Advancements in RaniPill Technology
The RaniPill technology, designed for oral delivery of biologics, has shown success in preclinical and clinical trials, achieving high bioavailability for 19 molecules and completing three Phase 1 studies with no serious adverse events.
Progress in Obesity Treatment Pipeline
Rani made significant advancements in their obesity treatment pipeline, particularly with RT-114 and semaglutide programs, expecting the obesity market to reach $100 billion by 2030.
Successful Preclinical Data for RT-116
RT-116 demonstrated comparable pharmacokinetics and weight loss to subcutaneous administration with a relative bioavailability of 107% in preclinical studies.
RT-114 Preclinical Success
RT-114 showed higher Cmax and earlier Tmax than subcutaneous PG-102, with a relative bioavailability of 111% and equivalent weight loss in canine studies.
Strategic Partnership with ProGen
Rani entered a co-development agreement with ProGen for RT-114, combining ProGen's GLP-1/GLP-2 molecule with RaniPill technology.