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Medexus Pharmaceuticals Inc (TSE:MDP)
TSX:MDP
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Medexus Pharmaceuticals Inc (MDP) AI Stock Analysis

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TSE:MDP

Medexus Pharmaceuticals Inc

(TSX:MDP)

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Neutral 57 (OpenAI - 4o)
Rating:57Neutral
Price Target:
C$3.00
▲(11.11% Upside)
Medexus Pharmaceuticals Inc's overall stock score reflects a mixed financial performance with stable gross margins but declining revenue and cash flow. The technical analysis indicates bearish trends, while the high P/E ratio suggests overvaluation. The earnings call provided some optimism with successful product launches and cost reductions, but challenges remain with declining revenue and competitive pressures.
Positive Factors
Successful Product Launch
The successful launch of GRAFAPEX, with strong patient demand and positive cash flow contributions, indicates robust market acceptance and potential for sustained revenue growth.
Cost Reduction Initiatives
The significant reduction in manufacturing costs for IXINITY enhances margin sustainability and operational efficiency, strengthening the company's competitive position.
Positive Reimbursement Developments
Improved reimbursement for GRAFAPEX under the NTAP program facilitates adoption, boosting long-term revenue potential and market penetration.
Negative Factors
Revenue Decline
The decline in net revenue suggests challenges in maintaining sales growth, which could impact future earnings and market share if not addressed.
Generic Competition Impact
The significant drop in demand for Rupall due to generic competition highlights vulnerability in product lines, affecting revenue stability.
Decreased Demand for Key Products
Falling demand for Rasuvo and Metoject indicates competitive pressures and market challenges, potentially reducing future revenue streams.

Medexus Pharmaceuticals Inc (MDP) vs. iShares MSCI Canada ETF (EWC)

Medexus Pharmaceuticals Inc Business Overview & Revenue Model

Company DescriptionMedexus Pharmaceuticals Inc. (MDP) is a biopharmaceutical company focused on the development and commercialization of innovative therapeutic solutions for patients with rare diseases and unmet medical needs. Operating primarily in the pharmaceutical sector, Medexus specializes in a range of products, including hematology and autoimmune therapies, with a commitment to enhancing patient outcomes through effective treatments. The company is dedicated to expanding its portfolio through strategic partnerships and collaborations, as well as leveraging its expertise in drug development and commercialization.
How the Company Makes MoneyMedexus Pharmaceuticals generates revenue primarily through the sale of its pharmaceutical products, which include proprietary and licensed treatments for various conditions. The company has established key revenue streams through direct sales to healthcare providers and partnerships with other pharmaceutical companies for product distribution and co-marketing agreements. Additionally, Medexus benefits from government and private insurance reimbursements for its medications, which further contributes to its earnings. Significant partnerships with healthcare organizations and ongoing investment in research and development also play a crucial role in driving the company's revenue growth, as they enable Medexus to expand its portfolio and reach new markets.

