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SynAct Pharma AB (SE:SYNACT)
:SYNACT

SynAct Pharma AB (SYNACT) AI Stock Analysis

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SE:SYNACT

SynAct Pharma AB

(SYNACT)

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Neutral 56 (OpenAI - 5.2)
Rating:56Neutral
Price Target:
kr23.50
▼(-1.26% Downside)
The score is primarily constrained by weak financial performance (no revenue, ongoing losses, and negative free cash flow), partially offset by a low-leverage balance sheet and improving loss/cash-burn trends. Technicals are supportive with price above major moving averages and positive MACD, while valuation remains difficult to justify due to negative earnings and no dividend support.
Positive Factors
Leadership Confidence
The lock-up agreement by leadership signals strong confidence in SynAct's strategy and commitment to long-term value creation, which can enhance investor trust and stability.
Pipeline Progress
Advancement in clinical trials for Resomelagon indicates potential for successful treatment options in rheumatoid arthritis, strengthening SynAct's market position in the biotech industry.
Balance Sheet Strength
A low-leverage balance sheet offers SynAct financial flexibility, reducing risk and enabling strategic investments in R&D and potential partnerships.
Negative Factors
No Revenue Generation
The absence of revenue generation highlights SynAct's reliance on external funding, posing a risk to financial sustainability until successful commercialization of its products.
Negative Cash Flow
Persistent negative cash flow indicates ongoing financial strain, necessitating external funding and potentially limiting SynAct's operational flexibility.
Ongoing Losses
Sustained operating losses reflect challenges in achieving profitability, impacting SynAct's ability to reinvest in growth and innovation without external capital.

SynAct Pharma AB (SYNACT) vs. iShares MSCI Sweden ETF (EWD)

SynAct Pharma AB Business Overview & Revenue Model

Company DescriptionSynAct Pharma AB, through its subsidiary, SynAct Pharma ApS, develops medicines for acute deterioration in inflammatory diseases. The company is developing AP1189, a drug candidate for the treatment of rheumatoid arthritis and idiopathic membranous glomerulonephritis. It has a partnership with the University Of Örebro to study the reduction of inflammation in vascular disease. The company was founded in 2012 and is headquartered in Lund, Sweden.
How the Company Makes MoneySynAct Pharma makes money primarily through the development and eventual commercialization of its pharmaceutical products. Revenue streams are expected to include licensing agreements, partnerships with larger pharmaceutical companies, and sales of its developed drugs upon regulatory approval. The company may also receive milestone payments and royalties from its partnerships. As typical in the biotech sector, SynAct Pharma may also rely on funding from investors and grants to support ongoing research and development activities until its products reach the market.

SynAct Pharma AB Financial Statement Overview

Summary
SynAct Pharma AB is in a pre-revenue stage, typical for biotech firms focused on R&D. The company maintains a strong equity position with minimal debt, which is positive. However, ongoing losses and reliance on external funding underscore financial risks, highlighting the need for future revenue generation to ensure long-term sustainability.
Income Statement
SynAct Pharma AB has consistently reported zero revenue over the years, indicating the company's pre-revenue stage typical of many biotech firms focused on R&D. The net income remains deeply negative, highlighting substantial losses due to ongoing operational expenses, with no revenue offset. The absence of gross profit and continuous negative EBIT and EBITDA margins reflect the company's current focus on development rather than profitability.
Balance Sheet
The company's balance sheet shows a strong equity position with low debt levels, evidenced by a low Debt-to-Equity ratio. However, the Return on Equity is negative due to persistent losses. The Equity Ratio is healthy, indicating reliance on shareholder equity rather than debt for funding. These factors suggest financial stability but also highlight the need for eventual revenue generation.
Cash Flow
SynAct Pharma AB's cash flow statements reveal consistent negative operating and free cash flows, typical for a biotech company investing heavily in R&D. There is no free cash flow growth due to ongoing losses. The company's financing cash flow is positive, indicating reliance on external funding to maintain operations, which poses a risk if fundraising becomes challenging in the future.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit0.00-617.00K-778.00K-1.06M-88.00K0.00
EBITDA-103.55M-15.40M-222.70M-105.71M-76.62M-30.90M
Net Income-91.07M-82.40M-215.81M-99.20M-69.30M-26.55M
Balance Sheet
Total Assets243.59M270.52M228.02M142.60M38.37M21.59M
Cash, Cash Equivalents and Short-Term Investments68.89M61.21M62.40M108.25M24.00M14.55M
Total Debt1.54M1.88M637.00K2.06M3.09M0.00
Total Liabilities47.18M56.35M51.83M16.08M17.50M5.72M
Stockholders Equity196.41M214.17M176.19M126.52M20.87M15.87M
Cash Flow
Free Cash Flow-41.90M-89.20M-100.18M-117.56M-65.00M-33.24M
Operating Cash Flow-41.90M-89.20M-100.18M-117.56M-65.00M-33.24M
Investing Cash Flow0.000.00370.00K27.00K-6.00K-93.00K
Financing Cash Flow40.13M87.41M53.98M200.71M74.32M44.72M

