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HLS Therapeutics Inc (TSE:HLS)
TSX:HLS
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HLS Therapeutics Inc (HLS) AI Stock Analysis

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TSE:HLS

HLS Therapeutics Inc

(TSX:HLS)

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Neutral 44 (OpenAI - 4o)
Rating:44Neutral
Price Target:
C$4.50
▼(-9.82% Downside)
HLS Therapeutics Inc. faces significant challenges in financial performance, particularly in revenue growth and profitability, which are reflected in its negative P/E ratio. Technical analysis indicates bearish momentum, further impacting the stock's outlook. While there are positive aspects such as strong gross margins and cash flow management, these are overshadowed by the company's current struggles.
Positive Factors
Strong Gross Margins
Strong gross margins reflect effective cost control and pricing power, which can support profitability even amid revenue challenges.
Positive Cash Flow Trends
Improved cash flow generation enhances financial flexibility, allowing for reinvestment in growth opportunities and debt reduction.
Bempedoic Acid Launch
The upcoming launch of bempedoic acid could drive future growth by expanding the product portfolio and capturing new market segments.
Negative Factors
Revenue Decline
Declining revenue indicates challenges in market demand or competitive pressures, which could impact long-term growth and profitability.
Clozaril Revenue Decline
Declining sales in a key product like Clozaril suggest competitive pressures and market saturation, affecting overall revenue stability.
Negative Return on Equity
Negative ROE reflects inefficiencies in using equity capital, which may hinder the company's ability to attract investment and grow.

HLS Therapeutics Inc (HLS) vs. iShares MSCI Canada ETF (EWC)

HLS Therapeutics Inc Business Overview & Revenue Model

Company DescriptionHLS Therapeutics Inc., a specialty pharmaceutical company, acquires and commercializes pharmaceutical products in the specialty central nervous system and cardiovascular (CV) markets in Canada, the United States, and internationally. The company's product portfolio includes Clozaril, an atypical antipsychotic used in the treatment of schizophrenia; Vascepa, an icosapent ethyl capsules; and PERSERIS, an injectable risperidone product for the treatment of schizophrenia. It also offers MyCare psychiatry lab assays and MyCare Insite point of care therapeutic drug-level monitoring tests. In addition, the company holds the U.S. marketing rights of Absorica, a commercial stage dermatology product; Canadian rights of Trinomia for CV therapeutics; and a portfolio of royalty interests of four healthcare products. HLS Therapeutics Inc. was founded in 2018 and is headquartered in Etobicoke, Canada.
How the Company Makes MoneyHLS Therapeutics generates revenue through the sales of its pharmaceutical products, which include prescription medications for CNS and cardiovascular conditions. The company employs a revenue model that relies on both direct sales to healthcare providers and partnerships with distributors and pharmacies. Key revenue streams include sales from marketed products, royalties from licensing agreements, and potential milestone payments from collaborative partnerships. Additionally, HLS may benefit from strategic alliances with other pharmaceutical companies that enhance its market reach and product offerings, contributing to its overall earnings.

HLS Therapeutics Inc Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 12, 2026
Earnings Call Sentiment Neutral
The earnings call reflects a mixed performance, with strong adjusted EBITDA growth and a solid financial position, but challenges in revenue growth and competitive pressures in the Clozaril business. While there are significant achievements, the revenue decline and lower-than-expected growth in certain areas indicate a balanced sentiment.
Q3-2025 Updates
Positive Updates
Strong Adjusted EBITDA Growth
Adjusted EBITDA reached $4.9 million in Q3, up 19% year-over-year, and $13.9 million year-to-date, up 25% compared to the same period in 2024.
Vascepa Prescription Growth
Vascepa prescriptions grew 24% year-to-date, with Q3 being its most profitable since launch.
Debt Reduction and Financial Strengthening
Significant debt reduction, with net debt at $43.5 million, down from $50 million at the end of 2024, and a new favorable credit agreement.
Bempedoic Acid Launch Preparations
Preparations for the Q2 2026 launch of bempedoic acid, with potential to address a large Canadian market.
Negative Updates
Revenue Decline
Total revenue for Q3 was $13.5 million, down from $14.1 million in Q3 last year. Year-to-date revenue was $40.3 million, compared to $41.1 million in the same period last year.
Clozaril Revenue Decline
Projected decline of 4% to 5% for the Canadian Clozaril business in local currency for the full year, due to competitive pressures and inventory fluctuations.
Vascepa Revenue Growth Below Expectations
Vascepa revenue growth is expected in the mid-teens for the full year, below the prior range of 18% to 26% growth.
Company Guidance
During the Q3 2025 Financial Results Conference Call for HLS Therapeutics, the company reported an adjusted EBITDA of $4.9 million for the third quarter, marking a 19% increase year-over-year, and $13.9 million year-to-date, up 25% from the same period in 2024. Total revenue for Q3 was $13.5 million, slightly down from $14.1 million in the previous year, while year-to-date revenue was $40.3 million compared to $41.1 million. Canadian product sales in local currency grew by 2% year-to-date, despite a 4% revenue decline in Q3, with Vascepa prescriptions showing a substantial 24% growth year-to-date. However, Vascepa's revenue growth is expected to be in the mid-teens for the full year, revised from the initial 18% to 26% forecast. Clozaril's Canadian business projected a 4% to 5% decline due to inventory fluctuations and competitive pressures, although U.S. Clozaril sales were up 1% year-to-date. The company aims to reach an adjusted EBITDA growth range of 17% to 23% for the full year, translating to $19.5 million to $20.5 million, with an anticipated consolidated revenue estimate of $55 million to $56 million. Looking ahead, HLS Therapeutics plans to launch bempedoic acid in Q2 2026, expecting it to contribute to future growth, and has positioned itself to leverage operational synergies with Vascepa, maintaining financial discipline and reducing debt while exploring strategic growth opportunities.

