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BiomX (PHGE)
:PHGE
US Market

BiomX (PHGE) AI Stock Analysis

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BiomX

(NYSE MKT:PHGE)

Rating:44Neutral
Price Target:
BiomX's overall score is driven by significant financial challenges, including negative revenues and high leverage, which are key risks. However, recent positive trial results and funding announcements provide potential for future growth and improvement.
Positive Factors
Clinical Trials
BX211 led to a statistically significant and sustained reduction in ulcer size, with statistical significance observed at week 12.
Innovation
Bacteriophages could help overcome challenges by directly targeting and killing bacteria, including antibiotic-resistant strains, which is promising for diabetic foot osteomyelitis treatment.
Regulatory Progress
Key upcoming milestones for the company include initiating a Phase 2/3 trial and meeting with regulatory authorities to present data collected on real-world evidence in CF patients.
Negative Factors
Investor Sentiment
Investor sentiment was negative, which is likely due to the p-values for the key endpoints.

BiomX (PHGE) vs. SPDR S&P 500 ETF (SPY)

BiomX Business Overview & Revenue Model

Company DescriptionBiomX Inc., a clinical-stage microbiome company, develops products using natural and engineered phage technologies designed to target and kill specific harmful bacteria. It targets bacteria that affect the appearance of skin, as well as chronic diseases, such as inflammatory bowel diseases (IBD), primary sclerosing cholangitis (PSC), cystic fibrosis (CF), atopic dermatitis, and colorectal cancer (CRC). It is developing BX004, a phage therapy for CF patients with chronic Pseudomonas aeruginosa respiratory infections that is in Phase 1b/2a clinical trials. The company's pipeline products also include BX005, a topical phage cocktail, which is in Phase 1/2 clinical study that targets Staphylococcus aureus (S. aureus), a bacteria associated with the manifestation of the disease; and BX003, an orally administered phage cocktail, which is in Phase 1b/2a that targets a bacterial target present in the gut of IBD and PSC patients. In addition, the company engages in the provision of colorectal cancer program that utilizes engineered phage with various payloads, which are administered intravenously to target Fusobacterium nucleatum bacteria residing within the tumor microenvironment. BiomX Inc. was founded in 2015 and is headquartered in Ness Ziona, Israel.
How the Company Makes MoneyBiomX primarily makes money through research and development collaborations, grants, and potential future product sales. The company engages in partnerships with pharmaceutical and biotechnology companies to co-develop phage therapies, which can provide upfront payments, milestone payments, and royalties. Additionally, BiomX may receive funding from governmental or non-profit grants to support its research initiatives. As its products progress through clinical trials and potentially reach the market, revenue from sales of approved therapies will become a significant source of income.

BiomX Financial Statement Overview

Summary
BiomX faces significant financial challenges with persistent negative revenues and high operating losses. The balance sheet shows high leverage, and the cash flow statements indicate a reliance on external financing. Despite some improvements in net income and stockholders' equity, the company's overall financial health is strained.
Income Statement
15
Very Negative
BiomX has consistently reported negative revenues and gross profit over the years, indicating significant challenges in generating income. The company has also faced substantial net losses, although a notable improvement in net income was seen in 2024. The lack of revenue growth and negative margins, such as EBIT and EBITDA, highlight ongoing difficulties in achieving profitability.
Balance Sheet
35
Negative
The company's balance sheet shows high leverage, with a significant amount of total debt relative to equity, resulting in a concerning debt-to-equity ratio. However, the equity ratio indicates that a reasonable portion of the company's assets are financed by equity. Despite recent improvements in stockholders' equity, the overall financial stability remains a concern due to the high liabilities.
Cash Flow
25
Negative
BiomX's cash flow statements reflect ongoing negative free cash flow, indicating cash outflows from operations and investments. While there is a trend of securing financing to support cash needs, this reliance on external funding poses risks. The operating cash flow to net income ratio shows significant cash outflows relative to earnings, underscoring financial pressure.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
0.00-357.00K-134.00K0.000.00
Gross Profit
0.00-1.23M-2.65M-2.56M-2.18M
EBIT
0.00-27.68M-27.22M35.46M-30.26M
EBITDA
-13.13M-22.82M-23.65M-32.89M-27.90M
Net Income Common Stockholders
17.73M-26.17M-28.32M-36.23M-29.91M
Balance SheetCash, Cash Equivalents and Short-Term Investments
17.81M15.86M33.33M62.10M56.33M
Total Assets
43.23M25.03M45.53M77.99M70.36M
Total Debt
9.58M15.09M19.36M20.02M5.89M
Net Debt
-7.27M-772.00K-11.97M-42.08M-30.58M
Total Liabilities
19.09M21.95M24.49M30.45M12.89M
Stockholders Equity
24.15M3.08M21.04M47.53M57.47M
Cash FlowFree Cash Flow
-37.01M-21.34M-29.20M-31.25M-25.46M
Operating Cash Flow
-36.98M-21.29M-29.09M-27.57M-24.45M
Investing Cash Flow
715.00K1.95M-2.11M16.17M-10.86M
Financing Cash Flow
38.37M2.90M292.00K37.28M134.00K

BiomX Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.53
Price Trends
50DMA
0.57
Negative
100DMA
0.67
Negative
200DMA
0.83
Negative
Market Momentum
MACD
-0.01
Positive
RSI
42.24
Neutral
STOCH
48.11
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PHGE, the sentiment is Negative. The current price of 0.53 is below the 20-day moving average (MA) of 0.57, below the 50-day MA of 0.57, and below the 200-day MA of 0.83, indicating a bearish trend. The MACD of -0.01 indicates Positive momentum. The RSI at 42.24 is Neutral, neither overbought nor oversold. The STOCH value of 48.11 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for PHGE.

