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BiomX (PHGE)
:PHGE
US Market

BiomX (PHGE) AI Stock Analysis

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PHGE

BiomX

(PHGE)

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Neutral 43 (OpenAI - 5.2)
Rating:43Neutral
Price Target:
$2.00
▼(-10.71% Downside)
The score is held down primarily by weak financial performance (minimal revenue, persistent losses and cash burn) and bearish technical trends (well below major moving averages with negative MACD). Offsetting factors are limited to modest balance-sheet leverage improvement and a cautiously positive clinical/regulatory outlook, though near-term liquidity needs and recent negative corporate developments keep the risk profile elevated.
Positive Factors
Regulatory clarity for BX011 (FDA feedback)
Concrete FDA guidance that defines a development pathway for BX011 materially reduces regulatory uncertainty and shortens the time and resources needed to progress to a potential Biologics License Application. This durable clarity supports prioritization of resources and increases program de-risking for the coming quarters.
Non-dilutive U.S. Defense funding supports BX011
~$40M of non-dilutive funding from Defense agencies provides substantive program financing that lessens near-term reliance on dilutive capital raises. Such strategic, non-dilutive support validates the technology's relevance to defense health priorities and sustainably underpins BX011 clinical advancement.
Improved balance-sheet leverage vs. prior year
A meaningful reduction in leverage and positive equity improve solvency resilience, lowering bankruptcy and covenant risk. This structurally enhances the company’s ability to negotiate with partners and creditors and provides more optionality to fund clinical programs over the medium term, assuming losses are managed.
Negative Factors
High cash burn and limited runway
Persistently negative operating and free cash flow with a cash balance funding operations only into Q1 2026 creates a structural financing necessity. This raises the likelihood of dilutive financings or partnership dependence, which can delay trials or force program prioritization, constraining long-term development plans.
Discontinuation of BX004 and subsidiary insolvency
Halting BX004 and an insolvency filing materially reduces pipeline breadth and clinical optionality, weakening future revenue and partnering potential. Loss of an advanced CF program and restructuring of a subsidiary are durable setbacks that may erode investor and partner confidence and increase execution risk for remaining programs.
Preferred Series Y financing raises dilution and governance risk
The preferred financing provides short-term liquidity but imposes expensive dividend obligations, near-term senior claims, and potential significant dilution via conversion and warrants. Board representation rights shift governance dynamics, creating lasting capital structure and control implications that may constrain strategic flexibility.

BiomX (PHGE) vs. SPDR S&P 500 ETF (SPY)

BiomX Business Overview & Revenue Model

Company DescriptionBiomX Inc., a clinical-stage microbiome company, develops products using natural and engineered phage technologies designed to target and kill specific harmful bacteria. It targets bacteria that affect the appearance of skin, as well as chronic diseases, such as inflammatory bowel diseases (IBD), primary sclerosing cholangitis (PSC), cystic fibrosis (CF), atopic dermatitis, and colorectal cancer (CRC). It is developing BX004, a phage therapy for CF patients with chronic Pseudomonas aeruginosa respiratory infections that is in Phase 1b/2a clinical trials. The company's pipeline products also include BX005, a topical phage cocktail, which is in Phase 1/2 clinical study that targets Staphylococcus aureus (S. aureus), a bacteria associated with the manifestation of the disease; and BX003, an orally administered phage cocktail, which is in Phase 1b/2a that targets a bacterial target present in the gut of IBD and PSC patients. In addition, the company engages in the provision of colorectal cancer program that utilizes engineered phage with various payloads, which are administered intravenously to target Fusobacterium nucleatum bacteria residing within the tumor microenvironment. BiomX Inc. was founded in 2015 and is headquartered in Ness Ziona, Israel.
How the Company Makes MoneyBiomX primarily makes money through research and development collaborations, grants, and potential future product sales. The company engages in partnerships with pharmaceutical and biotechnology companies to co-develop phage therapies, which can provide upfront payments, milestone payments, and royalties. Additionally, BiomX may receive funding from governmental or non-profit grants to support its research initiatives. As its products progress through clinical trials and potentially reach the market, revenue from sales of approved therapies will become a significant source of income.

