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Rigel (RIGL)
NASDAQ:RIGL
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Rigel (RIGL) AI Stock Analysis

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RIGL

Rigel

(NASDAQ:RIGL)

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Outperform 74 (OpenAI - 5.2)
Rating:74Outperform
Price Target:
$36.00
▲(11.01% Upside)
Action:Reiterated
Date:05/14/26
The score is driven primarily by the sharp financial turnaround (strong revenue growth, profitability and positive free cash flow) and a generally positive earnings outlook with maintained 2026 guidance. Offsetting factors include earnings/cash flow durability questions, mixed technical signals (negative MACD and below longer-term averages), and only moderate valuation support.
Positive Factors
Revenue & Profitability Turnaround
A ~186% TTM revenue surge together with very strong recent operating and net margins indicates durable commercial traction for Rigel’s marketed therapies. This shift from prior losses to sustained profitability supports reinvestment in sales, R&D and disciplined BD over the next 2–6 months.
Negative Factors
Earnings Quality Mismatch
Operating cash flow materially lags reported profitability, suggesting earnings are influenced by non-cash items or timing. If cash conversion weakens in tougher quarters, reported profits may not translate to free cash for operations or BD, challenging sustainability of margins and distributions.
Read all positive and negative factors
Positive Factors
Negative Factors
Revenue & Profitability Turnaround
A ~186% TTM revenue surge together with very strong recent operating and net margins indicates durable commercial traction for Rigel’s marketed therapies. This shift from prior losses to sustained profitability supports reinvestment in sales, R&D and disciplined BD over the next 2–6 months.
Read all positive factors

Rigel (RIGL) vs. SPDR S&P 500 ETF (SPY)

Rigel Business Overview & Revenue Model

Company Description
Rigel Pharmaceuticals, Inc., a biotechnology company, discovers and develops small molecule drugs to treat hematologic disorders, cancer, and rare immune diseases. The company offers Tavalisse, an oral spleen tyrosine kinase inhibitor for the trea...
How the Company Makes Money
Rigel makes money primarily from (1) net product sales of TAVALISSE in the United States, where it commercializes the drug and recognizes revenue from sales to wholesalers/specialty distributors and other customers, net of typical biopharma deduct...

Rigel Earnings Call Summary

Earnings Call Date:May 05, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Aug 11, 2026
Earnings Call Sentiment Positive
The call conveys a generally positive commercial and strategic outlook: strong top-line product growth (26% YoY overall; 31% YoY for TAVALISSE and REZLIDHIA), clear 2026 guidance and a pathway to full-year profitability, alongside promising early clinical data for R289 and expanded international partner revenues. Offsetting risks include rising operating expenses, a modest decline in quarterly net income and cash, seasonal Q1 reimbursement headwinds, a slower-growing GAVRETO franchise, and the termination of the Lilly collaboration for the RIPK1 asset (creating program-level uncertainty). On balance, the highlights—robust product sales growth, maintained guidance, pipeline progress and improved financing flexibility—outweigh the lowlights.
Positive Updates
Strong Quarterly Net Product Sales Growth
Net product sales of $54.9M in Q1 2026, up 26% year-over-year (+$11.3M vs Q1 2025), driven by across‑portfolio strength and improving demand in March.
Negative Updates
Decline in Quarterly Net Income
Net income was $8.7M in Q1 2026, down from $11.4M in Q1 2025 (≈23.7% decrease year-over-year), reflecting higher operating costs despite revenue growth.
Read all updates
Q1-2026 Updates
Negative
Strong Quarterly Net Product Sales Growth
Net product sales of $54.9M in Q1 2026, up 26% year-over-year (+$11.3M vs Q1 2025), driven by across‑portfolio strength and improving demand in March.
Read all positive updates
Company Guidance
Management reiterated 2026 guidance for total revenues of $275–$290 million, comprising net product sales of $255–$265 million and contract revenues of $20–$25 million, and affirmed their expectation to deliver positive net income for the full year. In Q1 they reported total revenue of $58.8M (net product sales $54.9M, +26% YoY) including TAVALISSE $37.3M (+31%), GAVRETO $9.6M (+7%) and REZLIDHIA $8.0M (+31%), plus $3.9M collaboration revenue; net product sales were recorded net of $20.5M of discounts/allowances. Q1 cost of product sales was ~$4.6M, total costs and expenses were $46.9M (vs. $40.6M prior year), income before taxes $11.7M and net income $8.7M (vs. $11.4M). Balance sheet and financing items noted: cash, cash equivalents and short‑term investments of $146.7M (down from $155.0M at 12/31/25), repayment of a $40M term loan and establishment of a $40M revolving credit facility (option to increase to $60M) with $8M drawn; guidance excludes any assumed revenues from the Lilly collaboration.

