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Rani Therapeutics Holdings, Inc. Class A (RANI)
:RANI
RESEARCH TOOLSreports
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Rani Therapeutics Holdings
(NASDAQ:RANI)
Rating:32Underperform
Price Target:―
Positive Factors
Partnerships
Rani entered into a research agreement with Chugai Pharmaceutical Co., indicating a significant collaboration.
Product Development
RaniPill delivery demonstrated comparable bioavailability to the subQ route of delivery for both molecules studied.
Negative Factors
Financial Performance
Rani Therapeutics reported a net loss of ($12.7M) and ended the period with $15.9M in cash, indicating the company will require additional capital.
Risk Factors
Risks include negative Phase 2 data, negative clinical readouts with other candidates, and failure to achieve approvals for key pipeline projects.
Rani Therapeutics Holdings (RANI) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$33.85M
Dividend YieldN/A
Average Volume (3M)305.34K
Price to Earnings (P/E)―
Beta (1Y)0.59
Revenue GrowthN/A
EPS Growth20.85%
CountryUS
Employees105
SectorHealthcare
Sector Strength39
IndustryBiotechnology
Share Statistics
EPS (TTM)-0.22
Shares Outstanding39,252,520
10 Day Avg. Volume308,228
30 Day Avg. Volume305,339
Financial Highlights & Ratios
PEG Ratio1.99
Price to Book (P/B)3.81
Price to Sales (P/S)0.00
P/FCF Ratio-2.92
Enterprise Value/Market Cap4.25
Enterprise Value/Revenue19.02
Enterprise Value/Gross Profit283.49
Enterprise Value/Ebitda-0.71
Forecast
1Y Price Target
$7.00Price Target Upside1196.30% Upside
Rating ConsensusModerate Buy
Number of Analyst Covering2
Rani Therapeutics Holdings Business Overview & Revenue Model
Company DescriptionRani Therapeutics Holdings (RANI) is a healthcare company focused on developing innovative oral biologics utilizing its proprietary RaniPill technology. The company operates within the biotechnology and pharmaceutical sectors, offering a unique solution for the oral delivery of biologics, which are traditionally administered via injection. Rani's core product, the RaniPill capsule, is designed to deliver large-molecule drugs through the gastrointestinal tract, thereby improving patient compliance and expanding the potential market for biologic therapies.
How the Company Makes MoneyRani Therapeutics Holdings generates revenue primarily through the development and commercialization of its RaniPill technology. The company earns money by partnering with pharmaceutical companies to develop oral versions of existing injectable biologics. These partnerships often involve research and development collaborations, licensing agreements, and milestone payments. Rani may also receive royalties from the sale of drugs developed using its technology. Additionally, the company may engage in direct sales of its RaniPill technology or related products once they receive regulatory approval and enter the market.
Rani Therapeutics Holdings Earnings Call Summary
Earnings Call Date:May 13, 2025
(Q4-2024)
| % Change Since: 12.50%|
Next Earnings Date:Aug 07, 2025
Earnings Call Sentiment Neutral
The earnings call highlighted significant advancements in Rani's technology and pipeline, particularly in the obesity treatment market, supported by strategic partnerships and successful preclinical data. However, financial challenges remain, as evidenced by decreased cash reserves and a substantial net loss for the year.Q4-2024 Updates
Positive Updates
Advancements in RaniPill Technology
The RaniPill technology, designed for oral delivery of biologics, has shown success in preclinical and clinical trials, achieving high bioavailability for 19 molecules and completing three Phase 1 studies with no serious adverse events.
Progress in Obesity Treatment Pipeline
Rani made significant advancements in their obesity treatment pipeline, particularly with RT-114 and semaglutide programs, expecting the obesity market to reach $100 billion by 2030.
Successful Preclinical Data for RT-116
RT-116 demonstrated comparable pharmacokinetics and weight loss to subcutaneous administration with a relative bioavailability of 107% in preclinical studies.
RT-114 Preclinical Success
RT-114 showed higher Cmax and earlier Tmax than subcutaneous PG-102, with a relative bioavailability of 111% and equivalent weight loss in canine studies.
Strategic Partnership with ProGen
Rani entered a co-development agreement with ProGen for RT-114, combining ProGen's GLP-1/GLP-2 molecule with RaniPill technology.
Negative Updates
Decreased Financial Reserves
Cash, cash equivalents, and marketable securities decreased from $48.5 million in 2023 to $27.6 million in 2024, with funding expected to last into Q3 2025.
Impairment Loss
Rani recorded an impairment loss of $3.7 million related to certain manufacturing property and equipment.
Net Loss for 2024
The net loss for 2024 was $56.6 million, including an impairment loss of $3.7 million and stock-based compensation expense of $16 million.