BiomX Earnings Call Summary

Earnings Call Date:Nov 12, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Apr 01, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted significant progress in clinical trials and positive regulatory feedback which provides a strong outlook for future developments. However, financial challenges and regulatory holds present ongoing risks. Optimism in phage therapy's future and strategic plans for BX011 and BX004 suggest a cautiously positive sentiment.
Q3-2025 Updates
Positive Updates
BX004 Phase IIb Trial Progress and FDA Feedback
The BX004 program for cystic fibrosis patients showed significant progress with first patient dosing in the Phase IIb trial. Despite a clinical hold on U.S. trial sites due to a third-party nebulizer device, the European trial continues uninterrupted. FDA feedback recognized the unmet need for treatments targeting chronic Pseudomonas aeruginosa infections and provided constructive guidance for development pathways, including Phase III criteria.
Positive FDA Feedback for BX011 in Diabetic Foot Infections
The FDA provided positive feedback on the development plan for BX011 targeting Staphylococcus aureus infections in diabetic foot infections (DFI). The program aims to provide an off-the-shelf formulation with potential for dual-use in combat-related wound infections, aligning with U.S. Defense Health Agency priorities. The FDA outlined a clear pathway toward a Biologics License Application without additional nonclinical studies, supporting the commercial opportunity.
Financial Management and Reduced Expenses
Research and development expenses decreased to $6.1 million in Q3 2025 from $7.3 million in Q3 2024, attributed to workforce reduction and lower rent expenses. General and administrative expenses also decreased to $2.4 million from $3.2 million. BiomX estimates its cash reserves are sufficient to fund operations into Q1 2026.
Negative Updates
Clinical Hold on BX004 U.S. Trial Sites
The FDA placed a clinical hold on BX004 U.S. trial sites due to concerns with a third-party nebulizer device, not the drug candidate itself. This temporary pause affects U.S. sites while awaiting further FDA feedback, although European enrollment continues as planned.
Decreased Cash Balance and Net Loss
Cash balance and restricted cash decreased to $8.1 million as of September 30, 2025, from $18 million at the end of 2024, mainly due to net cash used in operating activities. The net loss for Q3 2025 was $9.2 million, compared to a net income of $9.6 million in Q3 2024, influenced by changes in the fair value of warrants.
Company Guidance
During the BiomX Third Quarter 2025 Financial Results and Program Update Conference Call, the company provided guidance on several metrics. BiomX reported a cash balance of $8.1 million as of September 30, 2025, with expectations that this would fund operations into the first quarter of 2026. Research and development expenses decreased to $6.1 million from $7.3 million in the same quarter of 2024, largely due to workforce reductions and lower rent expenses. The company also noted a net loss of $9.2 million for the quarter, compared to a net income of $9.6 million the previous year, primarily due to changes in the fair value of warrants from its March 2024 financing. Additionally, BiomX is advancing its lead programs, BX004 and BX011, with regulatory engagement and clinical trial progress, despite a temporary FDA clinical hold on BX004 due to a third-party nebulizer device. They expect to report BX004 Phase IIb data in Q1 2026 and have received positive FDA feedback for BX011's development pathway.

