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Avalo Therapeutics (AVTX)
NASDAQ:AVTX
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Avalo Therapeutics (AVTX) AI Stock Analysis

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AVTX

Avalo Therapeutics

(NASDAQ:AVTX)

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Neutral 47 (OpenAI - 5.2)
Rating:47Neutral
Price Target:
$14.00
▼(-2.98% Downside)
Action:ReiteratedDate:04/28/26
The score is primarily held down by very weak financial performance (minimal/declining revenue, large losses, and heavy ongoing cash burn). Technicals are neutral-to-bearish with negative MACD and price below key short/intermediate moving averages. A positive offset is the cleaner balance sheet (little-to-no debt) and a recent corporate action that improves flexibility around milestone cash outflows, but these do not fully counter the core profitability and cash-flow risks.
Positive Factors
Improved Balance Sheet / Low Debt
Elimination of debt and positive equity provide durable financial flexibility for a clinical-stage biotech. With low leverage the company can fund near-term development via equity or partnerships with less bankruptcy risk, improving negotiating power on collaborations and milestone terms.
Negative Factors
High Cash Burn / Negative Free Cash Flow
Sustained negative operating and free cash flow of ~-$51M annually is a structural weakness for a non-revenue biotech. Continued burn forces reliance on external financing or partnerships, diluting existing shareholders or narrowing strategic options if capital markets tighten over the next 2–6 months.
Read all positive and negative factors
Positive Factors
Negative Factors
Improved Balance Sheet / Low Debt
Elimination of debt and positive equity provide durable financial flexibility for a clinical-stage biotech. With low leverage the company can fund near-term development via equity or partnerships with less bankruptcy risk, improving negotiating power on collaborations and milestone terms.
Read all positive factors

Avalo Therapeutics (AVTX) vs. SPDR S&P 500 ETF (SPY)

Avalo Therapeutics Business Overview & Revenue Model

Company Description
Avalo Therapeutics, Inc., a clinical-stage precision medicine company, discovers, develops, and commercializes targeted therapeutics for patients with unmet clinical need in immunology, immuno-oncology, and rare genetic diseases. It develops AVTX-...
How the Company Makes Money
As a clinical-stage biotech, Avalo Therapeutics has historically not relied on recurring product sales; detailed, current revenue composition from commercial products is null. In general, companies at this stage fund operations primarily through c...

Avalo Therapeutics Financial Statement Overview

Summary
Overall financials are weak: revenue is minimal and declining (~$59K in 2025) with very large operating and net losses (EBIT about -$73M; net loss about -$78M) and sustained cash burn (FCF about -$51M in 2025). The main offset is an improved capital structure with effectively no debt and positive equity in 2024–2025, but ongoing losses still pressure durability.
Income Statement
12
Very Negative
Balance Sheet
58
Neutral
Cash Flow
18
Very Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue59.00K441.00K1.92M18.05M5.40M
Gross Profit-285.00K807.00K640.00K14.62M3.91M
EBITDA-72.92M-68.34M-23.29M-37.27M-80.48M
Net Income-78.26M-35.13M-31.54M-41.66M-84.38M
Balance Sheet
Total Assets116.46M150.73M20.99M33.37M80.21M
Cash, Cash Equivalents and Short-Term Investments98.34M134.55M7.42M13.17M54.59M
Total Debt2.43M568.00K537.00K19.95M33.32M
Total Liabilities33.41M17.70M13.69M44.28M57.13M
Stockholders Equity83.05M133.03M7.30M-10.91M23.08M
Cash Flow
Free Cash Flow-51.46M-49.06M-30.84M-26.85M-71.00M
Operating Cash Flow-51.46M-49.06M-30.68M-26.75M-70.89M
Investing Cash Flow-81.72M356.00K-133.00K-95.00K-113.00K
Financing Cash Flow14.59M175.85M25.04M-14.70M106.76M

Avalo Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price14.43
Price Trends
50DMA
15.32
Negative
100DMA
16.29
Negative
200DMA
13.79
Positive
Market Momentum
MACD
-0.41
Positive
RSI
47.41
Neutral
STOCH
21.37
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AVTX, the sentiment is Positive. The current price of 14.43 is below the 20-day moving average (MA) of 14.47, below the 50-day MA of 15.32, and above the 200-day MA of 13.79, indicating a neutral trend. The MACD of -0.41 indicates Positive momentum. The RSI at 47.41 is Neutral, neither overbought nor oversold. The STOCH value of 21.37 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for AVTX.

Avalo Therapeutics Risk Analysis

Avalo Therapeutics disclosed 64 risk factors in its most recent earnings report. Avalo Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Avalo Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$182.69M-1.32-65.76%-63.15%
53
Neutral
$110.94M-1.189999.00%-100.00%-40.01%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$220.04M-2.69-656.82%-10.20%
50
Neutral
$201.08M-3.95-977.67%42.43%
48
Neutral
$552.40M-40.48-110.72%68.18%
47
Neutral
$366.25M-3.11-77.91%-86.62%95.62%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AVTX
Avalo Therapeutics
13.78
8.76
174.50%
CRBP
Corbus Pharmaceuticals
10.52
3.10
41.78%
FBRX
Forte Biosciences
28.51
21.85
328.08%
MIST
Milestone Pharmaceuticals
1.90
0.57
42.48%
ELTX
Elicio Therapeutics
10.77
5.36
99.08%
GUTS
Fractyl Health, Inc.
0.73
-0.90
-55.40%

Avalo Therapeutics Corporate Events

Business Operations and Strategy
Avalo Therapeutics Restructures AlmataBio Milestone Payment Obligations
Positive
Apr 28, 2026
On April 26, 2026, Avalo Therapeutics entered into a Milestone Buyout Option and Amendment Agreement tied to its March 2024 acquisition of AlmataBio, Inc. The deal restructures a previously agreed $15 million contingent milestone payment that was ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 28, 2026