tiprankstipranks
Trending News
More News >
Rigel (RIGL)
NASDAQ:RIGL
Advertisement

Rigel (RIGL) AI Stock Analysis

Compare
1,479 Followers

Top Page

RIGL

Rigel

(NASDAQ:RIGL)

Rating:74Outperform
Price Target:
$33.00
▼(-16.48% Downside)
Rigel Pharmaceuticals' overall stock score is driven by strong financial performance and a highly positive earnings call, highlighting significant revenue growth and increased profitability. The technical analysis indicates strong momentum, although caution is warranted due to overbought signals. The stock's undervaluation presents an attractive opportunity, but high leverage remains a concern.
Positive Factors
Clinical Trial Results
Final ARROW trial data show GAVRETO’s strong efficacy and safety.
Regulatory Approval
Approval from the Korean Ministry of Food and Drug Safety for Tavalisse boosts Rigel's presence in the international market.
Revenue Growth
Rigel Pharmaceuticals reported higher-than-expected revenue growth, primarily driven by stronger-than-projected sales of Gavreto and Tavalisse.
Negative Factors
Strategic Decisions
Rigel decided not to exercise its opt-in right for ocadusertib under its agreement with Eli Lilly, based on internal strategic prioritization.
Strategic Focus
The company is focusing on expanding its commercial portfolio and increasing product sales by exploring international partnerships.

Rigel (RIGL) vs. SPDR S&P 500 ETF (SPY)

Rigel Business Overview & Revenue Model

Company DescriptionRigel Pharmaceuticals, Inc., a biotechnology company, discovers and develops small molecule drugs to treat hematologic disorders, cancer, and rare immune diseases. The company offers Tavalisse, an oral spleen tyrosine kinase inhibitor for the treatment of adult patients with chronic immune thrombocytopenia. It also develops Fostamatinib that is in phase III clinical trial for the treatment of warm autoimmune hemolytic anemia; phase III clinical trial for the treatment of hospitalized COVID-19 patients; and phase III clinical trial for the treatment of COVID-19. In addition, the company is developing R289, an oral interleukin receptor associated kinase 1/4 inhibitor, which is in phase I clinical trial for autoimmune, inflammatory, and hematology-oncology diseases; and R552, a receptor-interacting serine/threonine-protein kinase 1 inhibitor that has completed phase I clinical trial for autoimmune and inflammatory diseases. It has research and license agreements with AstraZeneca AB for the development and commercialization of R256, an inhaled JAK inhibitor; BerGenBio AS for the development and commercialization of AXL inhibitors in oncology; and Daiichi Sankyo to develop murine double minute 2 inhibitors for solid and hematological malignancies, as well as license and supply agreement with Kissei Pharmaceutical Co., Ltd. to develop and commercialize Fostamatinib. The company also has a license agreement and strategic collaboration with Eli Lilly and Company to co-develop and commercialize R552 for various indications, including autoimmune and inflammatory diseases, as well as other non-central nervous system (non-CNS) disease development candidates. Rigel Pharmaceuticals, Inc. was incorporated in 1996 and is headquartered in South San Francisco, California.
How the Company Makes MoneyRigel Pharmaceuticals generates revenue through several key streams, primarily from the commercialization of its approved therapies. The company earns money by selling its marketed drugs, which include treatments for specific hematologic conditions. Additionally, Rigel may receive milestone payments and royalties from partnerships with larger pharmaceutical companies that involve co-development or licensing agreements for its drug candidates. Research and development collaborations also contribute to its revenue, allowing Rigel to leverage its technology and expertise while sharing costs and risks with partners. The success of its clinical trials and the subsequent approval of new therapies are critical factors influencing its earnings potential.