HLS Therapeutics Inc Financial Statement Overview

Summary
HLS Therapeutics Inc. demonstrates strong gross margins and positive cash flow trends, but faces significant challenges in revenue growth and profitability. The balance sheet reflects moderate leverage, but negative returns on equity indicate inefficiencies in generating shareholder value. Overall, the company shows potential in cash flow management but needs to address revenue and profitability issues to improve its financial health.
Income Statement
45
Neutral
HLS Therapeutics Inc. has faced declining revenue growth, with a significant drop of 61.3% in TTM. The gross profit margin remains strong at 82.6%, indicating efficient cost management. However, the company struggles with profitability, as evidenced by a negative net profit margin of -26.7% and negative EBIT margin. The EBITDA margin is positive at 27.5%, showing some operational efficiency.
Balance Sheet
50
Neutral
The company's debt-to-equity ratio is moderate at 0.83, suggesting manageable leverage. However, the return on equity is negative at -21.2%, indicating challenges in generating returns for shareholders. The equity ratio stands at 44.7%, reflecting a stable capital structure.
Cash Flow
55
Neutral
HLS Therapeutics shows a positive free cash flow growth rate of 9.3% in TTM, indicating improved cash generation. The operating cash flow to net income ratio is 0.47, suggesting moderate cash conversion efficiency. The free cash flow to net income ratio is high at 91.3%, highlighting strong cash flow relative to net income.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue56.42M56.62M63.07M61.47M60.01M56.11M
Gross Profit46.60M47.62M55.45M56.49M56.04M52.48M
EBITDA15.49M17.22M12.88M18.00M25.41M23.19M
Net Income-15.04M-19.66M-27.53M-23.60M-13.12M-15.33M
Balance Sheet
Total Assets149.07M159.90M209.06M241.65M275.90M303.91M
Cash, Cash Equivalents and Short-Term Investments12.15M17.46M21.95M20.72M21.18M20.61M
Total Debt55.57M66.45M87.62M97.34M97.57M107.12M
Total Liabilities82.51M88.56M111.36M116.33M115.17M134.66M
Stockholders Equity66.56M71.34M97.70M125.32M160.74M169.25M
Cash Flow
Free Cash Flow11.73M7.99M15.60M6.79M11.92M-35.33M
Operating Cash Flow12.85M8.00M15.79M16.94M16.43M9.34M
Investing Cash Flow-2.62M11.73M-189.00K-10.15M-4.51M-44.68M
Financing Cash Flow-30.49M-23.36M-14.64M-6.86M-11.40M9.56M

HLS Therapeutics Inc Technical Analysis

Technical Analysis Sentiment
Negative
Last Price4.99
Price Trends
50DMA
5.43
Negative
100DMA
5.28
Negative
200DMA
4.89
Positive
Market Momentum
MACD
-0.15
Positive
RSI
39.63
Neutral
STOCH
72.02
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TSE:HLS, the sentiment is Negative. The current price of 4.99 is below the 20-day moving average (MA) of 5.19, below the 50-day MA of 5.43, and above the 200-day MA of 4.89, indicating a neutral trend. The MACD of -0.15 indicates Positive momentum. The RSI at 39.63 is Neutral, neither overbought nor oversold. The STOCH value of 72.02 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TSE:HLS.

