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HLS Therapeutics Inc (TSE:HLS)
TSX:HLS
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HLS Therapeutics Inc (HLS) AI Stock Analysis

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TSE:HLS

HLS Therapeutics Inc

(TSX:HLS)

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Neutral 55 (OpenAI - 5.2)
Rating:55Neutral
Price Target:
C$4.50
▼(-3.23% Downside)
Action:Reiterated
Date:05/16/26
The score is driven primarily by solid and improving cash-flow performance and better gross margin, offset by continued net losses/negative ROE. Technical indicators are neutral-to-mixed with the stock still below the 200-day average, and valuation is constrained by a negative P/E with no dividend yield provided.
Positive Factors
Cash generation
Sustained operating cash flow and very strong free cash flow provide durable internal funding to support commercialization, acquisitions, and debt reduction. This cash conversion cushions the business versus accounting losses and enables strategic flexibility over the next several quarters.
Negative Factors
Persistent net losses & negative ROE
Material negative net margin and negative return on equity indicate the business is not yet producing accounting profits; over time, continued losses can erode shareholder equity, restrict capital options, and hinder trust from lenders and partners unless profitability inflects.
Read all positive and negative factors
Positive Factors
Negative Factors
Cash generation
Sustained operating cash flow and very strong free cash flow provide durable internal funding to support commercialization, acquisitions, and debt reduction. This cash conversion cushions the business versus accounting losses and enables strategic flexibility over the next several quarters.
Read all positive factors

HLS Therapeutics Inc (HLS) vs. iShares MSCI Canada ETF (EWC)

HLS Therapeutics Inc Business Overview & Revenue Model

Company Description
HLS Therapeutics Inc., a specialty pharmaceutical company, acquires and commercializes pharmaceutical products in the specialty central nervous system and cardiovascular (CV) markets in Canada, the United States, and internationally. The company's...
How the Company Makes Money
HLS primarily makes money by selling prescription pharmaceutical products that it has licensed or acquired, generating revenue from product sales through wholesaler and pharmacy channels in its commercial territories (primarily Canada and the Unit...

HLS Therapeutics Inc Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Aug 06, 2026
Earnings Call Sentiment Neutral
The earnings call reflects a mixed performance, with strong adjusted EBITDA growth and a solid financial position, but challenges in revenue growth and competitive pressures in the Clozaril business. While there are significant achievements, the revenue decline and lower-than-expected growth in certain areas indicate a balanced sentiment.
Positive Updates
Strong Adjusted EBITDA Growth
Adjusted EBITDA reached $4.9 million in Q3, up 19% year-over-year, and $13.9 million year-to-date, up 25% compared to the same period in 2024.
Negative Updates
Revenue Decline
Total revenue for Q3 was $13.5 million, down from $14.1 million in Q3 last year. Year-to-date revenue was $40.3 million, compared to $41.1 million in the same period last year.
Read all updates
Q3-2025 Updates
Negative
Strong Adjusted EBITDA Growth
Adjusted EBITDA reached $4.9 million in Q3, up 19% year-over-year, and $13.9 million year-to-date, up 25% compared to the same period in 2024.
Read all positive updates
Company Guidance
During the Q3 2025 Financial Results Conference Call for HLS Therapeutics, the company reported an adjusted EBITDA of $4.9 million for the third quarter, marking a 19% increase year-over-year, and $13.9 million year-to-date, up 25% from the same period in 2024. Total revenue for Q3 was $13.5 million, slightly down from $14.1 million in the previous year, while year-to-date revenue was $40.3 million compared to $41.1 million. Canadian product sales in local currency grew by 2% year-to-date, despite a 4% revenue decline in Q3, with Vascepa prescriptions showing a substantial 24% growth year-to-date. However, Vascepa's revenue growth is expected to be in the mid-teens for the full year, revised from the initial 18% to 26% forecast. Clozaril's Canadian business projected a 4% to 5% decline due to inventory fluctuations and competitive pressures, although U.S. Clozaril sales were up 1% year-to-date. The company aims to reach an adjusted EBITDA growth range of 17% to 23% for the full year, translating to $19.5 million to $20.5 million, with an anticipated consolidated revenue estimate of $55 million to $56 million. Looking ahead, HLS Therapeutics plans to launch bempedoic acid in Q2 2026, expecting it to contribute to future growth, and has positioned itself to leverage operational synergies with Vascepa, maintaining financial discipline and reducing debt while exploring strategic growth opportunities.