Rigel Earnings Call Summary

Earnings Call Date:Aug 05, 2025
(Q2-2025)
|
% Change Since: 63.00%|
Next Earnings Date:Nov 06, 2025
Earnings Call Sentiment Positive
The earnings call reflects a robust and positive second quarter for Rigel Pharmaceuticals, with significant revenue growth and strong commercial performance across their product portfolio. The company has raised its revenue guidance for 2025, indicating confidence in continued growth. Financial discipline has led to increased profitability, and the development pipeline shows promise. The lowlight identified is minor, involving a change in patient response status in a clinical study.
Q2-2025 Updates
Positive Updates
Record-Breaking Revenue and Growth
Rigel Pharmaceuticals achieved net product sales of more than $58 million, an increase of 76% year-over-year, marking their best quarter ever. Total revenue for the second quarter was $101.7 million, driven by their growing commercial portfolio and increased sales across all commercial products.
Strong Commercial Performance
The commercial portfolio, including TAVALISSE, GAVRETO, and REZLIDHIA, showed strong year-over-year growth. TAVALISSE net product sales increased by 52% compared to Q2 2024, GAVRETO delivered $11.8 million in net product sales (a significant growth since its late June 2024 introduction), and REZLIDHIA saw a 36% increase compared to the prior year period.
Increased Revenue Guidance for 2025
Rigel raised their total revenue guidance for 2025 to between $270 million and $280 million, up from the previous range of $200 million to $210 million. Net product sales expectations were also increased to $210 million to $220 million.
Successful Financial Discipline and Profitability
Rigel generated $59.6 million in net income in the second quarter and increased their cash balance to more than $108 million. They continue to anticipate reporting positive net income for the full year 2025.
Promising Development Pipeline
Rigel's R289, a novel dual IRAK1/4 inhibitor, is progressing well with completed enrollment in the dose escalation part of a Phase 1b clinical study. Ocadusertib, under development with Eli Lilly, is also advancing successfully.
Negative Updates
Change in Patient Response Status
In Rigel's R289 Phase 1b study, there was a change in status for one patient previously reported with a minor response, who is no longer considered a responder due to additional red cell transfusions not initially entered into the database.
Company Guidance
In the second quarter of 2025, Rigel Pharmaceuticals reported significant growth and achievements, with net product sales reaching over $58 million, marking a 76% increase year-over-year. The company's total revenue for the quarter was $101.7 million, including $42.7 million from collaborations, primarily driven by a $40 million noncash revenue recognition from its collaboration with Eli Lilly. Rigel also raised its total revenue guidance for 2025 to between $270 million and $280 million, up from the previous $200 million to $210 million, reflecting an anticipated growth rate of 45% to 52% compared to 2024. The company's net income was reported at $59.6 million, with cash reserves exceeding $108 million. Rigel's commercial portfolio, including products TAVALISSE, GAVRETO, and REZLIDHIA, contributed to these results, with TAVALISSE sales alone increasing by 52% year-over-year. The company remains focused on advancing its development pipeline, including the IRAK1/4 inhibitor R289, currently in a Phase 1b clinical study, as well as exploring strategic in-licensing and acquisition opportunities.

