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Bolt Biotherapeutics (BOLT)
NASDAQ:BOLT

Bolt Biotherapeutics (BOLT) AI Stock Analysis

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BOLT

Bolt Biotherapeutics

(NASDAQ:BOLT)

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Neutral 48 (OpenAI - 5.2)
Rating:48Neutral
Price Target:
$7.00
▲(18.64% Upside)
The score is primarily held down by weak financial performance, driven by large ongoing losses, heavy cash burn, and rising leverage as equity declines. Technicals provide a partial offset with improving short-to-medium term momentum, but the longer-term trend remains mixed. Valuation is not supportive because profitability is negative and there is no dividend yield data.
Positive Factors
Boltbody targeted delivery platform
The Boltbody platform provides a structural competitive advantage by concentrating innate-immune agonists at tumors, potentially improving efficacy and reducing systemic toxicity. This modality-level differentiation supports durable IP, licensing appeal, and strategic partnering opportunities over months to years.
Clinical-stage pipeline (lead BDC-1001)
Having clinical-stage assets like BDC-1001 shifts value creation toward data-driven de-risking events (trials, readouts). Successful readouts can materially derisk programs and unlock milestone/licensing revenue, making the company attractive to partners and enabling non-dilutive financing pathways long term.
Positive revenue growth trend
Although revenue is small, consistent TTM growth indicates initial commercial, collaboration, or service traction. Sustained revenue expansion can validate translational progress, diversify cash sources, and reduce reliance on capital markets, improving durability of operations over the next several quarters.
Negative Factors
High and persistent cash burn
Large negative operating and free cash flow signals ongoing financing dependence; rapid cash depletion threatens trial timelines and forces equity/debt raises. Repeated fundraising risks dilution and compresses optionality, leaving strategic choices constrained absent partnership or clinical success.
Deep ongoing losses
Substantial negative EBIT and net losses reflect lack of sustainable profitability and long runway to commercial breakeven. Continued operating deficits erode retained capital, limit reinvestment, and increase dependence on external funding, amplifying execution risk for development programs.
Rising leverage and weakened equity base
Higher leverage and shrinking equity reduce financial flexibility and increase refinancing risk. With limited cash generation, elevated debt burdens constrain the company's ability to fund trials internally and weaken negotiating power for partnerships, raising dilution and downside risk.

Bolt Biotherapeutics (BOLT) vs. SPDR S&P 500 ETF (SPY)

Bolt Biotherapeutics Business Overview & Revenue Model

Company DescriptionBolt Biotherapeutics, Inc., a clinical-stage biotechnology company, engages in the development of immuno-oncology agents to target tumor cells for elimination by the immune system. The company is developing BDC-1001, a human epidermal growth factor receptor 2 (HER2), which is in Phase I/II clinical trial for the treatment of patients with HER2-expressing solid tumors, including HER2-low tumors; BDC-2034, a carcinoembryonic antigen program for colorectal, non-small cell lung, pancreatic, and breast cancers; and BDC-3042, a Dectin-2 agonist antibody program developed to repolarize critical cells in the tumor microenvironment by targeting cell-surface receptors on macrophages. It is also developing programmed cell death-ligand 1 program for tumors that are nonresponsive to immune checkpoint blockade. The company was formerly known as Bolt Therapeutics, Inc. and changed its name to Bolt Biotherapeutics, Inc. in July 2015. Bolt Biotherapeutics, Inc. was incorporated in 2015 and is headquartered in Redwood city, California.
How the Company Makes MoneyBolt Biotherapeutics generates revenue primarily through the advancement of its proprietary drug candidates and strategic collaborations with pharmaceutical companies. The company's revenue model includes potential milestone payments from partnerships, royalties on future product sales, and funding from government grants and research institutions. Significant partnerships with larger biotech and pharmaceutical firms provide Bolt with financial support and resources to accelerate its research and development efforts, while also enabling shared risk in the development of new therapies. As Bolt progresses its clinical trials and achieves development milestones, it has the potential to unlock additional revenue streams through licensing agreements or partnerships.

