tiprankstipranks
Trending News
More News >
MAIA Biotechnology, Inc. (MAIA)
:MAIA
US Market

MAIA Biotechnology, Inc. (MAIA) AI Stock Analysis

Compare
311 Followers

Top Page

MAIA

MAIA Biotechnology, Inc.

(MAIA)

Select Model
Select Model
Select Model
Neutral 44 (OpenAI - 4o)
Rating:44Neutral
Price Target:
MAIA Biotechnology presents a mixed outlook. The company's financial performance is weak due to its development-stage status and lack of revenue, contributing to a low financial performance score. However, recent positive trial results and technical indicators showing short-term upward momentum provide a more optimistic view. Valuation remains challenging due to negative earnings, but the potential for significant clinical advancements offers upside potential.
Positive Factors
Clinical Trial Success
The promising results from the Phase 2 THIO-101 trial indicate a potential breakthrough in cancer treatment, enhancing MAIA's regulatory strategy and expediting FDA approval, which could significantly boost the company's market position and revenue potential.
Intellectual Property Strength
Securing a European patent strengthens MAIA's intellectual property portfolio, providing a competitive advantage in the oncology market and protecting its proprietary technology, which is crucial for long-term revenue generation and market exclusivity.
Leadership Stability
Enhancing executive compensation packages aligns leadership incentives with corporate goals, ensuring stability and continuity in strategic direction, which is vital for navigating the complex biotech landscape and achieving long-term success.
Negative Factors
Lack of Revenue
The absence of revenue generation reflects the company's early-stage status and reliance on external funding, posing a risk to financial sustainability and limiting its ability to self-fund R&D and operational activities in the long term.
Negative Cash Flow
Consistently negative cash flow underscores the company's dependency on external financing to maintain operations, which could lead to dilution of equity or increased debt, impacting financial flexibility and long-term viability.
Limited Financial Flexibility
Limited stockholders' equity restricts MAIA's financial flexibility, making it challenging to absorb operational shocks or invest in growth opportunities without seeking additional external funding, which could affect its competitive positioning.

MAIA Biotechnology, Inc. (MAIA) vs. SPDR S&P 500 ETF (SPY)

MAIA Biotechnology, Inc. Business Overview & Revenue Model

Company DescriptionMAIA Biotechnology, Inc., a clinical stage biotechnology company, engages in the discovery, development, and commercialization of therapies targeting cancer, primarily non-small cell lung cancer. Its lead asset, THIO, is an investigational dual mechanism of action drug candidate incorporating telomere targeting and immunogenicity. The company was founded in 2018 and is headquartered in Chicago, Illinois.
How the Company Makes MoneyMAIA Biotechnology, Inc. makes money primarily through the development and commercialization of oncology therapies. The company's revenue model includes securing funding through partnerships, licensing agreements, and collaborations with other pharmaceutical companies. These partnerships often involve milestone payments, royalties, and upfront fees linked to the development and eventual commercialization of their drug candidates. Additionally, MAIA may also receive government grants or research funding to support its clinical trials and research activities. As the company progresses its drug candidates through clinical trials and towards regulatory approval, it aims to generate revenue through the successful commercialization of these therapies.

MAIA Biotechnology, Inc. Financial Statement Overview

Summary
MAIA Biotechnology, Inc. is in a development phase with no revenue and significant ongoing expenses leading to negative profitability and cash flows. The balance sheet is strengthened by zero debt, but equity is limited. The financial outlook depends heavily on successful future product development and potential funding opportunities.
Income Statement
15
Very Negative
MAIA Biotechnology, Inc. shows no revenue generation, typical for early-stage biotech firms focusing on R&D. The company has consistently reported negative EBIT and net income, reflecting the high costs associated with drug development without corresponding revenue. This creates a challenging profitability outlook in the short term.
Balance Sheet
25
Negative
The balance sheet highlights a low debt profile with no outstanding debt, which is positive. However, the stockholders' equity is relatively small, limiting financial flexibility. The company's equity ratio is marginal and has fluctuated over the years, indicating potential volatility in financial stability.
Cash Flow
20
Very Negative
Operating cash flow has been consistently negative due to ongoing operational expenses without revenue. Free cash flow remains deeply negative, though financing activities have helped maintain liquidity. The cash flow situation reflects a need for external funding to support operations.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit0.000.000.000.000.000.00
EBITDA-10.13M-23.25M-19.77M-15.76M-11.75M0.00
Net Income-22.34M-23.25M-19.77M-15.77M-12.50M-6.64M
Balance Sheet
Total Assets11.78M10.16M7.57M12.02M11.33M746.50K
Cash, Cash Equivalents and Short-Term Investments10.89M9.60M7.15M10.95M10.57M663.46K
Total Debt0.000.000.000.000.00463.75K
Total Liabilities11.74M6.52M7.09M3.51M2.15M2.36M
Stockholders Equity41.67K3.63M477.51K8.51M9.18M-3.34M
Cash Flow
Free Cash Flow-15.73M-15.70M-13.07M-12.10M-4.12M-1.84M
Operating Cash Flow-15.73M-15.70M-13.07M-12.10M-4.12M-1.84M
Investing Cash Flow0.000.000.000.000.000.00
Financing Cash Flow17.95M18.18M9.27M12.48M14.03M798.05K