SynAct Pharma AB Technical Analysis

Technical Analysis Sentiment
Positive
Last Price23.80
Price Trends
50DMA
21.51
Positive
100DMA
20.96
Positive
200DMA
19.85
Positive
Market Momentum
MACD
0.24
Negative
RSI
54.60
Neutral
STOCH
42.31
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SE:SYNACT, the sentiment is Positive. The current price of 23.8 is above the 20-day moving average (MA) of 21.43, above the 50-day MA of 21.51, and above the 200-day MA of 19.85, indicating a bullish trend. The MACD of 0.24 indicates Negative momentum. The RSI at 54.60 is Neutral, neither overbought nor oversold. The STOCH value of 42.31 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for SE:SYNACT.

SynAct Pharma AB Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
76
Outperform
kr2.93B4.62167.77%2687.51%
67
Neutral
kr1.24B9.8281.19%
56
Neutral
kr1.18B-10.16-58.41%48.14%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
kr1.18B-3.97131.20%32.28%
47
Neutral
kr396.46M-3.64-79.60%31.62%
42
Neutral
kr32.17M-0.21-199.25%0.30%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SE:SYNACT
SynAct Pharma AB
22.20
11.28
103.30%
SE:ONCO
Oncopeptides AB
4.57
3.15
222.51%
SE:SANION
Saniona AB
21.25
14.85
232.03%
SE:ACE
Ascelia Pharma AB
3.13
0.21
7.20%
SE:GUARD
Guard Therapeutics International AB
1.60
-17.58
-91.68%
SE:CANTA
Cantargia AB
4.98
3.27
192.65%

SynAct Pharma AB Corporate Events

SynAct Pharma Leadership Enters Lock-Up Ahead of Key Clinical Milestones
Dec 23, 2025

SynAct Pharma’s board and management have voluntarily signed lock-up agreements preventing them from selling or otherwise disposing of their shares and related securities between 1 January and 30 June 2026, allowing only customary exceptions. The move comes as the company approaches key clinical milestones, including near-completion of patient recruitment and upcoming topline data from its Phase 2b ADVANCE trial in rheumatoid arthritis and a Phase 2a study in dengue virus, and is intended to underscore leadership’s confidence in SynAct’s strategy, support transparency around market-sensitive results, and signal commitment to long-term value creation for shareholders and potential partners.

SynAct Pharma Leadership Buys Shares as Key Rheumatoid Arthritis Milestone Nears
Dec 22, 2025

SynAct Pharma AB announced that its top leadership, including the CEO, CSO, CBO, and Chairman of the Board, have collectively acquired 12,028 shares in the company on Nasdaq Stockholm, signaling internal confidence in the firm’s prospects. Management highlighted that recruitment in the company’s lead program in rheumatoid arthritis is nearing completion and that it is preparing to initiate a clinical trial in viral infection, underscoring an active late-stage pipeline and setting expectations for a data-rich 2026 that could be significant for investors and the company’s positioning within inflammatory disease therapeutics.

