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Sutro Biopharma Inc (STRO)
NASDAQ:STRO
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Sutro Biopharma (STRO) AI Stock Analysis

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STRO

Sutro Biopharma

(NASDAQ:STRO)

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Neutral 48 (OpenAI - 5.2)
Rating:48Neutral
Price Target:
$33.00
▲(4.60% Upside)
Action:Reiterated
Date:06/30/26
STRO scores below average primarily due to weak financial fundamentals: persistent large losses, substantial cash burn, and negative equity increase funding/solvency risk. Technicals provide partial support as the stock trades above key moving averages, but momentum is only neutral. Valuation adds little support because the company is loss-making (negative P/E) and no dividend yield is provided.
Positive Factors
Proprietary cell-free protein synthesis platform
A proprietary cell-free platform (XpressCF) is a durable competitive advantage: it accelerates protein engineering, reduces development cycle times, and can be licensed to partners. This supports recurring collaboration revenue and sticky technical differentiation over years.
Negative Factors
Severe cash burn and negative operating cash flow
Sustained large negative operating and free cash flows create ongoing financing needs. Over a 2-6 month horizon this raises dilution or financing risk, constrains R&D flexibility, and forces management to prioritize near-term partner financing or capital markets access over long-term program choices.
Read all positive and negative factors
Positive Factors
Negative Factors
Proprietary cell-free protein synthesis platform
A proprietary cell-free platform (XpressCF) is a durable competitive advantage: it accelerates protein engineering, reduces development cycle times, and can be licensed to partners. This supports recurring collaboration revenue and sticky technical differentiation over years.
Read all positive factors

Sutro Biopharma (STRO) vs. SPDR S&P 500 ETF (SPY)

Sutro Biopharma Business Overview & Revenue Model

Company Description
Sutro Biopharma, Inc. is a clinical-stage biotechnology company focused on the discovery, development, and manufacturing of innovative therapeutic products. Its primary objective is to create protein-based treatments for challenging conditions lik...
How the Company Makes Money
Sutro primarily generates revenue through collaboration and licensing arrangements rather than product sales, because it is a clinical-stage company and does not have null. Key revenue streams generally include (1) upfront payments received when e...

Sutro Biopharma Financial Statement Overview

Summary
Despite very strong gross margins (~98% TTM) and modest absolute debt (~$13.6M), financial risk is elevated due to deeply negative profitability (net margin ~-186%), sharply negative operating/free cash flow (~-$151.6M/~-$152.1M TTM) indicating heavy cash burn, and a materially weakened balance sheet with stockholders’ equity turning negative (~-$66.9M TTM). Revenue volatility and a sharp TTM contraction further pressure overall quality.
Income Statement
23
Negative
Balance Sheet
31
Negative
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue99.61M102.48M62.04M153.73M67.77M61.88M
Gross Profit98.33M95.16M54.83M146.91M59.48M52.11M
EBITDA-106.12M-145.65M-180.45M-67.92M-105.07M-97.56M
Net Income-153.60M-191.09M-227.46M-106.79M-119.20M-105.54M
Balance Sheet
Total Assets241.99M173.83M387.21M470.74M406.94M341.41M
Cash, Cash Equivalents and Short-Term Investments202.56M141.43M316.89M375.62M334.36M197.94M
Total Debt13.63M15.67M23.15M33.63M55.02M57.37M
Total Liabilities308.88M306.28M342.61M321.09M189.90M88.84M
Stockholders Equity-66.89M-132.45M44.60M149.65M217.05M252.56M
Cash Flow
Free Cash Flow-152.14M-178.93M-194.64M-115.93M-4.31M-97.00M
Operating Cash Flow-151.61M-177.23M-191.54M-111.62M3.55M-81.68M
Investing Cash Flow16.01M45.01M218.51M-3.92M-35.02M-97.31M
Financing Cash Flow103.05M44.00K94.05M137.55M48.31M3.26M

Sutro Biopharma Technical Analysis

Technical Analysis Sentiment
Positive
Last Price31.55
Price Trends
50DMA
32.19
Positive
100DMA
27.20
Positive
200DMA
18.78
Positive
Market Momentum
MACD
-0.21
Negative
RSI
52.63
Neutral
STOCH
56.09
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For STRO, the sentiment is Positive. The current price of 31.55 is above the 20-day moving average (MA) of 28.64, below the 50-day MA of 32.19, and above the 200-day MA of 18.78, indicating a bullish trend. The MACD of -0.21 indicates Negative momentum. The RSI at 52.63 is Neutral, neither overbought nor oversold. The STOCH value of 56.09 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for STRO.

Sutro Biopharma Risk Analysis

Sutro Biopharma disclosed 78 risk factors in its most recent earnings report. Sutro Biopharma reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Sutro Biopharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
$41.93M-0.95-136.08%-77.56%-50.38%
54
Neutral
$43.33M-0.96-170.86%-100.00%13.12%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$550.14M-0.11275.30%49.94%44.76%
47
Neutral
$80.77M-0.58-80.35%27.27%
42
Neutral
$17.49M-0.30-208.23%-100.00%26.30%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
STRO
Sutro Biopharma
33.20
26.40
388.24%
CRVO
CervoMed
3.10
-2.83
-47.72%
ACET
Adicet Bio
8.64
-1.14
-11.63%
INMB
Inmune Bio
1.63
-0.46
-22.01%
HOWL
Werewolf Therapeutics
0.36
-0.69
-65.81%

Sutro Biopharma Corporate Events

Executive/Board ChangesShareholder Meetings
Sutro Biopharma Shareholders Back Board, Pay and Auditor
Positive
Jun 8, 2026
On June 5, 2026, Sutro Biopharma held its 2026 Annual Meeting of Stockholders, where shareholders elected three Class II directors, Jane Chung, Connie Matsui, and James Panek, each to serve a three-year term ending at the 2029 Annual Meeting. The ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 30, 2026