HLS Therapeutics Inc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
71
Outperform
$375.57M22.4016.32%94.28%5.23%
61
Neutral
5.24%-7.99%
57
Neutral
C$86.45M64.480.87%2.14%-83.06%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
44
Neutral
C$169.51M-8.20-20.49%0.73%33.51%
38
Underperform
$146.00M-341.20%21.17%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TSE:HLS
HLS Therapeutics Inc
4.99
1.48
42.17%
TSE:TH
Theratechnologies
4.47
2.79
166.07%
TSE:CPH
Cipher Pharmaceuticals
14.78
0.03
0.20%
TSE:MDP
Medexus Pharmaceuticals Inc
2.71
0.10
3.83%
TSE:CRDL
Cardiol Therapeutics
1.44
-0.76
-34.55%

HLS Therapeutics Inc Corporate Events

HLS Therapeutics Reports Mixed Earnings Amid Growth Challenges
Nov 14, 2025

In the latest earnings call, HLS Therapeutics presented a mixed performance, showcasing strong adjusted EBITDA growth and a solid financial position, yet facing challenges in revenue growth and competitive pressures, particularly in the Clozaril business. Despite significant achievements, the decline in revenue and lower-than-expected growth in certain areas painted a balanced sentiment among stakeholders.

Business Operations and StrategyFinancial DisclosuresPrivate Placements and FinancingProduct-Related Announcements
HLS Therapeutics Reports Strong Q3 2025 Results and Prepares for New Product Launch
Positive
Nov 13, 2025

HLS Therapeutics Inc. reported a strong financial performance for Q3 2025, with a 19% increase in Adjusted EBITDA and a 67% rise in cash from operations. The company secured a new credit facility with improved terms and is preparing for the launch of bempedoic acid in Canada, expected to address significant unmet needs in cardiovascular treatment. Despite challenges in the Canadian market, HLS remains optimistic about future growth, leveraging operational synergies and maintaining a strong balance sheet to explore additional opportunities.

The most recent analyst rating on (TSE:HLS) stock is a Hold with a C$5.50 price target. To see the full list of analyst forecasts on HLS Therapeutics Inc stock, see the TSE:HLS Stock Forecast page.

Financial Disclosures
HLS Therapeutics to Announce Q3 2025 Financial Results
Neutral
Oct 30, 2025

HLS Therapeutics Inc. announced it will release its financial results for the third quarter of 2025 on November 13, 2025, followed by a conference call to discuss the results. This announcement is significant for stakeholders as it provides insights into the company’s financial performance and strategic positioning in the pharmaceutical industry, particularly in its focus areas of psychiatric and cardiovascular treatments.

The most recent analyst rating on (TSE:HLS) stock is a Hold with a C$5.50 price target. To see the full list of analyst forecasts on HLS Therapeutics Inc stock, see the TSE:HLS Stock Forecast page.

Business Operations and Strategy
HLS Therapeutics and Amarin Highlight Cardiovascular Advances at Canadian Congress
Positive
Oct 14, 2025

HLS Therapeutics Inc., in collaboration with Amarin Corporation, announced the presentation of significant scientific data at the Canadian Cardiovascular Congress, emphasizing the therapeutic potential of Icosapent Ethyl and Eicosapentaenoic Acid. These presentations underscore HLS’s commitment to enhancing cardiovascular care and exploring the mechanistic effects of these compounds, potentially impacting the treatment of cardiometabolic conditions and inflammation-related endothelial functions.

The most recent analyst rating on (TSE:HLS) stock is a Hold with a C$5.50 price target. To see the full list of analyst forecasts on HLS Therapeutics Inc stock, see the TSE:HLS Stock Forecast page.

Business Operations and StrategyStock BuybackPrivate Placements and Financing
HLS Therapeutics Secures New Credit Agreement for Financial Flexibility
Positive
Aug 20, 2025

HLS Therapeutics Inc. has announced a new credit agreement with National Bank of Canada, replacing its previous facility with JP Morgan Chase Bank. The new CAD $107 million facility, which includes a CAD $79 million term loan, provides enhanced financial flexibility and reduces foreign exchange exposure. The agreement reflects improved terms with lower interest rates, benefiting the company’s cash flow and supporting its strategic priorities like share buybacks and portfolio expansion.

The most recent analyst rating on (TSE:HLS) stock is a Buy with a C$9.50 price target. To see the full list of analyst forecasts on HLS Therapeutics Inc stock, see the TSE:HLS Stock Forecast page.

Business Operations and StrategyFinancial Disclosures
HLS Therapeutics Reports Strong Q2 2025 Financials and Strategic Expansion
Positive
Aug 14, 2025

HLS Therapeutics Inc. reported a 21% increase in adjusted EBITDA for Q2 2025 and a 29% rise year-to-date, with significant growth in cash from operations. The company made substantial debt repayments and expanded its cardiovascular portfolio by licensing Canadian rights to NEXLETOL and NEXLIZET from Esperion Therapeutics. These developments are expected to strengthen HLS’s market position and support its growth trajectory, with plans to launch the new products in Canada by Q2 2026.

The most recent analyst rating on (TSE:HLS) stock is a Hold with a C$3.50 price target. To see the full list of analyst forecasts on HLS Therapeutics Inc stock, see the TSE:HLS Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 14, 2025