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Rigel (RIGL)
NASDAQ:RIGL

Rigel (RIGL) AI Stock Analysis

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RIGL

Rigel

(NASDAQ:RIGL)

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Outperform 78 (OpenAI - 4o)
Rating:78Outperform
Price Target:
$47.00
▲(13.01% Upside)
Rigel Pharmaceuticals scores well due to its strong financial performance and positive earnings call, which highlight robust revenue growth and strategic advancements. The technical analysis and valuation suggest moderate momentum and potential undervaluation, while recent corporate events further bolster the company's growth outlook.
Positive Factors
Revenue Growth
Strong revenue growth indicates successful product adoption and market expansion, supporting long-term financial stability and growth potential.
Pipeline Advancements
Advancements in the R289 study enhance Rigel's pipeline, potentially leading to new product approvals and sustained growth in hematology and oncology.
Strategic Collaborations
Collaborations expand Rigel's research capabilities and market reach, leveraging proprietary technologies for long-term competitive advantage.
Negative Factors
Low Equity Ratio
A low equity ratio may limit Rigel's ability to withstand financial downturns, posing a risk to long-term financial stability.
Program Termination
Termination of the CNS program may impact Rigel's diversification efforts, potentially reducing future revenue streams and growth opportunities.
Debt Levels
While leverage is manageable, increasing debt levels could strain cash flow and limit Rigel's financial flexibility, affecting long-term operations.

Rigel (RIGL) vs. SPDR S&P 500 ETF (SPY)

Rigel Business Overview & Revenue Model

Company DescriptionRigel Pharmaceuticals, Inc. (RIGL) is a biotechnology company focused on the discovery and development of innovative treatments for hematologic disorders and autoimmune diseases. The company specializes in developing small molecule drugs that target specific pathways in disease processes, with an emphasis on conditions such as immune thrombocytopenia (ITP) and other related hematological conditions. Rigel's core products include its lead drug candidates and potential therapies in various stages of clinical trials, aimed at improving patient outcomes in these underserved areas.
How the Company Makes MoneyRigel generates revenue primarily through the commercialization of its pharmaceutical products, including royalties and product sales from its approved therapies. Key revenue streams also include milestone payments from partnerships with larger pharmaceutical companies, which may involve collaborations for the development and marketing of its drug candidates. The company may receive funding from government grants or research institutions focusing on innovative medical treatments. Additionally, Rigel's financial performance is bolstered by strategic partnerships and collaborations that enhance its research capabilities and market reach, allowing it to leverage its proprietary technologies and drug development expertise.

Rigel Earnings Call Summary

Earnings Call Date:Nov 04, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 03, 2026
Earnings Call Sentiment Positive
The earnings call highlighted Rigel Pharmaceuticals' strong financial performance, significant increases in revenue and net product sales, and advancements in their drug development pipeline. Despite the termination of a specific CNS program by Eli Lilly, the overall tone was positive, focusing on growth and expansion opportunities.
Q3-2025 Updates
Positive Updates
Record Revenue and Net Product Sales
Total revenue of $69.5 million for Q3 2025, with record net product sales of $64.1 million, a 65% year-over-year increase. Raised 2025 revenue guidance to $285 million to $290 million, exceeding previous expectations.
Strong Performance of Commercial Products
TAVALISSE generated $44.7 million in net product sales, a 70% increase from Q3 2024. GAVRETO achieved $11.1 million, a 56% increase, and REZLIDHIA reported $8.3 million, a 50% increase.
Pipeline Advancements
Completion of enrollment in the dose escalation phase of the R289 study. First patient enrolled in the dose expansion phase. Strategic collaborations and expansions for olutasidenib in IDH1 mutated AML and glioma.
Financial Discipline and Profitability
Reported net income of $27.9 million for Q3 2025, up from $12.4 million in Q3 2024. Increased cash balance to $137.1 million.
Negative Updates
Termination of CNS Disease Program
Eli Lilly decided to terminate the CNS disease program, which will become effective after 60 days.
Company Guidance
During Rigel Pharmaceuticals' third-quarter 2025 financial conference call, the company provided updated guidance for the year, reflecting a strong commercial performance and strategic advancements in their development pipeline. Total revenue for the third quarter reached $69.5 million, driven by record net product sales of $64.1 million, marking a 65% year-over-year increase. Rigel's updated 2025 revenue guidance now projects total revenue between $285 million and $290 million, up from a previous range of $270 million to $280 million, with net product sales expected to be between $225 million and $230 million. This represents an anticipated growth rate of 55% to 59% compared to 2024. The company also reported a net income of $27.9 million for the quarter and increased their cash balance to $137.1 million. Additionally, Rigel highlighted its progress in the ongoing Phase Ib study of R289 and strategic collaborations for olutasidenib, contributing to a promising outlook for sustained growth and development in hematology and oncology.

