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PainReform (PRFX)
NASDAQ:PRFX
US Market
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PainReform (PRFX) AI Stock Analysis

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PRFX

PainReform

(NASDAQ:PRFX)

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Neutral 42 (OpenAI - 5.2)
Rating:42Neutral
Price Target:
$1.50
▲(87.50% Upside)
Action:Reiterated
Date:04/30/26
The score is driven down primarily by very weak financial performance (minimal revenue, large ongoing losses, and continued cash burn). Technicals also remain unfavorable with a clear downtrend and negative momentum, despite oversold readings. Valuation provides limited support because the company is loss-making (negative P/E) and no dividend yield is available.
Positive Factors
Low leverage / balance sheet strength
Very low reported debt materially reduces near-term solvency risk and gives management optionality to pursue commercial or clinical milestones without immediate pressure from creditors. Over a 2–6 month horizon this durable low-leverage profile supports runway flexibility versus highly leveraged peers.
Negative Factors
Minimal revenue and persistent net losses
Tiny reported revenue coupled with large net losses (about -$4.8M in 2025 after -$14.6M in 2024) indicates the core business is far from commercial scale. Sustained negative margins materially impair the firm’s ability to self‑fund growth and represent a durable fundamental constraint until revenue meaningfully ramps.
Read all positive and negative factors
Positive Factors
Negative Factors
Low leverage / balance sheet strength
Very low reported debt materially reduces near-term solvency risk and gives management optionality to pursue commercial or clinical milestones without immediate pressure from creditors. Over a 2–6 month horizon this durable low-leverage profile supports runway flexibility versus highly leveraged peers.
Read all positive factors

PainReform (PRFX) vs. SPDR S&P 500 ETF (SPY)

PainReform Business Overview & Revenue Model

Company Description
PRF Technologies Ltd., a clinical stage specialty pharmaceutical company, engages in the development of therapeutics that provides an extended period of post-surgical pain relief in Israel. It engages in developing PRF-110, a viscous clear oil-bas...

PainReform Financial Statement Overview

Summary
Financials remain very weak: revenue is negligible (~$17K in 2025) with deeply negative profitability and multi-million-dollar net losses, alongside ongoing negative operating cash flow/free cash flow. The main offset is low leverage/minimal debt, which reduces near-term solvency risk, but persistent losses and cash burn keep the score near the lower bound.
Income Statement
12
Very Negative
Balance Sheet
58
Neutral
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.0017.00K0.000.0086.00K0.00
Gross Profit0.00-827.00K-16.00K-15.00K71.00K
EBITDA-3.94M-4.21M-14.55M-9.57M-8.76M-7.20M
Net Income-4.09M-4.84M-14.59M-9.34M-8.79M-7.25M
Balance Sheet
Total Assets11.16M12.00M4.53M9.93M12.33M19.07M
Cash, Cash Equivalents and Short-Term Investments3.48M4.17M4.26M8.03M4.10M16.54M
Total Debt56.00K21.00K45.00K86.00K0.000.00
Total Liabilities2.72M2.71M2.70M2.69M1.31M991.00K
Stockholders Equity8.44M8.54M1.82M7.24M11.02M18.08M
Cash Flow
Free Cash Flow-5.96M-3.96M-12.63M-6.69M-6.46M-6.60M
Operating Cash Flow-5.96M-3.96M-12.62M-6.68M-6.46M-6.55M
Investing Cash Flow-51.00K-982.00K-13.00K5.99M-6.01M-50.00K
Financing Cash Flow6.70M3.82M8.86M4.62M0.007.48M

PainReform Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.80
Price Trends
50DMA
2.25
Negative
100DMA
2.90
Negative
200DMA
4.57
Negative
Market Momentum
MACD
-0.23
Positive
RSI
25.78
Positive
STOCH
11.98
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PRFX, the sentiment is Negative. The current price of 0.8 is below the 20-day moving average (MA) of 1.96, below the 50-day MA of 2.25, and below the 200-day MA of 4.57, indicating a bearish trend. The MACD of -0.23 indicates Positive momentum. The RSI at 25.78 is Positive, neither overbought nor oversold. The STOCH value of 11.98 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for PRFX.

PainReform Risk Analysis

PainReform disclosed 46 risk factors in its most recent earnings report. PainReform reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

PainReform Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
$42.14M-7.07%75.39%
44
Neutral
$5.35M
44
Neutral
$15.33M-0.79-63.82%
42
Neutral
$1.33M
$3.72M-0.40-9999.00%92.53%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PRFX
PainReform
1.53
-8.22
-84.31%
CPHI
China Pharma Holdings
0.74
-1.60
-68.21%
RDHL
RedHill Biopharma
0.93
-0.97
-50.89%
COSM
Cosmos Holdings
0.29
-0.15
-34.45%
SHPH
Shuttle Pharmaceuticals Holdings, Inc.
0.62
-4.40
-87.65%

PainReform Corporate Events

PRF Technologies Secures Up to $10 Million Standby Equity Facility With Yorkville
May 7, 2026
On May 7, 2026, PRF Technologies Ltd. entered into a Standby Equity Purchase Agreement with Yorkville affiliate YA II PN, LTD., giving the company the right, but not the obligation, to sell up to $10 million of its ordinary shares over 36 months. ...
PRF Technologies Wins FDA IND Clearance for OcuRing-K Phase II Cataract Trial
Apr 28, 2026
PRF Technologies Ltd., a Nasdaq-listed clinical-stage specialty pharmaceutical and technology company, develops extended-release drug-delivery solutions for post-operative pain and operates the DeepSolar platform for AI-driven energy optimization ...
PRF Technologies Posts 2025 Results as LayerBio and DeepSolar Deals Drive Dual-Platform Pivot
Mar 27, 2026
On March 27, 2026, PRF Technologies issued a year-end 2025 update detailing a strategic pivot into dual platforms in healthcare and renewable-energy analytics. The company reported a sharply reduced annual net loss of about $4.8 million versus $14...
PRF Technologies Taps Blade Ranger to Drive Utility-Scale DeepSolar Deals
Mar 17, 2026
On March 16, 2026, Israel-based PRF Technologies entered a commercial collaboration agreement with Blade Ranger Ltd. to drive large-scale adoption of its DeepSolar AI analytics platform across utility-scale solar portfolios. Under the deal, Blade ...
PRF Technologies Reshapes Top Leadership With New Interim CEO and Permanent CFO
Mar 3, 2026
PRF Technologies Ltd., formerly known as PainReform, is an Israel-based healthcare company focused on developing technologies and products in the medical and biopharmaceutical space. The company targets global markets through its innovation-driven...
PRF Technologies’ DeepSolar Lands First Commercial Due Diligence Deal with EDF in Israel
Feb 18, 2026
On February 18, 2026, PRF Technologies announced that its DeepSolar unit signed its first commercial technical due diligence engagement with a subsidiary of EDF Group’s Israeli renewable-energy arm, covering an operational utility-scale sola...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 30, 2026