BiomX Risk Analysis

BiomX disclosed 72 risk factors in its most recent earnings report. BiomX reported the most risks in the “Tech & Innovation” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BiomX Peers Comparison

Overall Rating
UnderperformOutperform
Sector (53)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
53
Neutral
$5.24B3.07-43.58%2.80%16.87%-0.11%
46
Neutral
$22.18M-2951.24%14.17%28.26%
45
Neutral
$12.64M-83.92%-67.87%0.40%
44
Neutral
$14.30M-68.18%45.24%
44
Neutral
$17.12M-92.35%-85.48%45.13%
43
Neutral
$22.98M-27.00%1904.43%93.72%
34
Underperform
$11.77M-208.72%56.38%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PHGE
BiomX
0.53
-3.04
-85.15%
CRIS
Curis
1.92
-8.90
-82.26%
CLRB
Cellectar Biosciences
0.25
-2.95
-92.19%
ABVC
ABVC BioPharma
1.19
0.12
11.21%
BOLT
Bolt Biotherapeutics
0.32
-0.44
-57.89%
SABS
SAB Biotherapeutics
1.71
-1.13
-39.79%

BiomX Earnings Call Summary

Earnings Call Date:May 15, 2025
(Q1-2025)
|
% Change Since: -3.64%|
Next Earnings Date:Aug 14, 2025
Earnings Call Sentiment Positive
The earnings call highlighted significant progress with positive clinical trial results and secured financing, although there was an increase in R&D expenses. Overall, the sentiment of the call is optimistic with a focus on future opportunities.
Q1-2025 Updates
Positive Updates
Positive Phase 2 Trial Results for BX211
BiomX announced positive top-line results from the Phase 2 trial evaluating BX211 for diabetic foot osteomyelitis, demonstrating safety and tolerability, with significant improvement in ulcer size and depth.
$12 Million Financing Secured
BiomX announced a $12 million financing, providing a financial runway into the first quarter of 2026, supporting ongoing clinical trials.
Reduced Net Loss
Net loss reduced to $7.7 million for Q1 2025, compared to $17.3 million in Q1 2024, primarily due to changes in warrant fair value.
Negative Updates
Increased Research and Development Expenses
R&D expenses increased to $5.3 million in Q1 2025 from $4.1 million in Q1 2024, due to preparations for clinical trials and increased operational costs.
Company Guidance
During the BiomX First Quarter 2025 Financial Results Conference Call, the company provided significant guidance on its clinical and financial milestones. BiomX reported a positive top-line result from its Phase 2 trial of BX211 in diabetic foot osteomyelitis, demonstrating safety and efficacy with a statistically significant reduction in ulcer size and depth. The company is planning to advance BX211 to a potential Phase 2-3 trial pending regulatory feedback and is exploring funding opportunities, with approximately $40 million in non-diluted funding from the U.S. Defense Health Agency. For BX004, a Phase 2b trial in cystic fibrosis is expected to report top-line results in Q1 2026, with a current cash runway into the first quarter of 2026 after a $12 million financing and warrant exercise. Additionally, the company highlighted a net loss reduction to $7.7 million in Q1 2025 from $17.3 million in Q1 2024, attributed to changes in warrant valuations. Research and development expenses rose to $5.3 million due to clinical trial preparations and increased costs following an acquisition.

BiomX Corporate Events

Product-Related AnnouncementsBusiness Operations and Strategy
BiomX Announces Positive Phase 2 Trial Results
Positive
Mar 31, 2025

On March 31, 2025, BiomX Inc. announced positive results from its Phase 2 trial of BX211 for treating Diabetic Foot Osteomyelitis (DFO) associated with Staphylococcus aureus. The trial demonstrated that BX211 was safe, well-tolerated, and produced statistically significant reductions in ulcer size and depth compared to placebo. These findings highlight the potential of phage therapy in addressing serious bacterial infections and reducing the need for amputations in diabetic patients. Following these results, BiomX plans to proceed with a Phase 2/3 trial pending FDA feedback.

Private Placements and FinancingBusiness Operations and Strategy
BiomX Announces $12M Funding for BX004 Study
Positive
Feb 27, 2025

On February 25, 2025, BiomX Inc. announced a securities purchase agreement involving a registered direct offering and concurrent private placement, expected to generate approximately $12 million in gross proceeds. The funds will support the Phase 2b clinical study of BX004, a phage cocktail for treating cystic fibrosis patients with chronic Pseudomonas aeruginosa infections, with results anticipated in Q1 2026. The offerings, led by Deerfield Management Company and the Cystic Fibrosis Foundation, are set to close around February 27, 2025, and include a reduction in exercise price for existing warrants. This strategic move aims to advance BiomX’s clinical programs and strengthen its position in the phage therapy market.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.