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Tonix Pharmaceuticals (TNXP)
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Tonix Pharma (TNXP) AI Stock Analysis

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TNXP

Tonix Pharma

(NASDAQ:TNXP)

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Underperform 40 (OpenAI - 4o)
Rating:40Underperform
Price Target:
$17.00
▼(-14.31% Downside)
Tonix Pharma's overall stock score is primarily impacted by its financial performance and valuation challenges. The company faces significant profitability and cash flow issues, which are reflected in its negative P/E ratio. Technical analysis indicates a bearish trend, with the stock trading below key moving averages and approaching oversold conditions. These factors collectively contribute to a low overall stock score.

Tonix Pharma (TNXP) vs. SPDR S&P 500 ETF (SPY)

Tonix Pharma Business Overview & Revenue Model

Company DescriptionTonix Pharmaceuticals Holding Corp. is a clinical-stage biopharmaceutical company focused on developing innovative treatments for central nervous system disorders, immunology, and infectious diseases. The company is engaged in the research, development, and commercialization of novel therapeutics, including vaccines and other biologics that address significant unmet medical needs. Tonix's core products include TNX-102 SL, a sublingual formulation of cyclobenzaprine for fibromyalgia, and a range of vaccine candidates aimed at addressing various infectious diseases.
How the Company Makes MoneyTonix Pharmaceuticals generates revenue primarily through the development and commercialization of its product candidates. The company may receive funding through government grants, collaborations, and partnerships with larger pharmaceutical companies or research institutions. Additionally, Tonix may generate revenue from licensing agreements or royalties if its products are successfully developed and brought to market. The company is actively seeking strategic partnerships to enhance its research capabilities and accelerate the development of its product pipeline, which can contribute to future earnings.

Tonix Pharma Financial Statement Overview

Summary
Tonix Pharma is experiencing revenue growth but continues to face significant profitability and cash flow challenges. The company's low leverage is a positive aspect, but the negative return on equity and cash flow issues highlight ongoing financial struggles. The biotechnology industry often involves high R&D costs, which may contribute to these financial dynamics. Overall, while there are some positive trends, the company needs to address its profitability and cash flow issues to improve its financial health.
Income Statement
35
Negative
Tonix Pharma has shown some revenue growth with a 4.76% increase in the TTM period. However, the company is struggling with profitability, as evidenced by negative net profit margins (-5.41%) and EBIT margins (-8.28%). The gross profit margin is relatively low at 29.27%, indicating challenges in cost management. Overall, while there is some revenue growth, the company faces significant profitability issues.
Balance Sheet
45
Neutral
The balance sheet shows a strong equity position with a low debt-to-equity ratio of 0.0029, indicating minimal leverage. However, the return on equity is negative (-37.82%), reflecting ongoing losses. The equity ratio is not explicitly calculated, but the high stockholders' equity relative to total assets suggests a solid equity base. Despite the strong equity position, the negative ROE highlights profitability challenges.
Cash Flow
40
Negative
Tonix Pharma's cash flow statement reveals a negative operating cash flow, indicating cash burn. The free cash flow growth rate is positive at 16.22%, suggesting some improvement. However, the operating cash flow to net income ratio is negative, and the free cash flow to net income ratio is slightly above 1, indicating that cash flow is not significantly worse than net income. Overall, cash flow remains a concern despite some positive growth.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue10.30M10.09M7.77M0.000.000.00
Gross Profit3.53M2.33M3.03M0.000.00-27.00K
EBITDA-97.31M-74.32M-114.09M-110.84M-92.26M-50.44M
Net Income-99.22M-130.04M-116.66M-110.22M-92.29M-50.46M
Balance Sheet
Total Assets252.44M162.89M154.46M225.69M240.90M98.18M
Cash, Cash Equivalents and Short-Term Investments190.06M98.78M24.95M120.23M178.66M77.07M
Total Debt425.00K5.30M9.81M760.00K956.00K1.31M
Total Liabilities21.30M23.33M48.93M18.51M22.18M10.54M
Stockholders Equity231.14M139.56M105.53M207.18M218.72M87.65M
Cash Flow
Free Cash Flow-78.33M-61.05M-109.90M-146.20M-110.86M-57.13M
Operating Cash Flow-74.82M-60.92M-102.00M-98.05M-75.56M-48.57M
Investing Cash Flow-3.51M-120.00K-29.07M-48.15M-35.31M-8.56M
Financing Cash Flow240.54M134.87M36.52M87.84M212.49M123.11M