SynAct Pharma AB Appoints Nomination Committee for 2026 AGM
Dec 11, 2025

SynAct Pharma AB has announced the appointment of its Nomination Committee in preparation for the Annual General Meeting (AGM) 2026. The committee, comprising representatives from the three largest shareholders and the chairman of the Board, is tasked with proposing candidates for board positions and determining remuneration, reflecting the company’s commitment to transparent governance and stakeholder engagement.

SynAct Pharma to Attend J.P. Morgan Healthcare Conference for Strategic Engagements
Dec 10, 2025

SynAct Pharma announced its participation in the upcoming J.P. Morgan Healthcare Conference in San Francisco, where CEO Jeppe Øvlesen will engage with potential partners and investors. The conference presents a significant opportunity for SynAct Pharma to discuss advancements in their resomelagon treatment for rheumatoid arthritis and host-directed therapy for viral infections, potentially impacting their market positioning and stakeholder interests.

SynAct Pharma AB Implements New Share Option Program and Share Management Strategy
Nov 27, 2025

SynAct Pharma AB held an Extraordinary General Meeting where key resolutions were passed, including the implementation of an employee share option program and authorization for the Board to manage the acquisition and transfer of own shares. These measures aim to secure long-term commitment from employees and enhance the company’s capital structure, potentially increasing shareholder value.

SynAct Pharma to Present at Redeye Autoimmune and Inflammatory Diseases Event
Nov 19, 2025

SynAct Pharma AB announced its participation in the Redeye Autoimmune and Inflammatory Diseases event in Stockholm, where the company’s Chief Business Officer, Mads Bjerregaard, will present updates on their lead compound, resomelagon. This potential first-in-class, non-suppressive immune system modulator is being developed for treating rheumatoid arthritis and acute inflammation due to viral infections, highlighting SynAct’s innovative approach in the field of immunology.

SynAct Pharma Advances Resomelagon Phase 2b Study for Rheumatoid Arthritis
Nov 3, 2025

SynAct Pharma AB has made significant progress in its Phase 2b ADVANCE study for Resomelagon, a treatment for Rheumatoid Arthritis, by randomizing 190 out of 240 patients. The study aims to evaluate the efficacy of Resomelagon in combination with methotrexate therapy, potentially offering a safer and effective alternative to current treatments, which could impact the future management of Rheumatoid Arthritis, a condition projected to affect up to 32 million people by 2050.

SynAct Pharma to Engage in Strategic Discussions at BioEurope 2025
Oct 31, 2025

SynAct Pharma AB announced its participation in the BioEurope 2025 conference in Vienna, a major event for the life sciences sector with over 5,700 delegates. The company aims to discuss potential collaborations for its lead program, Resomelagon, a non-suppressive immune modulation therapy for rheumatoid arthritis and inflammation due to viral infections, highlighting its potential to support millions of patients.

SynAct Pharma’s Q3 2025 Interim Report Highlights
Oct 30, 2025

SynAct Pharma AB released its interim report for the third quarter of 2025, highlighting significant events and financial developments. The report underscores the company’s ongoing research and development efforts in inflammatory diseases, which are crucial for its market positioning and stakeholder interests.

SynAct Pharma AB Announces Extraordinary General Meeting to Discuss Key Resolutions
Oct 29, 2025

SynAct Pharma AB has announced an Extraordinary General Meeting scheduled for November 27, 2025, in Stockholm, Sweden. The meeting will address several key resolutions, including the introduction of an employee share option program (ESOP 2025), a directed issue of warrants, and authorization for the acquisition and transfer of own shares. These initiatives are likely aimed at enhancing employee engagement and optimizing the company’s capital structure, potentially impacting shareholder value and market positioning.

Edison Investment Research Initiates Coverage of SynAct Pharma
Oct 28, 2025

SynAct Pharma AB has announced that Edison Investment Research Ltd., a UK-based firm, has initiated coverage of the company. This collaboration is expected to enhance SynAct Pharma’s visibility in the pharma and biotech industry, potentially impacting its market positioning and providing stakeholders with valuable insights into its operations.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 30, 2025