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Panbela Therapeutics (PBLA)
OTHER OTC:PBLA
US Market

Panbela Therapeutics (PBLA) AI Stock Analysis

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PBLA

Panbela Therapeutics

(OTC:PBLA)

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Underperform 37 (OpenAI - 4o)
Rating:37Underperform
Price Target:
Action:N/ADate:01/31/25
Panbela Therapeutics faces significant financial instability, with no revenue and negative equity, which are major concerns. While there are positive developments in clinical trials and strategic investments, the ongoing financial challenges and reliance on external funding heavily weigh down the score. The technical indicators and valuation metrics provide little support, reflecting limited investor confidence.
Positive Factors
Strategic Investment
This investment demonstrates confidence in Panbela's approach and provides crucial financial support, enabling continued R&D and clinical trials.
Clinical Trial Progress
Progress in the ASPIRE trial suggests potential improvements in patient outcomes, enhancing Panbela's competitive position in cancer treatment.
FDA Approval
FDA approval of eflornithine validates Panbela's polyamine-focused approach, potentially opening new revenue streams and enhancing market credibility.
Negative Factors
Financial Instability
Ongoing financial losses highlight significant operational challenges and reliance on external funding, which may impact long-term viability.
Cash Flow Concerns
Low cash reserves indicate potential liquidity issues, necessitating continuous external funding to sustain operations and strategic initiatives.
Negative Equity
Negative equity reflects financial instability, posing a risk of insolvency and limiting the company's ability to secure favorable financing terms.

Panbela Therapeutics (PBLA) vs. SPDR S&P 500 ETF (SPY)

Panbela Therapeutics Business Overview & Revenue Model

Company DescriptionPanbela Therapeutics, Inc., a clinical-stage biopharmaceutical company, together with its subsidiaries, focuses on developing disruptive therapeutics for the treatment of patients with cancer. The company focuses on diseases of the pancreas, including pancreatitis and pancreatic cancer, as well as neoadjuvant pancreatic cancer, colorectal cancer, ovarian cancer, and other agents in other cancer indications. Its lead product candidate is SBP-101, which is in Phase Ia/Ib clinical trial for the treatment of patients with metastatic pancreatic ductal adenocarcinoma. The company was formerly known as Sun BioPharma, Inc. and changed its name to Panbela Therapeutics, Inc. in December 2020. Panbela Therapeutics, Inc. was incorporated in 2011 and is based in Waconia, Minnesota.
How the Company Makes MoneyPanbela Therapeutics generates revenue primarily through the development and commercialization of its proprietary cancer therapies. The company invests heavily in research and development to bring its innovations from the lab to the market. Potential revenue streams include licensing agreements with larger pharmaceutical companies, milestone payments based on the achievement of clinical and regulatory benchmarks, and future sales of approved therapies. Panbela may also receive funding through strategic partnerships, grants, and potential collaborations with academic and research institutions dedicated to cancer treatment advancements. As these therapies progress through clinical trials and regulatory approvals, Panbela aims to establish a robust market presence and generate significant revenue from the commercial distribution of its products.

Panbela Therapeutics Financial Statement Overview

Summary
Panbela Therapeutics is facing significant financial challenges with no revenue and consistent losses, leading to negative equity and a reliance on financing for cash flow. The biotechnology industry often requires substantial investment before profitability; however, the current trajectory highlights significant financial instability and risk.
Income Statement
10
Very Negative
Panbela Therapeutics has consistently reported negative gross profit, EBIT, and net income over the past several years, with no revenue generated. This indicates a challenging financial position with high operational costs and no income to offset these expenses. The company lacks revenue growth, which is crucial for financial improvement.
Balance Sheet
15
Very Negative
The company's balance sheet shows negative stockholders' equity, indicating liabilities exceed assets. The debt-to-equity ratio cannot be calculated due to negative equity, posing a risk of insolvency. The equity ratio is also negative, reflecting weak financial stability.
Cash Flow
20
Very Negative
Panbela Therapeutics has negative free cash flow, suggesting it is not generating enough cash to sustain operations and relies heavily on financing activities. However, the company has maintained some cash flow through financing, which indicates a potential to manage short-term liquidity needs.
BreakdownTTMDec 2023Dec 2022Dec 2021Dec 2020Dec 2019
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-29.04M-25.65M-35.73M-10.01M-5.75M-4.32M
EBITDA-26.40M-51.29M-34.74M-10.61M-5.05M-4.42M
Net Income-27.91M-25.26M-34.93M-10.13M-4.77M-6.20M
Balance Sheet
Total Assets5.17M11.80M4.98M12.87M9.81M3.14M
Cash, Cash Equivalents and Short-Term Investments142.00K2.58M1.28M11.87M9.02M2.45M
Total Debt6.39M5.19M6.84M0.000.00116.00K
Total Liabilities23.34M16.51M13.03M2.66M1.36M1.76M
Stockholders Equity-18.17M-4.71M-8.05M10.21M8.45M1.39M
Cash Flow
Free Cash Flow-15.57M-25.25M-15.94M-6.70M-3.85M-2.74M
Operating Cash Flow-15.57M-25.25M-15.28M-6.70M-3.85M-2.74M
Investing Cash Flow-7.97M400.00K-656.00K-540.00K0.000.00
Financing Cash Flow14.03M26.14M5.35M10.10M10.44M3.78M

Panbela Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.01
Price Trends
50DMA
0.01
Negative
100DMA
0.04
Negative
200DMA
0.15
Negative
Market Momentum
MACD
>-0.01
Negative
RSI
40.61
Neutral
STOCH
-3.70
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PBLA, the sentiment is Negative. The current price of 0.01 is below the 20-day moving average (MA) of 0.01, below the 50-day MA of 0.01, and below the 200-day MA of 0.15, indicating a bearish trend. The MACD of >-0.01 indicates Negative momentum. The RSI at 40.61 is Neutral, neither overbought nor oversold. The STOCH value of -3.70 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for PBLA.

Panbela Therapeutics Risk Analysis

Panbela Therapeutics disclosed 34 risk factors in its most recent earnings report. Panbela Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Panbela Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$732.72K-0.07178.82%-4121.10%
41
Neutral
$693.87K-0.02-60.37%-100.00%86.75%
37
Underperform
$53.89K
29
Underperform
$2.94M-0.05-168.95%90.27%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PBLA
Panbela Therapeutics
0.01
-0.41
-97.38%
BDRX
Biodexa Pharmaceuticals
1.13
-33.37
-96.72%
QCLS
Q/C Technologies
3.86
-39.11
-91.02%
SCNI
Scinai Immunotherapeutics
0.91
-2.63
-74.26%
OGEN
Oragenics
0.79
-7.37
-90.29%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 31, 2025