Tonix Pharma Technical Analysis

Technical Analysis Sentiment
Negative
Last Price19.84
Price Trends
50DMA
21.36
Negative
100DMA
30.72
Negative
200DMA
26.23
Negative
Market Momentum
MACD
-1.47
Negative
RSI
38.54
Neutral
STOCH
37.63
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TNXP, the sentiment is Negative. The current price of 19.84 is above the 20-day moving average (MA) of 17.80, below the 50-day MA of 21.36, and below the 200-day MA of 26.23, indicating a bearish trend. The MACD of -1.47 indicates Negative momentum. The RSI at 38.54 is Neutral, neither overbought nor oversold. The STOCH value of 37.63 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TNXP.

Tonix Pharma Risk Analysis

Tonix Pharma disclosed 66 risk factors in its most recent earnings report. Tonix Pharma reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Tonix Pharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
62
Neutral
$152.00M27.0512.64%35.42%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$318.98M-174.79%-76.59%94.03%
49
Neutral
$168.85M-271.32%-75.77%-31.24%
41
Neutral
$112.24M-52.35%-46.92%20.26%
40
Underperform
$196.90M-64.99%-8.79%81.36%
36
Underperform
$135.64M-1.37-110.72%77.08%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TNXP
Tonix Pharma
16.72
-3.70
-18.12%
PLX
Protalix
1.77
0.11
6.63%
FATE
Fate Therapeutics
1.05
-1.02
-49.28%
AVTX
Avalo Therapeutics
17.59
7.94
82.28%
FBRX
Forte Biosciences
18.71
3.07
19.63%
IPHA
Innate Pharma
1.79
0.09
5.29%

Tonix Pharma Corporate Events

Tonix Pharmaceuticals Reports Q3 2025 Earnings and Strategic Developments
Nov 11, 2025

Tonix Pharmaceuticals Holding Corp., a commercial-stage biotechnology company, specializes in developing and marketing products for central nervous system disorders, immunology, and infectious diseases. The company is known for its innovative approach in the pharmaceutical industry, focusing on non-opioid treatments and vaccines.

Business Operations and StrategyProduct-Related Announcements
Tonix Pharma Begins FOCUS Study on AVP-D Treatment
Neutral
Oct 22, 2025

On October 22, 2025, Tonix Pharmaceuticals announced that the first patient was dosed in the FOCUS study at Massachusetts General Hospital, targeting adult patients with arginine-vasopressin deficiency (AVP-D). The study is a randomized, double-blind, placebo-controlled crossover pilot designed to evaluate the company’s intranasal potentiated oxytocin products, TNX-2900 and TNX-1900, on markers of anxiety, depression, and socioemotional functioning. This trial aims to generate preliminary data for future studies on oxytocin replacement therapy, potentially impacting the treatment landscape for AVP-D and improving patient quality of life.

The most recent analyst rating on (TNXP) stock is a Hold with a $41.00 price target. To see the full list of analyst forecasts on Tonix Pharma stock, see the TNXP Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Tonix Pharma Plans Phase 2 Trial for 2026
Positive
Oct 7, 2025

Tonix Pharmaceuticals announced plans to initiate a Phase 2 trial of its TNX-102 SL product candidate for major depressive disorder in 2026, and an adaptive Phase 2/3 study of TNX-4800 for the seasonal prevention of Lyme disease in 2027. These developments are part of the company’s strategic efforts to expand its clinical pipeline and strengthen its position in the pharmaceutical market.

The most recent analyst rating on (TNXP) stock is a Hold with a $41.00 price target. To see the full list of analyst forecasts on Tonix Pharma stock, see the TNXP Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Tonix Pharma Appoints New Head of Market Access
Neutral
Sep 30, 2025

On September 30, 2025, Tonix Pharmaceuticals announced the appointment of Ganesh Kamath as Head of Market Access, effective September 29, 2025. The company also established the wholesale acquisition cost for Tonmya™, setting it at $1,860 per month for a 60-count supply for adults, and $930 per month for a 30-count supply for geriatric patients and adults with mild hepatic impairment.

The most recent analyst rating on (TNXP) stock is a Hold with a $41.00 price target. To see the full list of analyst forecasts on Tonix Pharma stock, see the TNXP Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Tonix Pharma Advances TNX-2900 to Phase 2 Trial
Positive
Sep 29, 2025

On September 29, 2025, Tonix Pharmaceuticals announced plans to advance its TNX-2900 program for Prader-Willi syndrome into a Phase 2 clinical trial. The trial will assess the safety, tolerability, and efficacy of TNX-2900 in children aged 8 to 17.5 years, with the study expected to start in 2026. This development marks a significant step in Tonix’s efforts to address rare diseases, potentially enhancing its market position and offering new treatment options for stakeholders.

