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Sutro Biopharma Inc (STRO)
NASDAQ:STRO
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Sutro Biopharma (STRO) AI Stock Analysis

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STRO

Sutro Biopharma

(NASDAQ:STRO)

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Neutral 51 (OpenAI - 5.2)
Rating:51Neutral
Price Target:
$34.00
▲(7.77% Upside)
Action:ReiteratedDate:04/15/26
The score is held down primarily by weak financial performance (ongoing losses, cash burn, and negative equity). Technicals are a relative positive with strong upward trend, but momentum appears stretched. Valuation provides little support due to negative earnings (negative P/E) and no dividend yield data.
Positive Factors
Proprietary protein synthesis platform
Sutro’s cell-free XpressCF platform is a durable technical moat: it speeds protein design, enables precise payload conjugation and supports novel ADC formats. That capability reduces development cycle time, lowers technical risk for partners, and underpins sustained R&D productivity and deal interest over quarters.
Negative Factors
Negative stockholders' equity
Negative equity reflects cumulative losses that have eroded the balance-sheet cushion, increasing dependence on external capital. This structural weakness limits borrowing capacity, raises counterparty concerns, and makes future financing likelier to be dilutive or costly, affecting long-term flexibility.
Read all positive and negative factors
Positive Factors
Negative Factors
Proprietary protein synthesis platform
Sutro’s cell-free XpressCF platform is a durable technical moat: it speeds protein design, enables precise payload conjugation and supports novel ADC formats. That capability reduces development cycle time, lowers technical risk for partners, and underpins sustained R&D productivity and deal interest over quarters.
Read all positive factors

Sutro Biopharma (STRO) vs. SPDR S&P 500 ETF (SPY)

Sutro Biopharma Business Overview & Revenue Model

Company Description
Sutro Biopharma, Inc. operates as clinical stage drug discovery, development, and manufacturing company. It focuses on creating protein therapeutics for cancer and autoimmune disorders through integrated cell-free protein synthesis and site-specif...
How the Company Makes Money
Sutro primarily generates revenue through collaboration and licensing arrangements rather than product sales, because it is a clinical-stage company and does not have null. Key revenue streams generally include (1) upfront payments received when e...

Sutro Biopharma Financial Statement Overview

Summary
Financials remain high-risk: volatile and recently weakening revenue, sustained large losses, and consistently negative free cash flow. The balance sheet deteriorated notably with stockholders’ equity turning negative in 2025 and assets declining, indicating reduced financial flexibility despite relatively low absolute debt.
Income Statement
18
Very Negative
Balance Sheet
35
Negative
Cash Flow
22
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue102.48M62.04M153.73M67.77M61.88M
Gross Profit95.16M54.83M146.91M59.48M52.11M
EBITDA-97.63M-180.45M-67.92M-105.07M-97.56M
Net Income-191.09M-227.46M-106.79M-119.20M-105.54M
Balance Sheet
Total Assets173.83M387.21M470.74M406.94M341.41M
Cash, Cash Equivalents and Short-Term Investments141.43M316.89M375.62M334.36M197.94M
Total Debt15.67M23.15M33.63M55.02M57.37M
Total Liabilities306.28M342.61M321.09M189.90M88.84M
Stockholders Equity-132.45M44.60M149.65M217.05M252.56M
Cash Flow
Free Cash Flow-178.93M-194.64M-115.93M-4.31M-97.00M
Operating Cash Flow-177.23M-191.54M-111.62M3.55M-81.68M
Investing Cash Flow45.01M218.51M-3.92M-35.02M-97.31M
Financing Cash Flow44.00K94.05M137.55M48.31M3.26M

Sutro Biopharma Technical Analysis

Technical Analysis Sentiment
Positive
Last Price31.55
Price Trends
50DMA
22.22
Positive
100DMA
16.83
Positive
200DMA
12.86
Positive
Market Momentum
MACD
2.15
Negative
RSI
75.09
Negative
STOCH
87.38
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For STRO, the sentiment is Positive. The current price of 31.55 is above the 20-day moving average (MA) of 25.55, above the 50-day MA of 22.22, and above the 200-day MA of 12.86, indicating a bullish trend. The MACD of 2.15 indicates Negative momentum. The RSI at 75.09 is Negative, neither overbought nor oversold. The STOCH value of 87.38 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for STRO.

Sutro Biopharma Risk Analysis

Sutro Biopharma disclosed 78 risk factors in its most recent earnings report. Sutro Biopharma reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Sutro Biopharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$36.95M-0.90-171.01%257.14%9.63%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$552.19M-0.53275.30%65.18%24.78%
48
Neutral
$75.81M-0.50-82.96%15.32%
44
Neutral
$35.92M-2.65-96.04%-58.86%-47.17%
44
Neutral
$39.51M-0.48-158.81%-100.00%17.96%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
STRO
Sutro Biopharma
34.69
25.94
296.59%
CRVO
CervoMed
3.71
-5.67
-60.45%
ACET
Adicet Bio
7.67
-2.29
-22.95%
INMB
Inmune Bio
1.40
-6.45
-82.17%
HOWL
Werewolf Therapeutics
0.74
-0.10
-11.90%

Sutro Biopharma Corporate Events

Business Operations and StrategyFinancial DisclosuresPrivate Placements and Financing
Sutro Biopharma Ends ATM Agreement After 2025 Results
Positive
Mar 23, 2026
On March 23, 2026, Sutro Biopharma reported full-year 2025 results and announced the mutual termination of its at-the-market equity sales agreement with Jefferies, closing a potential source of incremental share issuance. The company highlighted p...
Business Operations and StrategyPrivate Placements and Financing
Sutro Biopharma Highlights ADC Platform in New Presentation
Positive
Feb 10, 2026
On February 9, 2026, Sutro Biopharma entered an underwriting agreement with Leerink Partners and TD Securities to sell 7,868,383 shares of common stock at $13.98 per share, a public offering expected to generate about $110 million in gross proceed...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 15, 2026