Rigel Financial Statement Overview

Summary
Rigel demonstrates strong revenue growth and profitability improvements, particularly in the latest TTM period. The income statement is robust with high gross and net profit margins. However, the balance sheet shows high leverage, which poses financial risk, and the return on equity is negative. Cash flow generation is strong, but operational cash efficiency could improve.
Income Statement
78
Positive
Rigel's income statement shows strong revenue growth with a 31.93% increase in TTM, indicating robust sales performance. The gross profit margin remains high at 89.64%, reflecting efficient cost management. The net profit margin improved significantly to 18.31%, showcasing enhanced profitability. However, historical volatility in EBIT and EBITDA margins suggests potential operational challenges.
Balance Sheet
55
Neutral
The balance sheet reveals a high debt-to-equity ratio of 3.29 in TTM, indicating significant leverage, which could pose financial risk. Despite this, the company has improved its equity position over time. The return on equity is negative, suggesting inefficiencies in generating returns from shareholders' equity.
Cash Flow
82
Very Positive
Rigel's cash flow statement is strong, with an impressive 85.33% growth in free cash flow in TTM, indicating improved cash generation. The free cash flow to net income ratio is healthy at 1.00, showing effective conversion of profits into cash. However, the operating cash flow to net income ratio is moderate, suggesting room for improvement in operational cash efficiency.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue267.92M179.28M116.88M120.24M149.24M108.62M
Gross Profit245.19M160.63M109.77M118.49M148.15M107.73M
EBITDA109.30M28.51M-16.98M-53.87M-11.29M-27.68M
Net Income97.82M17.48M-25.09M-58.57M-17.91M-29.74M
Balance Sheet
Total Assets206.74M163.98M117.22M134.28M167.33M110.38M
Cash, Cash Equivalents and Short-Term Investments108.38M77.32M56.93M58.21M124.97M57.33M
Total Debt61.04M59.97M60.58M41.55M30.57M39.09M
Total Liabilities124.80M160.69M145.87M147.90M136.95M76.35M
Stockholders Equity81.93M3.29M-28.64M-13.62M30.37M34.03M
Cash Flow
Free Cash Flow66.15M31.43M-20.74M-74.21M5.25M-53.45M
Operating Cash Flow65.83M31.47M-5.74M-73.76M5.88M-52.19M
Investing Cash Flow-40.94M4.13M-4.30M72.78M-80.04M47.47M
Financing Cash Flow-7.47M-11.64M18.37M6.55M62.67M12.57M

Rigel Technical Analysis

Technical Analysis Sentiment
Positive
Last Price39.51
Price Trends
50DMA
22.24
Positive
100DMA
20.40
Positive
200DMA
20.51
Positive
Market Momentum
MACD
4.69
Negative
RSI
93.35
Negative
STOCH
96.69
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RIGL, the sentiment is Positive. The current price of 39.51 is above the 20-day moving average (MA) of 26.30, above the 50-day MA of 22.24, and above the 200-day MA of 20.51, indicating a bullish trend. The MACD of 4.69 indicates Negative momentum. The RSI at 93.35 is Negative, neither overbought nor oversold. The STOCH value of 96.69 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for RIGL.

Rigel Risk Analysis

Rigel disclosed 60 risk factors in its most recent earnings report. Rigel reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Rigel Peers Comparison

Overall Rating
UnderperformOutperform
Sector (64)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
74
Outperform
$679.65M7.00376.09%105.62%
64
Neutral
€6.01B18.22-2.83%2.07%0.38%-36.73%
55
Neutral
$567.58M344.74%-47.32%-26.67%
52
Neutral
$457.66M-62.49%74.95%34.25%
45
Neutral
$206.94M40.36%9.78%98.13%
43
Neutral
$271.89M-75.08%
41
Neutral
$199.69M7.36-18.12%-66.80%-157.68%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RIGL
Rigel
39.51
27.40
226.26%
HRTX
Heron Therapeutics
1.33
-0.60
-31.09%
RGNX
RegenXBio
8.82
-3.43
-28.00%
MREO
Mereo Biopharma Group Plc
1.74
-2.59
-59.82%
IVA
Inventiva
4.36
2.16
98.18%
TRDA
Entrada Therapeutics Inc
5.27
-11.26
-68.12%

Rigel Corporate Events

Executive/Board ChangesShareholder Meetings
Rigel Pharmaceuticals Approves Equity Plan Amendment
Neutral
May 23, 2025

On May 22, 2025, Rigel Pharmaceuticals, Inc. held its 2025 Annual Meeting of Stockholders, where stockholders approved an amendment to the 2018 Equity Incentive Plan, adding 700,000 shares for issuance. The plan became effective immediately upon approval. Additionally, stockholders elected directors to serve until the 2028 Annual Meeting, approved executive compensation, and ratified Ernst & Young LLP as the independent accounting firm for the fiscal year ending December 31, 2023.

The most recent analyst rating on (RIGL) stock is a Buy with a $150.00 price target. To see the full list of analyst forecasts on Rigel stock, see the RIGL Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 07, 2025