Rigel Financial Statement Overview

Summary
Rigel demonstrates strong profitability with high margins and consistent revenue growth. The balance sheet is moderate with manageable leverage, but could benefit from a stronger equity position. Cash flow is solid, supporting earnings efficiently.
Income Statement
85
Very Positive
Rigel's income statement shows strong profitability with a high gross profit margin of 93.10% and a net profit margin of 40.17% in the TTM period. The company has demonstrated consistent revenue growth, with a 5.28% increase in the latest TTM period. EBIT and EBITDA margins are also robust at 32.76% and 43.47%, respectively, indicating efficient cost management and operational performance.
Balance Sheet
70
Positive
The balance sheet reflects a moderate financial position with a debt-to-equity ratio of 0.52, suggesting manageable leverage. The return on equity is 4.39%, indicating decent profitability relative to shareholder equity. However, the equity ratio is relatively low, highlighting potential risks if asset values decline.
Cash Flow
75
Positive
Cash flow analysis reveals positive trends with a 3.01% growth in free cash flow. The operating cash flow to net income ratio is 0.72, indicating that a significant portion of net income is supported by cash flow. The free cash flow to net income ratio is nearly 1, showing efficient conversion of earnings into cash.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue282.08M179.28M116.88M120.24M149.24M108.62M
Gross Profit262.62M160.63M109.77M118.49M148.15M107.73M
EBITDA124.33M28.51M-16.98M-53.87M-11.29M-27.68M
Net Income113.30M17.48M-25.09M-58.57M-17.91M-29.74M
Balance Sheet
Total Assets242.53M163.98M117.22M134.28M167.33M110.38M
Cash, Cash Equivalents and Short-Term Investments137.14M77.32M56.93M58.21M124.97M57.33M
Total Debt60.88M59.97M60.58M41.55M30.57M39.09M
Total Liabilities124.92M160.69M145.87M147.90M136.95M76.35M
Stockholders Equity117.61M3.29M-28.64M-13.62M30.37M34.03M
Cash Flow
Free Cash Flow68.14M31.07M-20.74M-74.21M5.25M-53.45M
Operating Cash Flow68.18M31.47M-5.74M-73.76M5.88M-52.19M
Investing Cash Flow-77.92M4.13M-4.30M72.78M-80.04M47.47M
Financing Cash Flow6.64M-11.64M18.37M6.55M62.67M12.57M

Rigel Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price41.59
Price Trends
50DMA
38.13
Positive
100DMA
36.13
Positive
200DMA
27.66
Positive
Market Momentum
MACD
0.45
Positive
RSI
48.40
Neutral
STOCH
25.19
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RIGL, the sentiment is Neutral. The current price of 41.59 is below the 20-day moving average (MA) of 45.09, above the 50-day MA of 38.13, and above the 200-day MA of 27.66, indicating a neutral trend. The MACD of 0.45 indicates Positive momentum. The RSI at 48.40 is Neutral, neither overbought nor oversold. The STOCH value of 25.19 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for RIGL.

Rigel Risk Analysis

Rigel disclosed 59 risk factors in its most recent earnings report. Rigel reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Rigel Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
78
Outperform
$754.91M6.74220.06%79.13%2798.12%
54
Neutral
$738.59M-4.18-76.88%91.30%30.69%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$425.18M-6.17-45.92%1255.21%74.58%
47
Neutral
$476.14M-34.63%-23.43%-9.84%
44
Neutral
$584.48M-1.82-2888.70%33.79%-26.37%
39
Underperform
$477.76M-3.01-80.09%60.14%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RIGL
Rigel
41.59
24.44
142.51%
LXRX
Lexicon Pharmaceuticals
1.17
0.34
40.96%
VSTM
Verastem
7.76
3.80
95.96%
RGNX
RegenXBio
14.59
7.21
97.70%
BCYC
Bicycle Therapeutics
6.87
-7.67
-52.75%
OPT
Opthea Limited Sponsored ADR
0.04
-3.57
-98.89%

Rigel Corporate Events

Product-Related Announcements
Rigel Pharmaceuticals Reports Promising Phase 1b Study Results
Positive
Dec 10, 2025

On December 7, 2025, Rigel Pharmaceuticals announced updated data from its ongoing Phase 1b study of R289, an oral prodrug, in patients with relapsed or refractory lower-risk myelodysplastic syndrome (MDS). The study, presented at the 67th ASH Annual Meeting, showed that R289 was generally well tolerated and demonstrated preliminary efficacy, with 33% of evaluable transfusion-dependent patients achieving red blood cell transfusion independence. These results underscore the potential of R289 as a treatment option for lower-risk MDS patients, with further clinical trials anticipated in the second half of 2026.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 11, 2025