Medexus Pharmaceuticals Inc Earnings Call Summary

Earnings Call Date:Nov 12, 2025
(Q2-2026)
|
Next Earnings Date:Feb 11, 2026
Earnings Call Sentiment Neutral
The call highlighted the successful launch and adoption of GRAFAPEX, with significant improvements in reimbursement and manufacturing cost reductions. However, the company faced challenges with declining revenue, adjusted EBITDA, and demand for key products due to competitive pressures.
Q2-2026 Updates
Positive Updates
Successful Launch of GRAFAPEX
GRAFAPEX exceeded prelaunch expectations with the strongest month of patient demand in October 2025. $6.2 million in net revenue was recognized in the first six months, and it is expected to positively contribute to quarterly operating cash flows by fiscal Q3 2026.
Positive Reimbursement Developments
Starting October 1, 2025, eligible procedures under Medicare using GRAFAPEX are eligible for additional reimbursement through the NTAP program, facilitating adoption.
Gross Margin Improvement
Gross margin for fiscal Q2 2026 was 55.7%, an improvement from 53.7% in the same period last year.
Cost Reduction in IXINITY Manufacturing
IXINITY's manufacturing process improvement initiative resulted in a 30% decrease in product level cost of goods since fiscal Q1 2021.
Negative Updates
Net Revenue Decline
Fiscal Q2 2026 net revenue was $24.7 million, a decrease compared to $26.3 million for the same period last year.
Decrease in Adjusted EBITDA
Fiscal Q2 2026 adjusted EBITDA was $4.4 million, a decrease from $6 million for the same period last year.
Rupall Facing Generic Competition
Rupall's unit demand decreased by 58% over three months due to generic competition following the loss of regulatory exclusivity.
Decreased Demand for Rasuvo and Metoject
Rasuvo and Metoject unit demand in the U.S. and Canada decreased by 2% and 9% respectively over the trailing 12 months.
Company Guidance
During the Medexus Pharmaceuticals Second Fiscal Quarter 2026 earnings call, considerable guidance was provided on the performance and outlook of GRAFAPEX. The company reported that product performance has exceeded prelaunch expectations, with October 2025 marking the strongest month of patient demand since the launch. By the end of September 2025, Medexus had engaged with 83% of U.S. transplant centers, with 29% having already ordered GRAFAPEX and 69% of those reordering. For the six months ending September 30, product-level net revenue from GRAFAPEX was $6.2 million, with the fiscal Q2 2026 revenue totaling $3.1 million. The company anticipates that GRAFAPEX will contribute positively to quarterly operating cash flows by fiscal Q3 2026, with expected underlying patient demand of approximately $3 million to $4 million. Additionally, the NTAP program's reimbursement eligibility is projected to significantly enhance adoption and utilization of GRAFAPEX. Overall, Medexus reported fiscal Q2 2026 net revenue of $24.7 million, a decrease from $26.3 million the previous year, with adjusted EBITDA at $4.4 million. Despite a modest net loss for the quarter, positive operating income was achieved, and the company remains optimistic about future growth opportunities.

Medexus Pharmaceuticals Inc Financial Statement Overview

Summary
Medexus Pharmaceuticals Inc shows a mixed financial performance. The company has a stable gross profit margin and improved leverage, but faces challenges with negative revenue growth and declining cash flow. Profitability and cash flow enhancement are needed to strengthen its financial position.
Income Statement
65
Positive
Medexus Pharmaceuticals Inc shows a mixed performance in its income statement. The company has maintained a stable gross profit margin around 52%, indicating efficient production and pricing strategies. However, the net profit margin is low at 2.07% TTM, reflecting limited profitability. Revenue growth has been negative recently, with a decline of 2.46% TTM, which could be a concern for future earnings potential. The EBIT and EBITDA margins are moderate, suggesting operational efficiency but room for improvement.
Balance Sheet
58
Neutral
The balance sheet reveals a moderate financial position. The debt-to-equity ratio has improved to 0.71 TTM from higher levels in previous years, indicating better leverage management. However, the return on equity is modest at 5.97% TTM, suggesting limited returns for shareholders. The equity ratio is not explicitly calculated, but the company's equity position has strengthened over time, which is a positive sign.
Cash Flow
60
Neutral
Cash flow analysis shows some challenges. The free cash flow growth rate is negative at -20.50% TTM, indicating a decline in cash generation. However, the operating cash flow to net income ratio is healthy at 0.25, suggesting good cash conversion. The free cash flow to net income ratio is high at 0.89, indicating efficient cash utilization despite the decline in free cash flow.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue105.66M108.33M113.05M108.10M76.70M79.66M
Gross Profit55.52M56.58M59.51M60.04M37.93M42.01M
EBITDA15.92M16.81M19.28M16.14M15.16M-23.61M
Net Income806.00K2.25M-214.00K1.22M-2.88M-28.26M
Balance Sheet
Total Assets153.79M171.84M155.73M161.33M139.22M148.51M
Cash, Cash Equivalents and Short-Term Investments9.33M23.97M5.25M13.07M10.02M18.70M
Total Debt21.89M37.18M49.90M94.72M54.86M56.40M
Total Liabilities100.83M119.69M125.41M187.70M151.82M130.50M
Stockholders Equity52.96M52.14M30.32M22.45M17.79M18.02M
Cash Flow
Free Cash Flow16.94M21.31M18.45M-1.81M-8.89M-5.72M
Operating Cash Flow19.76M24.03M18.71M-1.44M-1.18M5.04M
Investing Cash Flow-7.87M-6.00M-3.48M-1.72M-8.20M-11.70M
Financing Cash Flow-11.00M796.00K-23.05M6.41M663.00K18.68M

