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Rigel (RIGL)
NASDAQ:RIGL

Rigel (RIGL) AI Stock Analysis

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RI

Rigel

(NASDAQ:RIGL)

74Outperform
Rigel Pharmaceuticals exhibits strong financial performance with significant revenue and profit growth, alongside effective cash flow management. While the company's high leverage poses a risk, recent improvements in equity and operational efficiency are promising. The technical analysis shows moderate potential, and valuation appears attractive, though lacking a dividend yield. The earnings call confirms robust growth prospects, despite minor concerns. Overall, Rigel is positioned well in the biotechnology sector, with potential for further gains if it maintains its momentum.
Positive Factors
Clinical Trials
Rigel Pharmaceuticals has announced the enrollment of the first patient in its Phase 1 trial evaluating fostamatinib in sickle cell disease, highlighting a significant step forward in exploring the drug's potential to address unmet needs in this condition.
International Expansion
Approval from the Korean Ministry of Food and Drug Safety for Tavalisse boosts Rigel's presence in the international market.
Revenue Growth
Rigel Pharmaceuticals reported higher-than-expected revenue growth, primarily driven by stronger-than-projected sales of Gavreto and Tavalisse.
Negative Factors
Product Portfolio
The company aims to continue expanding its commercial portfolio and drive product sales by broadening access to its therapies beyond the U.S.
Strategic Decisions
Rigel decided not to exercise its opt-in right for ocadusertib under its agreement with Eli Lilly, based on internal strategic prioritization.

Rigel (RIGL) vs. S&P 500 (SPY)

Rigel Business Overview & Revenue Model

Company DescriptionRigel Pharmaceuticals, Inc., a biotechnology company, discovers and develops small molecule drugs to treat hematologic disorders, cancer, and rare immune diseases. The company offers Tavalisse, an oral spleen tyrosine kinase inhibitor for the treatment of adult patients with chronic immune thrombocytopenia. It also develops Fostamatinib that is in phase III clinical trial for the treatment of warm autoimmune hemolytic anemia; phase III clinical trial for the treatment of hospitalized COVID-19 patients; and phase III clinical trial for the treatment of COVID-19. In addition, the company is developing R289, an oral interleukin receptor associated kinase 1/4 inhibitor, which is in phase I clinical trial for autoimmune, inflammatory, and hematology-oncology diseases; and R552, a receptor-interacting serine/threonine-protein kinase 1 inhibitor that has completed phase I clinical trial for autoimmune and inflammatory diseases. It has research and license agreements with AstraZeneca AB for the development and commercialization of R256, an inhaled JAK inhibitor; BerGenBio AS for the development and commercialization of AXL inhibitors in oncology; and Daiichi Sankyo to develop murine double minute 2 inhibitors for solid and hematological malignancies, as well as license and supply agreement with Kissei Pharmaceutical Co., Ltd. to develop and commercialize Fostamatinib. The company also has a license agreement and strategic collaboration with Eli Lilly and Company to co-develop and commercialize R552 for various indications, including autoimmune and inflammatory diseases, as well as other non-central nervous system (non-CNS) disease development candidates. Rigel Pharmaceuticals, Inc. was incorporated in 1996 and is headquartered in South San Francisco, California.
How the Company Makes MoneyRigel Pharmaceuticals generates revenue through the commercialization of its pharmaceutical products, primarily focusing on its flagship product, TAVALISSE (fostamatinib disodium hexahydrate), an oral spleen tyrosine kinase (SYK) inhibitor for adult chronic immune thrombocytopenia (ITP). The company earns money from product sales, collaborations, and licensing agreements with other pharmaceutical and biotechnology companies. Additionally, Rigel receives milestone payments and royalties from partnerships that leverage its proprietary compounds and technologies. These strategic collaborations are crucial for the company's financial growth, enabling it to share research and development costs and expand its market presence.

Rigel Financial Statement Overview

Summary
Rigel has demonstrated strong revenue growth and improved profitability, with a significant improvement in net profit margin. However, historical volatility and high leverage pose risks.
Income Statement
75
Positive
Rigel has demonstrated a strong revenue growth of 53.4% from 2023 to 2024, with a significant improvement in net profit margin from negative in 2023 to 9.75% in 2024. The gross profit margin remains robust at 89.59%. The positive EBIT and EBITDA margins in 2024 reflect improved operational efficiency. However, the company has historically experienced volatility in profitability, which poses potential risks.
Balance Sheet
60
Neutral
The debt-to-equity ratio is high due to low stockholders' equity, indicating significant leverage at 18.24. Despite this, the company has managed to turn equity positive in 2024, a positive sign after a negative equity period. The equity ratio remains low at 2%, highlighting a significant reliance on debt financing, which could be risky if revenue growth slows.
Cash Flow
80
Positive
Rigel's free cash flow has improved significantly, with a free cash flow growth rate of 251.5% from 2023 to 2024. The operating cash flow to net income ratio is 1.8, indicating strong cash generation relative to earnings. The free cash flow to net income ratio of 1.8 also reflects efficient cash flow management. However, prior years showed negative cash flows, suggesting a need for sustained performance.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
179.28M116.88M120.24M149.24M108.62M
Gross Profit
160.63M109.77M118.49M148.15M107.73M
EBIT
24.19M-20.49M-54.23M-8.97M-28.97M
EBITDA
28.51M-16.98M-53.87M-11.29M-27.68M
Net Income Common Stockholders
17.48M-25.09M-61.60M-17.91M-30.39M
Balance SheetCash, Cash Equivalents and Short-Term Investments
77.32M56.93M58.21M124.97M57.33M
Total Assets
163.98M117.22M134.28M167.33M110.38M
Total Debt
59.97M60.58M41.55M30.57M39.09M
Net Debt
3.22M27.79M17.09M11.68M8.71M
Total Liabilities
160.69M145.87M147.90M136.95M76.35M
Stockholders Equity
3.29M-28.64M-13.62M30.37M34.03M
Cash FlowFree Cash Flow
31.43M-20.74M-74.21M5.25M-53.45M
Operating Cash Flow
31.47M-5.74M-73.76M5.88M-52.19M
Investing Cash Flow
4.13M-4.30M72.78M-80.04M47.47M
Financing Cash Flow
-11.64M18.37M6.55M62.67M12.57M