The most recent analyst rating on (TNXP) stock is a Hold with a $41.00 price target. To see the full list of analyst forecasts on Tonix Pharma stock, see the TNXP Stock Forecast page.

Product-Related AnnouncementsRegulatory Filings and Compliance
Tonix Pharma Completes FDA Meeting for TNX-102 SL
Positive
Sep 18, 2025

On September 18, 2025, Tonix Pharmaceuticals announced the completion of a Type B Pre-IND meeting with the FDA for its TNX-102 SL product candidate aimed at treating major depressive disorder. The FDA’s feedback was positive, suggesting that the proposed long-term safety data collection plan is reasonable, which may streamline the development path. Tonix plans to file an Investigational New Drug application in the fourth quarter of 2025 and expects to enter Phase 2 clinical trials soon after, potentially expanding the therapeutic indications of TNX-102 SL.

The most recent analyst rating on (TNXP) stock is a Hold with a $41.00 price target. To see the full list of analyst forecasts on Tonix Pharma stock, see the TNXP Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Tonix Pharma Licenses Rights to Lyme Disease Antibody
Positive
Sep 17, 2025

On September 17, 2025, Tonix Pharmaceuticals announced the in-licensing of worldwide rights to TNX-4800, a long-acting human monoclonal antibody targeting Lyme disease. Developed by UMass Chan Medical School, TNX-4800 offers a novel approach by providing pre-exposure prophylaxis against Lyme disease with a single subcutaneous administration, bypassing the need for multidose vaccines. This strategic move positions Tonix to advance TNX-4800 through clinical trials, aiming for a Biologics Licensing Application submission to the FDA, potentially impacting the market for Lyme disease prevention.

The most recent analyst rating on (TNXP) stock is a Hold with a $41.00 price target. To see the full list of analyst forecasts on Tonix Pharma stock, see the TNXP Stock Forecast page.

Tonix Pharmaceuticals Reports Q2 2025 Financial Results
Aug 19, 2025

Tonix Pharmaceuticals Holding Corp. is a biotechnology company focused on developing therapies for pain management and vaccines for public health challenges, with a notable emphasis on fibromyalgia treatment. In its latest earnings report for the quarter ending June 30, 2025, Tonix Pharmaceuticals highlighted a significant increase in cash and cash equivalents, totaling $125.3 million, up from $98.8 million at the end of 2024. However, the company reported a net loss of $28.3 million for the quarter, an improvement from the $78.8 million loss in the same period last year. The company’s revenue slightly decreased to $2 million from $2.2 million in the previous year, while operating expenses were reduced significantly, contributing to a smaller operating loss compared to the previous year. Tonix Pharmaceuticals continues to advance its pipeline with TNX-102 SL for fibromyalgia, which has a PDUFA goal date in August 2025, and is progressing with TNX-1500 for organ transplant rejection prevention. Looking ahead, Tonix Pharmaceuticals is focused on securing additional funding to support its operations and research initiatives, as its current cash resources are expected to sustain operations into the third quarter of 2026.

Business Operations and StrategyProduct-Related Announcements
Tonix Pharma Announces FDA Approval of Tonmya
Positive
Aug 18, 2025

On August 18, 2025, Tonix Pharmaceuticals will host a webcast and conference call to discuss the FDA’s approval of Tonmya for fibromyalgia treatment. This approval marks a significant milestone for the company, potentially enhancing its market position and offering new opportunities for growth in the treatment of central nervous system disorders.

The most recent analyst rating on (TNXP) stock is a Buy with a $4.00 price target. To see the full list of analyst forecasts on Tonix Pharma stock, see the TNXP Stock Forecast page.

Product-Related Announcements
Tonix Pharma Gains FDA Approval for Tonmya
Positive
Aug 15, 2025

On August 15, 2025, Tonix Pharmaceuticals announced FDA approval for Tonmya, a treatment for fibromyalgia in adults, with availability expected in the U.S. by the fourth quarter of 2025. The approval was based on successful Phase 3 trials showing significant pain reduction and good tolerability, positioning Tonix as a key player in the fibromyalgia treatment market.

The most recent analyst rating on (TNXP) stock is a Buy with a $4.00 price target. To see the full list of analyst forecasts on Tonix Pharma stock, see the TNXP Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 13, 2025