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Rigel Pharmaceuticals (RIGL)
NASDAQ:RIGL
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Rigel (RIGL) AI Stock Analysis

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RIGL

Rigel

(NASDAQ:RIGL)

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Outperform 79 (OpenAI - 5.2)
Rating:79Outperform
Price Target:
$47.00
▲(44.93% Upside)
Action:Reiterated
Date:06/23/26
The score is driven primarily by a strong financial inflection (rapid revenue growth, high recent profitability, and positive free cash flow) and very attractive valuation via an extremely low P/E. Technicals support an uptrend but appear overextended (RSI/Stoch elevated), and the earnings outlook is constructive with reiterated guidance and expected full-year profitability, tempered by rising expenses and collaboration-related uncertainty.
Positive Factors
Sustained revenue & profitability inflection
Rigel's sharp TTM revenue rise and recently outsized operating and net margins reflect durable commercial traction across its portfolio. This supports ongoing cash generation and reinvestment capacity, underpinning the company’s ability to fund pipeline work and execute inorganic deals over the next several quarters.
Negative Factors
Earnings quality and cash timing risk
Although reported earnings are strong, operating cash flow trails net income materially, implying non‑cash gains or timing effects could be inflating reported profits. If working capital or non‑cash adjustments normalize, free cash generation could be weaker than accounting profits suggest, pressuring reinvestment plans.
Read all positive and negative factors
Positive Factors
Negative Factors
Sustained revenue & profitability inflection
Rigel's sharp TTM revenue rise and recently outsized operating and net margins reflect durable commercial traction across its portfolio. This supports ongoing cash generation and reinvestment capacity, underpinning the company’s ability to fund pipeline work and execute inorganic deals over the next several quarters.
Read all positive factors

Rigel (RIGL) vs. SPDR S&P 500 ETF (SPY)

Rigel Business Overview & Revenue Model

Company Description
Rigel Pharmaceuticals, Inc., a biotechnology company, develops and provides therapies that enhance the lives of patients with hematologic disorders and cancer in the United States. The company offers TAVALISSE, an oral spleen tyrosine kinase inhib...
How the Company Makes Money
Rigel makes money primarily from (1) product sales of its commercial medicines and (2) collaboration and licensing-related revenue. Product revenue is generated from net sales of TAVALISSE and REZLIDHIA in the U.S., which flow through typical biop...

Rigel Earnings Call Summary

Earnings Call Date:May 05, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Aug 04, 2026
Earnings Call Sentiment Positive
The call conveys a generally positive commercial and strategic outlook: strong top-line product growth (26% YoY overall; 31% YoY for TAVALISSE and REZLIDHIA), clear 2026 guidance and a pathway to full-year profitability, alongside promising early clinical data for R289 and expanded international partner revenues. Offsetting risks include rising operating expenses, a modest decline in quarterly net income and cash, seasonal Q1 reimbursement headwinds, a slower-growing GAVRETO franchise, and the termination of the Lilly collaboration for the RIPK1 asset (creating program-level uncertainty). On balance, the highlights—robust product sales growth, maintained guidance, pipeline progress and improved financing flexibility—outweigh the lowlights.
Positive Updates
Strong Quarterly Net Product Sales Growth
Net product sales of $54.9M in Q1 2026, up 26% year-over-year (+$11.3M vs Q1 2025), driven by across‑portfolio strength and improving demand in March.
Negative Updates
Decline in Quarterly Net Income
Net income was $8.7M in Q1 2026, down from $11.4M in Q1 2025 (≈23.7% decrease year-over-year), reflecting higher operating costs despite revenue growth.
Read all updates
Q1-2026 Updates
Negative
Strong Quarterly Net Product Sales Growth
Net product sales of $54.9M in Q1 2026, up 26% year-over-year (+$11.3M vs Q1 2025), driven by across‑portfolio strength and improving demand in March.
Read all positive updates
Company Guidance
Management reiterated 2026 guidance for total revenues of $275–$290 million, comprising net product sales of $255–$265 million and contract revenues of $20–$25 million, and affirmed their expectation to deliver positive net income for the full year. In Q1 they reported total revenue of $58.8M (net product sales $54.9M, +26% YoY) including TAVALISSE $37.3M (+31%), GAVRETO $9.6M (+7%) and REZLIDHIA $8.0M (+31%), plus $3.9M collaboration revenue; net product sales were recorded net of $20.5M of discounts/allowances. Q1 cost of product sales was ~$4.6M, total costs and expenses were $46.9M (vs. $40.6M prior year), income before taxes $11.7M and net income $8.7M (vs. $11.4M). Balance sheet and financing items noted: cash, cash equivalents and short‑term investments of $146.7M (down from $155.0M at 12/31/25), repayment of a $40M term loan and establishment of a $40M revolving credit facility (option to increase to $60M) with $8M drawn; guidance excludes any assumed revenues from the Lilly collaboration.