HLS Therapeutics Inc Financial Statement Overview

Summary
Strong cash generation (TTM operating cash flow ~$19.8M; free cash flow ~$18.4M with strong growth) and improved gross margin support the business. However, profitability remains the key weakness with negative EBIT, a materially negative net margin (~-22%), and negative ROE (~-19%), keeping the score moderate despite improving trends and reduced leverage.
Income Statement
44
Neutral
Balance Sheet
55
Neutral
Cash Flow
73
Positive
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue55.76M56.47M56.62M63.07M61.47M60.01M
Gross Profit34.41M24.01M47.62M55.45M56.49M56.04M
EBITDA17.79M18.02M17.22M12.88M18.00M25.41M
Net Income-10.27M-12.65M-19.66M-27.53M-23.60M-13.12M
Balance Sheet
Total Assets131.18M137.28M159.90M209.06M241.65M275.90M
Cash, Cash Equivalents and Short-Term Investments12.33M11.70M17.46M21.95M20.72M21.18M
Total Debt43.96M49.73M66.45M87.62M97.34M97.57M
Total Liabilities72.57M75.72M88.56M111.36M116.33M115.17M
Stockholders Equity58.61M61.56M71.34M97.70M125.32M160.74M
Cash Flow
Free Cash Flow18.39M15.81M7.99M15.60M6.79M11.92M
Operating Cash Flow19.79M16.02M8.00M15.79M16.94M16.43M
Investing Cash Flow-2.06M-1.73M11.73M-189.00K-10.15M-4.51M
Financing Cash Flow-23.36M-20.52M-23.36M-14.64M-6.86M-11.40M

HLS Therapeutics Inc Technical Analysis

Technical Analysis Sentiment
Negative
Last Price4.65
Price Trends
50DMA
4.52
Positive
100DMA
4.56
Positive
200DMA
4.92
Negative
Market Momentum
MACD
0.02
Positive
RSI
47.73
Neutral
STOCH
51.19
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TSE:HLS, the sentiment is Negative. The current price of 4.65 is below the 20-day moving average (MA) of 4.65, above the 50-day MA of 4.52, and below the 200-day MA of 4.92, indicating a neutral trend. The MACD of 0.02 indicates Positive momentum. The RSI at 47.73 is Neutral, neither overbought nor oversold. The STOCH value of 51.19 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TSE:HLS.

HLS Therapeutics Inc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
85
Outperform
C$427.76M13.6825.69%27.57%226.76%
77
Outperform
C$160.96M17.4322.05%1.60%20.13%17.08%
69
Neutral
C$801.92M13.850.73%36.93%-47.43%
66
Neutral
C$126.62M294.90-0.52%-7.44%-108.29%
55
Neutral
C$145.11M-10.87-16.54%-2.35%42.42%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
38
Underperform
C$663.17K0.459.47%122.30%75.74%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TSE:HLS
HLS Therapeutics Inc
4.59
-0.06
-1.29%
TSE:GUD
Knight Therapeutics
8.33
2.57
44.62%
TSE:CPH
Cipher Pharmaceuticals
16.88
4.43
35.58%
TSE:AQS
Aequus Pharmaceuticals
0.01
0.00
0.00%
TSE:MDP
Medexus Pharmaceuticals Inc
3.97
1.25
45.96%
TSE:RX
Biosyent
13.86
2.30
19.89%

HLS Therapeutics Inc Corporate Events

Business Operations and Strategy
HLS Therapeutics to Highlight CNS and Cardiovascular Portfolio at Bloom Burton Investor Conference
Positive
Apr 14, 2026
HLS Therapeutics Inc. will showcase its strategy and portfolio in psychiatric and cardiovascular treatments at the 2026 Bloom Burton Co. Healthcare Investor Conference in Toronto, where CEO Craig Millian is scheduled to present on April 21. The c...
Business Operations and StrategyFinancial DisclosuresPrivate Placements and Financing
HLS Therapeutics Lifts Profitability, Cuts Debt as It Expands Cardiovascular Portfolio
Positive
Mar 12, 2026
HLS Therapeutics reported fiscal 2025 revenue of $55.5 million, with Adjusted EBITDA rising 18% to $19.6 million and cash from operations more than doubling to $17.1 million. The company cut operating expenses, reduced long-term debt by 26%, and l...
Business Operations and StrategyProduct-Related Announcements
HLS Therapeutics launches NILEMDO in Canada to tackle unmet cholesterol treatment needs
Positive
Mar 5, 2026
HLS Therapeutics has launched NILEMDO (bempedoic acid) across Canada, offering a first-in-class, once-daily oral non-statin therapy for adults who cannot reach LDL-cholesterol targets on existing treatments or are statin intolerant. Supported by t...
Business Operations and StrategyProduct-Related Announcements
HLS Therapeutics launches NILEMDO in Canada to target unmet LDL-cholesterol needs
Positive
Mar 5, 2026
HLS Therapeutics has launched NILEMDO, a once-daily oral non-statin therapy, across Canada for adults who cannot reach LDL-cholesterol targets with current treatments or who are statin intolerant. The drug, in-licensed from Esperion Therapeutics a...
Business Operations and StrategyFinancial Disclosures
HLS Therapeutics Sets March 12 Date for Fiscal 2025 Results and Investor Call
Neutral
Feb 26, 2026
HLS Therapeutics Inc. will release its fiscal 2025 fourth-quarter and full-year financial results on March 12, 2026, before markets open, and will host a conference call at 8:30 a.m. ET the same day, led by its CEO, CFO, and Chief Commercial Offic...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 16, 2026