Rigel Technical Analysis

Technical Analysis Sentiment
Negative
Last Price18.29
Price Trends
50DMA
18.74
Negative
100DMA
19.27
Negative
200DMA
17.83
Positive
Market Momentum
MACD
0.07
Negative
RSI
47.54
Neutral
STOCH
19.63
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RIGL, the sentiment is Negative. The current price of 18.29 is below the 20-day moving average (MA) of 18.43, below the 50-day MA of 18.74, and above the 200-day MA of 17.83, indicating a neutral trend. The MACD of 0.07 indicates Negative momentum. The RSI at 47.54 is Neutral, neither overbought nor oversold. The STOCH value of 19.63 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for RIGL.

Rigel Risk Analysis

Rigel disclosed 60 risk factors in its most recent earnings report. Rigel reported the most risks in the “Legal & Regulatory” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Rigel Peers Comparison

Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
74
Outperform
$332.61M8.83531.78%68.74%
62
Neutral
$334.75M10.767.22%5.74%24.45%
55
Neutral
$399.43M-47.44%80.70%46.66%
52
Neutral
$5.22B3.55-44.39%2.82%15.40%-0.09%
50
Neutral
$312.76M40.36%12.43%91.67%
IVIVA
50
Neutral
$496.77M344.74%-47.32%-26.67%
43
Neutral
$387.86M-58.31%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RIGL
Rigel
18.29
8.60
88.75%
HRTX
Heron Therapeutics
1.84
-1.16
-38.67%
RGNX
RegenXBio
8.18
-8.05
-49.60%
MREO
Mereo Biopharma Group Plc
2.32
-0.85
-26.81%
IVA
Inventiva
3.58
-0.16
-4.28%
TRDA
Entrada Therapeutics Inc
8.70
-5.79
-39.96%

Rigel Earnings Call Summary

Earnings Call Date:May 06, 2025
(Q1-2025)
|
% Change Since: 0.16%|
Next Earnings Date:Aug 05, 2025
Earnings Call Sentiment Positive
The earnings call highlighted significant financial growth and strategic advancements in product development and international market expansion. Despite minor concerns about potential tariffs and decisions regarding development expenses with Lilly, Rigel's overall performance and outlook remain strong.
Q1-2025 Updates
Positive Updates
Significant Revenue Growth
Rigel Pharmaceuticals reported a 68% year-over-year net product sales growth, with total revenue of $53.3 million for the quarter.
Positive Financial Performance
Generated $11.4 million in net income for the quarter, demonstrating a profitable start to the fiscal year.
Expansion of Product Portfolio
The commercial portfolio now includes three products: TAVALISSE, GAVRETO, and REZLIDHIA, with each showing significant sales growth.
Successful International Expansion
TAVALISSE is now commercially available in several international markets, including Japan, Europe, Canada, Israel, and Mexico.
Advancement in Development Pipeline
Progress in the clinical development of R289 and olutasidenib, with plans for a Phase II study in recurrent glioma.
Strategic Collaborations
Partnerships with MD Anderson and CONNECT to advance the potential of olutasidenib in multiple indications.
Negative Updates
Potential Tariffs Impact
Possible impact of global trade tensions and potential tariffs on manufacturing costs, though expected to be modest.
RIP Kinase 1 Inhibitor Program Update
Decided not to exercise the right to share future development expenses for ocadusertib, which could affect future royalty rates.
Company Guidance
During the first quarter of 2025, Rigel Pharmaceuticals reported robust year-over-year growth, with net product sales increasing by 68% to $43.6 million. The growth was driven by the addition of GAVRETO to their portfolio, as well as continued momentum in sales of TAVALISSE and REZLIDHIA. TAVALISSE alone contributed $28.5 million in net product sales, reflecting a 35% increase compared to the same period in 2024. The total revenue for the quarter reached $53.3 million, including $9.8 million from collaborations. Notably, Rigel achieved a net income of $11.4 million during a time when the business environment is challenging for the biotech sector. The company maintained its guidance for 2025, expecting total revenue between $200 million and $210 million and a positive net income for the full year. Additionally, Rigel highlighted the progress in their development pipeline, including R289, a dual IRAK1 and 4 inhibitor, and plans to expand olutasidenib into a Phase II study for recurrent glioma.

Rigel Corporate Events

Executive/Board Changes
Rigel Pharmaceuticals Appoints Dr. Frohlich to Board
Neutral
Mar 10, 2025

On March 6, 2025, Rigel Pharmaceuticals appointed Dr. Mark J. Frohlich to its board of directors, where he will serve on several committees, including the Corporate Governance, Health Care Compliance Oversight and Nominating Committee, and the Scientific and Clinical Trial Advisory Committee. Dr. Frohlich will receive standard non-employee director compensation, including cash retainers and stock options, and has been deemed independent under relevant governance guidelines, with no conflicts of interest or family ties within the company.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.