MAIA Biotechnology, Inc. Technical Analysis

Technical Analysis Sentiment
Positive
Last Price1.55
Price Trends
50DMA
1.27
Positive
100DMA
1.40
Positive
200DMA
1.57
Positive
Market Momentum
MACD
0.10
Negative
RSI
60.21
Neutral
STOCH
68.87
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MAIA, the sentiment is Positive. The current price of 1.55 is above the 20-day moving average (MA) of 1.46, above the 50-day MA of 1.27, and below the 200-day MA of 1.57, indicating a bullish trend. The MACD of 0.10 indicates Negative momentum. The RSI at 60.21 is Neutral, neither overbought nor oversold. The STOCH value of 68.87 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for MAIA.

MAIA Biotechnology, Inc. Risk Analysis

MAIA Biotechnology, Inc. disclosed 72 risk factors in its most recent earnings report. MAIA Biotechnology, Inc. reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

MAIA Biotechnology, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$33.90M-0.98-908.28%588.40%61.76%
47
Neutral
$59.17M-1.50-98.81%
45
Neutral
$37.56M-1.84-61.92%-100.00%55.10%
44
Neutral
$61.10M-2.22-2691.06%44.50%
43
Neutral
$14.42M-0.99-680.47%
42
Neutral
$43.22M-0.52-115.64%46.20%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MAIA
MAIA Biotechnology, Inc.
1.65
-0.37
-18.32%
VERU
Veru
2.34
-6.10
-72.27%
APLT
Applied Therapeutics
0.10
-0.52
-84.03%
OKUR
OnKure Therapeutics
3.19
-2.82
-46.92%
XLO
Xilio Therapeutics
0.65
-0.49
-43.42%
RADX
Radiopharm Theranostics Limited Sponsored ADR
5.20
<0.01
0.19%

MAIA Biotechnology, Inc. Corporate Events

Business Operations and StrategyPrivate Placements and Financing
MAIA Biotechnology Announces $2.25M Private Placement Deal
Positive
Dec 17, 2025

On December 16, 2025, MAIA Biotechnology, Inc. entered into a Securities Purchase Agreement with accredited investors and directors for a private placement of common stock and warrants worth approximately $2.25 million. The director participation aligns leadership interests with shareholders, and the funds will support Phase II clinical trials of the THIO-101 program as well as general working capital. The transaction is expected to close on December 18, 2025, pending standard closing conditions.

The most recent analyst rating on (MAIA) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on MAIA Biotechnology, Inc. stock, see the MAIA Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
MAIA Biotechnology Announces Significant Insider Buying
Positive
Dec 11, 2025

On December 11, 2025, MAIA Biotechnology, Inc. announced significant insider buying by its leadership, including CEO Dr. Vlad Vitoc, who acquired 182,445 shares in late November 2025. This insider activity, alongside encouraging clinical results from their telomere-targeting cancer therapy, ateganosine, signals strong confidence in the company’s strategy and potential for long-term value creation. The company also announced the dosing of the first patient in the THIO-104 Phase 3 pivotal trial, marking a critical step in evaluating ateganosine as a third-line treatment for advanced non-small cell lung cancer. These developments are seen as pivotal for MAIA’s positioning in the oncology market and its potential impact on stakeholders.

The most recent analyst rating on (MAIA) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on MAIA Biotechnology, Inc. stock, see the MAIA Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
MAIA Biotechnology Advances NSCLC Treatment with Ateganosine
Positive
Dec 10, 2025

On December 10, 2025, MAIA Biotechnology announced a significant advancement in the treatment of advanced non-small cell lung cancer (NSCLC) with their telomere-targeting agent, ateganosine. This new therapeutic class aims to address the unmet medical needs of patients who do not respond to current therapies like checkpoint inhibitors or chemotherapy. The company has received Fast Track Designation from the U.S. FDA and is initiating a Phase 3 trial, positioning itself strategically in the oncology market. The potential success of ateganosine could redefine treatment paradigms for NSCLC and extend its impact across other cancer types, supported by FDA Orphan Drug Designations for glioblastoma, hepatocellular carcinoma, and small cell lung cancer.

