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Spyre Therapeutics (SYRE)
NASDAQ:SYRE
US Market
SYRE
Spyre Therapeutics
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Spyre Therapeutics (SYRE) Income Statement

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Spyre Therapeutics Income Statement

Last quarter (Q4 2025), Spyre Therapeutics's total revenue was $90.49M, an increase of Infinity% from the same quarter last year. In Q4, Spyre Therapeutics's net income was $-62.53M. See Spyre Therapeutics’s key income statements, including revenue, expenses, profit, and income.
Income Statement
Dec 25Dec 24Dec 23Dec 22Dec 21
Total Revenue
$ 0.00$ 0.00$ 886.00K$ 2.33M$ 18.74M
Gross Profit
$ -171.65M$ 0.00$ 886.00K$ 2.33M$ 18.74M
Operating Expenses
$ 37.91M$ 208.57M$ 243.19M$ 87.11M$ 84.39M
Depreciation and Amortization
$ 10.00M$ 0.00$ 964.00K$ 1.96M$ 1.58M
EBITDA
$ -209.56M$ -207.97M$ -127.60M$ -82.82M$ -64.07M
Operating Income
$ -209.56M$ -208.57M$ -242.30M$ -84.78M$ -65.65M
Other Income/Expenses
$ 54.34M$ 599.00K$ -96.51M$ 830.00K$ -11.00K
Pretax Income
$ -155.22M$ -207.97M$ -338.82M$ -83.95M$ -65.66M
Net Income
$ -155.20M$ -208.02M$ -338.79M$ -83.81M$ -65.80M
Per Share Metrics
Basic EPS
$ -1.98$ -3.18$ -46.15$ -24.86$ -25.02
Diluted EPS
$ -1.98$ -3.18$ -46.15$ -24.86$ -25.02
Weighted Average Shares Outstanding
 346.05M 47.03M 6.90M 3.37M 2.63M
Weighted Average Shares Outstanding (Diluted)
 346.05M 47.03M 6.90M 3.37M 2.63M
Currency in USD

Spyre Therapeutics Earnings and Revenue History