Rigel Financial Statement Overview

Summary
Strong turnaround with rapid TTM revenue growth (~186%), very strong recent profitability, and improved balance sheet resilience (low recent debt-to-equity). Offsetting this is high multi-year volatility (recent profits following prior losses/negative equity) and cash flow quality concerns (operating cash flow well below net income).
Income Statement
82
Very Positive
Balance Sheet
74
Positive
Cash Flow
76
Positive
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue299.77M294.28M179.28M116.88M120.24M149.24M
Gross Profit279.95M274.66M160.63M109.77M118.49M148.15M
EBITDA131.28M131.56M28.51M-16.98M-53.87M-11.29M
Net Income364.23M367.02M17.48M-25.09M-58.57M-17.91M
Balance Sheet
Total Assets504.61M513.59M163.98M117.22M134.28M167.33M
Cash, Cash Equivalents and Short-Term Investments146.68M154.96M77.32M56.93M58.21M124.97M
Total Debt45.72M53.30M59.97M60.58M41.55M30.57M
Total Liabilities104.71M122.11M160.69M145.87M147.90M136.95M
Stockholders Equity399.90M391.48M3.29M-28.64M-13.62M30.37M
Cash Flow
Free Cash Flow79.27M75.66M31.07M-20.74M-74.21M5.25M
Operating Cash Flow79.27M75.66M31.47M-5.74M-73.76M5.88M
Investing Cash Flow-89.79M-92.36M4.13M-4.30M72.78M-80.04M
Financing Cash Flow-10.80M601.00K-11.64M18.37M6.55M62.67M

Rigel Technical Analysis

Technical Analysis Sentiment
Positive
Last Price32.43
Price Trends
50DMA
30.43
Positive
100DMA
36.15
Negative
200DMA
33.58
Negative
Market Momentum
MACD
0.62
Negative
RSI
65.31
Neutral
STOCH
91.81
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RIGL, the sentiment is Positive. The current price of 32.43 is above the 20-day moving average (MA) of 28.40, above the 50-day MA of 30.43, and below the 200-day MA of 33.58, indicating a neutral trend. The MACD of 0.62 indicates Negative momentum. The RSI at 65.31 is Neutral, neither overbought nor oversold. The STOCH value of 91.81 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for RIGL.

Rigel Risk Analysis

Rigel disclosed 59 risk factors in its most recent earnings report. Rigel reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Rigel Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
74
Outperform
$536.75M14.38147.03%47.61%854.73%
55
Neutral
$990.56M-149.66-18.64%123.12%86.10%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$310.20M-1.33-35.74%146.03%-0.87%
48
Neutral
$295.71M-1.22-232.50%-43.96%-78.31%
45
Neutral
$379.61M-3.56-486.41%395.85%21.44%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RIGL
Rigel
29.01
9.31
47.26%
LXRX
Lexicon Pharmaceuticals
2.23
1.67
298.21%
VSTM
Verastem
4.32
-3.43
-44.26%
RGNX
RegenXBio
5.72
-4.07
-41.57%
BCYC
Bicycle Therapeutics
4.45
-4.18
-48.44%

Rigel Corporate Events

Business Operations and StrategyProduct-Related Announcements
Rigel Secures Global Rights to VEPPANU Breast Cancer Therapy
Positive
May 12, 2026
On May 11, 2026, Rigel Pharmaceuticals entered into a license agreement with Arvinas and Pfizer to obtain exclusive worldwide rights to develop, manufacture and commercialize VEPPANU (vepdegestrant) and related products, consolidating Rigel’...
Business Operations and Strategy
Rigel Regains Rights as Eli Lilly Ends Collaboration
Negative
Apr 21, 2026
On April 16, 2026, Rigel Pharmaceuticals received notice that Eli Lilly is terminating their 2021 license and collaboration agreement, which will become effective June 15, 2026. The deal had granted Lilly exclusive global rights to develop and com...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 14, 2026