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Avalo Therapeutics, Inc. (AVTX)
NASDAQ:AVTX
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Avalo Therapeutics (AVTX) AI Stock Analysis

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AVTX

Avalo Therapeutics

(NASDAQ:AVTX)

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Neutral 54 (OpenAI - 5.2)
Rating:54Neutral
Price Target:
$16.50
▲(14.35% Upside)
Action:Reiterated
Date:05/14/26
The score is held back primarily by weak financial performance (minimal revenue, heavy ongoing losses, and sustained cash burn), partially offset by strong technical momentum and supportive corporate developments (positive Phase 2 data and improved funding runway). Valuation metrics provide limited support due to ongoing losses and no dividend.
Positive Factors
Positive Phase 2 data for abdakibart
Robust Phase 2 results materially strengthen Avalo's clinical thesis for abdakibart and indicate potential differentiation in hidradenitis suppurativa. If replicated in registrational studies, this raises the probability of approval, physician adoption, and meaningful long-term franchise value versus peers.
Negative Factors
Persistent negative free cash flow
Sustained negative free cash flow of roughly -$59.7M TTM indicates material burn to fund R&D and operations. Reliance on external financing is structural for a clinical-stage biotech; ongoing burn increases financing frequency risk and can force program prioritization or delays absent durable revenue.
Read all positive and negative factors
Positive Factors
Negative Factors
Positive Phase 2 data for abdakibart
Robust Phase 2 results materially strengthen Avalo's clinical thesis for abdakibart and indicate potential differentiation in hidradenitis suppurativa. If replicated in registrational studies, this raises the probability of approval, physician adoption, and meaningful long-term franchise value versus peers.
Read all positive factors

Avalo Therapeutics (AVTX) vs. SPDR S&P 500 ETF (SPY)

Avalo Therapeutics Business Overview & Revenue Model

Company Description
Avalo Therapeutics, Inc., a clinical-stage precision medicine company, discovers, develops, and commercializes targeted therapeutics for patients with unmet clinical need in immunology, immuno-oncology, and rare genetic diseases. It develops AVTX-...
How the Company Makes Money
As a clinical-stage biotech, Avalo Therapeutics has historically not relied on recurring product sales; detailed, current revenue composition from commercial products is null. In general, companies at this stage fund operations primarily through c...

Avalo Therapeutics Financial Statement Overview

Summary
Financials are weak overall: revenue has collapsed to a minimal level, losses remain large, and operating/free cash flow are deeply negative (TTM FCF about -$59.7M), implying continued dependence on external funding. The main offset is low leverage with zero debt in TTM, which reduces near-term solvency risk but does not fix the underlying burn rate.
Income Statement
8
Very Negative
Balance Sheet
55
Neutral
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue59.00K59.00K441.00K1.92M18.05M5.40M
Gross Profit42.00K59.00K807.00K640.00K14.62M3.91M
EBITDA-90.35M-72.58M-68.34M-23.29M-37.27M-80.48M
Net Income-84.74M-78.26M-35.13M-31.54M-41.66M-84.38M
Balance Sheet
Total Assets99.89M116.46M150.73M20.99M33.37M80.21M
Cash, Cash Equivalents and Short-Term Investments81.99M98.34M134.55M7.42M13.17M54.59M
Total Debt2.33M2.43M568.00K537.00K19.95M33.32M
Total Liabilities31.57M33.41M17.70M13.69M44.28M57.13M
Stockholders Equity68.32M83.05M133.03M7.30M-10.91M23.08M
Cash Flow
Free Cash Flow-59.69M-51.46M-49.06M-30.84M-26.85M-71.00M
Operating Cash Flow-59.69M-51.46M-49.06M-30.68M-26.75M-70.89M
Investing Cash Flow-56.22M-81.72M356.00K-133.00K-95.00K-113.00K
Financing Cash Flow15.99M14.59M175.85M25.04M-14.70M106.76M

Avalo Therapeutics Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price14.43
Price Trends
50DMA
15.61
Positive
100DMA
15.77
Positive
200DMA
15.20
Positive
Market Momentum
MACD
0.09
Positive
RSI
47.23
Neutral
STOCH
16.42
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AVTX, the sentiment is Neutral. The current price of 14.43 is below the 20-day moving average (MA) of 17.49, below the 50-day MA of 15.61, and below the 200-day MA of 15.20, indicating a neutral trend. The MACD of 0.09 indicates Positive momentum. The RSI at 47.23 is Neutral, neither overbought nor oversold. The STOCH value of 16.42 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for AVTX.

Avalo Therapeutics Risk Analysis

Avalo Therapeutics disclosed 80 risk factors in its most recent earnings report. Avalo Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Avalo Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
60
Neutral
$141.55M-1.25-70.89%-37.60%
54
Neutral
$830.01M-97.55%-86.62%-1121.44%
52
Neutral
$136.31M-4573.89%-100.00%18.45%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$179.28M-2.71-339.38%17.64%
46
Neutral
$202.50M-5.18-2748.16%43.68%
45
Neutral
$425.35M-44.84-106.16%63.03%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AVTX
Avalo Therapeutics
15.95
11.95
298.75%
CRBP
Corbus Pharmaceuticals
7.91
0.49
6.60%
FBRX
Forte Biosciences
19.07
10.57
124.35%
MIST
Milestone Pharmaceuticals
1.42
-0.20
-12.35%
ELTX
Elicio Therapeutics
11.44
4.21
58.23%
GUTS
Fractyl Health, Inc.
0.81
-1.09
-57.58%

Avalo Therapeutics Corporate Events

Business Operations and StrategyPrivate Placements and Financing
Avalo Therapeutics Announces Major Equity and Warrant Offering
Positive
May 7, 2026
On May 5, 2026, Avalo Therapeutics entered into an underwriting agreement to sell 19,730,000 shares of common stock and 1,400,000 pre-funded warrants at roughly $17.75 per unit, with underwriters exercising in full a 3,169,500-share option on May ...
Business Operations and StrategyProduct-Related Announcements
Avalo Therapeutics Reports Strong Phase 2 Hidradenitis Data
Positive
May 5, 2026
On May 5, 2026, Avalo Therapeutics reported positive topline Phase 2 results from its LOTUS trial of abdakibart in adults with moderate to severe hidradenitis suppurativa, with both dosing regimens achieving HiSCR75 response rates of about 42% at ...
Business Operations and Strategy
Avalo Therapeutics Restructures AlmataBio Milestone Payment Obligations
Positive
Apr 28, 2026
On April 26, 2026, Avalo Therapeutics entered into a Milestone Buyout Option and Amendment Agreement tied to its March 2024 acquisition of AlmataBio, Inc. The deal restructures a previously agreed $15 million contingent milestone payment that was ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 14, 2026