Record-Breaking Revenue and Growth
Rigel Pharmaceuticals achieved net product sales of more than $58 million, an increase of 76% year-over-year, marking their best quarter ever. Total revenue for the second quarter was $101.7 million, driven by their growing commercial portfolio and increased sales across all commercial products.
Strong Commercial Performance
The commercial portfolio, including TAVALISSE, GAVRETO, and REZLIDHIA, showed strong year-over-year growth. TAVALISSE net product sales increased by 52% compared to Q2 2024, GAVRETO delivered $11.8 million in net product sales (a significant growth since its late June 2024 introduction), and REZLIDHIA saw a 36% increase compared to the prior year period.
Increased Revenue Guidance for 2025
Rigel raised their total revenue guidance for 2025 to between $270 million and $280 million, up from the previous range of $200 million to $210 million. Net product sales expectations were also increased to $210 million to $220 million.
Successful Financial Discipline and Profitability
Rigel generated $59.6 million in net income in the second quarter and increased their cash balance to more than $108 million. They continue to anticipate reporting positive net income for the full year 2025.
Promising Development Pipeline
Rigel's R289, a novel dual IRAK1/4 inhibitor, is progressing well with completed enrollment in the dose escalation part of a Phase 1b clinical study. Ocadusertib, under development with Eli Lilly, is also advancing successfully.