Company Guidance
During Rani Therapeutics' fourth quarter and full year 2024 earnings call, guidance was provided on the company's strategic focus and financial outlook. The company emphasized advancements in its RaniPill platform, highlighting its application in obesity and immunology spaces. Rani plans to further develop its RT-114 and semaglutide programs, with RT-114 moving into clinical trials by mid-2025. Financially, Rani reported a net loss of $56.6 million for the full year, an improvement from $67.9 million in 2023, partly due to cost containment measures. The company ended the year with $27.6 million in cash and expects this to fund operations into the third quarter of 2025. Additionally, Rani is exploring partnership opportunities to leverage its platform technology across multiple indications.Rani Therapeutics Holdings Financial Statement Overview
Summary
Rani Therapeutics Holdings shows weak financial performance with consistent net losses and no revenue. The balance sheet is under stress with high leverage, and cash flow issues persist, indicating significant operational and financial challenges.Income Statement
Rani Therapeutics Holdings has consistently reported zero revenue over the past three years, indicating a lack of sales activity or product commercialization. The company has also faced persistent net losses, which have slightly improved from $63.34 million in 2022 to $30.02 million in 2024. EBIT and EBITDA margins remain negative, reflecting ongoing operational challenges.15
Very Negative
Balance Sheet
The company's balance sheet shows a weak equity base with stockholders' equity consistently declining each year. The debt-to-equity ratio is high due to significant liabilities compared to equity, raising concerns over financial leverage. The equity ratio is low, indicating a heavy reliance on debt financing. These factors may pose financial risks if the company cannot achieve profitability or secure additional funding.30
Negative
Cash Flow
Rani Therapeutics Holdings has consistently experienced negative operating and free cash flows, indicating cash burn issues. Despite some reduction in free cash flow deficits, the company still struggles to generate positive cash flow from operations. The operating cash flow to net income ratio remains negative, highlighting challenges in converting sales into cash.20
Very Negative
| Breakdown | TTM | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 | Dec 2020 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 1.03M | 1.03M | 0.00 | 0.00 | 2.72M | 462.00K |
| Gross Profit | 507.00K | 1.03M | -822.00K | -1.31M | 2.72M | 462.00K |
| EBITDA | -49.30M | -50.52M | -65.28M | -60.89M | -52.08M | -15.96M |
| Net Income | -29.80M | -30.02M | -33.97M | -63.34M | -53.09M | -16.70M |
Balance Sheet | ||||||
| Total Assets | 24.13M | 36.63M | 57.92M | 108.03M | 124.21M | 79.42M |
| Cash, Cash Equivalents and Short-Term Investments | 15.85M | 27.64M | 48.54M | 98.48M | 117.45M | 73.06M |
| Total Debt | 19.75M | 29.71M | 30.10M | 30.21M | 0.00 | 3.77M |
| Total Liabilities | 29.47M | 33.14M | 32.47M | 34.02M | 2.64M | 192.75M |
| Stockholders Equity | -3.06M | 1.99M | 12.87M | 36.85M | 47.41M | -113.34M |
Cash Flow | ||||||
| Free Cash Flow | -34.54M | -35.76M | -52.47M | -48.13M | -32.75M | -16.16M |
| Operating Cash Flow | -34.24M | -35.50M | -51.24M | -46.52M | -32.24M | -14.96M |
| Investing Cash Flow | 27.74M | 19.81M | 29.86M | -72.44M | -506.00K | -1.20M |
| Financing Cash Flow | 9.73M | 13.59M | 233.00K | 29.00M | 77.15M | 72.68M |
Rani Therapeutics Holdings Technical Analysis
Neutral
0.54
Price Trends
0.69
Negative
1.06
Negative
1.50
Negative
Market Momentum
-0.04
Negative
43.33
Neutral
34.27
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RANI, the sentiment is Neutral. The current price of 0.54 is above the 20-day moving average (MA) of 0.53, below the 50-day MA of 0.69, and below the 200-day MA of 1.50, indicating a neutral trend. The MACD of -0.04 indicates Negative momentum. The RSI at 43.33 is Neutral, neither overbought nor oversold. The STOCH value of 34.27 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for RANI.
Rani Therapeutics Holdings Risk Analysis
Rani Therapeutics Holdings disclosed 102 risk factors in its most recent earnings report. Rani Therapeutics Holdings reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
Rani Therapeutics Holdings Peers Comparison
Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
52 Neutral | $7.53B | 0.32 | -61.76% | 2.28% | 16.60% | 1.56% | |
48 Neutral | $85.45M | ― | -78.93% | ― | -70.15% | ― | |
45 Neutral | $81.76M | ― | -245.59% | ― | 27.36% | 23.82% | |
45 Neutral | $81.76M | ― | -245.59% | ― | 27.36% | 23.82% | |
44 Neutral | $87.15M | ― | -55.14% | ― | -99.43% | -69.40% | |
43 Neutral | $94.35M | ― | -44.89% | ― | ― | 64.71% | |
40 Neutral | $47.63M | ― | -127.99% | ― | ― | 37.54% | |
32 Underperform | $33.85M | ― | -1372.59% | ― | ― | 20.85% |
* Healthcare Sector Average
Performance Comparison
RANI
Rani Therapeutics Holdings
0.54
-3.06
-85.00%
CRBP
Corbus Pharmaceuticals
7.71
-43.26
-84.87%
ADVM
Adverum Biotechnologies
2.28
-4.90
-68.25%
IGMS
IGM Biosciences
1.36
-5.34
-79.70%
IGMS
IGM Biosciences
1.36
-5.34
-79.70%
ADAG
Adagene
1.85
-0.97
-34.40%
TCRX
TScan Therapeutics
1.51
-4.31
-74.05%
Rani Therapeutics Holdings Corporate Events
Executive/Board Changes
Rani Therapeutics Board Restructures After DeBuono’s Retirement
Neutral
Apr 30, 2025
On April 24, 2025, Laureen DeBuono retired from the Board of Directors of Rani Therapeutics Holdings, Inc., with her decision not stemming from any disagreements with the company. Her departure led to a reconstitution of the Board’s committees, with new chairs and members appointed to the Audit, Compensation, and Nominating and Corporate Governance Committees.
Spark’s Take on RANI Stock
According to Spark, TipRanks’ AI Analyst, RANI is a Underperform.
Rani Therapeutics Holdings’ overall stock score reflects significant financial struggles with no revenue and consistent net losses. The technical analysis shows a bearish trend, and the valuation is challenging with a negative P/E ratio. Strategic advancements in technology and potential partnerships are positive but are overshadowed by financial constraints and high leverage.
To see Spark’s full report on RANI stock, click here.
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.