Bolt Biotherapeutics Financial Statement Overview

Summary
Financial profile is weak: the company remains deeply unprofitable (TTM EBIT -$44.7M; net loss -$42.7M) with significant ongoing cash burn (TTM operating cash flow -$47.1M; free cash flow -$47.2M). Revenue growth exists (TTM revenue $5.2M, ~24.7% growth) but is small relative to losses. Balance sheet leverage has increased as equity has weakened (debt ~$23.6M vs equity ~$32.1M; debt-to-equity ~0.73), increasing financing and dilution risk if burn persists.
Income Statement
18
Very Negative
Bolt Biotherapeutics remains deeply unprofitable despite modest top-line expansion. Revenue in TTM (Trailing-Twelve-Months) is $5.2M with ~24.7% growth, but losses are substantial (EBIT of -$44.7M; net income of -$42.7M), resulting in very negative profitability. Gross profit is positive in TTM, but margins and earnings have been volatile across annual periods, and the business has not yet demonstrated a path to sustainable profitability.
Balance Sheet
46
Neutral
The balance sheet shows moderate leverage but weakening capitalization over time. In TTM (Trailing-Twelve-Months), total debt is ~$23.6M versus equity of ~$32.1M (debt-to-equity ~0.73), which is meaningfully higher leverage than prior years when equity was stronger. Total assets are ~$65.1M, and returns on equity are sharply negative, reflecting continued losses and a shrinking equity base—raising financial flexibility and dilution/financing risk if cash burn persists.
Cash Flow
14
Very Negative
Cash generation is a key concern. TTM (Trailing-Twelve-Months) operating cash flow is -$47.1M and free cash flow is -$47.2M, with free cash flow trending worse versus the prior period (negative growth). While cash outflow broadly tracks accounting losses (free cash flow roughly in line with net loss), the scale of ongoing cash burn implies continued dependence on external funding.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue5.20M7.69M7.88M5.73M1.26M231.00K
Gross Profit4.48M7.69M-53.67M-67.39M-74.39M-40.13M
EBITDA-42.94M-66.45M-74.34M-88.66M-91.59M-48.57M
Net Income-42.68M-63.12M-69.20M-88.10M-98.59M-60.73M
Balance Sheet
Total Assets65.05M99.63M159.78M227.81M307.72M46.54M
Cash, Cash Equivalents and Short-Term Investments31.91M47.32M102.19M168.89M186.22M22.84M
Total Debt23.59M25.21M20.22M22.61M24.36M10.88M
Total Liabilities32.95M42.43M47.04M56.30M57.60M151.49M
Stockholders Equity32.10M57.20M112.74M171.51M250.12M-104.95M
Cash Flow
Free Cash Flow-47.20M-61.33M-69.73M-78.46M-59.40M-50.57M
Operating Cash Flow-47.12M-61.29M-69.53M-76.50M-57.07M-47.31M
Investing Cash Flow55.46M57.58M71.04M57.86M-232.20M-20.59M
Financing Cash Flow43.00K108.00K253.00K503.00K311.11M39.60M

Bolt Biotherapeutics Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price5.90
Price Trends
50DMA
5.64
Positive
100DMA
5.53
Positive
200DMA
5.81
Positive
Market Momentum
MACD
0.23
Positive
RSI
47.18
Neutral
STOCH
22.30
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BOLT, the sentiment is Neutral. The current price of 5.9 is below the 20-day moving average (MA) of 6.22, above the 50-day MA of 5.64, and above the 200-day MA of 5.81, indicating a neutral trend. The MACD of 0.23 indicates Positive momentum. The RSI at 47.18 is Neutral, neither overbought nor oversold. The STOCH value of 22.30 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for BOLT.

Bolt Biotherapeutics Risk Analysis

Bolt Biotherapeutics disclosed 64 risk factors in its most recent earnings report. Bolt Biotherapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Bolt Biotherapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$19.24M-0.30-189.72%70.57%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$11.32M-0.26-81.97%-46.88%34.83%
42
Neutral
$5.09M-1.08-57.43%13.30%22.70%
42
Neutral
$7.04M-0.76-418.83%98.58%
41
Neutral
$3.16M-0.07-404.48%-59.21%68.97%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BOLT
Bolt Biotherapeutics
5.90
-4.30
-42.16%
ERNA
Eterna Therapeutics
1.22
-4.20
-77.49%
XBIO
Xenetic Biosciences
2.22
-1.84
-45.32%
MBIO
Mustang Bio
0.97
-3.04
-75.88%
LYRA
Lyra Therapeutics
1.78
-7.34
-80.48%
INAB
IN8bio
1.97
-5.56
-73.84%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 13, 2026