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Orexo AB (SE:ORX)
:ORX
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Orexo AB (ORX) AI Stock Analysis

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SE:ORX

Orexo AB

(OTC:ORX)

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Neutral 49 (OpenAI - 4o)
Rating:49Neutral
Price Target:
kr23.00
▼(-43.90% Downside)
Orexo AB's overall stock score is primarily impacted by its poor financial performance, characterized by declining revenues and high leverage. While technical analysis shows some positive momentum, the negative P/E ratio and lack of dividend yield weigh heavily on its valuation.

Orexo AB (ORX) vs. iShares MSCI Sweden ETF (EWD)

Orexo AB Business Overview & Revenue Model

Company DescriptionOrexo AB (ORX) is a pharmaceutical company based in Sweden, specializing in the development and commercialization of innovative treatments for opioid dependence and other mental health disorders. The company operates primarily in the pharmaceutical sector, focusing on providing effective solutions for patients with unmet medical needs. Orexo's core products include Zubsolv, a medication for the treatment of opioid dependence, and other proprietary products aimed at improving patient adherence and outcomes in mental health.
How the Company Makes MoneyOrexo AB generates revenue primarily through the sale of its pharmaceutical products, particularly Zubsolv, which is marketed in the United States. The company also engages in partnerships and collaborations with other pharmaceutical firms, which can include licensing agreements and co-development initiatives that provide additional revenue streams. Furthermore, Orexo may receive milestone payments and royalties from these partnerships based on sales performance and product development achievements. The company's focus on innovative formulations and its ability to address specific patient needs contribute to its competitive advantage and financial performance.

Orexo AB Earnings Call Summary

Earnings Call Date:Jul 16, 2025
(Q3-2024)
|
% Change Since: |
Next Earnings Date:Oct 23, 2025
Earnings Call Sentiment Neutral
The earnings call presented a mixed view with notable achievements in ZUBSOLV demand stabilization in the Commercial segment and promising developments in the AmorphOX platform. However, these were offset by challenges such as the decline in ZUBSOLV revenues, delays in OX124 approval, and increased legal costs, which impacted financial performance and raised liquidity concerns.
Q3-2024 Updates
Positive Updates
ZUBSOLV Growth in Key Segment
ZUBSOLV showed stabilization in demand with growth in the Commercial segment year-over-year and quarter-over-quarter. The Commercial segment grew by 22% from the previous year, which is significant for profitability since it's more profitable than Medicaid and Medicare segments.
Successful Human Factor Study for OX124
Orexo completed a new Human Factor study for OX124, which was successful in addressing issues raised by the FDA regarding instructions for use.
AmorphOX Platform Opportunities
The AmorphOX platform has continued to show potential with ongoing feasibility projects in various chemical structures, including vaccines and biologics, indicating a stable formulation across small molecules and peptides.
Positive EBITDA Outlook
Orexo maintained a high gross margin of 86% and expects to achieve a positive EBITDA for the full year, despite current challenges.
Negative Updates
ZUBSOLV Revenue Decline
ZUBSOLV net revenues decreased by 6.7% year-over-year due to a weaker USD FX rate, declines in public demand, and an inventory destocking effect.
OX124 Approval Delay
OX124's FDA approval is delayed as additional tests and manufacturing adjustments are needed, impacting the launch timeline.
Legal and Investigation Costs
Higher legal costs were incurred due to the DOJ investigation and the ongoing ZUBSOLV patent dispute, impacting financial performance.
Cash Flow and Liquidity Concerns
Cash and cash equivalents decreased by SEK 25 million from the end of Q2, with cash flow from operating activities at minus SEK 13.4 million, raising concerns about liquidity.
Company Guidance
During Orexo's Q3 2024 earnings call, CEO Nikolaj Sørensen and CFO Frederik Jarrsten provided detailed guidance on various financial and operational metrics. The company's total revenue for the quarter was approximately SEK 136 million, with ZUBSOLV contributing SEK 131 million, marking a 6.7% year-over-year decline due to a weaker USD FX rate and reduced demand from the public sector. However, the Commercial segment exhibited robust growth, increasing by 22% from the previous year, despite a slight decline in Medicaid. Orexo's gross margin remained high at 86%, and operating expenses were reduced by 15% compared to the previous year. The company anticipates positive EBITDA for the full year, although inventory adjustments and potential DOJ investigation settlements could impact future financial results. Sørensen highlighted the importance of the upcoming FDA meeting regarding OX124 and expressed optimism about the stabilization in ZUBSOLV demand, particularly in the Commercial segment, which is more profitable. The company is also exploring strategic options to enhance its equity position and leverage its AmorphOX platform for future growth.