BiomX Financial Statement Overview

Summary
BiomX faces significant financial challenges with persistent negative revenues and high operating losses. The balance sheet shows high leverage, and the cash flow statements indicate a reliance on external financing. Despite some improvements in net income and stockholders' equity, the company's overall financial health is strained.
Income Statement
BiomX has consistently reported negative revenues and gross profit over the years, indicating significant challenges in generating income. The company has also faced substantial net losses, although a notable improvement in net income was seen in 2024. The lack of revenue growth and negative margins, such as EBIT and EBITDA, highlight ongoing difficulties in achieving profitability.
Balance Sheet
The company's balance sheet shows high leverage, with a significant amount of total debt relative to equity, resulting in a concerning debt-to-equity ratio. However, the equity ratio indicates that a reasonable portion of the company's assets are financed by equity. Despite recent improvements in stockholders' equity, the overall financial stability remains a concern due to the high liabilities.
Cash Flow
BiomX's cash flow statements reflect ongoing negative free cash flow, indicating cash outflows from operations and investments. While there is a trend of securing financing to support cash needs, this reliance on external funding poses risks. The operating cash flow to net income ratio shows significant cash outflows relative to earnings, underscoring financial pressure.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-292.00K-1.80M-871.00K0.000.000.00
EBITDA-29.88M-13.13M-22.82M-23.66M-32.90M-29.60M
Net Income-37.38M-17.73M-26.17M-28.32M-36.23M-30.09M
Balance Sheet
Total Assets26.17M43.23M25.03M45.53M77.99M70.36M
Cash, Cash Equivalents and Short-Term Investments7.91M17.81M14.91M33.33M62.10M56.33M
Total Debt6.58M9.58M15.09M19.36M20.02M5.89M
Total Liabilities15.68M19.09M21.95M24.49M30.45M12.89M
Stockholders Equity10.49M24.15M3.08M21.04M47.53M57.47M
Cash Flow
Free Cash Flow-28.31M-37.01M-21.34M-29.20M-31.25M-25.46M
Operating Cash Flow-28.29M-36.98M-21.29M-29.09M-27.57M-24.45M
Investing Cash Flow106.00K715.00K1.95M-2.11M16.17M-10.86M
Financing Cash Flow11.54M38.37M2.90M292.00K37.28M134.00K

BiomX Technical Analysis

Technical Analysis Sentiment
Negative
Last Price2.24
Price Trends
50DMA
4.68
Negative
100DMA
7.49
Negative
200DMA
8.52
Negative
Market Momentum
MACD
-0.68
Negative
RSI
37.89
Neutral
STOCH
80.63
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PHGE, the sentiment is Negative. The current price of 2.24 is above the 20-day moving average (MA) of 2.07, below the 50-day MA of 4.68, and below the 200-day MA of 8.52, indicating a neutral trend. The MACD of -0.68 indicates Negative momentum. The RSI at 37.89 is Neutral, neither overbought nor oversold. The STOCH value of 80.63 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for PHGE.

BiomX Risk Analysis

BiomX disclosed 72 risk factors in its most recent earnings report. BiomX reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BiomX Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$41.81M-7.41-32.92%-44.31%-34.17%
43
Neutral
$3.42M-0.07-154.50%54.25%
41
Neutral
$5.68M
38
Underperform
$7.88M-1.40-49.00%47.17%26.84%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PHGE
BiomX
2.24
-11.45
-83.64%
CANF
Can-Fite BioPharma
4.36
-27.04
-86.11%
LPCN
Lipocine
7.53
2.94
64.05%
IMRN
Immuron
0.82
-1.15
-58.38%
OSRH
OSR Holdings
0.62
-10.82
-94.56%

BiomX Corporate Events

Business Operations and Strategy
BiomX Subsidiary Terminates Maryland Facility Lease Agreement
Negative
Jan 7, 2026

On December 31, 2025, Adaptive Phage Therapeutics, LLC (APT), a wholly owned subsidiary of the Company, entered into a Seventh Amendment to its lease for premises in Gaithersburg, Maryland, resulting in the termination of the lease effective the same date. Under the settlement, APT agreed to a one-time payment of $800,000 and acknowledged the landlord’s draw on an existing letter of credit for $153,557.68, with the landlord agreeing, upon satisfaction of specified conditions, to release APT and the parent company from further obligations and liabilities under the lease, aside from limited surviving obligations, thereby resolving outstanding lease-related claims and closing out the company’s commitments at that facility.

The most recent analyst rating on (PHGE) stock is a Hold with a $2.00 price target. To see the full list of analyst forecasts on BiomX stock, see the PHGE Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
BiomX Announces New Preferred Stock Financing and Warrants
Positive
Dec 29, 2025

On December 26, 2025, BiomX Inc. entered into a Securities Purchase Agreement with a single investor for a private placement of 3,300 shares of newly created Series Y Convertible Preferred Stock, with an aggregate stated value of $3.3 million, and accompanying warrants to purchase 3,300,000 shares of common stock, for expected gross proceeds of $3.0 million before fees. The Series Y Preferred Stock carries a 15% annual dividend payable in cash or stock, ranks senior to common stock and existing Series X preferred stock, has a one-year maturity, and is initially convertible at $2.00 per share, while the warrants are immediately exercisable at $2.00 per share for five years, with both instruments subject to price adjustments and a 19.99% beneficial ownership cap until stockholder approval is obtained. As part of the deal, the investor secured board representation rights tied to ownership thresholds, BiomX committed to seek stockholder approval within 60 days to permit issuance of more than 19.99% of its outstanding common shares, and it granted registration rights for resale of the underlying securities, signaling a significant equity financing that could meaningfully dilute existing shareholders but strengthens the company’s balance sheet and brings in an influential strategic investor; H.C. Wainwright & Co. acted as exclusive placement agent and will receive fees and additional warrants, and the transaction is expected to close on or about December 30, 2025, subject to customary conditions.