The most recent analyst rating on (MAIA) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on MAIA Biotechnology, Inc. stock, see the MAIA Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
MAIA Biotechnology Highlights Ateganosine Progress at SITC 2025
Positive
Nov 21, 2025

On November 21, 2025, MAIA Biotechnology announced the ongoing progress of its ateganosine clinical program at the SITC 2025 conference. The company highlighted the enrollment of 12 patients in the Phase 2 THIO-101 trial and the commencement of patient screening in the Phase 3 THIO-104 trial for NSCLC. The FDA has granted Fast Track designation for ateganosine, which has shown promising results in extending overall survival in patients resistant to current treatments. The trials are expected to advance the development of ateganosine as a novel therapy for NSCLC, potentially leading to early commercial approval and offering new hope for patients with significant unmet medical needs.

The most recent analyst rating on (MAIA) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on MAIA Biotechnology, Inc. stock, see the MAIA Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
MAIA Biotechnology Expands Phase 2 Study in Romania
Positive
Nov 20, 2025

On November 20, 2025, MAIA Biotechnology announced that its CEO, Vlad Vitoc, presented the efficacy of their telomere-targeting agent, ateganosine, at the Smart Diaspora 2025 conference in Romania. The company has begun enrolling patients in Romania for the Phase 2 THIO-101 Part C study, which evaluates ateganosine as a treatment for advanced non-small cell lung cancer. This expansion aims to accelerate patient access to the therapy and strengthen MAIA’s strategy for accelerated approval in the U.S. The study has shown promising results, with a 38% response rate in third-line NSCLC patients, compared to the current treatment’s response rate of up to 6%.

The most recent analyst rating on (MAIA) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on MAIA Biotechnology, Inc. stock, see the MAIA Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
MAIA Biotechnology Presents Posters at Cancer Conference
Positive
Nov 7, 2025

MAIA Biotechnology, Inc. announced the presentation of two posters at the Society for Immunotherapy of Cancer conference in November 2025. The posters detail ongoing Phase 2 and Phase 3 studies of Ateganosine (THIO) in combination with immune checkpoint inhibitors for treating advanced NSCLC resistant to standard therapies, highlighting the company’s commitment to advancing cancer treatment options.

The most recent analyst rating on (MAIA) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on MAIA Biotechnology, Inc. stock, see the MAIA Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
MAIA Biotechnology Presents at 2025 Cancer Conference
Positive
Oct 27, 2025

On October 27, 2025, MAIA Biotechnology announced its participation in the 2025 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, where they presented a trial in progress poster for their THIO-101 Phase 2 clinical trial. The company has enrolled five patients from Taiwan and Turkey in the expansion phase of this trial, which aims to evaluate the anti-tumor activity of ateganosine in combination with immune checkpoint inhibitors for advanced NSCLC patients. This development could offer a promising treatment option for the large and underserved NSCLC patient population, particularly in regions with high lung cancer prevalence due to factors like smoking and air pollution.

The most recent analyst rating on (MAIA) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on MAIA Biotechnology, Inc. stock, see the MAIA Stock Forecast page.

Business Operations and Strategy
MAIA Biotechnology Showcases Promising Cancer Trial Results
Positive
Oct 23, 2025

On October 23, 2025, MAIA Biotechnology announced the presentation of two e-posters at the European Society for Medical Oncology Congress 2025 in Berlin, detailing ongoing Phase 2 and Phase 3 clinical trials of ateganosine in non-small cell lung cancer (NSCLC). A notable highlight was the 30-month survival of a patient in the Phase 2 trial, which underscores the potential efficacy of ateganosine in treating high-risk cancers with limited options. This development could significantly impact MAIA’s position in the oncology market, offering hope for patients resistant to existing therapies.

The most recent analyst rating on (MAIA) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on MAIA Biotechnology, Inc. stock, see the MAIA Stock Forecast page.

Private Placements and Financing
MAIA Biotechnology Announces Private Placement Agreement
Neutral
Oct 14, 2025

On October 13, 2025, MAIA Biotechnology, Inc. announced a Securities Purchase Agreement with accredited investors for a private placement of 603,769 shares of common stock and warrants, raising approximately $736,600. The proceeds will be used to fund the initial costs of Step 1 of Part C of the Phase II trial THIO-101 and for working capital, with the private placement expected to close on October 15, 2025.

The most recent analyst rating on (MAIA) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on MAIA Biotechnology, Inc. stock, see the MAIA Stock Forecast page.

Business Operations and Strategy
MAIA Biotechnology Adopts New Digital Asset Strategy
Positive
Oct 7, 2025

On October 7, 2025, MAIA Biotechnology, Inc. announced a new digital asset treasury strategy, authorizing up to 90% of its liquid assets to be held in cryptocurrencies such as Bitcoin, Ethereum, and USD Coin. This move aims to diversify MAIA’s investment portfolio and enhance value creation for shareholders while maintaining adequate working capital for operations. The company plans to establish a Digital Assets Advisory Board to support this strategy, reflecting a strategic shift towards leveraging the rapidly evolving blockchain space.

The most recent analyst rating on (MAIA) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on MAIA Biotechnology, Inc. stock, see the MAIA Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 03, 2025