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Spyre Therapeutics (SYRE)
NASDAQ:SYRE
Spy002-072
Psoriatic Arthritis, Rheumatoid Arthritis, Rheumatic Diseases, Axial Spondyloarthritis, Rheumatic Joint Disease, Psa (Psoriatic Arthritis), Axspa, Rheumatologic Disease
Phase II
Recruiting
A Study of SPY072 in Rheumatic Disease
Aug 21, 2025
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Spy001, Spy002, Spy003
Colitis, Ulcerative, Ulcerative Colitis, Inflammatory Bowel Diseases, Colitis
Phase II
Recruiting
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
May 27, 2025
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Spy003-207
Healthy
Phase I
Recruiting
SPY003-207 in Healthy Volunteers
Mar 07, 2025
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Spy002-091
Healthy
Phase I
Recruiting
A Study of SPY002-091 in Healthy Volunteers
Nov 01, 2024
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Spy002-072
Healthy
Phase I
Recruiting
A Study of SPY002-072 in Healthy Volunteers
Sep 30, 2024
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Spy001-001
Healthy
Phase I
Active Not Recruiting
A Study of SPY001-001 in Healthy Volunteers
Jun 03, 2024
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Pegzilarginase
Arginase I Deficiency, Hyperargininemia
Phase III
Completed
Efficacy and Safety of Pegzilarginase in Patients With Arginase 1 Deficiency
Apr 09, 2019
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Spyre Therapeutics (SYRE) have in its pipeline
SYRE is currently developing the following drugs: Spy002-072, Spy001, Spy002, Spy003, Spy003-207. These drug candidates are in various stages of clinical development as the company works toward FDA approval.