Orexo AB Financial Statement Overview

Summary
Orexo AB faces significant financial challenges with declining revenues, persistent losses, high leverage, and negative equity. Despite slight improvements in cash flow, the company's financial health remains strained, indicating a need for strategic interventions.
Income Statement
30
Negative
Orexo AB's income statement shows a concerning trend with declining revenues and consistent net losses over recent years. The gross profit margin remains strong at 86.7% TTM, but the company struggles with significant negative EBIT and net profit margins, indicating operational inefficiencies. Despite a slight revenue growth in TTM, the overall trajectory suggests financial instability.
Balance Sheet
25
Negative
The balance sheet of Orexo AB reveals a negative stockholders' equity, indicative of financial distress. The debt-to-equity ratio cannot be calculated due to negative equity, underscoring high leverage and potential solvency issues. An equity ratio of -30.5% TTM highlights a precarious capital structure with total liabilities outweighing total assets.
Cash Flow
40
Negative
Orexo AB has shown slight improvement in free cash flow recently, moving from negative to positive territory TTM. However, the operating cash flow remains weak relative to net income, reflecting difficulties in converting sales to cash. Despite the improvement in free cash flow, the overall cash flow position suggests liquidity challenges.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue561.20M590.00M638.80M624.30M565.00M663.60M
Gross Profit489.70M517.90M549.90M521.70M486.10M598.00M
EBITDA28.00M58.60M-32.30M-73.90M-141.30M16.80M
Net Income-213.80M-203.00M-128.30M-177.60M-223.50M-84.40M
Balance Sheet
Total Assets533.40M594.80M786.60M1.11B1.27B1.23B
Cash, Cash Equivalents and Short-Term Investments121.30M123.30M171.00M351.80M504.10M505.30M
Total Debt495.60M476.00M473.80M539.60M550.50M291.00M
Total Liabilities730.40M721.10M727.70M915.10M924.10M674.40M
Stockholders Equity-197.00M-126.30M58.90M193.90M349.60M558.50M
Cash Flow
Free Cash Flow24.20M-37.20M-113.90M-180.50M-281.80M-172.90M
Operating Cash Flow25.00M-32.60M-95.00M-156.60M-229.00M16.80M
Investing Cash Flow-20.70M-5.30M200.80M-234.70M-52.90M-189.10M
Financing Cash Flow-13.30M-15.50M-70.10M-21.40M250.60M-111.30M

Orexo AB Technical Analysis

Technical Analysis Sentiment
Positive
Last Price41.00
Price Trends
50DMA
25.37
Positive
100DMA
22.17
Positive
200DMA
19.25
Positive
Market Momentum
MACD
4.18
Negative
RSI
77.88
Negative
STOCH
96.62
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SE:ORX, the sentiment is Positive. The current price of 41 is above the 20-day moving average (MA) of 31.75, above the 50-day MA of 25.37, and above the 200-day MA of 19.25, indicating a bullish trend. The MACD of 4.18 indicates Negative momentum. The RSI at 77.88 is Negative, neither overbought nor oversold. The STOCH value of 96.62 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for SE:ORX.

Orexo AB Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$1.35B-8.81%-120.57%
47
Neutral
€301.08M-161.07%22.73%
44
Neutral
€326.37M-34.87%-38.56%69.37%
41
Neutral
€129.88M-3899.10%1523.75%20.82%
41
Neutral
kr526.74M11.87%26.50%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SE:ORX
Orexo AB
41.00
27.28
198.83%
SE:ALZCUR
AlzeCure Pharma AB
2.50
0.78
45.77%
SE:KLAR
Klaria Pharma Holding AB
0.51
-0.05
-9.77%
SE:NANEXA
Nanexa AB
2.09
0.65
44.79%
SE:ENZY
Enzymatica AB
2.12
0.22
11.58%
SE:ERMA
Enorama Pharma AB
2.41
-1.79
-42.62%

Orexo AB Corporate Events

Orexo AB Reports Q2 2025 Financial Results Amid Challenges
Jul 16, 2025

Orexo AB reported a challenging second quarter of 2025, with total net revenues of SEK 118.2 million, impacted by currency headwinds and a non-recurring rebate payment. The company experienced a negative EBITDA of SEK -10.1 million and net earnings of SEK -39.8 million. Despite these financial challenges, Orexo announced positive in-vivo data for its intranasal vaccine developed with Abera Bioscience and presented clinical data for its OX640 intranasal rescue medication. The election of Friedrich von Bohlen as the new Chairman of the Board marks a significant leadership change.

Orexo AB Announces Changes in Share and Vote Structure
Jun 30, 2025

Orexo AB announced a change in the number of shares and votes due to the issuance and repurchase of class C shares. The total number of shares increased to 37,156,639, with a corresponding increase in votes to 34,955,239. This adjustment could impact the company’s shareholder structure and voting dynamics, potentially influencing future corporate decisions.

Orexo AB Issues and Repurchases Class C Shares for Incentive Programs
Jun 18, 2025

Orexo AB has announced the issuance and immediate repurchase of 2,446,000 class C shares to support its long-term incentive programs from 2023 to 2025. These shares, initially subscribed by Danske Bank, will be converted into ordinary shares for distribution to program participants, ensuring the company’s commitment to its incentive schemes.

Orexo to Showcase OX640 Clinical Data at EAACI Congress
Jun 2, 2025

Orexo AB announced its participation in the 2025 EAACI Congress, where it will present clinical data for its nasal rescue medication, OX640. This product, based on the AmorphOX® technology, shows promise for rapid and effective treatment of severe allergic reactions, including anaphylaxis. The clinical study demonstrated that OX640 allows for faster absorption of epinephrine under allergic conditions, suggesting a rapid onset of action. The presentation at EAACI, a leading global association for allergy and immunology diseases, underscores Orexo’s commitment to advancing treatment options in this field.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 06, 2025