Rigel Financial Statement Overview

Summary
Strong turnaround with sharply higher TTM revenue and very strong recent operating/net margins, alongside improved balance-sheet leverage and positive TTM operating/free cash flow. Key offset is durability risk: results have swung materially over the last 5 years (losses/negative equity earlier), and cash flow trails reported net income, raising earnings-quality/consistency questions.
Income Statement
82
Very Positive
Balance Sheet
74
Positive
Cash Flow
76
Positive
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue299.77M294.28M179.28M116.88M120.24M149.24M
Gross Profit279.95M274.66M160.63M109.77M118.49M148.15M
EBITDA131.28M131.56M28.51M-16.98M-53.87M-11.29M
Net Income364.23M367.02M17.48M-25.09M-58.57M-17.91M
Balance Sheet
Total Assets504.61M513.59M163.98M117.22M134.28M167.33M
Cash, Cash Equivalents and Short-Term Investments146.68M154.96M77.32M56.93M58.21M124.97M
Total Debt45.72M53.30M59.97M60.58M41.55M30.57M
Total Liabilities104.71M122.11M160.69M145.87M147.90M136.95M
Stockholders Equity399.90M391.48M3.29M-28.64M-13.62M30.37M
Cash Flow
Free Cash Flow79.27M75.66M31.07M-20.74M-74.21M5.25M
Operating Cash Flow79.27M75.66M31.47M-5.74M-73.76M5.88M
Investing Cash Flow-89.79M-92.36M4.13M-4.30M72.78M-80.04M
Financing Cash Flow-10.80M601.00K-11.64M18.37M6.55M62.67M

Rigel Technical Analysis

Technical Analysis Sentiment
Positive
Last Price32.43
Price Trends
50DMA
33.24
Positive
100DMA
31.41
Positive
200DMA
34.37
Positive
Market Momentum
MACD
2.65
Positive
RSI
67.27
Neutral
STOCH
52.55
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RIGL, the sentiment is Positive. The current price of 32.43 is below the 20-day moving average (MA) of 38.66, below the 50-day MA of 33.24, and below the 200-day MA of 34.37, indicating a bullish trend. The MACD of 2.65 indicates Positive momentum. The RSI at 67.27 is Neutral, neither overbought nor oversold. The STOCH value of 52.55 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for RIGL.

Rigel Risk Analysis

Rigel disclosed 59 risk factors in its most recent earnings report. Rigel reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Rigel Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
79
Outperform
$761.73M2.05147.03%47.61%854.73%
56
Neutral
$489.46M-2.29-486.41%395.85%21.44%
55
Neutral
$635.36M-2.19-232.50%-43.96%-78.31%
53
Neutral
$941.70M-30.81-18.64%123.12%86.10%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
$293.47M-1.34-35.74%146.03%-0.87%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RIGL
Rigel
41.18
21.90
113.59%
LXRX
Lexicon Pharmaceuticals
2.20
0.91
70.54%
VSTM
Verastem
5.73
0.48
9.14%
RGNX
RegenXBio
12.27
3.77
44.35%
BCYC
Bicycle Therapeutics
4.22
-3.56
-45.76%

Rigel Corporate Events

Executive/Board Changes
Rigel Appoints Alison Hannah as New Chief Medical Officer
Neutral
Jul 1, 2026
Rigel Pharmaceuticals, Inc. announced on July 1, 2026 that Alison L. Hannah, M.D., a long-time oncology development consultant and former chief medical officer at other biotech firms, has been appointed Executive Vice President and Chief Medical O...
Business Operations and StrategyM&A TransactionsRegulatory Filings and Compliance
Rigel Expands Oncology Portfolio with VEPPANU Global Rights
Positive
Jun 17, 2026
Rigel Pharmaceuticals, Inc. has secured exclusive, global rights to develop, manufacture and commercialize VEPPANU (vepdegestrant) and related products under a license agreement with Arvinas, Inc., its affiliates and Pfizer Inc., as previously dis...
Business Operations and StrategyExecutive/Board ChangesShareholder Meetings
Rigel Shareholders Approve Equity Plans and Board Slate
Positive
May 20, 2026
At its May 14, 2026 annual meeting, Rigel Pharmaceuticals’ stockholders approved amendments to the company’s 2018 Equity Incentive Plan and 2000 Employee Stock Purchase Plan, adding 500,000 and 360,000 shares, respectively, to the pool...
Business Operations and StrategyProduct-Related Announcements
Rigel Secures Global Rights to VEPPANU Breast Cancer Therapy
Positive
May 12, 2026
On May 11, 2026, Rigel Pharmaceuticals entered into a license agreement with Arvinas and Pfizer to obtain exclusive worldwide rights to develop, manufacture and commercialize VEPPANU (vepdegestrant) and related products, consolidating Rigel’...
Business Operations and Strategy
Rigel Regains Rights as Eli Lilly Ends Collaboration
Negative
Apr 21, 2026
On April 16, 2026, Rigel Pharmaceuticals received notice that Eli Lilly is terminating their 2021 license and collaboration agreement, which will become effective June 15, 2026. The deal had granted Lilly exclusive global rights to develop and com...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 23, 2026