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Oncotelic Therapeutics (OTLC)
OTHER OTC:OTLC
US Market
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Oncotelic Therapeutics (OTLC) AI Stock Analysis

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OTLC

Oncotelic Therapeutics

(OTC:OTLC)

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Neutral 49 (OpenAI - 5.2)
Rating:49Neutral
Price Target:
$0.04
▼(-45.00% Downside)
Action:Reiterated
Date:06/03/26
The score is held down primarily by weak financial performance (minimal revenue, persistent losses, and ongoing cash burn). Partially offsetting this are a low P/E screen, mixed-to-improving technical indicators (positive MACD with neutral RSI), and a series of positive corporate developments around IP access, partnerships, and platform progress.
Positive Factors
Strategic IP Access
The Lunai merger gave Oncotelic preferred shares and a broad, perpetual license to exploit transferred IP outside biodefense and Alzheimer’s. That durable access strengthens its R&D platform, reduces time-to-development for follow-ons, and enables licensing or partnering strategies without near-term cash outlay.
Negative Factors
Cash Flow Deficit
Operating and free cash flow are structurally negative across reported periods, signaling persistent cash burn and no self-funding path. This forces recurring external financing, constrains sustained R&D investment, increases dilution risk, and limits financial flexibility over the medium term.
Read all positive and negative factors
Positive Factors
Negative Factors
Strategic IP Access
The Lunai merger gave Oncotelic preferred shares and a broad, perpetual license to exploit transferred IP outside biodefense and Alzheimer’s. That durable access strengthens its R&D platform, reduces time-to-development for follow-ons, and enables licensing or partnering strategies without near-term cash outlay.
Read all positive factors

Oncotelic Therapeutics (OTLC) vs. SPDR S&P 500 ETF (SPY)

Oncotelic Therapeutics Business Overview & Revenue Model

Company Description
Oncotelic Therapeutics, Inc., an Agoura Hills, California-based clinical-stage biopharmaceutical company, specializes in developing therapeutics for rare oncological conditions. Its flagship therapeutic candidate, OT-101 – an antisense compound de...
How the Company Makes Money
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Oncotelic Therapeutics Financial Statement Overview

Summary
Financials reflect an early-stage biotech profile: revenue is effectively minimal, operating results and net income are deeply negative on a TTM basis, and operating/free cash flow remain negative (ongoing cash burn). The main offset is modest recent leverage (low debt-to-equity), but overall earnings quality and financial stability are weak.
Income Statement
12
Very Negative
Balance Sheet
48
Neutral
Cash Flow
18
Very Negative
BreakdownMar 2026Mar 2025Dec 2023Mar 2023Mar 2022
Income Statement
Total Revenue0.000.0070.00K0.000.00
Gross Profit0.000.0070.00K-12.84K-61.51K
EBITDA198.05B-3.55M-7.16M-5.60M-9.06M
Net Income249.28M-4.52B-7.90M17.82M-11.39M
Balance Sheet
Total Assets10.00T>26.68M30.01M36.12M23.61M
Cash, Cash Equivalents and Short-Term Investments88.86B86.13K170.41K241.45K568.77K
Total Debt16.27T13.09M12.57M11.26M8.99M
Total Liabilities10.00T>19.20M18.40M16.92M15.45M
Stockholders Equity10.00T>8.25M12.13M19.41M7.96M
Cash Flow
Free Cash Flow-1.38T-740.27K-1.32M-1.45M-4.43M
Operating Cash Flow-1.38T-740.27K-1.32M-1.45M-4.43M
Investing Cash Flow0.000.000.000.000.00
Financing Cash Flow1.39T656.00K1.25M1.13M4.53M

Oncotelic Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.08
Price Trends
50DMA
0.05
Negative
100DMA
0.05
Negative
200DMA
0.06
Negative
Market Momentum
MACD
>-0.01
Positive
RSI
37.88
Neutral
STOCH
<0.01
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For OTLC, the sentiment is Negative. The current price of 0.08 is above the 20-day moving average (MA) of 0.05, above the 50-day MA of 0.05, and above the 200-day MA of 0.06, indicating a bearish trend. The MACD of >-0.01 indicates Positive momentum. The RSI at 37.88 is Neutral, neither overbought nor oversold. The STOCH value of <0.01 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for OTLC.

Oncotelic Therapeutics Risk Analysis

Oncotelic Therapeutics disclosed 38 risk factors in its most recent earnings report. Oncotelic Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Oncotelic Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$49.25M-2.81-0.97%21.67%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$44.16M0.76-560.64%-32.64%56.66%
49
Neutral
$19.78M0.07-38.38%
47
Neutral
$12.89M-0.74-526.36%16.33%
45
Neutral
$38.73M-3.62-12.66%43.67%
$85.73M-2.16-284.80%16.55%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OTLC
Oncotelic Therapeutics
0.04
>-0.01
-2.27%
GRCE
Grace Therapeutics
2.30
-0.67
-22.56%
LTRN
Lantern Pharma
4.07
0.91
28.80%
CALC
CalciMedica
0.99
-0.61
-38.31%
ELUT
Elutia
0.96
-1.02
-51.72%
MAIA
MAIA Biotechnology, Inc.
1.48
-0.32
-17.78%

Oncotelic Therapeutics Corporate Events

Business Operations and StrategyPrivate Placements and Financing
Oncotelic Therapeutics Enters New Convertible Note Financing
Neutral
Jun 29, 2026
On June 23, 2026, Oncotelic Therapeutics, Inc. entered into a Securities Purchase Agreement with Pacific Pier Capital II, LP and issued a $178,410 convertible promissory note carrying a 12% original issue discount and 12% annual interest, maturing...
Business Operations and StrategyM&A Transactions
Oncotelic Secures Lunai Stake and IP License Rights
Positive
May 5, 2026
On May 1, 2026, Oncotelic Therapeutics completed a merger in which its affiliate Holdings was merged into Merger Sub, making Merger Sub a wholly owned subsidiary of Lunai, and in exchange Oncotelic received five shares of Lunai&#8217;s Series B pr...
Business Operations and StrategyFinancial Disclosures
Oncotelic Therapeutics Posts Transformational 2025 Profit Surge
Positive
Apr 16, 2026
On April 16, 2026, Oncotelic Therapeutics reported financial results for the year ended December 31, 2025, posting net income of about $249 million versus a $4.8 million loss in 2024, largely due to a non-cash $365.4 million uplift in the fair val...
Business Operations and StrategyProduct-Related Announcements
Oncotelic forms AI-driven robotics partnership for GMP automation
Positive
Apr 2, 2026
On April 2, 2026, Oncotelic Therapeutics, Inc., a clinical-stage biotechnology company focused on oncology and AI-driven solutions, announced a strategic partnership with TechForce Robotics to commercialize an integrated PDAOAI-enabled, GMP-compli...
Business Operations and StrategyProduct-Related Announcements
Oncotelic Subsidiary Showcases Deciparticle Platform at BIO-Europe
Positive
Mar 30, 2026
On March 24, 2026, Oncotelic Therapeutics, Inc., a biotechnology company specializing in RNA-based cancer therapeutics and rare pediatric oncology, announced that its subsidiary Sapu Nano will showcase its Deciparticle nanomedicine platform at BIO...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 03, 2026