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Avalo Therapeutics (AVTX)
NASDAQ:AVTX

Avalo Therapeutics (AVTX) AI Stock Analysis

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AVTX

Avalo Therapeutics

(NASDAQ:AVTX)

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Neutral 47 (OpenAI - 5.2)
Rating:47Neutral
Price Target:
$14.00
▲(2.49% Upside)
Action:ReiteratedDate:04/09/26
The score is primarily held back by very weak financial performance (minimal/declining revenue, large losses, and significant cash burn). Technical signals also lean bearish with the stock below key moving averages and a negative MACD. A positive offset comes from a notable pipeline milestone (Phase 2 enrollment complete with Q2 2026 data), but it does not fully counterbalance the current financial and momentum risks.
Positive Factors
Pipeline Progress
Completing Phase 2 enrollment materially reduces development execution risk and provides a clear near-term clinical readout that can validate AVTX-009’s biology. A positive or informative topline can unlock partnering options, de-risk later-stage investment decisions and guide next-stage resource allocation.
Negative Factors
High Cash Burn
Sustained negative operating and free cash flow at ~-$51M annually consumes liquidity and forces recurring funding decisions. Persistent burn pressures strategic flexibility, increases dependency on equity markets or partnerships, and can dilute existing shareholders or delay programs if financing terms are unfavorable.
Read all positive and negative factors
Positive Factors
Negative Factors
Pipeline Progress
Completing Phase 2 enrollment materially reduces development execution risk and provides a clear near-term clinical readout that can validate AVTX-009’s biology. A positive or informative topline can unlock partnering options, de-risk later-stage investment decisions and guide next-stage resource allocation.
Read all positive factors

Avalo Therapeutics (AVTX) vs. SPDR S&P 500 ETF (SPY)

Avalo Therapeutics Business Overview & Revenue Model

Company Description
Avalo Therapeutics, Inc., a clinical-stage precision medicine company, discovers, develops, and commercializes targeted therapeutics for patients with unmet clinical need in immunology, immuno-oncology, and rare genetic diseases. It develops AVTX-...
How the Company Makes Money
As a clinical-stage biotech, Avalo Therapeutics has historically not relied on recurring product sales; detailed, current revenue composition from commercial products is null. In general, companies at this stage fund operations primarily through c...

Avalo Therapeutics Financial Statement Overview

Summary
Financial profile is weak: revenue is minimal and declining (~$59K in 2025, down ~69%), losses are large (EBIT about -$73M; net loss about -$78M), and cash burn is heavy with negative operating/free cash flow (about -$51M in 2025). A key offset is improved leverage with effectively no debt in 2025 and positive equity, but ongoing losses and burn remain the dominant risk.
Income Statement
12
Very Negative
Balance Sheet
58
Neutral
Cash Flow
18
Very Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue59.00K441.00K1.92M18.05M5.40M
Gross Profit-285.00K807.00K640.00K14.62M3.91M
EBITDA-72.92M-68.34M-23.29M-37.27M-80.48M
Net Income-78.26M-35.13M-31.54M-41.66M-84.38M
Balance Sheet
Total Assets116.46M150.73M20.99M33.37M80.21M
Cash, Cash Equivalents and Short-Term Investments98.34M134.55M7.42M13.17M54.59M
Total Debt2.43M568.00K537.00K19.95M33.32M
Total Liabilities33.41M17.70M13.69M44.28M57.13M
Stockholders Equity83.05M133.03M7.30M-10.91M23.08M
Cash Flow
Free Cash Flow-51.46M-49.06M-30.84M-26.85M-71.00M
Operating Cash Flow-51.46M-49.06M-30.68M-26.75M-70.89M
Investing Cash Flow-81.72M356.00K-133.00K-95.00K-113.00K
Financing Cash Flow14.59M175.85M25.04M-14.70M106.76M

Avalo Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price13.66
Price Trends
50DMA
15.45
Negative
100DMA
16.45
Negative
200DMA
13.56
Positive
Market Momentum
MACD
-0.28
Positive
RSI
40.56
Neutral
STOCH
13.59
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AVTX, the sentiment is Negative. The current price of 13.66 is below the 20-day moving average (MA) of 14.80, below the 50-day MA of 15.45, and above the 200-day MA of 13.56, indicating a neutral trend. The MACD of -0.28 indicates Positive momentum. The RSI at 40.56 is Neutral, neither overbought nor oversold. The STOCH value of 13.59 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AVTX.

Avalo Therapeutics Risk Analysis

Avalo Therapeutics disclosed 64 risk factors in its most recent earnings report. Avalo Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Avalo Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
58
Neutral
$173.82M-1.38-65.76%-17.43%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$237.69M-2.69-656.82%3.70%
50
Neutral
$186.72M-3.95-977.67%17.36%
48
Neutral
$487.25M-40.48-110.72%77.08%
47
Neutral
$311.29M-3.11-77.91%-76.59%94.03%
46
Neutral
$72.98M9999.00%-96.91%63.11%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AVTX
Avalo Therapeutics
13.66
8.28
153.90%
CRBP
Corbus Pharmaceuticals
9.80
4.00
68.97%
FBRX
Forte Biosciences
35.09
29.50
527.73%
MIST
Milestone Pharmaceuticals
2.02
1.19
143.37%
ELTX
Elicio Therapeutics
10.15
5.23
106.30%
GUTS
Fractyl Health, Inc.
0.46
-0.53
-53.54%

Avalo Therapeutics Corporate Events

Business Operations and StrategyProduct-Related Announcements
Avalo Therapeutics Highlights AVTX-009 Progress in HS
Positive
Jan 12, 2026
Avalo Therapeutics has released an updated investor presentation in January 2026 detailing progress on AVTX-009, its lead anti-IL-1β monoclonal antibody candidate, which it is positioning as a potential best-in-class and best-in-disease thera...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 09, 2026