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Spyre Therapeutics (SYRE)
NASDAQ:SYRE
US Market
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Spyre Therapeutics (SYRE) Stock Statistics & Valuation Metrics

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Total Valuation

Spyre Therapeutics has a market cap or net worth of $1.02B. The enterprise value is $382.05M.
Market Cap$1.02B
Enterprise Value$382.05M

Share Statistics

Spyre Therapeutics has 60,400,960 shares outstanding. The number of shares has decreased by -2.65% in one year.
Shares Outstanding60,400,960
Owned by Insiders9.65%
Owned by Institutions0.06%

Financial Efficiency

Spyre Therapeutics’s return on equity (ROE) is -0.40 and return on invested capital (ROIC) is -37.63%.
Return on Equity (ROE)-0.40
Return on Assets (ROA)-0.34
Return on Invested Capital (ROIC)-37.63%
Return on Capital Employed (ROCE)-0.38
Revenue Per Employee0.00
Profits Per Employee-2.85M
Employee Count73
Asset Turnover0.00
Inventory Turnover0.00

Valuation Ratios

The current PE Ratio of Spyre Therapeutics is 2.3. Spyre Therapeutics’s PEG ratio is ―.
PE Ratio2.3
PS Ratio
PB Ratio
Price to Fair Value2.11
Price to FCF
Price to Operating Cash Flow-6.85
PEG Ratio

Income Statement

In the last 12 months, Spyre Therapeutics had revenue of 0.00 and earned -208.02M in profits. Earnings per share was -0.56.
Revenue0.00
Gross Profit0.00
Operating Income-208.57M
Pretax Income-207.97M
Net Income-208.02M
EBITDA-207.97M
Earnings Per Share (EPS)-0.56

Cash Flow

In the last 12 months, operating cash flow was -154.18M and capital expenditures 0.00, giving a free cash flow of -154.18M billion.
Operating Cash Flow-154.18M
Free Cash Flow-154.18M
Free Cash Flow per Share-2.55

Dividends & Yields

Spyre Therapeutics pays an annual dividend of ―, resulting in a dividend yield of ―
Dividend Per Share
Dividend Yield
Payout RatioN/A
Free Cash Flow Yield
Earnings Yield

Stock Price Statistics

Beta1.80
52-Week Price Change-39.14%
50-Day Moving Average16.31
200-Day Moving Average20.10
Relative Strength Index (RSI)53.78
Average Volume (3m)511.30K

Important Dates

Spyre Therapeutics upcoming earnings date is Nov 6, 2025, TBA (Confirmed).
Last Earnings DateAug 5, 2025
Next Earnings DateNov 6, 2025
Ex-Dividend Date

Financial Position

Spyre Therapeutics as a current ratio of 11.26, with Debt / Equity ratio of 0.00%
Current Ratio11.26
Quick Ratio11.26
Debt to Market Cap0.00
Net Debt to EBITDA0.43
Interest Coverage Ratio0.00

Taxes

In the past 12 months, Spyre Therapeutics has paid 51.00K in taxes.
Income Tax51.00K
Effective Tax Rate>-0.01

Enterprise Valuation

Spyre Therapeutics EV to EBITDA ratio is -4.83, with an EV/FCF ratio of -6.39.
EV to Sales0.00
EV to EBITDA-4.83
EV to Free Cash Flow-6.39
EV to Operating Cash Flow-6.39

Balance Sheet

Spyre Therapeutics has $526.58M in cash and marketable securities with $0.00 in debt, giving a net cash position of -$526.58M billion.
Cash & Marketable Securities$526.58M
Total Debt$0.00
Net Cash-$526.58M
Net Cash Per Share-$8.72
Tangible Book Value Per Share$11.01

Margins

Gross margin is 0.00%, with operating margin of 0.00%, and net profit margin of 0.00%.
Gross Margin0.00%
Operating Margin0.00%
Pretax Margin0.00%
Net Profit Margin0.00%
EBITDA Margin0.00%
EBIT Margin0.00%

Analyst Forecast

The average price target for Spyre Therapeutics is $55.20, which is 11.43% higher than the current price. The consensus rating is Strong Buy
Price Target$55.20
Price Target Upside225.66% Upside
Analyst ConsensusStrong Buy
Analyst Count8
Revenue Growth Forecast
EPS Growth Forecast-429.68%

Scores

Smart Score3
AI Score43
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