The most recent analyst rating on (PHGE) stock is a Buy with a $26.00 price target. To see the full list of analyst forecasts on BiomX stock, see the PHGE Stock Forecast page.

Business Operations and StrategyLegal Proceedings
BiomX Discontinues Study and Files for Insolvency
Negative
Dec 11, 2025

On December 8, 2025, BiomX Inc. announced the discontinuation of its Phase 2b study due to resource constraints, which led to the decision to file for insolvency proceedings for its Israeli subsidiary, BiomX Ltd. The company is now evaluating strategic options while maintaining its BX011 program for diabetic foot infections.

The most recent analyst rating on (PHGE) stock is a Buy with a $26.00 price target. To see the full list of analyst forecasts on BiomX stock, see the PHGE Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
BiomX Discontinues Phase 2b Trial for BX004
Negative
Dec 8, 2025

On December 8, 2025, BiomX Inc. announced the discontinuation of its Phase 2b clinical trial for BX004, a treatment for Cystic Fibrosis associated with chronic Pseudomonas aeruginosa infections, due to resource constraints. The company is now focusing on advancing its bacteriophage-based therapeutics, particularly BX011 for diabetic foot infections, while also implementing cost-cutting measures and exploring strategic alternatives.

The most recent analyst rating on (PHGE) stock is a Buy with a $26.00 price target. To see the full list of analyst forecasts on BiomX stock, see the PHGE Stock Forecast page.

Business Operations and StrategyPrivate Placements and FinancingProduct-Related AnnouncementsRegulatory Filings and Compliance
BiomX Updates on Phase 2b Study for BX004
Negative
Nov 25, 2025

On November 25, 2025, BiomX Inc. announced updates regarding its Phase 2b study of BX004 for Cystic Fibrosis treatment, which faced a clinical hold by the FDA due to concerns over a third-party nebulizer device. The company is actively working with the manufacturer to resolve these issues and anticipates resuming U.S. enrollment once resolved and financing is secured. Additionally, an independent Data Monitoring Committee recommended continuing the study with an adjusted dosing regimen after a safety review, with topline results expected in the second quarter of 2026, contingent on financial resources.

The most recent analyst rating on (PHGE) stock is a Buy with a $26.00 price target. To see the full list of analyst forecasts on BiomX stock, see the PHGE Stock Forecast page.

Executive/Board ChangesShareholder MeetingsStock Split
BiomX Approves Key Proposals at Annual Meeting
Neutral
Oct 17, 2025

On October 16, 2025, BiomX Inc. held its Annual Meeting of Stockholders, where all proposed business items were approved. Stockholders elected three Class II directors to the board, authorized a potential reverse stock split, and ratified the selection of Kesselman & Kesselman as the independent public accounting firm for fiscal 2025. These decisions could impact the company’s governance and financial structure, potentially influencing its market positioning and operational strategies.

The most recent analyst rating on (PHGE) stock is a Buy with a $15.00 price target. To see the full list of analyst forecasts on BiomX stock, see the PHGE Stock Forecast page.

Product-Related AnnouncementsRegulatory Filings and Compliance
BiomX Faces FDA Questions on Nebulizer Device
Negative
Oct 17, 2025

On October 17, 2025, BiomX Inc. announced that the FDA had raised additional questions regarding the nebulizer device used in their Phase 2b study for the drug candidate BX004, aimed at treating Cystic Fibrosis. The company is continuing its study in Europe and plans to incorporate FDA feedback into future development plans, with topline results expected in early 2026.

The most recent analyst rating on (PHGE) stock is a Buy with a $15.00 price target. To see the full list of analyst forecasts on BiomX stock, see the PHGE Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 08, 2026