Medexus Pharmaceuticals Inc Technical Analysis

Technical Analysis Sentiment
Negative
Last Price2.70
Price Trends
50DMA
2.80
Negative
100DMA
2.85
Negative
200DMA
2.80
Negative
Market Momentum
MACD
-0.04
Positive
RSI
46.99
Neutral
STOCH
38.54
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TSE:MDP, the sentiment is Negative. The current price of 2.7 is below the 20-day moving average (MA) of 2.73, below the 50-day MA of 2.80, and below the 200-day MA of 2.80, indicating a bearish trend. The MACD of -0.04 indicates Positive momentum. The RSI at 46.99 is Neutral, neither overbought nor oversold. The STOCH value of 38.54 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TSE:MDP.

Medexus Pharmaceuticals Inc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
76
Outperform
C$126.23M15.1222.35%1.81%22.22%25.50%
59
Neutral
C$283.43M70.331.86%38.86%
57
Neutral
C$86.45M64.480.87%2.14%-83.06%
52
Neutral
C$13.57M-3.96-18.39%24.30%-68.60%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
21
Underperform
C$663.17K-0.81192.96%42.59%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TSE:MDP
Medexus Pharmaceuticals Inc
2.70
0.32
13.45%
TSE:AQS
Aequus Pharmaceuticals
0.01
0.00
0.00%
TSE:WIB
West Island Brands Inc
0.13
0.00
0.00%
TSE:MPH
Medicure
1.30
0.40
44.44%
TSE:RX
Biosyent
10.76
-0.74
-6.43%
TSE:OGI
OrganiGram Holdings
2.11
-0.08
-3.65%

Medexus Pharmaceuticals Inc Corporate Events

Financial DisclosuresProduct-Related Announcements
Medexus Pharmaceuticals Reports Strong GRAFAPEX Performance Amidst Revenue Challenges
Positive
Nov 13, 2025

Medexus Pharmaceuticals reported its fiscal Q2 2026 results, highlighting the strong performance of its product GRAFAPEX, which has exceeded expectations since its launch. Despite a decrease in overall net revenue due to competition and the termination of a previous agreement, GRAFAPEX’s success has positively impacted the company’s financials, with significant engagement from US transplant centers and expectations of accretive cash flows by Q4 2025. This positions Medexus well for future growth, despite challenges from generic competition affecting other products.

The most recent analyst rating on (TSE:MDP) stock is a Hold with a C$3.00 price target. To see the full list of analyst forecasts on Medexus Pharmaceuticals Inc stock, see the TSE:MDP Stock Forecast page.

Financial Disclosures
Medexus Pharmaceuticals to Discuss Q2 2026 Financial Results
Neutral
Nov 5, 2025

Medexus Pharmaceuticals has announced a conference call scheduled for November 13, 2025, to discuss its second fiscal quarter results ending September 30, 2025. This event is significant for stakeholders as it provides insights into the company’s financial performance and strategic direction, potentially impacting its market position and investor confidence.

The most recent analyst rating on (TSE:MDP) stock is a Hold with a C$3.00 price target. To see the full list of analyst forecasts on Medexus Pharmaceuticals Inc stock, see the TSE:MDP Stock Forecast page.

Executive/Board ChangesShareholder Meetings
Medexus Pharmaceuticals Announces Election of Directors and Auditor Appointment
Positive
Sep 25, 2025

Medexus Pharmaceuticals held its virtual annual meeting of shareholders, where all director nominees were elected, and PricewaterhouseCoopers LLP was appointed as the company’s auditors. The approval of these proposals reflects strong shareholder support, potentially reinforcing Medexus’s strategic direction and stability in the pharmaceutical industry.

The most recent analyst rating on (TSE:MDP) stock is a Hold with a C$3.00 price target. To see the full list of analyst forecasts on Medexus Pharmaceuticals Inc stock, see the TSE:MDP Stock Forecast page.

Medexus Pharmaceuticals Earnings Call: Cautious Optimism Amid Challenges
Sep 1, 2025

The recent earnings call for Medexus Pharmaceuticals was characterized by cautious optimism. The company highlighted several strategic achievements, including the successful launch of GRAFAPEX and improved gross margins. However, these positives were tempered by challenges such as declining revenues and adjusted EBITDA, increased expenses, and concerns about tariffs affecting costs. The overall sentiment was one of cautious optimism, with a focus on future growth driven by GRAFAPEX.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 13, 2025