Marketable Securities$393.58M
Total Debt$1.56M
Net Cash-$392.02M
Net Cash Per Share-$7.27
Tangible Book Value Per Share$9.15
Margins
Gross margin is 100.00%, with operating margin of -3281.18%, and net profit margin of -2650.04%.
Gross Margin100.00%
Operating Margin-3281.18%
Pretax Margin-2650.04%
Net Profit Margin-2650.04%
EBITDA Margin-3277.43%
EBIT Margin-3281.18%
Analyst Forecast
The average price target for Upstream Bio, Inc. is $41.83, which is 11.43% higher than the current price. The consensus rating is Strong Buy
Price Target$41.83
Price Target Upside149.58% Upside
Analyst ConsensusStrong Buy
Analyst Count5
Revenue Growth Forecast―
EPS Growth Forecast―